Draft Report on Carcinogens Monographs for 1-Bromopropane and Cumene; Availability of Documents; Request for Comments; Notice of Meeting, 4419-4421 [2013-01242]

Download as PDF Federal Register / Vol. 78, No. 14 / Tuesday, January 22, 2013 / Notices information. The Web site provides an alternative to the paper request process by enabling online submission of export certificate applications. IV. Paperwork Reduction Act of 1995 This document refers to previously approved collections of information found in FDA regulations. These collections of information are subject to review by OMB under the Paperwork Reduction Act of 1995 (44 U.S.C. 3501– 3520). The collections of information in CECATS and Forms FDA 3613, 3613a, and 3613c have been approved under OMB control number 0910–0498. Dated: January 15, 2013. Leslie Kux, Assistant Commissioner for Policy. [FR Doc. 2013–01164 Filed 1–18–13; 8:45 am] BILLING CODE 4160–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings tkelley on DSK3SPTVN1PROD with Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict: Cardiovascular Sciences. Date: February 7–8, 2013. Time: 9:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Virtual Meeting). Contact Person: Bradley Nuss, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4142, MSC7814, Bethesda, MD 20892, 301–451– 8754, nussb@csr.nih.gov. Name of Committee: Center for Scientific Review Special Emphasis Panel, PAR–10– 244, Structure and Function of Opioid Receptors. Date: February 11–12, 2013. Time: 8:00 a.m. to 12:00 p.m. VerDate Mar<15>2010 18:11 Jan 18, 2013 Jkt 229001 Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Virtual Meeting). Contact Person: David R. Jollie, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4150, MSC 7806, Bethesda, MD 20892, (301) 435– 1722, jollieda@csr.nih.gov. Name of Committee: Center for Scientific Review Special Emphasis Panel, Biomedical Imaging and Engineering Area Review. Date: February 12, 2013. Time: 1:00 p.m. to 4:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Jan Li, MD, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5106, Bethesda, MD 20892, 301–435–1049, lij21@ csr.nih.gov. Name of Committee: Vascular and Hematology Integrated Review Group, Hypertension and Microcirculation Study Section. Date: February 14, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review and evaluate grant applications. Place: Dallas Marriott Suites Medical— Market Center, 2493 North Stemmons Freeway, Dallas, TX 75207. Contact Person: Ai-Ping Zou, MD, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4118, MSC 7814, Bethesda, MD 20892, 301–408– 9497, zouai@csr.nih.gov. Name of Committee: Infectious Diseases and Microbiology Integrated Review Group, Bacterial Pathogenesis Study Section. Date: February 19, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review and evaluate grant applications. Place: Residence Inn Bethesda, 7335 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Richard G Kostriken, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 3192, MSC 7808, Bethesda, MD 20892, 301–402– 4454, kostrikr@csr.nih.gov. Name of Committee: Vascular and Hematology Integrated Review Group, Molecular and Cellular Hematology Study Section. Date: February 19–20, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: Embassy Suites at the Chevy Chase Pavilion, 4300 Military Road NW., Washington, DC 20015. Contact Person: Luis Espinoza, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 6183, MSC 7804, Bethesda, MD 20892, 301–495– 1213, espinozala@mail.nih.gov. PO 00000 Frm 00043 Fmt 4703 Sfmt 4703 4419 Name of Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict: Integrative Neuroscience. Date: February 19, 2013. Time: 9:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Virtual Meeting). Contact Person: Nicholas Gaiano, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5178, MSC 7844, Bethesda, MD 20892–7844, 301–435–1033, gaianonr@csr.nih.gov. Name of Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict: Nanotechnology and Molecular Substrates in Brain and Retinal Disorders. Date: February 19, 2013. Time: 12:00 p.m. to 3:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Yvonne Bennett, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5199, MSC 7846, Bethesda, MD 20892, 301–379–3793, bennetty@csr.