D-Glucopyranose, oligomeric, decyl octyl glycosides; Exemption from the Requirement of a Tolerance, 65561-65565 [2013-26241]
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Federal Register / Vol. 78, No. 212 / Friday, November 1, 2013 / Rules and Regulations
disapprove Florida’s submission related
to these requirements. With the
exceptions noted above FDEP has
addressed the elements of the CAA
110(a)(1) and (2) SIP requirements
pursuant to section 110 of the CAA to
ensure that the 2008 8-hour ozone
NAAQS are implemented, enforced, and
maintained in Florida.
IV. Statutory and Executive Order
Reviews
Under the CAA, the Administrator is
required to approve a SIP submission
that complies with the provisions of the
Act and applicable Federal regulations.
42 U.S.C. 7410(k); 40 CFR 52.02(a).
Thus, in reviewing SIP submissions,
EPA’s role is to approve state choices,
provided that they meet the criteria of
the CAA. Accordingly, this proposed
action merely approves state law as
meeting federal requirements and does
not impose additional requirements
beyond those imposed by State law. For
that reason, this proposed action:
• Is not a ‘‘significant regulatory
action’’ subject to review by the Office
of Management and Budget under
Executive Order 12866 (58 FR 51735,
October 4, 1993);
• does not impose an information
collection burden under the provisions
of the Paperwork Reduction Act (44
U.S.C. 3501 et seq.);
• is certified as not having a
significant economic impact on a
substantial number of small entities
under the Regulatory Flexibility Act (5
U.S.C. 601 et seq.);
• does not contain any unfunded
mandate or significantly or uniquely
affect small governments, as described
in the Unfunded Mandates Reform Act
of 1995 (Pub. L. 104–4);
• does not have Federalism
implications as specified in Executive
Order 13132 (64 FR 43255, August 10,
1999);
• is not an economically significant
regulatory action based on health or
safety risks subject to Executive Order
13045 (62 FR 19885, April 23, 1997);
• is not a significant regulatory action
subject to Executive Order 13211 (66 FR
28355, May 22, 2001);
• is not subject to requirements of
Section 12(d) of the National
Technology Transfer and Advancement
Act of 1995 (15 U.S.C. 272 note) because
application of those requirements would
be inconsistent with the CAA; and
• does not provide EPA with the
discretionary authority to address, as
appropriate, disproportionate human
health or environmental effects, using
practicable and legally permissible
methods, under Executive Order 12898
(59 FR 7629, February 16, 1994).
In addition, this proposed rule does not
have tribal implications as specified by
Executive Order 13175 (65 FR 67249,
November 9, 2000), because the SIP is
not approved to apply in Indian country
65561
located in the State, and EPA notes that
it will not impose substantial direct
costs on tribal governments or preempt
tribal law.
List of Subjects in 40 CFR Part 52
Environmental protection, Air
pollution control, Incorporation by
reference, Intergovernmental relations,
Nitrogen dioxide, Ozone, Reporting and
recordkeeping requirements, Volatile
organic compounds.
Dated: October 21, 2013.
Beverly H. Banister
Acting Regional Administrator, Region 4.
40 CFR part 52 is amended as follows:
PART 52—APPROVAL AND
PROMULGATION OF
IMPLEMENTATION PLANS
1. The authority citation for part 52
continues to read as follows:
■
Authority: 42 U.S.C. 7401 et seq.
Subpart K—Florida
2. Section 52.520(e), is amended by
adding a new entry ‘‘110(a)(1) and (2)
Infrastructure Requirements for the 2008
8-Hour Ozone National Ambient Air
Quality Standards’’ at the end of the
table to read as follows:
■
§ 52.520
*
Identification of plan.
*
*
(e) * * *
*
*
EPA-APPROVED FLORIDA NON-REGULATORY PROVISIONS
Provision
*
*
110(a)(1) and (2) Infrastructure
Requirements for the 2008 8Hour Ozone National Ambient
Air Quality Standards.
State effective
date
*
10/31/2011
3. Section 52.522 is amended by
designating the existing paragraph as
paragraph (a) and adding paragraph (b)
to read as follows:
■
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§ 52.522
Approval status.
(a) * * *
(b) Disapproval. Submittal from the
State of Florida, through the Florida
Department of Environmental Protection
(FDEP) on October 31, 2011, to address
the Clean Air Act (CAA) sections
110(a)(2)(C), 110(a)(2)(D)(i)(II), and
110(a)(2)(J) for the 2008 8-hour Ozone
National Ambient Air Quality Standards
related to prevention of significant
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EPA approval
date
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11/1/13
Federal Register
notice
*
*
*
*
[Insert citation of pub- With the exception of section 110(a)(2)(D)(i)(I) conlication].
cerning
interstate
transport;
section
110(a)(2)(D)(i)(II) concerning visibility requirements; and the portions of sections 110(a)(2)(C),
prong 3 of 110(a)(2)(D)(i), and 110(a)(2)(J) related to the regulation of GHG emissions, which
are being disapproved.
deterioration (PSD) requirements for the
regulation of greenhouse gas emissions.
EPA is disapproving FDEP’s submittal
with respect to the PSD requirements of
CAA sections 110(a)(2)(C),
110(a)(2)(D)(i)(II), and 110(a)(2)(J) for the
2008 8-hour Ozone National Ambient
Air Quality Standards related to PSD
requirements for the regulation of
greenhouse gas emissions.
[FR Doc. 2013–25985 Filed 10–31–13; 8:45 am]
BILLING CODE 6560–50–P
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Explanation
ENVIRONMENTAL PROTECTION
AGENCY
40 CFR Part 180
[EPA–HQ–OPP–2013–0165; FRL–9901–95]
D-Glucopyranose, oligomeric, decyl
octyl glycosides; Exemption from the
Requirement of a Tolerance
Environmental Protection
Agency (EPA).
ACTION: Final rule.
AGENCY:
This regulation establishes an
exemption from the requirement of a
SUMMARY:
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tolerance for residues of DGlucopyranose, oligomeric, decyl octyl
glycosides when used as an inert
ingredient (surfactant) in antimicrobial
formulations (food-contact surface
sanitizing solutions) applied to foodcontact surfaces in public eating places,
dairy-processing equipment, and foodprocessing equipment and utensils.
Lewis & Harrison, on behalf of BASF
Corporation, submitted a petition to
EPA under the Federal Food, Drug, and
Cosmetic Act (FFDCA), requesting
establishment of an exemption from the
requirement of a tolerance. This
regulation eliminates the need to
establish a maximum permissible level
for residues of D-Glucopyranose,
oligomeric, decyl octyl glycosides.
DATES: This regulation is effective
November 1, 2013. Objections and
requests for hearings must be received
on or before December 31, 2013, and
must be filed in accordance with the
instructions provided in 40 CFR part
178 (see also Unit I.C. of the
SUPPLEMENTARY INFORMATION).
ADDRESSES: The docket for this action,
identified by docket identification (ID)
number EPA–HQ–OPP–2013–0165, is
available at https://www.regulations.gov
or at the Office of Pesticide Programs
Regulatory Public Docket (OPP Docket)
in the Environmental Protection Agency
Docket Center (EPA/DC), EPA West
Bldg., Rm. 3334, 1301 Constitution Ave.
