Amendment of Class D and Class E Airspace; Twentynine Palms, CA, 4306-4307 [2013-01071]
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4306
Federal Register / Vol. 78, No. 14 / Tuesday, January 22, 2013 / Rules and Regulations
DEPARTMENT OF TRANSPORTATION
Federal Aviation Administration
14 CFR Part 71
[Docket FAA No. FAA–2012–1253; Airspace
Docket No. 12–AWP–10]
Amendment of Class D and Class E
Airspace; Twentynine Palms, CA
Federal Aviation
Administration (FAA), DOT.
ACTION: Final rule; technical
amendment.
AGENCY:
This action amends Class D
and Class E airspace at Twentynine
Palms SELF Airport, Twentynine Palms,
CA. This action changes the airport
name formerly called Twentynine Palms
Expeditionary Air Field (EAF), Marine
Corps Base. This action also adjusts the
geographic coordinates of the airport to
enhance the safety and management of
aircraft operations at Twentynine Palms
SELF Airport, Twentynine Palms, CA.
This action does not change the
boundaries of the airspace.
DATES: Effective date, 0901 UTC, March
7, 2013. The Director of the Federal
Register approves this incorporation by
reference action under 1 CFR Part 51,
subject to the annual revision of FAA
Order 7400.9 and publication of
conforming amendments.
FOR FURTHER INFORMATION CONTACT:
Eldon Taylor, Federal Aviation
Administration, Operations Support
Group, Western Service Center, 1601
Lind Avenue SW., Renton, WA 98057;
telephone (425) 203–4537.
SUPPLEMENTARY INFORMATION:
SUMMARY:
tkelley on DSK3SPTVN1PROD with
History
The FAA’s Aeronautical Products
Office requested the change to the
airport name and geographic
coordinates of Twentynine Palms SELF
Airport, Twentynine Palms, CA.
The Class D airspace and Class E
airspace designations are published in
paragraphs 5000 and 6004, respectively,
of FAA Order 7400.9W, dated August 8,
2012, and effective September 15, 2012,
which is incorporated by reference in 14
CFR 71.1. The Class D airspace and
Class E airspace designation listed in
this document will be published
subsequently in the Order.
The Rule
The FAA amends Title 14 Code of
Federal Regulations (14 CFR) Part 71 by
changing the airport name described in
Class D airspace and Class E airspace
designated as an extension to Class D
surface area at Twentynine Palms, CA,
to Twentynine Palms SELF Airport,
VerDate Mar<15>2010
17:36 Jan 18, 2013
Jkt 229001
formerly Twentynine Palms
Expeditionary Air Field (EAF), Marine
Corps Base. The geographic coordinates
of the airport are also adjusted to be in
accordance with the FAA’s aeronautical
database. Accordingly, since this is an
administrative change and does not
involve a change in the dimensions or
operation requirements of that airspace,
notice and public procedures under 5
U.S.C. 553(b) are unnecessary.
The FAA has determined this
regulation only involves an established
body of technical regulations for which
frequent and routine amendments are
necessary to keep them operationally
current. Therefore, this regulation; (1) Is
not a ‘‘significant regulatory action’’
under Executive Order 12866; (2) is not
a ‘‘significant rule’’ under DOT
Regulatory Policies and Procedures (44
FR 11034; February 26, 1979); and (3)
does not warrant preparation of a
regulatory evaluation as the anticipated
impact is so minimal. Since this is a
routine matter that will only affect air
traffic procedures and air navigation, it
is certified this rule, when promulgated,
will not have a significant economic
impact on a substantial number of small
entities under the criteria of the
Regulatory Flexibility Act.
The FAA’s authority to issue rules
regarding aviation safety is found in
Title 49 of the U.S. Code. Subtitle 1,
Section 106, describes the authority for
the FAA Administrator. Subtitle VII,
Aviation Programs, describes in more
detail the scope of the agency’s
authority. This rulemaking is
promulgated under the authority
described in Subtitle VII, Part A,
Subpart I, Section 40103. Under that
section, the FAA is charged with
prescribing regulations to assign the use
of the airspace necessary to ensure the
safety of aircraft and the efficient use of
airspace. This regulation is within the
scope of that authority as it amends
controlled airspace at Twentynine
Palms SELF Airport, Twentynine Palms,
CA.