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93.393–93.396, 93.837–93.844, 93.846–93.878, 93.892, 93.893, National Institutes of Health, HHS) Dated: January 15, 2013. Melanie J. Gray, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2013–01096 Filed 1–18–13; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Draft Report on Carcinogens Monographs for 1-Bromopropane and Cumene; Availability of Documents; Request for Comments; Notice of Meeting Peer review meeting of the Draft Report on Carcinogens (RoC) Monographs for 1-Bromopropane and Cumene. These documents were prepared by the Office of the Report on Carcinogens (ORoC), Division of the National Toxicology Program (DNTP), National Institute of Environmental Health Sciences (NIEHS). DATES: Meeting: March 21, 2013, 1:00 p.m. to approximately 5:00 p.m. Eastern Daylight Time (EDT) and March 22, 2013, from 8:30 a.m. until adjournment, approximately 2:00 p.m. EDT. Document Availability: Draft monographs will be available by January SUMMARY: E:\FR\FM\22JAN1.SGM 22JAN1 4420 Federal Register / Vol. 78, No. 14 / Tuesday, January 22, 2013 / Notices 23, 2013, at http://ntp.niehs.nih.gov/go/ 36639. Public Comments Submissions: Deadline is March 7, 2013. Pre-Registration for Meeting and/or Oral Comments: Deadline is March 19, 2013. ADDRESSES: Meeting Location: NIEHS, Keystone Building, Room 1003AB, 530 Davis Drive, Morrisville, NC 27560. Agency Meeting Web page: The draft monographs, draft agenda, registration and other meeting materials are at http://ntp.niehs.nih.gov/go/36639. Webcast: The meeting will be available via webcast at http:// www.niehs.nih.gov/news/video/ index.cfm. Dr. Lori D. White, NTP Designated Federal Official, Office of Liaison, Policy and Review, DNTP, NIEHS, P.O. Box 12233, MD K2–03, Research Triangle Park, NC 27709. Phone: (919) 541–9834, Fax: (301) 480–3272, Email: whiteld@niehs.nih.gov. Hand Delivery/ Courier: 530 Davis Drive, Room 2136, Morrisville, NC 27560. SUPPLEMENTARY INFORMATION: Background: The Report on Carcinogens (RoC) is a congressionally mandated, science-based, public health report that identifies agents, substances, mixtures, or exposures (collectively called ‘‘substances’’) in our environment that may put people in the United States at increased risk for cancer. The NTP prepares the RoC on behalf of the Secretary of Health and Human Services. The NTP follows an established, fourpart process for preparation of the RoC (http://ntp.niehs.nih.gov/go/rocprocess). A RoC Monograph is prepared for each candidate substance selected for review for the RoC. 1-Bromopropane and cumene were selected as candidate substances following solicitation of public comment and review by the NTP Board of Scientific Counselors review on June 21–22, 2012 (http:// ntp.niehs.nih.gov/go/9741). A draft RoC monograph consists of a (1) cancer evaluation component that reviews all information that may bear on a listing decision, assesses its quality and sufficiency for reaching a listing decision, applies the RoC listing criteria to the relevant scientific information, and recommends a listing status for the candidate substance in the RoC and (2) a substance profile that contains the NTP’s preliminary listing recommendation and a summary of the scientific evidence considered key to reaching that recommendation. This meeting is planned for peer review of tkelley on DSK3SPTVN1PROD with FOR FURTHER INFORMATION CONTACT: VerDate Mar<15>2010 18:11 Jan 18, 2013 Jkt 229001 the draft RoC Monographs for 1bromopropane and cumene. 1-Bromopropane (CASRN 106–94–5) is a brominated hydrocarbon that is currently used as a solvent in a variety of industrial and commercial applications. It is used as a solvent cleaner to degrease electronics, precision optics, and metals, as a solvent vehicle in industries that use aerosolized adhesives (e.g., foam cushion manufacturing), as a spot remover in the textile industry, and as a solvent in the dry cleaning industry. Additional information about the review of 1-bromopropane for the RoC is available at http://ntp.niehs.nih.gov/go/ 37896. Cumene (CASRN 98–82–8, isopropylbenzene) is an alkylated benzene found in fossil fuels, such as blended gasoline and kerosene, and products of incomplete combustion. It is a high production volume chemical in the United States with the majority of its use in the synthesis of acetone and phenol. Additional information about the review of cumene for the RoC is available at http://ntp.niehs.nih.gov/go/ 37895. Meeting and Registration: The meeting is open to the public with time set aside for oral public comment; attendance at the NIEHS is limited only by the space available. The meeting is scheduled for March 21, 2013, 1:00 p.m. to approximately 5:00 p.m. EDT and March 22, 2013, from 8:30 a.m. until adjournment, approximately 2:00 p.m. EDT. Two days are set aside for the meeting; however, it may adjourn sooner if the panel completes its peer