National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings, 56660-56661 [2012-22480]

Download as PDF 56660 Federal Register / Vol. 77, No. 178 / Thursday, September 13, 2012 / Notices (e.g., osteoporosis, cleidocranial dysplasia and intervertebral disk degeneration). Competitive Advantages: • Proof of concept demonstrated in a mouse model. • Compounds have been previously tested in clinical studies for anti-HIV drugs. Development Stage: • Early-stage. • Pre-clinical. • In vitro data available. • In vivo data available (animal). Inventors: Pu Paul Liu (NHGRI), Wei Zheng (NCATS), Juan J. Marugan (NCATS), Noel T. Southall (NCATS), Lea Cunningham (NCI). Publication: Cunningham L, et al. Identification of benzodiazepine Ro5– 3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1–CBFb interaction. Proc Natl Acad Sci USA. 2012 Sep 4;109(36):14592–7. [PMID 22912405]. Intellectual Property: HHS Reference No. E–060–2011/0— • U.S. Provisional Application No. 61/453,863 filed 17 Mar 2011 • PCT Application No. PCT/US2012/ 029169 filed 15 Mar 2012 Licensing Contact: Sabarni K. Chatterjee, Ph.D.; 301–435–5587; chatterjeesa@mail.nih.gov. Collaborative Research Opportunity: The National Human Genome Research Institute (NHGRI), Oncogenesis and Development Section, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize benzodiazepine compounds described above to treat CBF leukemia, AML, ALL, and/or other RUNX-related disorders. Please contact Claire T. Driscoll, Director of NHGRI Technology Transfer Office (cdriscoll@mail.nih.gov; 301–594–2235) for more information. mstockstill on DSK4VPTVN1PROD with NOTICES Novel Methods for Using Biomarkers To Monitor Glucose Levels and Screen for Diabetes Risk Description of Technology: A primary goal of diabetes therapy is to improve control of blood glucose levels (known as glycemic control) in patients. Prospective studies of both Type 1 and Type 2 diabetes indicate that careful glycemic control significantly reduces the risk of microvascular, neurological, and cardiovascular complications of diabetes. The current method of monitoring glycemic control involves measuring levels of the intracellular hemoglobin (HbA1C). However, levels of HbA1C reflect glycemic control over a timeframe of several months and are VerDate Mar<15>2010 19:13 Sep 12, 2012 Jkt 226001 susceptible to a variety of perturbing factors such as hematologic disorders, kidney disease, aspirin or penicillin use, or alcohol intake. This technology describes a family of novel glycated peptide and protein biomarkers for glycemic control, as well as a method to monitor glycemic control in diabetic patients. In contrast to intracellular HbA1C, this technology detects glycated plasma proteins, which may reflect changes in glycemic control more rapidly and with more sensitivity. A diagnostic test developed using this technology could be envisioned to supplement or replace current HbA1Cbased glycemic monitoring and screen individuals for risk of diabetes. Potential Commercial Applications: • Diagnostic test to measure glycemic control in diabetic patients • Diagnostic test to screen patients for risk of developing diabetes Competitive Advantages: • Detects plasma proteins rather than intracellular markers • May provide more rapid and sensitive detection than currently used methods Development Stage: • Early-stage • In vitro data available Inventor: Perry J. Blackshear (NIEHS). Intellectual Property: HHS Reference No. E–057–2005/0— • PCT Application No. PCT/US2007/ 063385 filed 06 Mar 2007 • U.S. Application No. 12/281,909 filed 27 Oct 2008 Licensing Contact: Tara Kirby, Ph.D.; 301–435–4426; tarak@mail.nih.gov. A Novel Glucocorticoid Receptor Cofactor for Use as an Adjunct to Steroid-Based Therapies Description of Technology: Methods of using STAMP (SRC–1 and TIF–2 Associated Modulatory Protein) polypeptides for modulating steroid or nuclear receptor activity, alone or in combination with a steroid or nuclear receptor modulator. The novel protein, STAMP, modulates the trans-activation properties of glucocorticoid receptors and other steroid receptors. STAMP may be useful as a steroid-sparing agent for decreasing the severity of unwanted side-effects during steroid treatment, particularly in long-term treatment for chronic disease. Steroid hormones such as androgens and glucocorticoids are used in the treatment of many diseases. They act to regulate many physiological responses by binding to steroid receptors. However, because steroid receptors are expressed in many tissues, efforts to therapeutically modify the effects of steroid hormones on a specific tissue or PO 00000 Frm 00055 Fmt 4703 Sfmt 4703 on a specific receptor of the steroid receptor family often cause undesirable effects in other tissues or on other receptors. Potential Commercial Applications: Adjunct to steroid-based therapies for diseases such as arthritis, asthma, inflammatory and autoimmune diseases. Competitive Advantages: • Reduce the severity of unwanted side-effects from conventional steroid hormone therapies. • Particularly beneficial for long-term therapies. Development Stage: • Early-stage • In vitro data available Inventors: S. Stoney Simons and Yuanzheng He (NIDDK). Publications: 1. He Y, et al. STAMP alters the growth of transformed and ovarian cancer cells. BMC Cancer. 