Request for Information About Diethanolamine (CAS No. 111-42-2), 24207-24208 [2013-09651]
Download as PDF
<![CDATA[
Federal Register / Vol. 78, No. 79 / Wednesday, April 24, 2013 / Notices
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Disease Control and
Prevention
[CDC–2013–0005; NIOSH–263]
Request for Information About
Diethanolamine (CAS No. 111–42–2)
National Institute for
Occupational Safety and Health
(NIOSH) of the Centers for Disease
Control and Prevention (CDC),
Department of Health and Human
Services (HHS).
ACTION: Request for information.
AGENCY:
The National Institute for
Occupational Safety and Health
(NIOSH) of the Centers for Disease
Control and Prevention (CDC) intends to
evaluate the scientific data on
diethanolamine, and develop
appropriate communication documents,
such as a Criteria Document, which will
convey the potential health risks,
recommended measures for safe
handling, and establish an updated
Recommended Exposure Limit (REL).
The current NIOSH REL for
diethanolamine is 3 parts per million
(ppm) as a time-weighted average
(TWA) concentration for up to a 10-hr
work shift during a 40-hr workweek.
NIOSH is requesting information on
the following: (1) Published and
unpublished reports and findings from
in vitro and in vivo toxicity studies with
diethanolamine; (2) information on
possible health effects observed in
workers exposed to diethanolamine,
including exposure data and the
method(s) used for sampling and
analyzing exposures; (3) description of
work tasks and scenarios with a
potential for exposure to
diethanolamine; (4) information on
control measures (e.g. engineering
controls, work practices, personal
protective equipment, exposure data
before and after implementation of
control measures) that are being used in
workplaces with potential exposure to
diethanolamine; and (5) surveillance
findings including protocol, methods,
and results.
Public Comment Period: Comments
must be received by June 24, 2013.
ADDRESSES: You may submit comments,
identified by CDC–2013–0005 and
Docket Number NIOSH–263, by either
of the two following methods:
• Federal eRulemaking Portal: https://
www.regulations.gov. Follow the
instructions for submitting comments.
• Mail: NIOSH Docket Office, Robert
A. Taft Laboratories, MS–C34, 4676
tkelley on DSK3SPTVN1PROD with NOTICES
SUMMARY:
VerDate Mar<15>2010
18:05 Apr 23, 2013
Jkt 229001
Columbia Parkway, Cincinnati, OH
45226.
Instructions: All information received
in response to this notice must include
the agency name and docket number
(CDC–2013–0005; NIOSH–263). All
relevant comments received will be
posted without change to https://
www.regulations.gov, including any
personal information provided. All
electronic comments should be
formatted as Microsoft Word. Please
make reference to CDC–2013–0005 and
Docket Number NIOSH–263.
FOR FURTHER INFORMATION CONTACT:
Jennifer Reynolds, MPH, NIOSH, Robert
A Taft Laboratories, MS–C32, 4676
Columbia Parkway, Cincinnati, OH
45226, telephone (513) 533–8531.
SUPPLEMENTARY INFORMATION:
Diethanolamine is a highly reactive
compound. It decomposes on burning
producing toxic fumes. Diethanolamine
reacts violently with oxidants and
strong acids. Diethanolamine is used to
produce surface active agents widely
used in soaps, cosmetics and personal
care items. It also has other uses
including as an absorbent in gas
purification, as a dispersing agent in
agricultural chemicals, a corrosion
inhibitor and wetting agent in
metalworking fluids.
The annual production of
diethanolamine in the United States was
estimated in 1995 to be 106,000 tons
(Technology Planning and Management
Corp, 2002). NIOSH estimates from the
National Occupational Exposure Survey
(NIOSH 1989) that the number of
workers potentially exposed to
diethanolamine is approximately
830,000/year.
Significant occupational exposures to
diethanolamine are through the skin
(dermal) and via inhalation (lung)
during the use of lubricating liquids in
various processes in machine building.
Chronic exposure to diethanolamine can
cause skin sensitization.
Diethanolamine is also corrosive to the
eyes. The current REL for
diethanolamine is 3 ppm as a TWA
concentration for up to a 10-hr work
shift during a 40-hr workweek. The
NIOSH REL was established as a result
of testimony submitted to the
Occupational Safety and Health
Administration (OSHA) on their
proposed rulemaking of Air
Contaminants in 1988. Currently,
concentrations below the REL can be
detected and quantified. As part of an
effort to identify RELs that may not be
adequate to protect workers from
adverse health effects due to exposure,
NIOSH is reexamining the REL for
diethanolamine. There is no OSHA
PO 00000
Frm 00058
Fmt 4703
Sfmt 4703
24207
permissible exposure limit (PEL) for
diethanolamine. The American
Conference of Governmental Hygienists
(ACGIH®) threshold limit value
(TLV®)—TWA for diethanolamine is 1
mg/m3 (inhalable fraction and vapor),
with a Skin notation (indicating danger
of cutaneous absorption), and an A3
carcinogenicity classification
(confirmed animal carcinogen with
unknown relevance to humans).