NW., Washington, DC 20460–0001. The
Public Reading Room is open from 8:30
a.m. to 4:30 p.m., Monday through
Friday, excluding legal holidays. The
telephone number for the Public
Reading Room is (202) 566–1744, and
the telephone number for the OPP
Docket is (703) 305–5805. Please review
the visitor instructions and additional
information about the docket available
at https://www.epa.gov/dockets.
FOR FURTHER INFORMATION CONTACT: Lois
Rossi, Registration Division (7505P),
Office of Pesticide Programs,
Environmental Protection Agency, 1200
Pennsylvania Ave. NW., Washington,
DC 20460–0001; telephone number:
(703) 305–7090; email address:
RDFRNotices@epa.gov.
SUPPLEMENTARY INFORMATION:
I. General Information
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A. Does this action apply to me?
You may be potentially affected by
this action if you are an agricultural
producer, food manufacturer, or
pesticide manufacturer. The following
list of North American Industrial
Classification System (NAICS) codes is
not intended to be exhaustive, but rather
provides a guide to help readers
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determine whether this document
applies to them. Potentially affected
entities may include:
• Crop production (NAICS code 111).
• Animal production (NAICS code
112).
• Food manufacturing (NAICS code
311).
• Pesticide manufacturing (NAICS
code 32532).
delivery of boxed information, please
follow the instructions at https://
www.epa.gov/dockets/contacts.html.
Additional instructions on commenting
or visiting the docket, along with more
information about dockets generally, is
available at https://www.epa.gov/
dockets.
B. How can I get electronic access to
other related information?
You may access a frequently updated
electronic version of 40 CFR part 180
through the Government Printing
Office’s e-CFR site at https://
www.ecfr.gov/cgi-bin/textidx?&c=ecfr&tpl=/ecfrbrowse/Title40/
40tab_02.tpl.
In the Federal Register of June 5, 2013
(78 FR 33785) (FRL–9386–2), EPA
issued a document pursuant to FFDCA
section 408, 21 U.S.C. 346a, announcing
the filing of a pesticide petition (PP IN–
10545) by Lewis & Harrison, LLC, 122
C St. NW., Suite 740, Washington, DC
20001 on behalf of BASF Corporation,
100 Park Ave., Florham Park, NJ 07932.
The petition requested that 40 CFR
180.940(a) be amended by establishing
an exemption from the requirement of a
tolerance for residues of alkyl (C8-C10)
polyglucosides (CAS Reg. No. 68515–
73–1) when used as an inert ingredient
(surfactant) in antimicrobial
formulations (i.e., food contact surface
sanitizing solutions) applied to foodcontact surfaces in public eating places,
dairy-processing equipment, and foodprocessing equipment and utensils.
That document referenced a summary
of the petition prepared by Lewis &
Harrison, LLC, on behalf of BASF
Corporation, the petitioner, which is
available in the docket, https://
www.regulations.gov. There were no
comments received in response to the
notice of filing.
EPA is establishing a tolerance using
a different chemical name than the one
requested by the petitioner for the
reasons discussed in Unit V.B.
C. How can I file an objection or hearing
request?
Under FFDCA section 408(g), 21
U.S.C. 346a, any person may file an
objection to any aspect of this regulation
and may also request a hearing on those
objections. You must file your objection
or request a hearing on this regulation
in accordance with the instructions
provided in 40 CFR part 178. To ensure
proper receipt by EPA, you must
identify docket ID number EPA–HQ–
OPP–2013–0165 in the subject line on
the first page of your submission. All
objections and requests for a hearing
must be in writing, and must be
received by the Hearing Clerk on or
before December 31, 2013. Addresses for
mail and hand delivery of objections
and hearing requests are provided in 40
CFR 178.25(b).
In addition to filing an objection or
hearing request with the Hearing Clerk
as described in 40 CFR part 178, please
submit a copy of the filing (excluding
any Confidential Business Information
(CBI)) for inclusion in the public docket.
Information not marked confidential
pursuant to 40 CFR part 2 may be
disclosed publicly by EPA without prior
notice. Submit the non-CBI copy of your
objection or hearing request, identified
by docket ID number EPA–HQ–OPP–
2013–0165, by one of the following
methods:
• Federal eRulemaking Portal: https://
www.regulations.gov. Follow the online
instructions for submitting comments.
Do not submit electronically any
information you consider to be CBI or
other information whose disclosure is
restricted by statute.
• Mail: OPP Docket, Environmental
Protection Agency Docket Center (EPA/
DC), (28221T), 1200 Pennsylvania Ave.
NW., Washington, DC 20460–0001.
• Hand Delivery: To make special
arrangements for hand delivery or
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II. Petition for Exemption
III. Inert Ingredient Definition
Inert ingredients are all ingredients
that are not active ingredients as defined
in 40 CFR 153.125 and include, but are
not limited to, the following types of
ingredients (except when they have a
pesticidal efficacy of their own):
Solvents such as alcohols and
hydrocarbons; surfactants such as
polyoxyethylene polymers and fatty
acids; carriers such as clay and
diatomaceous earth; thickeners such as
carrageenan and modified cellulose;
wetting, spreading, and dispersing
agents; propellants in aerosol
dispensers; microencapsulating agents;
and emulsifiers. The term ‘‘inert’’ is not
intended to imply nontoxicity; the
ingredient may or may not be
chemically active. Generally, EPA has
exempted inert ingredients from the
requirement of a tolerance based on the
low toxicity of the individual inert
ingredients.
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IV. Aggregate Risk Assessment and
Determination of Safety
Section 408(c)(2)(A)(i) of FFDCA
allows EPA to establish an exemption
from the requirement for a tolerance (the
legal limit for a pesticide chemical
residue in or on a food) only if EPA
determines that the tolerance is ‘‘safe.’’
Section 408(b)(2)(A)(ii) of FFDCA
defines ‘‘safe’’ to mean that ‘‘there is a
reasonable certainty that no harm will
result from aggregate exposure to the
pesticide chemical residue, including
all anticipated dietary exposures and all
other exposures for which there is
reliable information.’’ This includes
exposure through drinking water and in
residential settings, but does not include
occupational exposure. Section
408(b)(2)(C) of FFDCA requires EPA to
give special consideration to exposure
of infants and children to the pesticide
chemical residue in establishing a
tolerance and to ‘‘ensure that there is a
reasonable certainty that no harm will
result to infants and children from
aggregate exposure to the pesticide
chemical residue. . . .’’
EPA establishes exemptions from the
requirement of a tolerance only in those
cases where it can be clearly
demonstrated that the risks from
aggregate exposure to pesticide
chemical residues under reasonably
foreseeable circumstances will pose no
appreciable risks to human health. In
order to determine the risks from
aggregate exposure to pesticide inert
ingredients, the Agency considers the
toxicity of the inert in conjunction with
possible exposure to residues of the
inert ingredient through food, drinking
water, and through other exposures that
occur as a result of pesticide use in
residential settings. If EPA is able to
determine that a finite tolerance is not
necessary to ensure that there is a
reasonable certainty that no harm will
result from aggregate exposure to the
inert ingredient, an exemption from the
requirement of a tolerance may be
established.