2010 Apr 7;10:128. [PMID 20374646] 2. He Y, Simons SS Jr. STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression. [PMID 17116691] 3. He Y, et al. Modulation of induction properties of glucocorticoid receptoragonist and -antagonist complexes by coactivators involves binding to receptors but is independent of ability of coactivators to augment transactivation. [PMID 12376547] Intellectual Property: HHS Reference No. E–056–2004/0—U.S. Patent No. 7,867,500 issued 11 Jan 2011. Licensing Contact: Tara Kirby, Ph.D.; 301–435–4426; tarak@mail.nih.gov. Dated: September 7, 2012. Richard U. Rodriguez, Director, Division of Technology Development and Transfer, Office of Technology Transfer, National Institutes of Health. [FR Doc. 2012–22497 Filed 9–12–12; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial E:\FR\FM\13SEN1.SGM 13SEN1 Federal Register / Vol. 77, No. 178 / Thursday, September 13, 2012 / Notices property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Microbiology, Infectious Diseases and AIDS Initial Review Group; Microbiology and Infectious Diseases B Subcommittee. MID–B October 2012. Date: October 9, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Courtyard by Marriott, 5520 Wisconsin Avenue, Chevy Chase, MD 20815. Contact Person: Nancy Lewis Ernst, Ph.D., Scientific Review Officer, Scientific Review Program, Division of Extramural Activities, National Institutes of Health/NIAID, 6700B Rockledge Drive, MSC 7616, Bethesda, MD 20892–7616, 301–451–7383, nancy.ernst@nih.gov. Name of Committee: Microbiology, Infectious Diseases and AIDS Initial Review Group; Microbiology and Infectious Diseases Research Committee. Date: October 11, 2012. Time: 10 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Rockledge 6700, 6700B Rockledge Drive, Bethesda, MD 20817, (Telephone Conference Call). Contact Person: Michelle M. Timmerman, Ph.D., Scientific Review Officer, Scientific Review Program, DEA/NIAID/NIH/DHHS, Room 2217, 6700B Rockledge Drive, MSC– 7616, Bethesda, MD 20892–7616, 301–451– 4573, timmermanm@niaid.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.855, Allergy, Immunology, and Transplantation Research; 93.856, Microbiology and Infectious Diseases Research, National Institutes of Health, HHS) Dated: September 7, 2012. David Clary, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2012–22480 Filed 9–12–12; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health mstockstill on DSK4VPTVN1PROD with NOTICES Center for Scientific Review; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose VerDate Mar<15>2010 19:13 Sep 12, 2012 Jkt 226001 confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; PAR–11– 259: Pregnancy in Women with Disabilities. Date: October 2, 2012. Time: 11 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20817, (Telephone Conference Call). Contact Person: Priscah Mujuru, RN, MPH, DRPH, COHNS, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 3139, MSC 7770, Bethesda, MD 20892, 301–594–6594, mujurup@mail.nih.gov. Name of Committee: Immunology Integrated Review Group; Innate Immunity and Inflammation Study Section. Date: October 4–5, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Aloft Washington National Harbor, 156 Waterfront Street, Oxon Hill, MD. Contact Person: Tina McIntyre, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4202, MSC 7812, Bethesda, MD 20892, 301–594– 6375, mcintyrt@csr.nih.gov. Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Neurodevelopment, Plasticity, and Regeneration. Date: October 9, 2012. Time: 1 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Carol Hamelink, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4192, MSC 7850, Bethesda, MD 20892, (301) 213– 9887, hamelinc@csr.nih.gov. Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Muscle and Bone, Function, Metabolism and Regeneration. Date: October 9, 2012. Time: 1:30 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Rajiv Kumar, Ph.D., Chief, MOSS IRG, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4216, MSC 7802, Bethesda, MD 20892, 301–435–1212, kumarra@csr.nih.gov. Name of Committee: Cell Biology Integrated Review Group; Development—2 Study Section. PO 00000 Frm 00056 Fmt 4703 Sfmt 4703 56661 Date: October 11, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Renaissance Washington DC, Dupont Circle, 1143 New Hampshire Avenue NW., Washington, DC 20037. Contact Person: Rass M Shayiq, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 2182, MSC 7818, Bethesda, MD 20892, (301) 435– 2359, shayiqr@csr.nih.gov. Name of Committee: Cell Biology Integrated Review Group; Cellular Signaling and Regulatory Systems Study Section. Date: October 11, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: The Allerton Hotel, 701 North Michigan Avenue, Chicago, IL 60611. Contact Person: Elena Smirnova, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5187, MSC 7840, Bethesda, MD 20892, 301–357– 9112, smirnove@csr.nih.gov. Name of Committee: Genes, Genomes, and Genetics Integrated Review Group; Therapeutic Approaches to Genetic Diseases Study Section. Date: October 11, 2012. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892, (Virtual Meeting). Contact Person: Michael K Schmidt, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 2214, MSC 7890, Bethesda, MD 20892, (301) 435– 1147, mschmidt@mail.nih.gov. Name of Committee: Surgical Sciences, Biomedical Imaging and Bioengineering Integrated Review Group; Bioengineering, Technology and Surgical Sciences Study Section. Date: October 11–12, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Sheraton Delfina Santa Monica, 530 Pico Boulevard, Santa Monica, CA 90405. Contact Person: Khalid Masood, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5120, MSC 7854, Bethesda, MD 20892, 301–435– 2392, masoodk@csr.nih.gov. Name of Committee: Cell Biology Integrated Review Group; Biology of the Visual System Study Section. Date: October 11–12, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Residence Inn Bethesda, 7335 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Michael H Chaitin, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5202, E:\FR\FM\13SEN1.SGM 13SEN1

