Guidance for Tobacco Retailers on Tobacco Retailer Training Programs; Availability, 54657-54658 [2013-21547]
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ehiers on DSK2VPTVN1PROD with NOTICES
Federal Register / Vol. 78, No. 172 / Thursday, September 5, 2013 / Notices
clinical data) was $224,352,000. (Note:
no investigational new drug (IND)
review costs are included in this
amount.) A total of 18 of these
applications (12 NDAs [excluding the
President’s Emergency Plan for Aids
Relief NDAs] and 6 BLAs) received
priority review, which would mean that
the remaining 36 received standard
reviews. Because a priority review
compresses a review that ordinarily
takes 10 months into 6 months, FDA
estimates that a multiplier of 1.67 (10
months divided by 6 months) should be
applied to non-priority review costs in
estimating the effort and cost of a
priority review as compared to a
standard review. This multiplier is
consistent with published research on
this subject. In the article ‘‘Developing
Drugs for Developing Countries,’’
published in Health Affairs, Volume 25,
Number 2, in 2006, the comparison of
historical average review times by David
B. Ridley, Henry G. Grabowski, and
Jeffrey L. Moe supports a priority review
multiplier in the range of 1.48 to 2.35.
The multiplier derived by FDA falls
well below the midpoint of this range.
Using FY 2012 figures, the costs of a
priority and standard review are
estimated using the following formula:
(18 a × 1.67) + (36 a) = $224,352,000
where ‘‘a’’ is the cost of a standard
review and ‘‘a times 1.67’’ is the cost of
a priority review. Using this formula,
the cost of a standard review for NMEs
is calculated to be $3,396,000 (rounded
to the nearest thousand dollars) and the
cost of a priority review for NMEs is
1.67 times that amount, or $5,671,000
(rounded to the nearest thousand
dollars). The difference between these
two cost estimates, or $2,275,000,
represents the incremental cost of
conducting a priority review rather than
a standard review.
Section 524 of the FD&C Act specifies
that the fee amount should be based on
the average cost incurred by the Agency
for a priority review in the previous FY.
FDA is setting fees for FY 2014, and the
previous fiscal year is FY 2013.
However, the FY 2013 submission
cohort has not been closed out yet, and
the cost data for FY 2013 are not
complete. The latest year for which FDA
has complete cost data is FY 2012, so
that must be adjusted for inflation in
order to estimate the FY 2013 cost.
Accordingly, FDA will adjust the FY
2012 incremental cost figure by the
average amount by which FDA’s average
costs increased in the 3 years prior to
FY 2013, to adjust the FY 2012 amount
for cost increases in FY 2013. That
figure, published in the Federal Register
notice on August 2, 2013 (see 78 FR
VerDate Mar<15>2010
14:10 Sep 04, 2013
Jkt 229001
46980 at 46982), setting PDUFA fees for
FY 2014, is 2.20 percent. Increasing the
FY 2012 incremental priority review
cost figure of $2,275,000 by 2.20 percent
results in an estimated cost of
$2,325,000 (rounded to the nearest
thousand dollars). This is the priority
review user fee amount for FY 2014 that
must be submitted with a priority
review voucher in FY 2014, in addition
to any PDUFA fee that is required for
such an application.
III. Priority Review Fee Schedule for
FY 2014
The fee rate for FY 2014 is set out in
Table 1 of this document:
TABLE 1—PRIORITY REVIEW
SCHEDULE FOR FY 2014
Fee category
Fee rate for
FY 2014
Applications Submitted with
a Priority Review Voucher
in Addition to the Normal
PDUFA Fee .......................
$2,325,000
IV. Implementation of Priority Review
Fee
Under section 524(c)(4)(A) of the
FD&C Act, the priority review user fee
is due upon submission of the
application for which the priority
review voucher is used. Section
524(c)(4)(B) of the FD&C Act specifies
that the application will be considered
incomplete if the priority review user
fee and all other applicable user fees are
not paid in accordance with FDA
payment procedures. FDA may not grant
a waiver, exemption, reduction, or
refund of any fees due and payable
under this section of the FD&C Act, and
FDA may not collect priority review
voucher fees prior to a relevant
appropriation for fees for that FY.