Environmental Review
The FAA has determined that this
action qualifies for categorical exclusion
under the National Environmental
Policy Act in accordance with FAA
Order 1050.1E, ‘‘Environmental
Impacts: Policies and Procedures,’’
paragraph 311a. This airspace action is
not expected to cause any potentially
significant environmental impacts, and
no extraordinary circumstances exist
that warrant preparation of an
environmental assessment.
PO 00000
Frm 00002
Fmt 4700
Sfmt 4700
Lists of Subjects in 14 CFR Part 71
Airspace, Incorporation by reference,
Navigation (air).
Adoption of the Amendment
In consideration of the foregoing, the
Federal Aviation Administration
amends 14 CFR part 71 as follows:
PART 71—DESIGNATION OF CLASS A,
B, C, D AND E AIRSPACE AREAS; AIR
TRAFFIC SERVICE ROUTES; AND
REPORTING POINTS
1. The authority citation for part 71
continues to read as follows:
■
Authority: 49 U.S.C. 106(g); 40103, 40113,
40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959–
1963 Comp., p. 389.
§ 71.1
[Amended]
2. The incorporation by reference in
14 CFR 71.1 of Federal Aviation
Administration Order 7400.9W,
Airspace Designations and Reporting
Points, dated August 8, 2012, and
effective September 15, 2012, is
amended as follows:
■
Paragraph 5000
Class D airspace.
*
*
*
*
*
AWP CA D Twentynine Palms, CA
[Amended]
Twentynine Palms SELF Airport, CA
(Lat. 34°17′46″ N., long. 116°09′44″ W.)
That airspace extending upward from the
surface to and including 4,600 feet MSL
within a 4.3-mile radius of the Twentynine
Palms SELF Airport. This Class D airspace
area is effective during the specific dates and
times established in advance by a Notice to
Airmen. The effective date and time will
thereafter be continuously published in the
Airport/Facility Directory.
Paragraph 6004 Class E airspace designated
as an extension to a Class D surface area.
*
*
*
AWP CA E4
[Amended]
*
*
Twentynine Palms, CA
Twentynine Palms SELF Airport, CA
(Lat. 34°17′46″ N., long. 116°09′44″ W.)
Twentynine Palms VORTAC
(Lat. 34°06′44″ N., long. 115°46′12″ W.)
That airspace extending upward from the
surface within 1.8 miles each side of the
Twentynine Palms VORTAC 298° radial
extending from the 4.3-mile radius of
Twentynine Palms SELF Airport to 13.9
miles west of the VORTAC. This Class E
airspace area is effective during the specific
dates and times established in advance by a
Notice to Airmen. The effective date and time
will thereafter be continuously published in
the Airport/Facility Directory.
E:\FR\FM\22JAR1.SGM
22JAR1
Federal Register / Vol. 78, No. 14 / Tuesday, January 22, 2013 / Rules and Regulations
Issued in Seattle, Washington, on
December 19, 2012.
Clark Desing,
Manager, Operations Support Group, Western
Service Center.
[FR Doc. 2013–01071 Filed 1–18–13; 8:45 am]
BILLING CODE 4910–13–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
21 CFR Part 4
[Docket No. FDA–2009–N–0435]
Current Good Manufacturing Practice
Requirements for Combination
Products
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Final rule.
The Food and Drug
Administration (FDA or Agency) is
issuing this regulation on the current
good manufacturing practice (CGMP)
requirements applicable to combination
products. This rule is intended to
promote the public health by clarifying
which CGMP requirements apply when
drugs, devices, and biological products
are combined to create combination
products. In addition, the rule sets forth
a transparent and streamlined regulatory
framework for firms to use when
demonstrating compliance with CGMP
requirements for ‘‘single-entity’’ and
‘‘co-packaged’’ combination products.
DATES: This rule is effective July 22,
2013.
