Report on Carcinogens Evaluation of Pentachlorophenol; Request for Nominations of Scientific Experts, 63848-63849 [2012-25472]

Download as PDF mstockstill on DSK4VPTVN1PROD with NOTICES 63848 Federal Register / Vol. 77, No. 201 / Wednesday, October 17, 2012 / Notices Boulevard, Rockville, MD 20852, (Telephone Conference Call). Contact Person: Vinod Charles, Ph.D., Scientific Review Officer, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6151, MSC 9606, Bethesda, MD 20892–9606, 301–443–1606, charlesvi@mail.nih.gov. Name of Committee: National Institute of Mental Health Special Emphasis Panel; PreDoctoral/Post-Doctoral Fellowships. Date: November 7, 2012. Time: 12:00 p.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852, (Telephone Conference Call). Contact Person: David M. Armstrong, Ph.D., Scientific Review Officer, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center/ Room 6138/MSC 9608, 6001 Executive Boulevard, Bethesda, MD 20892–9608, 301– 443–3534, armstrda@mail.nih.gov. Name of Committee: National Institute of Mental Health Special Emphasis Panel; ITVA/ITVC Conflicts. Date: November 8, 2012. Time: 3:30 p.m. to 5:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852, (Telephone Conference Call). Contact Person: Vinod Charles, Ph.D., Scientific Review Officer, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6151, MSC 9606, Bethesda, MD 20892–9606, 301–443–1606, charlesvi@mail.nih.gov. Name of Committee: National Institute of Mental Health Special Emphasis Panel; Grand Challenges in Global Mental Health. Date: November 8, 2012. Time: 12:00 p.m. to 5:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852, (Telephone Conference Call). Contact Person: Marina Broitman, Ph.D., Scientific Review Officer, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6153, MSC 9608, Bethesda, MD 20892–9608, 301–402–8152, mbroitma@mail.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.242, Mental Health Research Grants; 93.281, Scientist Development Award, Scientist Development Award for Clinicians, and Research Scientist Award; 93.282, Mental Health National Research Service Awards for Research Training, National Institutes of Health, HHS) VerDate Mar<15>2010 18:49 Oct 16, 2012 Jkt 229001 Dated: October 10, 2012. Carolyn A. Baum, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2012–25435 Filed 10–16–12; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Report on Carcinogens Evaluation of Pentachlorophenol; Request for Nominations of Scientific Experts The National Toxicology Program (NTP), Division of the National Toxicology Program (DNTP), National Institute of Environmental Health Sciences (NIEHS), is initiating development of the Report on Carcinogens (RoC) monograph on pentachlorophenol. To inform development of that monograph, the Office of the RoC (ORoC) will hold a web-based meeting to obtain information related to evaluating human epidemiologic studies on exposure to pentachlorophenol and cancer risk and invites the nomination of speakers. Nominees should have expertise in cancer epidemiology and knowledge of studies related to exposure to pentachlorophenol. Self-nomination is permitted. SUMMARY: The deadline for nominations is December 3, 2012. ADDRESSES: Nominations should be submitted to Dr. Ruth Lunn, Director, ORoC, DNTP, NIEHS, P.O. Box 12233, MD K2–14, Research Triangle Park, NC 27709; telephone (919) 316–4637; FAX: (301) 480–2970; lunn@niehs.nih.gov. Courier address: NIEHS, Room 2138, 530 Davis Drive, Morrisville, NC 27560. FOR FURTHER INFORMATION CONTACT: Dr. Ruth Lunn, Director, ORoC, DNTP, NIEHS, P.O. Box 12233, MD K2–14, Research Triangle Park, NC 27709; telephone (919) 316–4637; FAX: (301) 480–2970; lunn@niehs.nih.gov. Courier address: NIEHS, Room 2138, 530 Davis Drive, Morrisville, NC 27560. SUPPLEMENTARY INFORMATION: Background: Pentachlorophenol (including its sodium salts) is a chlorinated aromatic compound that is used primarily as a wood preservative in the United States. It was selected for evaluation for the RoC based on widespread past use and current exposure in the United States and an adequate database of cancer studies. The final concept document for pentachlorophenol, which outlines the rationale for its selection for RoC DATES: PO 00000 Frm 00063 Fmt 4703 Sfmt 4703 evaluation and the proposed approach for development of the cancer evaluation component of the RoC monograph on pentachlorophenol, is available on the RoC Web site ( https://ntp.niehs.nih.gov/go/37897). The NTP Board of Scientific Counselors provided comments on the draft concept at its meeting on June 21, 2012 (minutes available at https://ntp.niehs.nih.gov/go/ 9741). Important to the evaluation of the potential carcinogenicity of pentachlorophenol is the assessment of evidence from human cancer studies. From an initial search of the peerreviewed literature, the available human epidemiologic studies include: (1) Several case-control studies (primarily of hematopoietic cancer) reporting risk estimates for job titles associated with pentachlorophenol exposure or exposure to chlorophenols with limited information on exposure specific for pentachlorophenol, (2) case-control studies reporting risk estimates specific for pentachlorophenol, and (3) cohort studies of pentachlorophenol production workers or users. A key issue in evaluating the evidence in humans is the potential for confounding from co-exposures, especially contaminants of pentachlorophenol formed during its production. Major cancers of interest are multiple myeloma, lymphoma, and soft-tissue sarcoma. Meeting Information: ORoC will hold a web-based meeting to obtain information related to evaluating human epidemiologic studies on exposure to pentachlorophenol and cancer risk, especially for lymphoma and multiple myeloma. In planning for this event, ORoC is inviting the nomination of speakers who would make presentations that focus on the methods used in human epidemiologic studies of pentachlorophenol to evaluate potential confounding from occupational coexposures, other types of information that may be important in evaluating potential confounding, and how exposure to confounders may affect each study’s findings. Once plans for the web-based meeting are finalized, additional information including agenda, speakers, logistics, and registration, will be announced in a subsequent Federal Register notice. Request for Nominations of Speakers: ORoC invites the nomination of speakers for the web-based meeting with expertise in epidemiology and knowledge of cancer studies on exposure to pentachlorophenol. Selfnomination is permitted. Each nomination should include (1) Contact information for the nominee [name, E:\FR\FM\17OCN1.SGM 17OCN1 Federal Register / Vol. 77, No. 201 / Wednesday, October 17, 2012 / Notices affiliation (if any), address, telephone, fax, and email], (2) a short description of the individual’s expertise relative to the review of human epidemiologic studies of exposure to pentachlorophenol and cancer risk, (3) curriculum vitae, and (4) an abstract describing what would be covered in the talk to address the presentations’ focus as noted above in ‘‘Meeting Information.’’ Persons submitting nominations should provide their name, contact information, affiliation, and sponsoring organization (if any). Nominations should be submitted to Dr. Lunn (see ADDRESSES); their receipt will be acknowledged by email. The deadline for nominations is December 3, 2012. Persons selected as speakers will be notified by email at least 30 days prior to the meeting. Background Information on the RoC: The RoC is a congressionally mandated document that identifies and discusses substances that may pose a hazard to human health by virtue of their carcinogenicity. Substances are listed in the report as either known or reasonably anticipated human carcinogens. The NTP prepares the RoC on behalf of the Secretary of Health and Human Services following a formal, multi-step process for review and evaluation of selected substances (https://ntp.niehs.nih.gov/go/ rocprocess). Information about the RoC is available on the RoC Web site (https:// ntp.niehs.nih.gov/go/roc) or by contacting Dr. Lunn (see ADDRESSES). Dated: October 11, 2012. John R. Bucher, Associate Director, National Toxicology Program. [FR Doc. 2012–25472 Filed 10–16–12; 8:45 am] BILLING CODE 9110–04–P Coast Guard DEPARTMENT OF HOMELAND SECURITY [Docket No. USCG–2012–0908] Coast Guard Facility Security Officer Training Requirements; Correction [Docket No. USCG–2012–0855] Coast Guard, DHS. ACTION: Notice of public meeting; request for comments; correction. AGENCY: mstockstill on DSK4VPTVN1PROD with NOTICES In the notice of public meeting; request for public comments FR Doc. 2012–0908, beginning on page 61771, make the following correction. On page 61771, revise the last paragraph in the ADDRESSES section to read as follows: To RSVP for the meeting, fill out the RSVP form using the following link https://einvitations.afit.edu/inv/ anim.cfm?i=123867&k=036341017D50. [FR Doc. 2012–25571 Filed 10–16–12; 8:45 am] DEPARTMENT OF HOMELAND SECURITY National Offshore Safety Advisory Committee Jkt 229001 United States Coast Guard Committee Management; Notice of Federal Advisory Committee Meetings. AGENCY: The Coast Guard published a notice of public meeting; request for comments in the Federal Register on October 11, 2012 (77 FR 61771), announcing a public meeting to receive comments on the development of a Facility Security Officer training program. The notice contains an SUMMARY: 18:49 Oct 16, 2012 Correction Dated: October 11, 2012. Kathryn Sinniger, Chief, Office of Regulations and Administrative Law, U.S. Coast Guard. BILLING CODE 4140–01–P VerDate Mar<15>2010 inaccurate Internet link to RSVP for the public meeting. DATES: The notice of public meeting; request for comments published in the Federal Register on October 11, 2012 (77 FR 61771) is corrected as of October 17, 2012. FOR FURTHER INFORMATION CONTACT: If you have questions concerning the meeting or this notice, please call or email LTJG Lindsey Musselwhite, Commandant (CG–FAC–2), Coast Guard; telephone 202–372–1136, email Lindsey.A.Musselwhite@uscg.mil or ´ ´ LCDR Jose Ramırez, Commandant (CG– FAC–2), Coast Guard; telephone 202– 372–1150, email Jose.L.Ramirez@uscg.mil. If you have questions on viewing or submitting material to the docket, call Ms. Renee V. Wright, Program Manager, Docket Operations, telephone 202–366–9826. SUPPLEMENTARY INFORMATION: The notice of public meeting; request for comments published in the Federal Register on October 11, 2012 (77 FR 61771) contains an inaccurate Internet link on page 61771. This correction provides the accurate Internet link to RSVP for the public meeting. ACTION: The National Offshore Safety Advisory Committee (NOSAC) will meet on November 7 and 8, 2012, in Houston, TX to discuss various issues related to SUMMARY: PO 00000 Frm 00064 Fmt 4703 Sfmt 4703 63849 safety of operations and other matters affecting the oil and gas offshore industry. These meetings are open to the public. DATES: NOSAC will meet Wednesday, November 7, 2012, from 1 p.m. to 5 p.m. and Thursday, November 8, 2012, from 8:30 a.m. to 5 p.m. Two subcommittees will meet the afternoon of November 7. Please note that the meetings may close early if the committee has completed its business or be extended based on the level of public comments. ADDRESSES: The meetings will be held at the Marriott South Hobby Airport Hotel, 9100 Gulf Freeway, Houston, TX 77017, https://www.marriott.com/houhh. The November 7 afternoon subcommittee meetings will be held in the Corpus Christi room. The November 8 meeting will also be held at Marriott South Hobby Airport Hotel, in the Corpus Christi/South Padre Rooms. For information on facilities or services for individuals with disabilities or to request special assistance at the meeting, contact the person listed in FOR FURTHER INFORMATION CONTACT as soon as possible. To facilitate public participation, we are inviting public comment on the issues to be considered by the committee as listed in the ‘‘AGENDA’’ section below. Comments must be submitted in writing no later than October 25, 2012, and must be identified by USCG–2012–0855 and may be submitted by one of the following methods: • Federal eRulemaking Portal: https:// www.regulations.gov. Follow the instructions for submitting comments. • Fax: (202) 493–2251. • Mail: Docket Management Facility (M–30), U.S. Department of Transportation, West Building Ground Floor, Room W12–140, 1200 New Jersey Avenue SE., Washington, DC 20590– 0001. • Hand Delivery: Same as mail address above, between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. The telephone number is 202–366–9329. • To avoid duplication, please use only one of these methods. Instructions: All submissions received must include the words ‘‘Department of Homeland Security’’ and the docket number for this action. Comments received will be posted without alteration at https://www.regulations.gov, including any personal information provided. You may review a Privacy Act notice regarding our public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316). Docket: For access to the docket to read documents or comments related to E:\FR\FM\17OCN1.SGM 17OCN1