review of the draft monographs. Preregistration to attend the meeting and/ or provide oral comments is by March 19, 2013, at http://ntp.niehs.nih.gov/go/ 36639. Visitor and security information is available at http://www.niehs.nih.gov/ about/visiting/index.cfm. Individuals with disabilities who need accommodation to participate in this event should contact Danica Andrews at phone: (919) 541–2595 or email: andrewsda@niehs.nih.gov. TTY users should contact the Federal TTY Relay Service at (800) 877–8339. Requests should be made at least five business days in advance of the event. The preliminary agenda and draft monographs should be posted on the NTP Web site (http://ntp.niehs.nih.gov/ go/36639) by January 23, 2013. Additional information will be posted when available or may be requested in hardcopy, see FOR FURTHER INFORMATION CONTACT. Following the meeting, a report of the peer review will be prepared and made available on the NTP Web site. Registered attendees are PO 00000 Frm 00044 Fmt 4703 Sfmt 4703 encouraged to access the meeting Web page to stay abreast of the most current information regarding the meeting. Request for Comments: The NTP invites written and oral public comments on the draft monographs. The deadline for submission of written comments is March 7, 2013, to enable review by the peer review panel and NTP staff prior to the meeting. Preregistration to provide oral comments is by March 19, 2013, at http:// ntp.niehs.nih.gov/go/36639. Public comments and any other correspondence on the draft monographs should be sent to the FOR FURTHER INFORMATION CONTACT. Persons submitting written comments should include their name, affiliation, mailing address, phone, email, and sponsoring organization (if any) with the document. Written comments received in response to this notice will be posted on the NTP Web site, and the submitter will be identified by name, affiliation, and/or sponsoring organization. Public comment at this meeting is welcome, with time set aside for the presentation of oral comments on the draft monographs. In addition to inperson oral comments at the meeting at the NIEHS, public comments can be presented by teleconference line. There will be 50 lines for this call; availability will be on a first-come, first-served basis. The lines will be open from 1:00 p.m. until approximately 5:00 p.m. EDT on March 21 and from 8:30 a.m. EDT until adjournment on March 22, although oral comments will be received only during the formal public comment periods indicated on the preliminary agenda. Each organization is allowed one time slot. At least 7 minutes will be allotted to each speaker, and if time permits, may be extended to 10 minutes at the discretion of the chair. Persons wishing to make an oral presentation are asked to register online at http://ntp.niehs.nih.gov/go/36639 by March 19, 2013, and if possible, to send a copy of their slides and/or statement or talking points at that time. Written statements can supplement and may expand the oral presentation. Registration for oral comments will also be available at the meeting, although time allowed for presentation by on-site registrants may be less than that for preregistered speakers and will be determined by the number of speakers who register on-site. Background Information on the RoC: Published biennially, each edition of the RoC is cumulative and consists of substances newly reviewed in addition to those listed in previous editions. The 12th RoC, the latest edition, was published on June 10, 2011 (available at E:\FR\FM\22JAN1.SGM 22JAN1 Federal Register / Vol. 78, No. 14 / Tuesday, January 22, 2013 / Notices http://ntp.niehs.nih.gov/go/roc12). The 13th RoC is under development. For each listed substance, the RoC contains a substance profile, which provides information on: Cancer studies that support the listing—including those in humans, animals, and studies on possible mechanisms of action— information about potential sources of exposure to humans, and current Federal regulations to limit exposures. Background Information on NTP Peer Review Panels: NTP panels are technical, scientific advisory bodies established on an ‘‘as needed’’ basis to provide independent scientific peer review and advise the NTP on agents of public health concern, new/revised toxicological test methods, or other issues. These panels help ensure transparent, unbiased, and scientifically rigorous input to the program for its use in making credible decisions about human hazard, setting research and testing priorities, and providing information to regulatory agencies about alternative methods for toxicity screening. The