Consistent with FFDCA section
408(c)(2)(A), and the factors specified in
FFDCA section 408(c)(2)(B), EPA has
reviewed the available scientific data
and other relevant information in
support of this action. EPA has
sufficient data to assess the hazards of
and to make a determination on
aggregate exposure for DGlucopyranose, oligomeric, decyl octyl
glycosides including exposure resulting
from the exemption established by this
action. EPA’s assessment of exposures
and risks associated with DGlucopyranose, oligomeric, decyl octyl
glycosides follows.
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A. Toxicological Profile
EPA has evaluated the available
toxicity data and considered their
validity, completeness, and reliability as
well as the relationship of the results of
the studies to human risk. EPA has also
considered available information
concerning the variability of the
sensitivities of major identifiable
subgroups of consumers, including
infants and children. Specific
information on the studies received and
the nature of the adverse effects caused
by D-Glucopyranose, oligomeric, decyl
octyl glycosides as well as the noobserved-adverse-effect-level (NOAEL)
and the lowest-observed-adverse-effectlevel (LOAEL) from the toxicity studies
are discussed in this unit.
In order to make a safety finding on
D-Glucopyranose, oligomeric, decyl
octyl glycosides, EPA used data on the
chemical itself and structurally similar
chemicals—alkyl (C12-C14)
polyglycosides and alkyl (C10-C16)
polyglycosides (also known as Dglycopyranose, oligomeric, C10-C16alkyl glycosides). These three chemicals
differ from one another only in the
length of the alkyl chain. Given these
structural similarities, these chemicals
are expected to have similar
toxicological characteristics. Therefore,
data on alkyl (C10-C16) polyglycosides
and alkyl (C12-C14) polyglycosides have
been used to make a safety finding on
alkyl (C8-C10) polyglycosides. For ease of
reading, alkyl polyglycosides will be
collectively known throughout the
document as ‘‘APG’’ with the specific
carbon chain length identified as ‘‘(CxCx),’’ when appropriate.
Acute studies indicate low acute oral
and dermal toxicity. Studies using APG
(C8-C10) did not show evidence of eye or
skin irritation. Repeat dose studies for
APGs include a 90-day gavage study, a
14-day dermal, a reproduction study,
and a developmental study. In the 90day rat oral (gavage) study APG (C12-C14)
was administered at dose levels of 0,
250, 500, or 1,000 milligram/kilogram/
day (mg/kg/day) for 5 days/week. There
were no treatment-related adverse
effects on body weight, body weight
gain, food consumption, hematological
or clinical chemistry parameters, or
organ weights. Adverse treatmentrelated effects were limited to irritation
in the forestomach in both males and
females receiving 500 or 1,000 mg/kg/
day. Effects were reversible following
the cessation of treatment, but not
reversible during treatment. Because
humans do not have a forestomach that
serves as a storage reservoir as in
rodents, the effects seen in the rat
forestomach are likely to be significantly
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more severe than what would be
expected from the compound in the
glandular stomach in humans and
subsequently, have less relevance to
humans. Therefore, the EPA determined
the systemic oral toxicity NOAEL was
1,000 mg/kg/day. A LOAEL was not
determined.
A 14-day dermal study on APGs (C8C10) was conducted on rabbits (New
Zealand white) at doses of 0, 60, 180,
540, 1,500, and 3,000 mg/kg/day. While
skin irritation was observed at doses
above 180 mg/kg/day and changes in
hematological and clinical parameters
and testicular degeneration were
observed at the dose levels of 1,500 and
3,000 mg/kg/day, these effects are likely
attributable to stress and inflammation
due to the severe irritation caused by
the test substance and therefore a
NOAEL for systemic effects was not
established.
A 1-generation reproductive screening
study on APG (C10-C16) was conducted
on male and female rats following daily
administration (gavage) of 100, 300, and
1,000 mg/kg/day. No effects indicative
of general toxicity were observed in
parental animals. Relative and absolute
weights of testes, epididymides, and
seminal vesicles did not differ between
test and control animals. No
reproductive parameters were affected
including mean litter weights, mean
pup weights, sex ratios, and gestation
periods. Pre-weaning clinical signs
showed no treatment-related effects in
pups, nor did necropsy reveal any
effects in decedent or Fl pups.
Macroscopic examination revealed no
difference between treated and control
animals. A NOAEL of 1,000 mg/kg/day
for reproductive effects can be deduced.
In a rat developmental toxicity study,
APG (C12-C14) was administered by
gavage at dose levels of 0, 100, 300, and
1,000 mg/kg/day on gestation days 6 to
15. No treatment-related maternal
deaths; clinical signs; or decreases in
mean body weight, weight gain,
corrected weight gain, or gross lesions
were observed in this study. In addition,
there were no treatment-related
developmental effects (e.g., external
abnormalities, visceral abnormalities, or
skeletal malformations/variations).
Therefore, the developmental and
maternal NOAEL is 1,000 mg/kg/day. A
LOAEL was not determined.
No immunotoxicity or neurotoxicity
studies are available in the database;
however, APGs (C8-C10) are unlikely to
produce neurotoxicity or evoke
immunological response given the lack
of any toxicity, including any
immunotoxicity or neurotoxicity, at
high doses (1,000 mg/kg/day).
Mutagenicity studies on various chain
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lengths of APGs were negative
indicating that APGs are not likely to be
mutagenic. No carcinogenicity studies
are available on APGs; however, APGs
are not expected to be carcinogenic
based on lack of mutagenicity, lack of
any systemic toxicity at doses up to and
including 1,000 mg/kg/day, and the
rapid metabolism of these chemicals to
sugars and alcohols and excretion from
the body.
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B. Toxicological Points of Departure/
Levels of Concern
Metabolism studies on structurally
related chemicals indicate that the body
can effectively metabolize Dglucopyranose, oligomeric, C10-C16-alkyl
glycosides to water-soluble substances
(predominantly sugar and various
alcohols) that are readily excreted from
the body. No adverse effects were seen
any of the repeat dose studies
conducted via the oral route of exposure
at or above the limit dose. No endpoint
of concern was identified based on the
available studies in the database.
C. Exposure Assessment
Because no endpoint of concern was
identified based upon available data, a
qualitative risk assessment was
conducted.
1. Dietary exposure from food and
feed uses. In evaluating dietary
exposure to D-Glucopyranose,
oligomeric, decyl octyl glycosides, EPA
considered exposure under the
proposed exemption from the
requirement of a tolerance. For purposes
of this action, EPA qualitatively
assessed dietary exposures from DGlucopyranose, oligomeric, decyl octyl
glycosides as follows:
Dietary exposure could potentially
occur from consuming foods directly
treated with pesticide products
containing the inert ingredient. In
addition, dietary exposure to APGs
could occur as a result of contact with
surfaces treated with antimicrobial
formulations containing the inert
ingredient, including food-contact
surfaces in public eating places, dairyprocessing equipment, or foodprocessing equipment and utensils.
