Statement of Cooperation Between the Food and Drug Administration and the Secretaria of Health of the United Mexican States: Safety and Sanitary Quality of Fresh and Frozen Molluscan Shellfish Exported From Mexico to the United States, 41418-41428 [2012-17081]
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41418
Federal Register / Vol. 77, No. 135 / Friday, July 13, 2012 / Notices
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the widest possible opportunity to
obtain public comment, FDA is
soliciting either electronic or written
comments on all aspects of the public
meeting topics. The deadline for
submitting comments related to this
public meeting is October 12, 2012
(2 weeks after the public meeting).
Regardless of attendance at the public
meeting, interested persons may submit
either electronic or written comments.
Submit electronic comments to https://
www.regulations.gov. Submit written
comments to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, rm.
1061, Rockville, MD 20852. It is only
necessary to send one set of comments.
Please identify comments with the
docket number found in brackets in the
heading of this document. In addition,
when responding to specific topics as
outlined in section III of this document,
please identify the topic you are
addressing. Received comments may be
seen in the Division of Dockets
Management between 9 a.m. and 4 p.m.,
Monday through Friday, and will be
posted at https://www.regulations.gov.
Transcripts: Please be advised that as
soon as a transcript is available, it will
be accessible at https://
www.regulations.gov. It may be viewed
at the Division of Dockets Management
(see Comments). A transcript will also
be available in either hardcopy or on
CD–ROM, after submission of a
Freedom of Information request. Written
requests are to be sent to the Division
of Freedom of Information (ELEM–
1029), Food and Drug Administration,
12420 Parklawn Dr., Element Bldg.,
Rockville, MD 20857. A link to the
transcript will also be available
approximately 45 days after the public
meeting on the Internet at https://
www.fda.gov/MedicalDevices/
NewsEvents/WorkshopsConferences/
default.htm. (Select this meeting from
the posted events list.)
SUPPLEMENTARY INFORMATION:
I. Background
In the event of an accident or terrorist
attack that exposes a large population to
radiation, an accurate assessment of the
absorbed ionizing radiation dose
received by victims will be essential for
triage and medical management.
Because there is currently no cleared or
approved radiation biodosimeter for use
in a mass exposure scenario, the
development of proper radiation
biodosimetry tools is a critical unmet
public health need. However, because it
is impossible to obtain samples that
accurately reflect the intended use
population of the device, validating the
performance of radiation biodosimeters
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poses significant scientific and
regulatory challenges. As such, FDA is
holding this public meeting to obtain
input from academia, Government,
industry, and other stakeholders on the
clinical application and scientific and
technological challenges for
performance validation of radiation
biodosimetry devices. Individual
perspectives from meeting participants
may help to identify solutions for the
scientific challenges associated with
radiation biodosimetry development,
and may clarify the regulatory path
forward to ensure device safety and
effectiveness and thereby provide
significant clinical and public health
benefits.
II. Meeting Overview
The public meeting will consist of the
following: (1) Presentations providing
background on anticipated uses of
radiation biodosimetry medical
countermeasure devices, (2) the device
design and performance evaluation
challenges identified by FDA, (3)
specific technology considerations in
radiation biodosimetry, (4) an open
public comment session, and (5) an
open discussion on topics identified by
FDA and those raised by the
presentations (see section III of this
document). The purpose of this meeting
is for participants to share individual
perspectives during the discussions.
FDA is not seeking group opinions,
recommendations, or advice on any
matter. Additional information,
including a meeting agenda, will be
available on the Internet immediately
after publication of this document in the
Federal Register. This information will
be placed on file in the public docket
(docket number found in brackets in the
heading of this document), which is
available at https://www.regulations.gov.
This information will also be available
at https://www.fda.gov/MedicalDevices/
NewsEvents/WorkshopsConferences/
default.htm. (Select the appropriate
meeting from the list.)
III. Topics for Discussion at the Public
Meeting
The following questions represent the
kinds of topics that will be discussed at
the meeting.
1. Performance Evaluation for
Radiation Biodosimetry:
A. What data would support the use
of ex vivo radiation human samples in
device performance validation?
B. What types of in vivo radiation
human samples may be available to
validate the performance of radiation
biodosimeters?
C. What pre-clinical or clinical animal
model testing might be necessary to
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demonstrate radiation biodosimeter
performance?
D. Would a non-human primate
pivotal clinical study be appropriate to
support clearance/approval of
biodosimetry MCM devices?
E. What data would support device
applicability to both partial body and
total body irradiation scenarios?
F. How should the impact of delays in
sampling, delays in testing, combined
injury, and other potential confounders
on the performance of a radiation
biodosimeter be assessed?
G. What challenges does the use of
novel technologies bring to radiation
biodosimetry development and
performance validation?
2. Public Health Considerations for
Radiation Biodosimetry:
A. What device design elements
would address the need for rapid
patient triage in a crisis scenario?
B. What device design elements
should be included to account for the
potential for high demand, device use
by untrained medical personnel, and
therapeutic decisionmaking based on
limited resources?
C. What information should the
Agency clarify in regards to the
regulatory path forward for radiation
biodosimetry MCM devices?
Dated: July 5, 2012.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2012–17082 Filed 7–12–12; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2012–N–0004]
Statement of Cooperation Between the
Food and Drug Administration and the
Secretaria of Health of the United
Mexican States: Safety and Sanitary
Quality of Fresh and Frozen Molluscan
Shellfish Exported From Mexico to the
United States
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is providing
notice of a Statement of Cooperation
(SOC) between FDA and Secretariat of
Health (SS) of the United Mexican
States, through the Federal Commission
for Protection from Sanitary Risks
(COFEPRIS). The purpose of the SOC is
to safeguard public health and to ensure
the safety and sanitary quality of fresh
SUMMARY:
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Office, Office of International Programs,
Food and Drug Administration, 10903
New Hampshire Ave., Bldg. 31, Rm.