NTP welcomes nominations of scientific experts for upcoming panels. Scientists interested in serving on an NTP panel should provide a current curriculum vitae to the FOR FURTHER INFORMATION CONTACT. The authority for NTP panels is provided by 42 U.S.C. 217a; section 222 of the Public Health Service (PHS) Act, as amended. The panel is governed by the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), which sets forth standards for the formation and use of advisory committees. Dated: January 16, 2013. John R. Bucher, Associate Director, National Toxicology Program. [FR Doc. 2013–01242 Filed 1–18–13; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES tkelley on DSK3SPTVN1PROD with National Institute on Drug Abuse; Notice of Closed Meetings [FR Doc. 2013–01100 Filed 1–18–13; 8:45 am] BILLING CODE 4140–01–P Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The contract proposals and the discussions could disclose confidential trade secrets or commercial property such as patentable materials, 18:11 Jan 18, 2013 Jkt 229001 Name of Committee: National Institute on Drug Abuse Special Emphasis Panel; Development of Predictive In vivo Screening Systems for Phenotypic Drug Discovery (7786). Date: January 25, 2013. Time: 1:00 p.m. to 3:30 p.m. Agenda: To review and evaluate contract proposals. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Gerald L. McLaughlin, Ph.D., Scientific Review Officer, Office of Extramural Affairs, National Institute on Drug Abuse, NIH, DHHS, 6001 Executive Blvd., Room 4238, MSC 9550, Bethesda, MD 20892–9550, 301–402–6626, gm145a@nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. Name of Committee: National Institute on Drug Abuse Special Emphasis Panel; SBIR Topic 148 Review Meeting (4418) Date: January 30, 2013. Time: 8:30 a.m. to 3:00 p.m. Agenda: To review and evaluate contract proposals. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852, Contact Person: Jose F. Ruiz, Ph.D., Scientific Review Officer, Office of Extramural Affairs, National Institute on Drug Abuse, NIH, Room 4228, MSC 9550, 6001 Executive Blvd., Bethesda, MD 20892– 9550, (301) 451–3086, ruizjf@nida.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs, National Institutes of Health, HHS) Dated: January 15, 2013. Michelle Trout, Program Analyst, Office of Federal Advisory Committee Policy. National Institutes of Health VerDate Mar<15>2010 and personal information concerning individuals associated with the contract proposals, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for Advancing Translational Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as PO 00000 Frm 00045 Fmt 4703 Sfmt 4703 4421 amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The contract and grant proposals and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the contract proposals, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Center for Advancing Translational Sciences Special Emphasis Panel; Therapeutics Discovery. Date: February 13–14, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health/ NCATS/OR, Democracy 1, Room 1080, 6701 Democracy Blvd., Bethesda, MD 20892, (Virtual Meeting). Contact Person: Barbara J. Nelson, Ph.D., Scientific Review Officer, Office of Grants Management & Scientific Review, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 6701 Democracy Blvd., Room 1080, 1 Dem. Plaza, Bethesda, MD 20892–4874, 301–435–0806, nelsonbj@mail.nih.gov. Name of Committee: National Center for Advancing Translational Sciences Special Emphasis Panel; TRND–1. Date: February 28–March 1, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate contract proposals. Place: Bethesda North Marriott Hotel & Conference Center, Montgomery County Conference Center Facility, 5701 Marinelli Road, North Bethesda, MD 20852. Contact Person: Guo He Zhang, Ph.D., MPH, Scientific Review Officer, Office of Grants Management & Scientific Review, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 6701 Democracy Blvd., Democracy 1, Room 1064, Bethesda, MD 20892–4874, 301– 435–0812, zhanggu@mail.nih.gov. Name of Committee: National Center for Advancing Translational Sciences Special Emphasis Panel; TRND–3. Date: March 13–14, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: Gaithersburg Marriott Washingtonian Center, 9751 Washingtonian Boulevard, Gaithersburg, MD 20878. Contact Person: Sheri A. Hild, Scientific Review Officer, Office of Grants Management & Scientific Review, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 6701 Democracy Blvd., Democracy 1, Room 1082, Bethesda, MD 20892–4874, 301–435–0811, hildsa@mail.nih.gov. E:\FR\FM\22JAN1.SGM 22JAN1