Beginning with FDA’s appropriation for
FY 2009, the annual appropriation
language states specifically that
‘‘priority review user fees authorized by
21 U.S.C. 360n [section 524 of the FD&C
Act] may be credited to this account, to
remain available until expended.’’ (Pub.
L. 111–8, Section 5, Division A, Title
VI.)
The priority review fee established in
the new fee schedule must be paid for
any application that is received after
September 30, 2013, and submitted with
a priority review voucher. This fee must
be paid in addition to any other fee due
under PDUFA. Payment must be made
in U.S. currency by check, bank draft, or
U.S. postal money order payable to the
order of the Food and Drug
Administration. The user fee
identification (ID) number should be
PO 00000
Frm 00041
Fmt 4703
Sfmt 4703
54657
included on the check, followed by the
words ‘‘Priority Review.’’ Payments can
be mailed to: Food and Drug
Administration, P.O. Box 979107, St.
Louis, MO 63197–9000. If checks are
sent by a courier that requests a street
address, the courier can deliver the
checks to: U.S. Bank, Attention:
Government Lockbox 979107, 1005
Convention Plaza, St. Louis, MO 63101.
(Note: This U.S. Bank address is for
courier delivery only.) The FDA post
office box number (P.O. Box 979107)
must be written on the check. The tax
identification number of FDA is 53–
0196965.
Wire transfer payments may also be
used. Please reference your unique user
fee ID number when completing your
transfer. The originating financial
institution may charge a wire transfer
fee. Please ask your financial institution
about the fee and include it with your
payment to ensure that your fee is fully
paid. The account information is as
follows: New York Federal Reserve
Bank, U.S. Dept. of Treasury, TREAS
NYC, 33 Liberty St., New York, NY
10045, Acct. No.: 75060099, Routing
No.: 021030004, SWIFT: FRNYUS33,
Beneficiary: FDA, 1350 Piccard Dr.,
Rockville, MD 20850.
Dated: August 29, 2013.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2013–21542 Filed 9–4–13; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2010–D–0350]
Guidance for Tobacco Retailers on
Tobacco Retailer Training Programs;
Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is announcing the
availability of a guidance for tobacco
retailers entitled ‘‘Tobacco Retailer
Training Programs.’’ The Family
Smoking Prevention and Tobacco
Control Act (Tobacco Control Act) does
not require retailers to implement
retailer training programs. However, the
Tobacco Control Act does provide for
lower civil money penalties for
violations of sale and distribution,
including youth access, advertising, and
promotion restrictions issued under the
Federal Food, Drug, and Cosmetic Act
SUMMARY:
E:\FR\FM\05SEN1.SGM
05SEN1
54658
Federal Register / Vol. 78, No. 172 / Thursday, September 5, 2013 / Notices
ehiers on DSK2VPTVN1PROD with NOTICES
(the FD&C Act), as amended by the
Tobacco Control Act, for retailers who
have implemented a training program
that complies with standards developed
by FDA for such programs. FDA intends
to issue regulations establishing
standards for approved retailer training
programs. In the interim, this guidance
document is intended to assist tobacco
retailers who wish to implement
training programs for employees.
DATES: Submit either electronic or
written comments on this guidance at
any time. General comments on Agency
guidance documents are welcome at any
time.
ADDRESSES: Submit written requests for
single copies of this guidance to the
Center for Tobacco Products, Food and
Drug Administration, 9200 Corporate
Blvd., Rockville, MD 20850–3229. Send
one self-addressed adhesive label to
assist that office in processing your
request or include a fax number to
which the guidance document may be
sent. See the SUPPLEMENTARY
INFORMATION section for electronic
access to the guidance document.