Dietary exposure may also come from
consuming animal products from
animals exposed to the inert ingredient
via pesticide application or from eating
feed treated with pesticide products
containing the inert ingredient.
2. Dietary exposure from drinking
water. Dietary exposure from drinking
water to D-Glucopyranose, oligomeric,
decyl octyl glycosides can occur by
drinking water that has been
contaminated by contact with pesticide
treated areas, such as countertops. Since
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an endpoint for risk assessment was not
identified, a quantitative dietary
exposure assessment from drinking
water for D-Glucopyranose, oligomeric,
decyl octyl glycosides was not
conducted.
3. From non-dietary exposure. The
term ‘‘residential exposure’’ is used in
this document to refer to nonoccupational, non-dietary exposure
(e.g., textiles (clothing and diapers),
carpets, swimming pools, and hard
surface disinfection on walls, floors,
tables). APGs are used in laundry
detergents, hard surface and household
cleaners, as rinse aids in dishwashers
and in personal care products. Nondietary exposure could result from both
pesticidal and non-pesticidal uses.
4. Cumulative effects from substances
with a common mechanism of toxicity.
Section 408(b)(2)(D)(v) of FFDCA
requires that, when considering whether
to establish, modify, or revoke a
tolerance, the Agency consider
‘‘available information’’ concerning the
cumulative effects of a particular
pesticide’s residues and ‘‘other
substances that have a common
mechanism of toxicity.’’
EPA has not found D-Glucopyranose,
oligomeric, decyl octyl glycosides to
share a common mechanism of toxicity
with any other substances, and DGlucopyranose, oligomeric, decyl octyl
glycosides does not appear to produce a
toxic metabolite produced by other
substances. For the purposes of this
tolerance action, therefore, EPA has
assumed that D-Glucopyranose,
oligomeric, decyl octyl glycosides does
not have a common mechanism of
toxicity with other substances. For
information regarding EPA’s efforts to
determine which chemicals have a
common mechanism of toxicity and to
evaluate the cumulative effects of such
chemicals, see EPA’s Web site at https://
www.epa.gov/pesticides/cumulative.
D. Safety Factor for Infants and
Children
As part of its qualitative assessment,
the Agency did not use safety factors for
assessing risk, and no additional safety
factor is needed for assessing risk to
infants and children. The toxicity
database for APGs contains several
acute studies, a 90-day oral toxicity
study, a 14-dermal study, a
developmental toxicity study, and a
reproductive screening toxicity study.
No hazard was identified based on those
studies. The toxicity database does not
contain a carcinogenicity study, an
immunotoxicity study, or a
neurotoxicity study, but for the reasons
stated in Unit IV.A., the Agency has
concluded that there are no concerns for
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carcinogenicity, immunotoxicity, or
neurotoxicity for this chemical. No
developmental or reproductive effects
were seen in the available studies. Thus,
there is no residual uncertainty
regarding prenatal and/or postnatal
toxicity of D-Glucopyrnose, oligomeric,
decyl octyl glycosides.
Based on this information, there is no
concern at this time for increased
sensitivity to infants and children to DGlucopyrnose, oligomeric, decyl octyl
glycosides when used as an inert
ingredient in antimicrobial formulations
applied to food-contact surfaces in
public eating places, dairy-processing
equipment, and food-processing
equipment and utensils.
E. Aggregate Risks and Determination of
Safety
Taking into consideration all available
information on D-Glucopyranose,
oligomeric, decyl octyl glycosides, EPA
has determined that there is a
reasonable certainty that no harm to any
population subgroup will result from
aggregate exposure to D-Glucopyranose,
oligomeric, decyl octyl glycosides under
reasonably foreseeable circumstances.
Therefore, the establishment of an
exemption from tolerance under 40 CFR
180.940(a) for residues of DGlucopyranose, oligomeric, decyl octyl
glycosides when used as an inert
ingredient in in antimicrobial foodcontact surface sanitizing solutions is
safe under FFDCA section 408.
V. Other Considerations
A. Analytical Enforcement Methodology
An analytical method is not required
for enforcement purposes since the
Agency is establishing an exemption
from the requirement of a tolerance
without any numerical limitation.
B. Revisions to Petitioned-For
Tolerances
Alkyl (C8-C10) polyglycosides and DGlucopyranose, oligomeric, decyl octyl
glycosides are alternate names for the
chemical with the CAS Reg. No. 68515–
73–1 and therefore, represent the same
chemical. EPA is using the latter name
because it is the one used in the
Chemical Abstract (CA) Index and the
one EPA has used to establish other
exemptions from the requirement of
tolerance for this chemical.
VI. Conclusions
Therefore, an exemption from the
requirement of a tolerance is established
under 40 CFR 180.940(a) for DGlucopyranose, oligomeric, decyl octyl
glycosides (CAS Reg. No. 68515–73–1)
when used as an inert ingredient
(surfactant) in antimicrobial
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formulations (i.e., food contact surface
sanitizing solutions) applied to foodcontact surfaces in public eating places,
dairy-processing equipment, and foodprocessing equipment and utensils.
VII. Statutory and Executive Order
Reviews
This final rule establishes an
exemption from the requirement of a
tolerance under FFDCA section 408(d)
in response to a petition submitted to
the Agency. The Office of Management
and Budget (OMB) has exempted these
types of actions from review under
Executive Order 12866, entitled
‘‘Regulatory Planning and Review’’ (58
FR 51735, October 4, 1993). Because
this final rule has been exempted from
review under Executive Order 12866,
this final rule is not subject to Executive
Order 13211, entitled ‘‘Actions
Concerning Regulations That
Significantly Affect Energy Supply,
Distribution, or Use’’ (66 FR 28355, May
22, 2001) or Executive Order 13045,
entitled ‘‘Protection of Children from
Environmental Health Risks and Safety
Risks’’ (62 FR 19885, April 23, 1997).
This final rule does not contain any
information collections subject to OMB
approval under the Paperwork
Reduction Act (PRA) (44 U.S.C. 3501 et
seq.), nor does it require any special
considerations under Executive Order
12898, entitled ‘‘Federal Actions to
Address Environmental Justice in
Minority Populations and Low-Income
Populations’’ (59 FR 7629, February 16,
1994).
Since tolerances and exemptions that
are established on the basis of a petition
under FFDCA section 408(d), such as
the exemption in this final rule, do not
require the issuance of a proposed rule,
the requirements of the Regulatory
Flexibility Act (RFA) (5 U.S.C. 601 et
seq.), do not apply.
This final rule directly regulates
growers, food processors, food handlers,
and food retailers, not States or tribes,
nor does this action alter the
relationships or distribution of power
and responsibilities established by
Congress in the preemption provisions
of FFDCA section 408(n)(4). As such,
the Agency has determined that this
action will not have a substantial direct
effect on States or tribal governments,
on the relationship between the national
government and the States or tribal
governments, or on the distribution of
power and responsibilities among the
various levels of government or between
the Federal Government and Indian
Tribes. Thus, the Agency has
determined that Executive Order 13132,
entitled ‘‘Federalism’’ (64 FR 43255,
August 10, 1999) and Executive Order
13175, entitled ‘‘Consultation and
Coordination with Indian Tribal
Governments’’ (65 FR 67249, November
9, 2000) do not apply to this final rule.