NIOSH seeks to obtain materials,
including published and unpublished
reports and research findings, to
evaluate the possible health risks of
occupational exposure to
diethanolamine. Examples of requested
information include, but are not limited
to, the following:
(1) Identification of industries or
occupations in which exposures to
diethanolamine may occur.
(2) Trends in the production and use
of diethanolamine.
(3) Description of work tasks and
scenarios with a potential for exposure
to diethanolamine.
(4) Workplace exposure measurement
data of diethanolamine in various types
of industries and jobs.
(5) Case reports or other health
information demonstrating potential
health effects in workers exposed to
diethanolamine.
(6) Research findings from in vitro and
in vivo studies.
(7) Information on control measures
(e.g., engineering controls, work
practices, PPE) being taken to minimize
worker exposure to diethanolamine.
(8) Educational materials for worker
safety and training on the safe handling
of diethanolamine.
(9) Data pertaining to the feasibility of
establishing a more protective REL for
diethanolamine.
(10) Names of substitute chemicals or
processes being used in place of
diethanolamine and type of work tasks.
References
NIOSH [1989]. National occupational
exposure survey analysis of management
interview responses. Vol. III. Pedersen
DH, Sieber WK, eds. Cincinnati, OH:
U.S. Department of Health and Human
Services, Centers for Disease Control,
National Institute for Occupational
Safety and Health, DHHS (NIOSH)
Publication No. 89–103.
Technology Planning and Management
Corporation [2002]. Report on
carcinogens background document for
diethanolamine. Prepared for the U.S.
Department of Health and Human
Services, National Toxicology Program:
Research Triangle Park, NC.
E:\FR\FM\24APN1.SGM
24APN1
24208
Federal Register / Vol. 78, No. 79 / Wednesday, April 24, 2013 / Notices
Dated: April 18, 2013.
John Howard,
Director, National Institute for Occupational
Safety and Health, Centers for Disease Control
and Prevention.
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
[FR Doc. 2013–09651 Filed 4–23–13; 8:45 am]
[CFDA Number: 93.676]
BILLING CODE 4163–19–P
Administration for Children and
Families
Announcement of the Award of 12
Single-Source Program Expansion
Supplement Grants to Unaccompanied
Alien Children’s Shelter Care Grantees
Office of Refugee Resettlement,
Administration for Children and
Families, Department of Health and
Human Services.
AGENCY:
Announcement of the award of
12 single-source program expansion
grants to 10 current grantees to expand
bed capacity and supportive services to
the increasing number of
unaccompanied alien children.
ACTION:
The Administration for
Children and Families (ACF), Office of
Refugee Resettlement (ORR) announces
the award of twelve single-source
program expansion supplement grants
to the following ten current grantees, for
a total of $33,653,092.
SUMMARY:
Location
Children’s Center, Inc ...................................................................................................
BCFS Health and Human Services .............................................................................
Heartland Human Care Services, Inc ..........................................................................
Southwest Key, Inc ......................................................................................................
United States Conference of Catholic Bishops ............................................................
Lutheran Immigration Refugee Services ......................................................................
Lutheran Social Services of the South ........................................................................
His House .....................................................................................................................
Lincoln Hall ...................................................................................................................
Youth For Tomorrow ....................................................................................................
tkelley on DSK3SPTVN1PROD with NOTICES
Organization
Galveston, TX ...........................................
San Antonio, TX .......................................
Chicago, IL ................................................
Austin, TX .................................................
Washington, DC ........................................
Baltimore, MD ...........................................
Austin, TX .................................................
Opa Locka, FL ..........................................
Lincolndale, NY .........................................
Bristow, VA ...............................................
These supplement grants will support
the expansion of bed capacity and
supportive services to meet the number
of unaccompanied alien children
referrals from the Department of
Homeland Security (DHS). The funding
program is mandated by section 462 of
the Homeland Security Act to ensure
appropriate placement of all referrals
from the DHS. The program is tied to
DHS apprehension strategies and
sporadic number of border crossers.
Award funds will support services to
unaccompanied alien children through
September 30, 2013.
DATES: The period of support under
these supplements is October 1, 2012
through September 30, 2013.
FOR FURTHER INFORMATION CONTACT:
Jallyn Sualog, Acting Director, Division
of Children’s Services, Office of Refugee
Resettlement, 901 D Street SW.,
Washington, Telephone (202) 401–4997.