Submit electronic comments on the
guidance to https://www.regulations.gov.
Submit written comments on the
guidance to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, rm.
1061, Rockville, MD 20852.
FOR FURTHER INFORMATION CONTACT: Beth
Buckler, Center for Tobacco Products,
Food and Drug Administration, 9200
Corporate Blvd., Rockville, MD 20850–
3229, 1–877–287–1373, beth.buckler@
fda.hhs.gov.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of
a guidance for tobacco retailers entitled
‘‘Tobacco Retailer Training Programs.’’
This guidance document is intended to
assist tobacco retailers who wish to
implement training programs for
employees.
On June 22, 2009, the President
signed the Tobacco Control Act (Pub. L.
111–31; 123 Stat. 1776) into law. The
Tobacco Control Act grants FDA
important authority to regulate the
manufacture, marketing, and
distribution of tobacco products to
protect the public health generally and
to reduce tobacco use by minors.
Among its many provisions, section
906(d) of the FD&C Act (21 U.S.C.
387f(d)), as amended by the Tobacco
Control Act, states that ‘‘[t]he Secretary
may by regulation require restrictions
on the sale and distribution of a tobacco
product, including restrictions on the
access to, and the advertising and
VerDate Mar<15>2010
14:10 Sep 04, 2013
Jkt 229001
promotion of, the tobacco product, if the
Secretary determines that such
regulation would be appropriate for the
protection of the public health.’’
In accordance with section 102 of the
Tobacco Control Act (21 U.S.C. 387a-1),
FDA re-issued its 1996 final regulation
restricting the sale and distribution of
cigarettes and smokeless tobacco
products (75 FR 13225, March 19, 2010).
The regulation is deemed to be issued
under chapter 9 of the FD&C Act, as
amended by the Tobacco Control Act
(section 102(a)(1)(A) of the Tobacco
Control Act). The regulation contains
provisions designed to limit young
people’s access to cigarettes and
smokeless tobacco products, as well as
restrictions on advertising and
promotion of such products, to curb the
appeal of these products to minors (part
1140 (21 CFR part 1140)).
Section 103(q)(2) of the Tobacco
Control Act (21 U.S.C. 333 note)
includes two schedules for assessing the
maximum civil money penalties against
retailers for violations of restrictions
issued under section 906(d) of the FD&C
Act, as amended by the Tobacco Control
Act, pertaining to the sale and
distribution, including youth access,
and advertising and promotion of
tobacco products. Under each schedule,
violators are subject to increasing
penalties for multiple violations within
prescribed time periods. For the first
three violations in a 24-month period,
retailers with an approved training
program are subject to lower penalties
than retailers without such programs.
Section 103(q)(2)(B) defines ‘‘approved
training program’’ as a training program
that complies with standards developed
by FDA for such programs.
FDA intends to issue regulations
establishing standards for approved
retailer training programs. In the
interim, however, FDA is issuing this
guidance to provide recommendations
on elements the Agency believes should
be included in a retailer training
program. Until FDA issues these
regulations, the Agency intends to use
the lower maximum civil money
penalties schedule for all retailers who
violate the regulations restricting the
sale and distribution of cigarettes and
smokeless tobacco products (part 1140),
whether or not they have implemented
a training program. However, FDA may
consider further reducing the civil
money penalty for retailers who have
implemented a training program.
In the Federal Register of July 16,
2010 (75 FR 41498), FDA announced the
availability of a draft guidance entitled
‘‘Tobacco Retailer Training Programs.’’
The Agency considered received
comments as it finalized this guidance.
PO 00000
Frm 00042
Fmt 4703
Sfmt 4703
In addition, editorial changes were
made to improve clarity.
II. Significance of Guidance
This level 1 guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The guidance represents the Agency’s
current thinking on tobacco retailer
training programs. It does not create or
confer any rights for or on any person
and does not operate to bind FDA or the
public. An alternative approach may be
used if such approach satisfies the
requirements of the applicable statutes
and regulations.