Agencies

[Federal Register Volume 77, Number 201 (Wednesday, October 17, 2012)]
[Notices]
[Pages 63848-63849]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2012-25472]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Report on Carcinogens Evaluation of Pentachlorophenol; Request 
for Nominations of Scientific Experts

SUMMARY: The National Toxicology Program (NTP), Division of the 
National Toxicology Program (DNTP), National Institute of Environmental 
Health Sciences (NIEHS), is initiating development of the Report on 
Carcinogens (RoC) monograph on pentachlorophenol. To inform development 
of that monograph, the Office of the RoC (ORoC) will hold a web-based 
meeting to obtain information related to evaluating human epidemiologic 
studies on exposure to pentachlorophenol and cancer risk and invites 
the nomination of speakers. Nominees should have expertise in cancer 
epidemiology and knowledge of studies related to exposure to 
pentachlorophenol. Self-nomination is permitted.

DATES: The deadline for nominations is December 3, 2012.

ADDRESSES: Nominations should be submitted to Dr. Ruth Lunn, Director, 
ORoC, DNTP, NIEHS, P.O. Box 12233, MD K2-14, Research Triangle Park, NC 
27709; telephone (919) 316-4637; FAX: (301) 480-2970; 
lunn@niehs.nih.gov. Courier address: NIEHS, Room 2138, 530 Davis Drive, 
Morrisville, NC 27560.