FOR FURTHER INFORMATION CONTACT: John
Barlow Weiner, Office of Combination
Products, Food and Drug
Administration, 10903 New Hampshire
Ave., Bldg. 32, Rm. 5130, Silver Spring,
MD 20993, 301–796–8930.
SUPPLEMENTARY INFORMATION:
SUMMARY:
tkelley on DSK3SPTVN1PROD with
Table of Contents
I. Background
A. Rationale for the Rulemaking
B. The Proposed Rule
C. The Final Rule
II. Comments on the Proposed Rule
A. General
B. What is the scope of this subpart? (§ 4.1)
C. How does FDA define key terms and
phrases in this subpart? (§ 4.2)
D. What current good manufacturing
practice requirements apply to my
combination product? (§ 4.3)
E. How can I comply with these current
good manufacturing practice
requirements for a co-packaged or singleentity combination product? (§ 4.4)
E.1. How To Comply With QS Regulation
Requirements Under § 4.4(b)(1)
VerDate Mar<15>2010
17:36 Jan 18, 2013
Jkt 229001
E.2. How To Comply With Drug CGMP
Requirements Under § 4.4(b)(2)
E.3. How To Comply With Biological
Product and HCT/P Requirements Under
§ 4.4(b)(3)
F. Enforcement and Effective Date
G. Alternate Approaches
H. Guidance
I. Other
III. Legal Authority
IV. Analysis of Economic Impacts
A. Introduction
B. Rationale for Final Rule
C. Response to Comments
D. Impact of Final Rule
V. Environmental Impact
VI. Paperwork Reduction Act of 1995
VII. Executive Order 13132: Federalism
I. Background
A. Rationale for the Rulemaking
As set forth in part 3 (21 CFR part 3),
a combination product is a product
comprised of any combination of a drug
and a device; a device and a biological
product; a biological product and a
drug; or a drug, a device, and a
biological product.1 Under § 3.2(e), a
combination product includes:
1. A product comprised of two or
more regulated components, i.e., drug/
device, biologic/device, drug/biologic,
or drug/device/biologic, that are
physically, chemically, or otherwise
combined or mixed and produced as a
single entity (single-entity combination
products);
2. Two or more separate products
packaged together in a single package or
as a unit and comprised of drug and
device products, device and biological
products, or biological and drug
products (co-packaged combination
products);
3. A drug, device, or biological
product packaged separately that
according to its investigational plan or
proposed labeling is intended for use
only with an approved individually
specified drug, device, or biological
product where both are required to
achieve the intended use, indication, or
effect and where upon approval of the
proposed product the labeling of the
approved product would need to be
changed, e.g., to reflect a change in
intended use, dosage form, strength,
route of administration, or significant
change in dose (a type of cross-labeled
combination product); or
4. Any investigational drug, device, or
biological product packaged separately
that according to its proposed labeling
1 For purposes of part 3 and this rule, a
‘‘biological product’’’ means a biological product
subject to regulation under section 351 of the Public
Health Service Act (the PHS Act) (42 U.S.C. 262).
All biological products regulated under the PHS Act
meet the definitions of drug or device in section 201
of the Federal Food, Drug, and Cosmetic Act (the
FD&C Act) (21 U.S.C. 321).
PO 00000
Frm 00003
Fmt 4700
Sfmt 4700
4307
is for use only with another individually
specified investigational drug, device, or
biological product where both are
required to achieve the intended use,
indication, or effect (another type of
cross-labeled combination product).
The constituent parts of a
combination product retain their
regulatory status (as a drug or device, for
example) after they are combined.
Accordingly, the CGMP requirements
that apply to each of the constituent
parts continue to apply when they are
combined to make combination
products.2 To date, however, the
Agency has not issued specific
regulations clarifying the applicability
of the CGMP requirements to
combination products. While CGMP
regulations are in place that establish
requirements for drugs, devices, and
biological products, there are currently
no regulations that clarify and explain
the application of these CGMP
requirements when these drugs, devices,
and biological products are constituent
parts of a combination product. FDA
believes that the absence of clear CGMP
requirements for combination products
could result in inconsistent or differing
application of the various CGMP
requirements applicable to the
constituent parts, which could affect
product safety and the public health. In
addition, the absence of clear
requirements could lead some
manufacturers to develop and document
manufacturing practices that are
redundant and overly burdensome.