III. Comments
Interested persons may submit either
written comments regarding this
document to the Division of Dockets
Management (see ADDRESSES) or
electronic comments to https://
www.regulations.gov. It is only
necessary to send one set of comments.
Identify comments with the docket
number found in brackets in the
heading of this document. Received
comments may be seen in the Division
of Dockets Management between 9 a.m.
and 4 p.m., Monday through Friday, and
will be posted to the docket at https://
www.regulations.gov.
IV. Paperwork Reduction Act of 1995
This guidance contains information
collection provisions that are subject to
review by the Office of Management and
Budget (OMB) under the Paperwork
Reduction Act of 1995 (44 U.S.C. 3501–
3520). The collection of information in
this guidance was approved under OMB
control number 0910–0745.
V. Electronic Access
Persons with access to the Internet
may obtain the document at either
https://www.regulations.gov or https://
www.fda.gov/TobaccoProducts/
GuidanceComplianceRegulatory
Information/default.htm.
Dated: August 30, 2013.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2013–21547 Filed 9–4–13; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2013–N–0001]
Allergenic Products Advisory
Committee; Notice of Meeting
AGENCY:
Food and Drug Administration,
HHS.
E:\FR\FM\05SEN1.SGM
05SEN1
Agencies
[Federal Register Volume 78, Number 172 (Thursday, September 5, 2013)]
[Notices]
[Pages 54657-54658]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2013-21547]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2010-D-0350]
Guidance for Tobacco Retailers on Tobacco Retailer Training
Programs; Availability
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is announcing the
availability of a guidance for tobacco retailers entitled ``Tobacco
Retailer Training Programs.'' The Family Smoking Prevention and Tobacco
Control Act (Tobacco Control Act) does not require retailers to
implement retailer training programs. However, the Tobacco Control Act
does provide for lower civil money penalties for violations of sale and
distribution, including youth access, advertising, and promotion
restrictions issued under the Federal Food, Drug, and Cosmetic Act
[[Page 54658]]
(the FD&C Act), as amended by the Tobacco Control Act, for retailers
who have implemented a training program that complies with standards
developed by FDA for such programs. FDA intends to issue regulations
establishing standards for approved retailer training programs. In the
interim, this guidance document is intended to assist tobacco retailers
who wish to implement training programs for employees.
DATES: Submit either electronic or written comments on this guidance at
any time. General comments on Agency guidance documents are welcome at
any time.
ADDRESSES: Submit written requests for single copies of this guidance
to the Center for Tobacco Products, Food and Drug Administration, 9200
Corporate Blvd., Rockville, MD 20850-3229. Send one self-addressed
adhesive label to assist that office in processing your request or
include a fax number to which the guidance document may be sent. See
the SUPPLEMENTARY INFORMATION section for electronic access to the
guidance document.
Submit electronic comments on the guidance to https://www.regulations.gov. Submit written comments on the guidance to the
Division of Dockets Management (HFA-305), Food and Drug Administration,
5630 Fishers Lane, rm. 1061, Rockville, MD 20852.
FOR FURTHER INFORMATION CONTACT: Beth Buckler, Center for Tobacco
Products, Food and Drug Administration, 9200 Corporate Blvd.,
Rockville, MD 20850-3229, 1-877-287-1373, beth.buckler@fda.hhs.gov.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of a guidance for tobacco
retailers entitled ``Tobacco Retailer Training Programs.'' This
guidance document is intended to assist tobacco retailers who wish to
implement training programs for employees.
On June 22, 2009, the President signed the Tobacco Control Act
(Pub. L. 111-31; 123 Stat. 1776) into law. The Tobacco Control Act
grants FDA important authority to regulate the manufacture, marketing,
and distribution of tobacco products to protect the public health
generally and to reduce tobacco use by minors.