Agencies

[Federal Register Volume 77, Number 178 (Thursday, September 13, 2012)]
[Notices]
[Pages 56660-56661]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2012-22480]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Institute of Allergy and Infectious Diseases; Notice of 
Closed Meetings

    Pursuant to section 10(d) of the Federal Advisory Committee Act, as 
amended (5 U.S.C. App.), notice is hereby given of the following 
meetings.
    The meetings will be closed to the public in accordance with the 
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 
U.S.C., as amended. The grant applications and the discussions could 
disclose confidential trade secrets or commercial

[[Page 56661]]

property such as patentable material, and personal information 
concerning individuals associated with the grant applications, the 
disclosure of which would constitute a clearly unwarranted invasion of 
personal privacy.

    Name of Committee: Microbiology, Infectious Diseases and AIDS 
Initial Review Group; Microbiology and Infectious Diseases B 
Subcommittee. MID-B October 2012.
    Date: October 9, 2012.
    Time: 8 a.m. to 5 p.m.
    Agenda: To review and evaluate grant applications.
    Place: Courtyard by Marriott, 5520 Wisconsin Avenue, Chevy 
Chase, MD 20815.
    Contact Person: Nancy Lewis Ernst, Ph.D., Scientific Review 
Officer, Scientific Review Program, Division of Extramural 
Activities, National Institutes of Health/NIAID, 6700B Rockledge 
Drive, MSC 7616, Bethesda, MD 20892-7616, 301-451-7383, 
nancy.ernst@nih.gov.

    Name of Committee: Microbiology, Infectious Diseases and AIDS 
Initial Review Group; Microbiology and Infectious Diseases Research 
Committee.
    Date: October 11, 2012.
    Time: 10 a.m. to 5 p.m.
    Agenda: To review and evaluate grant applications.
    Place: National Institutes of Health, Rockledge 6700, 6700B 
Rockledge Drive, Bethesda, MD 20817, (Telephone Conference Call).
    Contact Person: Michelle M. Timmerman, Ph.D., Scientific Review 
Officer, Scientific Review Program, DEA/NIAID/NIH/DHHS, Room 2217, 
6700B Rockledge Drive, MSC-7616, Bethesda, MD 20892-7616, 301-451-
4573, timmermanm@niaid.nih.gov.

(Catalogue of Federal Domestic Assistance Program Nos. 93.855, 
Allergy, Immunology, and Transplantation Research; 93.856, 
Microbiology and Infectious Diseases Research, National Institutes 
of Health, HHS)

    Dated: September 7, 2012.
David Clary,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2012-22480 Filed 9-12-12; 8:45 am]
BILLING CODE 4140-01-P
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