In addition, this final rule does not
impose any enforceable duty or contain
any unfunded mandate as described
under Title II of the Unfunded Mandates
Reform Act of 1995 (UMRA) (2 U.S.C.
1501 et seq.).
This action does not involve any
technical standards that would require
Agency consideration of voluntary
consensus standards pursuant to section
12(d) of the National Technology
Transfer and Advancement Act of 1995
(NTTAA) (15 U.S.C. 272 note).
VIII. Congressional Review Act
Pursuant to the Congressional Review
Act (5 U.S.C. 801 et seq.), EPA will
submit a report containing this rule and
other required information to the U.S.
Senate, the U.S. House of
Representatives, and the Comptroller
General of the United States prior to
publication of the rule in the Federal
Register. This action is not a ‘‘major
rule’’ as defined by 5 U.S.C. 804(2).
List of Subjects in 40 CFR Part 180
Environmental protection,
Administrative practice and procedure,
Agricultural commodities, Pesticides
and pests, Reporting and recordkeeping
requirements.
Dated: October 22, 2013.
Lois Rossi,
Director, Registration Division, Office of
Pesticide Programs.
Therefore, 40 CFR chapter I is
amended as follows:
PART 180—[AMENDED]
1. The authority citation for part 180
continues to read as follows:
■
Authority: 21 U.S.C. 321(q), 346a and 371.
2. In § 180.940, add alphabetically the
following entry to the table in paragraph
(a) to read as follows:
■
§ 180.940 Tolerance exemptions for active
and inert ingredients for use in
antimicrobial formulations (Food-contact
surface sanitizing solutions).
*
*
*
(a) * * *
Pesticide chemical
*
*
*
*
*
*
*
BILLING CODE 6560–50–P
ENVIRONMENTAL PROTECTION
AGENCY
ehiers on DSK2VPTVN1PROD with RULES
40 CFR Part 180
[EPA–HQ–OPP–2012–0589; FRL–9401–8]
Fomesafen; Pesticide Tolerances
Environmental Protection
Agency (EPA).
ACTION: Final rule.
AGENCY:
VerDate Mar<15>2010
15:07 Oct 31, 2013
*
*
This regulation establishes
tolerances for residues of fomesafen in
or on multiple commodities which are
identified and discussed later in this
document. Interregional Research
Project Number 4 (IR–4) requested these
tolerances under the Federal Food,
Drug, and Cosmetic Act (FFDCA).
DATES: This regulation is effective
November 1, 2013. Objections and
requests for hearings must be received
on or before December 31, 2013, and
must be filed in accordance with the
instructions provided in 40 CFR part
178 (see also Unit I.C. of the
SUPPLEMENTARY INFORMATION).
SUMMARY:
[FR Doc. 2013–26241 Filed 10–31–13; 8:45 am]
Jkt 232001
PO 00000
Frm 00051
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CAS Reg. No.
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D-Glucopyranose, oligomeric, decyl octyl glycosides ...........................................................................................
*
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Fmt 4700
Sfmt 4700
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68515–73–1
*
Limits
*
None
*
The docket for this action,
identified by docket identification (ID)
number EPA–HQ–OPP–2012–0589, is
available at https://www.regulations.gov
or at the Office of Pesticide Programs
Regulatory Public Docket (OPP Docket)
in the Environmental Protection Agency
Docket Center (EPA/DC), EPA West
Bldg., Rm. 3334, 1301 Constitution Ave.
NW., Washington, DC 20460–0001. The
Public Reading Room is open from 8:30
a.m. to 4:30 p.m., Monday through
Friday, excluding legal holidays. The
telephone number for the Public
Reading Room is (202) 566–1744, and
the telephone number for the OPP
ADDRESSES:
E:\FR\FM\01NOR1.SGM
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Agencies
[Federal Register Volume 78, Number 212 (Friday, November 1, 2013)]
[Rules and Regulations]
[Pages 65561-65565]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2013-26241]
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
40 CFR Part 180
[EPA-HQ-OPP-2013-0165; FRL-9901-95]
D-Glucopyranose, oligomeric, decyl octyl glycosides; Exemption
from the Requirement of a Tolerance
AGENCY: Environmental Protection Agency (EPA).
ACTION: Final rule.
-----------------------------------------------------------------------
SUMMARY: This regulation establishes an exemption from the requirement
of a
[[Page 65562]]
tolerance for residues of D-Glucopyranose, oligomeric, decyl octyl
glycosides when used as an inert ingredient (surfactant) in
antimicrobial formulations (food-contact surface sanitizing solutions)
applied to food-contact surfaces in public eating places, dairy-
processing equipment, and food-processing equipment and utensils. Lewis
& Harrison, on behalf of BASF Corporation, submitted a petition to EPA
under the Federal Food, Drug, and Cosmetic Act (FFDCA), requesting
establishment of an exemption from the requirement of a tolerance. This
regulation eliminates the need to establish a maximum permissible level
for residues of D-Glucopyranose, oligomeric, decyl octyl glycosides.
DATES: This regulation is effective November 1, 2013. Objections and
requests for hearings must be received on or before December 31, 2013,
and must be filed in accordance with the instructions provided in 40
CFR part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION).
ADDRESSES: The docket for this action, identified by docket
identification (ID) number EPA-HQ-OPP-2013-0165, is available at https://www.regulations.gov or at the Office of Pesticide Programs Regulatory
Public Docket (OPP Docket) in the Environmental Protection Agency
Docket Center (EPA/DC), EPA West Bldg., Rm. 3334, 1301 Constitution
Ave. NW., Washington, DC 20460-0001. The Public Reading Room is open
from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal
holidays. The telephone number for the Public Reading Room is (202)
566-1744, and the telephone number for the OPP Docket is (703) 305-
5805. Please review the visitor instructions and additional information
about the docket available at https://www.epa.gov/dockets.
FOR FURTHER INFORMATION CONTACT: Lois Rossi, Registration Division
(7505P), Office of Pesticide Programs, Environmental Protection Agency,
1200 Pennsylvania Ave. NW., Washington, DC 20460-0001; telephone
number: (703) 305-7090; email address: RDFRNotices@epa.gov.
SUPPLEMENTARY INFORMATION:
I. General Information
A. Does this action apply to me?
You may be potentially affected by this action if you are an
agricultural producer, food manufacturer, or pesticide manufacturer.
The following list of North American Industrial Classification System
(NAICS) codes is not intended to be exhaustive, but rather provides a
guide to help readers determine whether this document applies to them.
Potentially affected entities may include:
Crop production (NAICS code 111).
Animal production (NAICS code 112).
Food manufacturing (NAICS code 311).
Pesticide manufacturing (NAICS code 32532).