Among its many provisions, section 906(d) of the FD&C Act (21
U.S.C. 387f(d)), as amended by the Tobacco Control Act, states that
``[t]he Secretary may by regulation require restrictions on the sale
and distribution of a tobacco product, including restrictions on the
access to, and the advertising and promotion of, the tobacco product,
if the Secretary determines that such regulation would be appropriate
for the protection of the public health.''
In accordance with section 102 of the Tobacco Control Act (21
U.S.C. 387a-1), FDA re-issued its 1996 final regulation restricting the
sale and distribution of cigarettes and smokeless tobacco products (75
FR 13225, March 19, 2010). The regulation is deemed to be issued under
chapter 9 of the FD&C Act, as amended by the Tobacco Control Act
(section 102(a)(1)(A) of the Tobacco Control Act). The regulation
contains provisions designed to limit young people's access to
cigarettes and smokeless tobacco products, as well as restrictions on
advertising and promotion of such products, to curb the appeal of these
products to minors (part 1140 (21 CFR part 1140)).
Section 103(q)(2) of the Tobacco Control Act (21 U.S.C. 333 note)
includes two schedules for assessing the maximum civil money penalties
against retailers for violations of restrictions issued under section
906(d) of the FD&C Act, as amended by the Tobacco Control Act,
pertaining to the sale and distribution, including youth access, and
advertising and promotion of tobacco products. Under each schedule,
violators are subject to increasing penalties for multiple violations
within prescribed time periods. For the first three violations in a 24-
month period, retailers with an approved training program are subject
to lower penalties than retailers without such programs. Section
103(q)(2)(B) defines ``approved training program'' as a training
program that complies with standards developed by FDA for such
programs.
FDA intends to issue regulations establishing standards for
approved retailer training programs. In the interim, however, FDA is
issuing this guidance to provide recommendations on elements the Agency
believes should be included in a retailer training program. Until FDA
issues these regulations, the Agency intends to use the lower maximum
civil money penalties schedule for all retailers who violate the
regulations restricting the sale and distribution of cigarettes and
smokeless tobacco products (part 1140), whether or not they have
implemented a training program. However, FDA may consider further
reducing the civil money penalty for retailers who have implemented a
training program.
In the Federal Register of July 16, 2010 (75 FR 41498), FDA
announced the availability of a draft guidance entitled ``Tobacco
Retailer Training Programs.'' The Agency considered received comments
as it finalized this guidance. In addition, editorial changes were made
to improve clarity.
II. Significance of Guidance
This level 1 guidance is being issued consistent with FDA's good
guidance practices regulation (21 CFR 10.115). The guidance represents
the Agency's current thinking on tobacco retailer training programs. It
does not create or confer any rights for or on any person and does not
operate to bind FDA or the public. An alternative approach may be used
if such approach satisfies the requirements of the applicable statutes
and regulations.
III. Comments
Interested persons may submit either written comments regarding
this document to the Division of Dockets Management (see ADDRESSES) or
electronic comments to https://www.regulations.gov. It is only necessary
to send one set of comments. Identify comments with the docket number
found in brackets in the heading of this document. Received comments
may be seen in the Division of Dockets Management between 9 a.m. and 4
p.m., Monday through Friday, and will be posted to the docket at https://www.regulations.gov.
IV. Paperwork Reduction Act of 1995
This guidance contains information collection provisions that are
subject to review by the Office of Management and Budget (OMB) under
the Paperwork Reduction Act of 1995 (44 U.S.C. 3501-3520). The
collection of information in this guidance was approved under OMB
control number 0910-0745.
V. Electronic Access
Persons with access to the Internet may obtain the document at
either https://www.regulations.gov or https://www.fda.gov/TobaccoProducts/GuidanceComplianceRegulatoryInformation/default.htm.
Dated: August 30, 2013.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2013-21547 Filed 9-4-13; 8:45 am]
BILLING CODE 4160-01-P