FOR FURTHER INFORMATION CONTACT: Dr. Ruth Lunn, Director, ORoC, DNTP, 
NIEHS, P.O. Box 12233, MD K2-14, Research Triangle Park, NC 27709; 
telephone (919) 316-4637; FAX: (301) 480-2970; lunn@niehs.nih.gov. 
Courier address: NIEHS, Room 2138, 530 Davis Drive, Morrisville, NC 
27560.

SUPPLEMENTARY INFORMATION: Background: Pentachlorophenol (including its 
sodium salts) is a chlorinated aromatic compound that is used primarily 
as a wood preservative in the United States. It was selected for 
evaluation for the RoC based on widespread past use and current 
exposure in the United States and an adequate database of cancer 
studies.
    The final concept document for pentachlorophenol, which outlines 
the rationale for its selection for RoC evaluation and the proposed 
approach for development of the cancer evaluation component of the RoC 
monograph on pentachlorophenol, is available on the RoC Web site ( 
https://ntp.niehs.nih.gov/go/37897). The NTP Board of Scientific 
Counselors provided comments on the draft concept at its meeting on 
June 21, 2012 (minutes available at https://ntp.niehs.nih.gov/go/9741).
    Important to the evaluation of the potential carcinogenicity of 
pentachlorophenol is the assessment of evidence from human cancer 
studies. From an initial search of the peer-reviewed literature, the 
available human epidemiologic studies include: (1) Several case-control 
studies (primarily of hematopoietic cancer) reporting risk estimates 
for job titles associated with pentachlorophenol exposure or exposure 
to chlorophenols with limited information on exposure specific for 
pentachlorophenol, (2) case-control studies reporting risk estimates 
specific for pentachlorophenol, and (3) cohort studies of 
pentachlorophenol production workers or users. A key issue in 
evaluating the evidence in humans is the potential for confounding from 
co-exposures, especially contaminants of pentachlorophenol formed 
during its production. Major cancers of interest are multiple myeloma, 
lymphoma, and soft-tissue sarcoma.
    Meeting Information: ORoC will hold a web-based meeting to obtain 
information related to evaluating human epidemiologic studies on 
exposure to pentachlorophenol and cancer risk, especially for lymphoma 
and multiple myeloma. In planning for this event, ORoC is inviting the 
nomination of speakers who would make presentations that focus on the 
methods used in human epidemiologic studies of pentachlorophenol to 
evaluate potential confounding from occupational co-exposures, other 
types of information that may be important in evaluating potential 
confounding, and how exposure to confounders may affect each study's 
findings. Once plans for the web-based meeting are finalized, 
additional information including agenda, speakers, logistics, and 
registration, will be announced in a subsequent Federal Register 
notice.
    Request for Nominations of Speakers: ORoC invites the nomination of 
speakers for the web-based meeting with expertise in epidemiology and 
knowledge of cancer studies on exposure to pentachlorophenol. Self-
nomination is permitted. Each nomination should include (1) Contact 
information for the nominee [name,

[[Page 63849]]

affiliation (if any), address, telephone, fax, and email], (2) a short 
description of the individual's expertise relative to the review of 
human epidemiologic studies of exposure to pentachlorophenol and cancer 
risk, (3) curriculum vitae, and (4) an abstract describing what would 
be covered in the talk to address the presentations' focus as noted 
above in ``Meeting Information.'' Persons submitting nominations should 
provide their name, contact information, affiliation, and sponsoring 
organization (if any). Nominations should be submitted to Dr. Lunn (see 
ADDRESSES); their receipt will be acknowledged by email. The deadline 
for nominations is December 3, 2012. Persons selected as speakers will 
be notified by email at least 30 days prior to the meeting.
    Background Information on the RoC: The RoC is a congressionally 
mandated document that identifies and discusses substances that may 
pose a hazard to human health by virtue of their carcinogenicity. 
Substances are listed in the report as either known or reasonably 
anticipated human carcinogens. The NTP prepares the RoC on behalf of 
the Secretary of Health and Human Services following a formal, multi-
step process for review and evaluation of selected substances (https://ntp.niehs.nih.gov/go/rocprocess). Information about the RoC is 
available on the RoC Web site (https://ntp.niehs.nih.gov/go/roc) or by 
contacting Dr. Lunn (see ADDRESSES).

    Dated: October 11, 2012.
John R. Bucher,
Associate Director, National Toxicology Program.
[FR Doc. 2012-25472 Filed 10-16-12; 8:45 am]
BILLING CODE 4140-01-P
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