B. How can I get electronic access to other related information?
You may access a frequently updated electronic version of 40 CFR
part 180 through the Government Printing Office's e-CFR site at https://www.ecfr.gov/cgi-bin/text-idx?&c=ecfr&tpl=/ecfrbrowse/Title40/40tab_02.tpl.
C. How can I file an objection or hearing request?
Under FFDCA section 408(g), 21 U.S.C. 346a, any person may file an
objection to any aspect of this regulation and may also request a
hearing on those objections. You must file your objection or request a
hearing on this regulation in accordance with the instructions provided
in 40 CFR part 178. To ensure proper receipt by EPA, you must identify
docket ID number EPA-HQ-OPP-2013-0165 in the subject line on the first
page of your submission. All objections and requests for a hearing must
be in writing, and must be received by the Hearing Clerk on or before
December 31, 2013. Addresses for mail and hand delivery of objections
and hearing requests are provided in 40 CFR 178.25(b).
In addition to filing an objection or hearing request with the
Hearing Clerk as described in 40 CFR part 178, please submit a copy of
the filing (excluding any Confidential Business Information (CBI)) for
inclusion in the public docket. Information not marked confidential
pursuant to 40 CFR part 2 may be disclosed publicly by EPA without
prior notice. Submit the non-CBI copy of your objection or hearing
request, identified by docket ID number EPA-HQ-OPP-2013-0165, by one of
the following methods:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the online instructions for submitting comments. Do not submit
electronically any information you consider to be CBI or other
information whose disclosure is restricted by statute.
Mail: OPP Docket, Environmental Protection Agency Docket
Center (EPA/DC), (28221T), 1200 Pennsylvania Ave. NW., Washington, DC
20460-0001.
Hand Delivery: To make special arrangements for hand
delivery or delivery of boxed information, please follow the
instructions at https://www.epa.gov/dockets/contacts.html. Additional
instructions on commenting or visiting the docket, along with more
information about dockets generally, is available at https://www.epa.gov/dockets.
II. Petition for Exemption
In the Federal Register of June 5, 2013 (78 FR 33785) (FRL-9386-2),
EPA issued a document pursuant to FFDCA section 408, 21 U.S.C. 346a,
announcing the filing of a pesticide petition (PP IN-10545) by Lewis &
Harrison, LLC, 122 C St. NW., Suite 740, Washington, DC 20001 on behalf
of BASF Corporation, 100 Park Ave., Florham Park, NJ 07932. The
petition requested that 40 CFR 180.940(a) be amended by establishing an
exemption from the requirement of a tolerance for residues of alkyl
(C8-C10) polyglucosides (CAS Reg. No. 68515-73-1)
when used as an inert ingredient (surfactant) in antimicrobial
formulations (i.e., food contact surface sanitizing solutions) applied
to food-contact surfaces in public eating places, dairy-processing
equipment, and food-processing equipment and utensils.
That document referenced a summary of the petition prepared by
Lewis & Harrison, LLC, on behalf of BASF Corporation, the petitioner,
which is available in the docket, https://www.regulations.gov. There
were no comments received in response to the notice of filing.
EPA is establishing a tolerance using a different chemical name
than the one requested by the petitioner for the reasons discussed in
Unit V.B.
III. Inert Ingredient Definition
Inert ingredients are all ingredients that are not active
ingredients as defined in 40 CFR 153.125 and include, but are not
limited to, the following types of ingredients (except when they have a
pesticidal efficacy of their own): Solvents such as alcohols and
hydrocarbons; surfactants such as polyoxyethylene polymers and fatty
acids; carriers such as clay and diatomaceous earth; thickeners such as
carrageenan and modified cellulose; wetting, spreading, and dispersing
agents; propellants in aerosol dispensers; microencapsulating agents;
and emulsifiers. The term ``inert'' is not intended to imply
nontoxicity; the ingredient may or may not be chemically active.
Generally, EPA has exempted inert ingredients from the requirement of a
tolerance based on the low toxicity of the individual inert
ingredients.
[[Page 65563]]
IV. Aggregate Risk Assessment and Determination of Safety
Section 408(c)(2)(A)(i) of FFDCA allows EPA to establish an
exemption from the requirement for a tolerance (the legal limit for a
pesticide chemical residue in or on a food) only if EPA determines that
the tolerance is ``safe.'' Section 408(b)(2)(A)(ii) of FFDCA defines
``safe'' to mean that ``there is a reasonable certainty that no harm
will result from aggregate exposure to the pesticide chemical residue,
including all anticipated dietary exposures and all other exposures for
which there is reliable information.'' This includes exposure through
drinking water and in residential settings, but does not include
occupational exposure. Section 408(b)(2)(C) of FFDCA requires EPA to
give special consideration to exposure of infants and children to the
pesticide chemical residue in establishing a tolerance and to ``ensure
that there is a reasonable certainty that no harm will result to
infants and children from aggregate exposure to the pesticide chemical
residue. . . .''
EPA establishes exemptions from the requirement of a tolerance only
in those cases where it can be clearly demonstrated that the risks from
aggregate exposure to pesticide chemical residues under reasonably
foreseeable circumstances will pose no appreciable risks to human
health. In order to determine the risks from aggregate exposure to
pesticide inert ingredients, the Agency considers the toxicity of the
inert in conjunction with possible exposure to residues of the inert
ingredient through food, drinking water, and through other exposures
that occur as a result of pesticide use in residential settings. If EPA
is able to determine that a finite tolerance is not necessary to ensure
that there is a reasonable certainty that no harm will result from
aggregate exposure to the inert ingredient, an exemption from the
requirement of a tolerance may be established.
Consistent with FFDCA section 408(c)(2)(A), and the factors
specified in FFDCA section 408(c)(2)(B), EPA has reviewed the available
scientific data and other relevant information in support of this
action. EPA has sufficient data to assess the hazards of and to make a
determination on aggregate exposure for D-Glucopyranose, oligomeric,
decyl octyl glycosides including exposure resulting from the exemption
established by this action. EPA's assessment of exposures and risks
associated with D-Glucopyranose, oligomeric, decyl octyl glycosides
follows.
A. Toxicological Profile
EPA has evaluated the available toxicity data and considered their
validity, completeness, and reliability as well as the relationship of
the results of the studies to human risk. EPA has also considered
available information concerning the variability of the sensitivities
of major identifiable subgroups of consumers, including infants and
children. Specific information on the studies received and the nature
of the adverse effects caused by D-Glucopyranose, oligomeric, decyl
octyl glycosides as well as the no-observed-adverse-effect-level
(NOAEL) and the lowest-observed-adverse-effect-level (LOAEL) from the
toxicity studies are discussed in this unit.
In order to make a safety finding on D-Glucopyranose, oligomeric,
decyl octyl glycosides, EPA used data on the chemical itself and
structurally similar chemicals--alkyl (C12-C14)
polyglycosides and alkyl (C10-C16) polyglycosides
(also known as D-glycopyranose, oligomeric, C10-
C16- alkyl glycosides). These three chemicals differ from
one another only in the length of the alkyl chain. Given these
structural similarities, these chemicals are expected to have similar
toxicological characteristics. Therefore, data on alkyl
(C10-C16) polyglycosides and alkyl
(C12-C14) polyglycosides have been used to make a
safety finding on alkyl (C8-C10) polyglycosides.