Agencies

[Federal Register Volume 78, Number 14 (Tuesday, January 22, 2013)]
[Notices]
[Pages 4419-4421]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2013-01242]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Draft Report on Carcinogens Monographs for 1-Bromopropane and 
Cumene; Availability of Documents; Request for Comments; Notice of 
Meeting

SUMMARY: Peer review meeting of the Draft Report on Carcinogens (RoC) 
Monographs for 1-Bromopropane and Cumene. These documents were prepared 
by the Office of the Report on Carcinogens (ORoC), Division of the 
National Toxicology Program (DNTP), National Institute of Environmental 
Health Sciences (NIEHS).

DATES: Meeting: March 21, 2013, 1:00 p.m. to approximately 5:00 p.m. 
Eastern Daylight Time (EDT) and March 22, 2013, from 8:30 a.m. until 
adjournment, approximately 2:00 p.m. EDT.
    Document Availability: Draft monographs will be available by 
January

[[Page 4420]]

23, 2013, at http://ntp.niehs.nih.gov/go/36639.
    Public Comments Submissions: Deadline is March 7, 2013.
    Pre-Registration for Meeting and/or Oral Comments: Deadline is 
March 19, 2013.

ADDRESSES: Meeting Location: NIEHS, Keystone Building, Room 1003AB, 530 
Davis Drive, Morrisville, NC 27560.
    Agency Meeting Web page: The draft monographs, draft agenda, 
registration and other meeting materials are at http://ntp.niehs.nih.gov/go/36639.
    Webcast: The meeting will be available via webcast at http://www.niehs.nih.gov/news/video/index.cfm.

FOR FURTHER INFORMATION CONTACT: Dr. Lori D. White, NTP Designated 
Federal Official, Office of Liaison, Policy and Review, DNTP, NIEHS, 
P.O. Box 12233, MD K2-03, Research Triangle Park, NC 27709. Phone: 
(919) 541-9834, Fax: (301) 480-3272, Email: whiteld@niehs.nih.gov. Hand 
Delivery/Courier: 530 Davis Drive, Room 2136, Morrisville, NC 27560.

SUPPLEMENTARY INFORMATION: Background: The Report on Carcinogens (RoC) 
is a congressionally mandated, science-based, public health report that 
identifies agents, substances, mixtures, or exposures (collectively 
called ``substances'') in our environment that may put people in the 
United States at increased risk for cancer. The NTP prepares the RoC on 
behalf of the Secretary of Health and Human Services.
    The NTP follows an established, four-part process for preparation 
of the RoC (http://ntp.niehs.nih.gov/go/rocprocess). A RoC Monograph is 
prepared for each candidate substance selected for review for the RoC. 
1-Bromopropane and cumene were selected as candidate substances 
following solicitation of public comment and review by the NTP Board of 
Scientific Counselors review on June 21-22, 2012 (http://ntp.niehs.nih.gov/go/9741). A draft RoC monograph consists of a (1) 
cancer evaluation component that reviews all information that may bear 
on a listing decision, assesses its quality and sufficiency for 
reaching a listing decision, applies the RoC listing criteria to the 
relevant scientific information, and recommends a listing status for 
the candidate substance in the RoC and (2) a substance profile that 
contains the NTP's preliminary listing recommendation and a summary of 
the scientific evidence considered key to reaching that recommendation. 
This meeting is planned for peer review of the draft RoC Monographs for 
1-bromopropane and cumene.
    1-Bromopropane (CASRN 106-94-5) is a brominated hydrocarbon that is 
currently used as a solvent in a variety of industrial and commercial 
applications. It is used as a solvent cleaner to degrease electronics, 
precision optics, and metals, as a solvent vehicle in industries that 
use aerosolized adhesives (e.g., foam cushion manufacturing), as a spot 
remover in the textile industry, and as a solvent in the dry cleaning 
industry. Additional information about the review of 1-bromopropane for 
the RoC is available at http://ntp.niehs.nih.gov/go/37896.
    Cumene (CASRN 98-82-8, isopropylbenzene) is an alkylated benzene 
found in fossil fuels, such as blended gasoline and kerosene, and 
products of incomplete combustion. It is a high production volume 
chemical in the United States with the majority of its use in the 
synthesis of acetone and phenol. Additional information about the 
review of cumene for the RoC is available at http://ntp.niehs.nih.gov/go/37895.
    Meeting and Registration: The meeting is open to the public with 
time set aside for oral public comment; attendance at the NIEHS is 
limited only by the space available. The meeting is scheduled for March 
21, 2013, 1:00 p.m. to approximately 5:00 p.m. EDT and March 22, 2013, 
from 8:30 a.m. until adjournment, approximately 2:00 p.m. EDT. Two days 
are set aside for the meeting; however, it may adjourn sooner if the 
panel completes its peer review of the draft monographs. Pre-
registration to attend the meeting and/or provide oral comments is by 
March 19, 2013, at http://ntp.niehs.nih.gov/go/36639. Visitor and 
security information is available at http://www.niehs.nih.gov/about/visiting/index.cfm. Individuals with disabilities who need 
accommodation to participate in this event should contact Danica 
Andrews at phone: (919) 541-2595 or email: andrewsda@niehs.nih.gov. TTY 
users should contact the Federal TTY Relay Service at (800) 877-8339. 
Requests should be made at least five business days in advance of the 
event.
    The preliminary agenda and draft monographs should be posted on the 
NTP Web site (http://ntp.niehs.nih.gov/go/36639) by January 23, 2013. 
Additional information will be posted when available or may be 
requested in hardcopy, see FOR FURTHER INFORMATION CONTACT. Following 
the meeting, a report of the peer review will be prepared and made 
available on the NTP Web site. Registered attendees are encouraged to 
access the meeting Web page to stay abreast of the most current 
information regarding the meeting.
    Request for Comments: The NTP invites written and oral public 
comments on the draft monographs. The deadline for submission of 
written comments is March 7, 2013, to enable review by the peer review 
panel and NTP staff prior to the meeting. Pre-registration to provide 
oral comments is by March 19, 2013, at http://ntp.niehs.nih.gov/go/36639. Public comments and any other correspondence on the draft 
monographs should be sent to the FOR FURTHER INFORMATION CONTACT. 
Persons submitting written comments should include their name, 
affiliation, mailing address, phone, email, and sponsoring organization 
(if any) with the document. Written comments received in response to 
this notice will be posted on the NTP Web site, and the submitter will 
be identified by name, affiliation, and/or sponsoring organization.
    Public comment at this meeting is welcome, with time set aside for 
the presentation of oral comments on the draft monographs. In addition 
to in-person oral comments at the meeting at the NIEHS, public comments 
can be presented by teleconference line. There will be 50 lines for 
this call; availability will be on a first-come, first-served basis. 
The lines will be open from 1:00 p.m. until approximately 5:00 p.m. EDT 
on March 21 and from 8:30 a.m. EDT until adjournment on March 22, 
although oral comments will be received only during the formal public 
comment periods indicated on the preliminary agenda. Each organization 
is allowed one time slot. At least 7 minutes will be allotted to each 
speaker, and if time permits, may be extended to 10 minutes at the 
discretion of the chair. Persons wishing to make an oral presentation 
are asked to register online at http://ntp.niehs.nih.gov/go/36639 by 
March 19, 2013, and if possible, to send a copy of their slides and/or 
statement or talking points at that time. Written statements can 
supplement and may expand the oral presentation. Registration for oral 
comments will also be available at the meeting, although time allowed 
for presentation by on-site registrants may be less than that for pre-
registered speakers and will be determined by the number of speakers 
who register on-site.
    Background Information on the RoC: Published biennially, each 
edition of the RoC is cumulative and consists of substances newly 
reviewed in addition to those listed in previous editions. The 12th 
RoC, the latest edition, was published on June 10, 2011 (available at