Email:jallyn.sualog@acf.hhs.gov.
SUPPLEMENTARY INFORMATION: Since the
beginning of FY 13, the Unaccompanied
Alien Children (UAC) program has seen
a dramatic increase in the number of
DHS referrals. The influx of border
crossers referred by DHS has grown
beyond anticipated rates and has
resulted in the program needing a
significant increase in the number of
shelter beds and supportive services.
The UAC program has specific
requirements for the provision of
services to unaccompanied alien
children. These grantee organizations
VerDate Mar<15>2010
18:05 Apr 23, 2013
Jkt 229001
are the only entities with the
infrastructure, licensing, experience,
and appropriate level of trained staff to
meet the required service requirements
and the urgent need for the expansion
of services required to respond to
unexpected arrivals of unaccompanied
children. The program expansion
supplement will support such services
and alleviate the buildup of children
waiting in border patrol stations for
placement in shelter care.
Statutory Authority: Section 462 of the
Homeland Security Act, (6 U.S.C. 279) and
sections 235(c) and 235(d) of the William
Wilberforce Trafficking Victims Protection
Reauthorization Act of 2008, (8 U.S.C.
1232(c) and 1232(d)).
Eskinder Negash,
Director, Office of Refugee Resettlement.
[FR Doc. 2013–09699 Filed 4–23–13; 8:45 am]
BILLING CODE 4184–45–P
ACTION:
Amount
$354,377
11,826,867
1,459,119
12,450,000
300,000
2,500,000
2,171,142
950,000
523,520
1,118,067
Notice.
The Food and Drug
Administration (FDA) is announcing an
opportunity for public comment on the
proposed collection of certain
information by the Agency. Under the
Paperwork Reduction Act of 1995 (the
PRA), Federal Agencies are required to
publish notice in the Federal Register
concerning each proposed collection of
information and to allow 60 days for
public comment in response to the
notice. This notice solicits comments on
the regulations that provide protection
for human subjects of clinical
investigations conducted in support of
applications or submissions to FDA for
FDA-regulated products. The
regulations provide protection of the
rights, safety, and welfare of human
subjects involved in research activities
within FDA’s jurisdiction.
SUMMARY:
Submit either electronic or
written comments on the collection of
information by June 24, 2013.
DATES:
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2013–N–0403]
Agency Information Collection
Activities; Proposed Collection;
Comment Request; Protection of
Human Subjects: Informed Consent;
Institutional Review Boards
AGENCY:
Food and Drug Administration,
HHS.
PO 00000
Frm 00059
Fmt 4703
Sfmt 4703
Submit electronic
comments on the collection of
information to https://
www.regulations.gov. Submit written
comments on the collection of
information to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, rm.
1061, Rockville, MD 20852. All
comments should be identified with the
docket number found in brackets in the
heading of this document.
ADDRESSES:
E:\FR\FM\24APN1.SGM
24APN1
]]>Agencies
[Federal Register Volume 78, Number 79 (Wednesday, April 24, 2013)]
[Notices]
[Pages 24207-24208]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2013-09651]
[[Page 24207]]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[CDC-2013-0005; NIOSH-263]
Request for Information About Diethanolamine (CAS No. 111-42-2)
AGENCY: National Institute for Occupational Safety and Health (NIOSH)
of the Centers for Disease Control and Prevention (CDC), Department of
Health and Human Services (HHS).
ACTION: Request for information.
-----------------------------------------------------------------------
SUMMARY: The National Institute for Occupational Safety and Health
(NIOSH) of the Centers for Disease Control and Prevention (CDC) intends
to evaluate the scientific data on diethanolamine, and develop
appropriate communication documents, such as a Criteria Document, which
will convey the potential health risks, recommended measures for safe
handling, and establish an updated Recommended Exposure Limit (REL).
The current NIOSH REL for diethanolamine is 3 parts per million (ppm)
as a time-weighted average (TWA) concentration for up to a 10-hr work
shift during a 40-hr workweek.
NIOSH is requesting information on the following: (1) Published and
unpublished reports and findings from in vitro and in vivo toxicity
studies with diethanolamine; (2) information on possible health effects
observed in workers exposed to diethanolamine, including exposure data
and the method(s) used for sampling and analyzing exposures; (3)
description of work tasks and scenarios with a potential for exposure
to diethanolamine; (4) information on control measures (e.g.
engineering controls, work practices, personal protective equipment,
exposure data before and after implementation of control measures) that
are being used in workplaces with potential exposure to diethanolamine;
and (5) surveillance findings including protocol, methods, and results.
Public Comment Period: Comments must be received by June 24, 2013.