In the Federal Register of October 4,
2004 (69 FR 59239), the Agency
announced the availability of a Draft
Guidance for Industry and FDA entitled
‘‘Current Good Manufacturing Practices
for Combination Products.’’ The Agency
received 15 comments, which were
largely supportive of the regulatory
approach described in the draft
guidance. A common theme that
emerged from these comments was the
need to develop a clear regulatory
framework that takes account of the fact
that combination products are made up
of drug, device, and biological product
constituent parts. At the same time,
commenters wanted to ensure that the
framework would not lead to
unnecessary redundancy in the
operating systems used to meet CGMP
2 Section 501 of the FD&C Act (21 U.S.C. 351)
states circumstances under which drugs and
devices (including biological products, which also
meet the definition of either drug or device) are
deemed adulterated. Adulteration includes the
failure to manufacture a product in accordance with
applicable CGMP requirements, regardless of
whether the product appears to meet its final
specifications. See, generally, 21 U.S.C. 351(a)(2)(B)
and (h).
E:\FR\FM\22JAR1.SGM
22JAR1
Agencies
[Federal Register Volume 78, Number 14 (Tuesday, January 22, 2013)]
[Rules and Regulations]
[Pages 4306-4307]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2013-01071]
[[Page 4306]]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF TRANSPORTATION
Federal Aviation Administration
14 CFR Part 71
[Docket FAA No. FAA-2012-1253; Airspace Docket No. 12-AWP-10]
Amendment of Class D and Class E Airspace; Twentynine Palms, CA
AGENCY: Federal Aviation Administration (FAA), DOT.
ACTION: Final rule; technical amendment.
-----------------------------------------------------------------------
SUMMARY: This action amends Class D and Class E airspace at Twentynine
Palms SELF Airport, Twentynine Palms, CA. This action changes the
airport name formerly called Twentynine Palms Expeditionary Air Field
(EAF), Marine Corps Base. This action also adjusts the geographic
coordinates of the airport to enhance the safety and management of
aircraft operations at Twentynine Palms SELF Airport, Twentynine Palms,
CA. This action does not change the boundaries of the airspace.
DATES: Effective date, 0901 UTC, March 7, 2013. The Director of the
Federal Register approves this incorporation by reference action under
1 CFR Part 51, subject to the annual revision of FAA Order 7400.9 and
publication of conforming amendments.
FOR FURTHER INFORMATION CONTACT: Eldon Taylor, Federal Aviation
Administration, Operations Support Group, Western Service Center, 1601
Lind Avenue SW., Renton, WA 98057; telephone (425) 203-4537.
SUPPLEMENTARY INFORMATION:
History
The FAA's Aeronautical Products Office requested the change to the
airport name and geographic coordinates of Twentynine Palms SELF
Airport, Twentynine Palms, CA.
The Class D airspace and Class E airspace designations are
published in paragraphs 5000 and 6004, respectively, of FAA Order
7400.9W, dated August 8, 2012, and effective September 15, 2012, which
is incorporated by reference in 14 CFR 71.1. The Class D airspace and
Class E airspace designation listed in this document will be published
subsequently in the Order.
The Rule
The FAA amends Title 14 Code of Federal Regulations (14 CFR) Part
71 by changing the airport name described in Class D airspace and Class
E airspace designated as an extension to Class D surface area at
Twentynine Palms, CA, to Twentynine Palms SELF Airport, formerly
Twentynine Palms Expeditionary Air Field (EAF), Marine Corps Base. The
geographic coordinates of the airport are also adjusted to be in
accordance with the FAA's aeronautical database. Accordingly, since
this is an administrative change and does not involve a change in the
dimensions or operation requirements of that airspace, notice and
public procedures under 5 U.S.C. 553(b) are unnecessary.