For ease of reading, alkyl polyglycosides will be collectively known
throughout the document as ``APG'' with the specific carbon chain
length identified as ``(Cx-Cx),'' when
appropriate.
Acute studies indicate low acute oral and dermal toxicity. Studies
using APG (C8-C10) did not show evidence of eye
or skin irritation. Repeat dose studies for APGs include a 90-day
gavage study, a 14-day dermal, a reproduction study, and a
developmental study. In the 90-day rat oral (gavage) study APG
(C12-C14) was administered at dose levels of 0,
250, 500, or 1,000 milligram/kilogram/day (mg/kg/day) for 5 days/week.
There were no treatment-related adverse effects on body weight, body
weight gain, food consumption, hematological or clinical chemistry
parameters, or organ weights. Adverse treatment-related effects were
limited to irritation in the forestomach in both males and females
receiving 500 or 1,000 mg/kg/day. Effects were reversible following the
cessation of treatment, but not reversible during treatment. Because
humans do not have a forestomach that serves as a storage reservoir as
in rodents, the effects seen in the rat forestomach are likely to be
significantly more severe than what would be expected from the compound
in the glandular stomach in humans and subsequently, have less
relevance to humans. Therefore, the EPA determined the systemic oral
toxicity NOAEL was 1,000 mg/kg/day. A LOAEL was not determined.
A 14-day dermal study on APGs (C8-C10) was
conducted on rabbits (New Zealand white) at doses of 0, 60, 180, 540,
1,500, and 3,000 mg/kg/day. While skin irritation was observed at doses
above 180 mg/kg/day and changes in hematological and clinical
parameters and testicular degeneration were observed at the dose levels
of 1,500 and 3,000 mg/kg/day, these effects are likely attributable to
stress and inflammation due to the severe irritation caused by the test
substance and therefore a NOAEL for systemic effects was not
established.
A 1-generation reproductive screening study on APG (C10-
C16) was conducted on male and female rats following daily
administration (gavage) of 100, 300, and 1,000 mg/kg/day. No effects
indicative of general toxicity were observed in parental animals.
Relative and absolute weights of testes, epididymides, and seminal
vesicles did not differ between test and control animals. No
reproductive parameters were affected including mean litter weights,
mean pup weights, sex ratios, and gestation periods. Pre-weaning
clinical signs showed no treatment-related effects in pups, nor did
necropsy reveal any effects in decedent or Fl pups. Macroscopic
examination revealed no difference between treated and control animals.
A NOAEL of 1,000 mg/kg/day for reproductive effects can be deduced.
In a rat developmental toxicity study, APG (C12-
C14) was administered by gavage at dose levels of 0, 100,
300, and 1,000 mg/kg/day on gestation days 6 to 15. No treatment-
related maternal deaths; clinical signs; or decreases in mean body
weight, weight gain, corrected weight gain, or gross lesions were
observed in this study. In addition, there were no treatment-related
developmental effects (e.g., external abnormalities, visceral
abnormalities, or skeletal malformations/variations). Therefore, the
developmental and maternal NOAEL is 1,000 mg/kg/day. A LOAEL was not
determined.
No immunotoxicity or neurotoxicity studies are available in the
database; however, APGs (C8-C10) are unlikely to
produce neurotoxicity or evoke immunological response given the lack of
any toxicity, including any immunotoxicity or neurotoxicity, at high
doses (1,000 mg/kg/day). Mutagenicity studies on various chain
[[Page 65564]]
lengths of APGs were negative indicating that APGs are not likely to be
mutagenic. No carcinogenicity studies are available on APGs; however,
APGs are not expected to be carcinogenic based on lack of mutagenicity,
lack of any systemic toxicity at doses up to and including 1,000 mg/kg/
day, and the rapid metabolism of these chemicals to sugars and alcohols
and excretion from the body.
B. Toxicological Points of Departure/Levels of Concern
Metabolism studies on structurally related chemicals indicate that
the body can effectively metabolize D-glucopyranose, oligomeric,
C10-C16-alkyl glycosides to water-soluble
substances (predominantly sugar and various alcohols) that are readily
excreted from the body. No adverse effects were seen any of the repeat
dose studies conducted via the oral route of exposure at or above the
limit dose. No endpoint of concern was identified based on the
available studies in the database.
C. Exposure Assessment
Because no endpoint of concern was identified based upon available
data, a qualitative risk assessment was conducted.
1. Dietary exposure from food and feed uses. In evaluating dietary
exposure to D-Glucopyranose, oligomeric, decyl octyl glycosides, EPA
considered exposure under the proposed exemption from the requirement
of a tolerance. For purposes of this action, EPA qualitatively assessed
dietary exposures from D-Glucopyranose, oligomeric, decyl octyl
glycosides as follows:
Dietary exposure could potentially occur from consuming foods
directly treated with pesticide products containing the inert
ingredient. In addition, dietary exposure to APGs could occur as a
result of contact with surfaces treated with antimicrobial formulations
containing the inert ingredient, including food-contact surfaces in
public eating places, dairy-processing equipment, or food-processing
equipment and utensils. Dietary exposure may also come from consuming
animal products from animals exposed to the inert ingredient via
pesticide application or from eating feed treated with pesticide
products containing the inert ingredient.
2. Dietary exposure from drinking water. Dietary exposure from
drinking water to D-Glucopyranose, oligomeric, decyl octyl glycosides
can occur by drinking water that has been contaminated by contact with
pesticide treated areas, such as countertops. Since an endpoint for
risk assessment was not identified, a quantitative dietary exposure
assessment from drinking water for D-Glucopyranose, oligomeric, decyl
octyl glycosides was not conducted.
3. From non-dietary exposure. The term ``residential exposure'' is
used in this document to refer to non-occupational, non-dietary
exposure (e.g., textiles (clothing and diapers), carpets, swimming
pools, and hard surface disinfection on walls, floors, tables). APGs
are used in laundry detergents, hard surface and household cleaners, as
rinse aids in dishwashers and in personal care products. Non-dietary
exposure could result from both pesticidal and non-pesticidal uses.
4. Cumulative effects from substances with a common mechanism of
toxicity. Section 408(b)(2)(D)(v) of FFDCA requires that, when
considering whether to establish, modify, or revoke a tolerance, the
Agency consider ``available information'' concerning the cumulative
effects of a particular pesticide's residues and ``other substances
that have a common mechanism of toxicity.''
EPA has not found D-Glucopyranose, oligomeric, decyl octyl
glycosides to share a common mechanism of toxicity with any other
substances, and D-Glucopyranose, oligomeric, decyl octyl glycosides
does not appear to produce a toxic metabolite produced by other
substances. For the purposes of this tolerance action, therefore, EPA
has assumed that D-Glucopyranose, oligomeric, decyl octyl glycosides
does not have a common mechanism of toxicity with other substances. For
information regarding EPA's efforts to determine which chemicals have a
common mechanism of toxicity and to evaluate the cumulative effects of
such chemicals, see EPA's Web site at https://www.epa.gov/pesticides/cumulative.