ADDRESSES: You may submit comments, identified by CDC-2013-0005 and
Docket Number NIOSH-263, by either of the two following methods:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the instructions for submitting comments.
Mail: NIOSH Docket Office, Robert A. Taft Laboratories,
MS-C34, 4676 Columbia Parkway, Cincinnati, OH 45226.
Instructions: All information received in response to this notice
must include the agency name and docket number (CDC-2013-0005; NIOSH-
263). All relevant comments received will be posted without change to
https://www.regulations.gov, including any personal information
provided. All electronic comments should be formatted as Microsoft
Word. Please make reference to CDC-2013-0005 and Docket Number NIOSH-
263.
FOR FURTHER INFORMATION CONTACT: Jennifer Reynolds, MPH, NIOSH, Robert
A Taft Laboratories, MS-C32, 4676 Columbia Parkway, Cincinnati, OH
45226, telephone (513) 533-8531.
SUPPLEMENTARY INFORMATION: Diethanolamine is a highly reactive
compound. It decomposes on burning producing toxic fumes.
Diethanolamine reacts violently with oxidants and strong acids.
Diethanolamine is used to produce surface active agents widely used in
soaps, cosmetics and personal care items. It also has other uses
including as an absorbent in gas purification, as a dispersing agent in
agricultural chemicals, a corrosion inhibitor and wetting agent in
metalworking fluids.
The annual production of diethanolamine in the United States was
estimated in 1995 to be 106,000 tons (Technology Planning and
Management Corp, 2002). NIOSH estimates from the National Occupational
Exposure Survey (NIOSH 1989) that the number of workers potentially
exposed to diethanolamine is approximately 830,000/year.
Significant occupational exposures to diethanolamine are through
the skin (dermal) and via inhalation (lung) during the use of
lubricating liquids in various processes in machine building. Chronic
exposure to diethanolamine can cause skin sensitization. Diethanolamine
is also corrosive to the eyes. The current REL for diethanolamine is 3
ppm as a TWA concentration for up to a 10-hr work shift during a 40-hr
workweek. The NIOSH REL was established as a result of testimony
submitted to the Occupational Safety and Health Administration (OSHA)
on their proposed rulemaking of Air Contaminants in 1988. Currently,
concentrations below the REL can be detected and quantified. As part of
an effort to identify RELs that may not be adequate to protect workers
from adverse health effects due to exposure, NIOSH is reexamining the
REL for diethanolamine. There is no OSHA permissible exposure limit
(PEL) for diethanolamine. The American Conference of Governmental
Hygienists (ACGIH[supreg]) threshold limit value (TLV[supreg])--TWA for
diethanolamine is 1 mg/m\3\ (inhalable fraction and vapor), with a Skin
notation (indicating danger of cutaneous absorption), and an A3
carcinogenicity classification (confirmed animal carcinogen with
unknown relevance to humans).
NIOSH seeks to obtain materials, including published and
unpublished reports and research findings, to evaluate the possible
health risks of occupational exposure to diethanolamine. Examples of
requested information include, but are not limited to, the following:
(1) Identification of industries or occupations in which exposures
to diethanolamine may occur.
(2) Trends in the production and use of diethanolamine.
(3) Description of work tasks and scenarios with a potential for
exposure to diethanolamine.
(4) Workplace exposure measurement data of diethanolamine in
various types of industries and jobs.
(5) Case reports or other health information demonstrating
potential health effects in workers exposed to diethanolamine.
(6) Research findings from in vitro and in vivo studies.
(7) Information on control measures (e.g., engineering controls,
work practices, PPE) being taken to minimize worker exposure to
diethanolamine.
(8) Educational materials for worker safety and training on the
safe handling of diethanolamine.
(9) Data pertaining to the feasibility of establishing a more
protective REL for diethanolamine.
(10) Names of substitute chemicals or processes being used in place
of diethanolamine and type of work tasks.
References
NIOSH [1989]. National occupational exposure survey analysis of
management interview responses. Vol. III. Pedersen DH, Sieber WK,
eds. Cincinnati, OH: U.S. Department of Health and Human Services,
Centers for Disease Control, National Institute for Occupational
Safety and Health, DHHS (NIOSH) Publication No. 89-103.
Technology Planning and Management Corporation [2002]. Report on
carcinogens background document for diethanolamine. Prepared for the
U.S. Department of Health and Human Services, National Toxicology
Program: Research Triangle Park, NC.
[[Page 24208]]
Dated: April 18, 2013.
John Howard,
Director, National Institute for Occupational Safety and Health,
Centers for Disease Control and Prevention.
[FR Doc. 2013-09651 Filed 4-23-13; 8:45 am]
BILLING CODE 4163-19-P