The FAA has determined this regulation only involves an established
body of technical regulations for which frequent and routine amendments
are necessary to keep them operationally current. Therefore, this
regulation; (1) Is not a ``significant regulatory action'' under
Executive Order 12866; (2) is not a ``significant rule'' under DOT
Regulatory Policies and Procedures (44 FR 11034; February 26, 1979);
and (3) does not warrant preparation of a regulatory evaluation as the
anticipated impact is so minimal. Since this is a routine matter that
will only affect air traffic procedures and air navigation, it is
certified this rule, when promulgated, will not have a significant
economic impact on a substantial number of small entities under the
criteria of the Regulatory Flexibility Act.
The FAA's authority to issue rules regarding aviation safety is
found in Title 49 of the U.S. Code. Subtitle 1, Section 106, describes
the authority for the FAA Administrator. Subtitle VII, Aviation
Programs, describes in more detail the scope of the agency's authority.
This rulemaking is promulgated under the authority described in
Subtitle VII, Part A, Subpart I, Section 40103. Under that section, the
FAA is charged with prescribing regulations to assign the use of the
airspace necessary to ensure the safety of aircraft and the efficient
use of airspace. This regulation is within the scope of that authority
as it amends controlled airspace at Twentynine Palms SELF Airport,
Twentynine Palms, CA.
Environmental Review
The FAA has determined that this action qualifies for categorical
exclusion under the National Environmental Policy Act in accordance
with FAA Order 1050.1E, ``Environmental Impacts: Policies and
Procedures,'' paragraph 311a. This airspace action is not expected to
cause any potentially significant environmental impacts, and no
extraordinary circumstances exist that warrant preparation of an
environmental assessment.
Lists of Subjects in 14 CFR Part 71
Airspace, Incorporation by reference, Navigation (air).
Adoption of the Amendment
In consideration of the foregoing, the Federal Aviation
Administration amends 14 CFR part 71 as follows:
PART 71--DESIGNATION OF CLASS A, B, C, D AND E AIRSPACE AREAS; AIR
TRAFFIC SERVICE ROUTES; AND REPORTING POINTS
0
1. The authority citation for part 71 continues to read as follows:
Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854,
24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389.
Sec. 71.1 [Amended]
0
2. The incorporation by reference in 14 CFR 71.1 of Federal Aviation
Administration Order 7400.9W, Airspace Designations and Reporting
Points, dated August 8, 2012, and effective September 15, 2012, is
amended as follows:
Paragraph 5000 Class D airspace.
* * * * *
AWP CA D Twentynine Palms, CA [Amended]
Twentynine Palms SELF Airport, CA
(Lat. 34[deg]17'46'' N., long. 116[deg]09'44'' W.)
That airspace extending upward from the surface to and including
4,600 feet MSL within a 4.3-mile radius of the Twentynine Palms SELF
Airport. This Class D airspace area is effective during the specific
dates and times established in advance by a Notice to Airmen. The
effective date and time will thereafter be continuously published in
the Airport/Facility Directory.
Paragraph 6004 Class E airspace designated as an extension to a
Class D surface area.
* * * * *
AWP CA E4 Twentynine Palms, CA [Amended]
Twentynine Palms SELF Airport, CA
(Lat. 34[deg]17'46'' N., long. 116[deg]09'44'' W.)
Twentynine Palms VORTAC
(Lat. 34[deg]06'44'' N., long. 115[deg]46'12'' W.)
That airspace extending upward from the surface within 1.8 miles
each side of the Twentynine Palms VORTAC 298[deg] radial extending
from the 4.3-mile radius of Twentynine Palms SELF Airport to 13.9
miles west of the VORTAC. This Class E airspace area is effective
during the specific dates and times established in advance by a
Notice to Airmen. The effective date and time will thereafter be
continuously published in the Airport/Facility Directory.
[[Page 4307]]
Issued in Seattle, Washington, on December 19, 2012.
Clark Desing,
Manager, Operations Support Group, Western Service Center.
[FR Doc. 2013-01071 Filed 1-18-13; 8:45 am]
BILLING CODE 4910-13-P