D. Safety Factor for Infants and Children
As part of its qualitative assessment, the Agency did not use
safety factors for assessing risk, and no additional safety factor is
needed for assessing risk to infants and children. The toxicity
database for APGs contains several acute studies, a 90-day oral
toxicity study, a 14-dermal study, a developmental toxicity study, and
a reproductive screening toxicity study. No hazard was identified based
on those studies. The toxicity database does not contain a
carcinogenicity study, an immunotoxicity study, or a neurotoxicity
study, but for the reasons stated in Unit IV.A., the Agency has
concluded that there are no concerns for carcinogenicity,
immunotoxicity, or neurotoxicity for this chemical. No developmental or
reproductive effects were seen in the available studies. Thus, there is
no residual uncertainty regarding prenatal and/or postnatal toxicity of
D-Glucopyrnose, oligomeric, decyl octyl glycosides.
Based on this information, there is no concern at this time for
increased sensitivity to infants and children to D-Glucopyrnose,
oligomeric, decyl octyl glycosides when used as an inert ingredient in
antimicrobial formulations applied to food-contact surfaces in public
eating places, dairy-processing equipment, and food-processing
equipment and utensils.
E. Aggregate Risks and Determination of Safety
Taking into consideration all available information on D-
Glucopyranose, oligomeric, decyl octyl glycosides, EPA has determined
that there is a reasonable certainty that no harm to any population
subgroup will result from aggregate exposure to D-Glucopyranose,
oligomeric, decyl octyl glycosides under reasonably foreseeable
circumstances. Therefore, the establishment of an exemption from
tolerance under 40 CFR 180.940(a) for residues of D-Glucopyranose,
oligomeric, decyl octyl glycosides when used as an inert ingredient in
in antimicrobial food-contact surface sanitizing solutions is safe
under FFDCA section 408.
V. Other Considerations
A. Analytical Enforcement Methodology
An analytical method is not required for enforcement purposes since
the Agency is establishing an exemption from the requirement of a
tolerance without any numerical limitation.
B. Revisions to Petitioned-For Tolerances
Alkyl (C8-C10) polyglycosides and D-
Glucopyranose, oligomeric, decyl octyl glycosides are alternate names
for the chemical with the CAS Reg. No. 68515-73-1 and therefore,
represent the same chemical. EPA is using the latter name because it is
the one used in the Chemical Abstract (CA) Index and the one EPA has
used to establish other exemptions from the requirement of tolerance
for this chemical.
VI. Conclusions
Therefore, an exemption from the requirement of a tolerance is
established under 40 CFR 180.940(a) for D-Glucopyranose, oligomeric,
decyl octyl glycosides (CAS Reg. No. 68515-73-1) when used as an inert
ingredient (surfactant) in antimicrobial
[[Page 65565]]
formulations (i.e., food contact surface sanitizing solutions) applied
to food-contact surfaces in public eating places, dairy-processing
equipment, and food-processing equipment and utensils.
VII. Statutory and Executive Order Reviews
This final rule establishes an exemption from the requirement of a
tolerance under FFDCA section 408(d) in response to a petition
submitted to the Agency. The Office of Management and Budget (OMB) has
exempted these types of actions from review under Executive Order
12866, entitled ``Regulatory Planning and Review'' (58 FR 51735,
October 4, 1993). Because this final rule has been exempted from review
under Executive Order 12866, this final rule is not subject to
Executive Order 13211, entitled ``Actions Concerning Regulations That
Significantly Affect Energy Supply, Distribution, or Use'' (66 FR
28355, May 22, 2001) or Executive Order 13045, entitled ``Protection of
Children from Environmental Health Risks and Safety Risks'' (62 FR
19885, April 23, 1997). This final rule does not contain any
information collections subject to OMB approval under the Paperwork
Reduction Act (PRA) (44 U.S.C. 3501 et seq.), nor does it require any
special considerations under Executive Order 12898, entitled ``Federal
Actions to Address Environmental Justice in Minority Populations and
Low-Income Populations'' (59 FR 7629, February 16, 1994).
Since tolerances and exemptions that are established on the basis
of a petition under FFDCA section 408(d), such as the exemption in this
final rule, do not require the issuance of a proposed rule, the
requirements of the Regulatory Flexibility Act (RFA) (5 U.S.C. 601 et
seq.), do not apply.
This final rule directly regulates growers, food processors, food
handlers, and food retailers, not States or tribes, nor does this
action alter the relationships or distribution of power and
responsibilities established by Congress in the preemption provisions
of FFDCA section 408(n)(4). As such, the Agency has determined that
this action will not have a substantial direct effect on States or
tribal governments, on the relationship between the national government
and the States or tribal governments, or on the distribution of power
and responsibilities among the various levels of government or between
the Federal Government and Indian Tribes. Thus, the Agency has
determined that Executive Order 13132, entitled ``Federalism'' (64 FR
43255, August 10, 1999) and Executive Order 13175, entitled
``Consultation and Coordination with Indian Tribal Governments'' (65 FR
67249, November 9, 2000) do not apply to this final rule. In addition,
this final rule does not impose any enforceable duty or contain any
unfunded mandate as described under Title II of the Unfunded Mandates
Reform Act of 1995 (UMRA) (2 U.S.C. 1501 et seq.).
This action does not involve any technical standards that would
require Agency consideration of voluntary consensus standards pursuant
to section 12(d) of the National Technology Transfer and Advancement
Act of 1995 (NTTAA) (15 U.S.C. 272 note).
VIII. Congressional Review Act
Pursuant to the Congressional Review Act (5 U.S.C. 801 et seq.),
EPA will submit a report containing this rule and other required
information to the U.S. Senate, the U.S. House of Representatives, and
the Comptroller General of the United States prior to publication of
the rule in the Federal Register. This action is not a ``major rule''
as defined by 5 U.S.C. 804(2).
List of Subjects in 40 CFR Part 180
Environmental protection, Administrative practice and procedure,
Agricultural commodities, Pesticides and pests, Reporting and
recordkeeping requirements.
Dated: October 22, 2013.
Lois Rossi,
Director, Registration Division, Office of Pesticide Programs.
Therefore, 40 CFR chapter I is amended as follows:
PART 180--[AMENDED]
0
1. The authority citation for part 180 continues to read as follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
0
2. In Sec. 180.940, add alphabetically the following entry to the
table in paragraph (a) to read as follows:
Sec. 180.940 Tolerance exemptions for active and inert ingredients
for use in antimicrobial formulations (Food-contact surface sanitizing
solutions).
* * * * *
(a) * * *
----------------------------------------------------------------------------------------------------------------
Pesticide chemical CAS Reg. No. Limits
----------------------------------------------------------------------------------------------------------------
* * * * * * *
D-Glucopyranose, oligomeric, decyl octyl glycosides...... 68515-73-1 None
* * * * * * *
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* * * * *
[FR Doc. 2013-26241 Filed 10-31-13; 8:45 am]
BILLING CODE 6560-50-P