3550, Silver Spring, MD 20993–0002,
301–796–8400, Fax: 301–595–7941.
In
accordance with 21 CFR 20.108(c),
which states that all written agreements
SUPPLEMENTARY INFORMATION:
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and MOUs between FDA and others
shall be published in the Federal
Register, the Agency is publishing
notice of this MOU.
Dated: July 5, 2012.
Leslie Kux,
Assistant Commissioner for Policy.
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srobinson on DSK4SPTVN1PROD with NOTICES
and frozen molluscan shellfish
harvested from aquacultured and wild
populations that are now or may be
exported into the United States.
DATES: The arrangement came into effect
on June 28, 2012 for 5 years.
FOR FURTHER INFORMATION CONTACT:
Phyllis Marquitz, Latin American
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[FR Doc. 2012–17081 Filed 7–12–12; 8:45 am]
BILLING CODE 4160–01–C
DEPARTMENT OF HEALTH AND
HUMAN SERVICE
Indian Health Services
[HHS–2012–IHS–HLY–0001]
Healthy Lifestyles in Youth Project;
Proposed Single Source Cooperative
Agreement With National Congress of
American Indians
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Application Due Date: August 16,
2012.
Review Date: August 21, 2012.
Earliest Start Date: September 1, 2012.
I. Funding Opportunity Description
The Indian Health Service (IHS)
proposes a single source competing
continuation cooperative agreement
with the National Congress of American
Indians (NCAI) for the purpose of
continued implementation of the
Healthy Lifestyles in Youth Project in
selected Native American Boys and
Girls Clubs of America. This program
promotes healthy lifestyles among
American Indian and Alaska Native (AI/
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AN) youth using the curriculum
‘‘Together Raising Awareness for Indian
Life’’ (TRAIL) among selected Boys and
Girls Club sites.
This program is authorized under the
authority of the Snyder Act, 25 U.S.C.
13; the Transfer Act, 42 U.S.C. 2001;
and the Public Health Service Act, as
amended, 42 U.S.C. 241(a). Under this
cooperative agreement, IHS proposes to
enter into a collaborative effort/
initiative with NCAI, because of their
unique experience partnering with the
IHS and Boys and Girls Clubs of
America in successfully establishing
this program, as well as, their overall
expertise and experience in addressing
and evaluating healthy lifestyle
techniques in AI/AN youth. This
program is described in the Catalog of
Federal Domestic Assistance (CFDA)
under 93.933.
The focus of the project continues to
be on addressing healthy lifestyle
development, emphasizing nutrition
and physical activity for AI/AN children
and youth 6 through 17 years of age.
The long term goal is to prevent or delay
the onset of obesity and related diseases
such as type 2 diabetes. NCAI will
continue partnering work with selected
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Tribal Boys and Girls Club sites to: (a)
Provide health and physical education
programs; (b) help youth achieve and
maintain healthy lifestyles through
participation in fitness programs; (c)
help youth to acquire a range of
physical skills; and (d) help youth
develop a sense of teamwork and
cooperation.
These early intervention strategies
provide evidence based opportunities to
reduce and/or halt the increasing trend
of obesity and diabetes among youth
and young adults. Clubs that develop a
health promotion program that includes
the TRAIL curriculum may help curtail
the effects of unhealthy eating behaviors
and lack of physical activity that can
lead to obesity, diabetes, and other
chronic diseases later in life. The
T.R.A.I.L. curriculum was developed to
provide information on good nutrition
and to promote physical activity among
youth participating in Tribal Boys and
Girls Clubs. T.R.A.I.L. is a three-month
(12 lessons) program that provides
youth with a comprehensive
understanding of healthy lifestyles in
order to prevent diabetes. Woven
throughout the program are self-esteem
and prevention activities. Participants
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Federal Register / Vol. 77, No. 135 / Friday, July 13, 2012 / Notices
Agencies
[Federal Register Volume 77, Number 135 (Friday, July 13, 2012)]
[Notices]
[Pages 41418-41428]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2012-17081]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2012-N-0004]
Statement of Cooperation Between the Food and Drug Administration
and the Secretaria of Health of the United Mexican States: Safety and
Sanitary Quality of Fresh and Frozen Molluscan Shellfish Exported From
Mexico to the United States
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is providing notice of
a Statement of Cooperation (SOC) between FDA and Secretariat of Health
(SS) of the United Mexican States, through the Federal Commission for
Protection from Sanitary Risks (COFEPRIS). The purpose of the SOC is to
safeguard public health and to ensure the safety and sanitary quality
of fresh
[[Page 41419]]
and frozen molluscan shellfish harvested from aquacultured and wild
populations that are now or may be exported into the United States.
DATES: The arrangement came into effect on June 28, 2012 for 5 years.
FOR FURTHER INFORMATION CONTACT: Phyllis Marquitz, Latin American
Office, Office of International Programs, Food and Drug Administration,
10903 New Hampshire Ave., Bldg. 31, Rm. 3550, Silver Spring, MD 20993-
0002, 301-796-8400, Fax: 301-595-7941.
SUPPLEMENTARY INFORMATION: In accordance with 21 CFR 20.108(c), which
states that all written agreements and MOUs between FDA and others
shall be published in the Federal Register, the Agency is publishing
notice of this MOU.
Dated: July 5, 2012.
Leslie Kux,
Assistant Commissioner for Policy.
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[FR Doc. 2012-17081 Filed 7-12-12; 8:45 am]
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