[[Page 4421]]

http://ntp.niehs.nih.gov/go/roc12). The 13th RoC is under development. 
For each listed substance, the RoC contains a substance profile, which 
provides information on: Cancer studies that support the listing--
including those in humans, animals, and studies on possible mechanisms 
of action--information about potential sources of exposure to humans, 
and current Federal regulations to limit exposures.
    Background Information on NTP Peer Review Panels: NTP panels are 
technical, scientific advisory bodies established on an ``as needed'' 
basis to provide independent scientific peer review and advise the NTP 
on agents of public health concern, new/revised toxicological test 
methods, or other issues. These panels help ensure transparent, 
unbiased, and scientifically rigorous input to the program for its use 
in making credible decisions about human hazard, setting research and 
testing priorities, and providing information to regulatory agencies 
about alternative methods for toxicity screening. The NTP welcomes 
nominations of scientific experts for upcoming panels. Scientists 
interested in serving on an NTP panel should provide a current 
curriculum vitae to the FOR FURTHER INFORMATION CONTACT. The authority 
for NTP panels is provided by 42 U.S.C. 217a; section 222 of the Public 
Health Service (PHS) Act, as amended. The panel is governed by the 
Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), which 
sets forth standards for the formation and use of advisory committees.

    Dated: January 16, 2013.
John R. Bucher,
Associate Director, National Toxicology Program.
[FR Doc. 2013-01242 Filed 1-18-13; 8:45 am]
BILLING CODE 4140-01-P