National Institute of General Medical Sciences; Notice of Meeting, 24724-24725 [2012-9880]
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24724
Federal Register / Vol. 77, No. 80 / Wednesday, April 25, 2012 / Notices
February 1, 2011, letter, the Agency
acknowledged AstraZeneca’s agreement
to permit FDA to withdraw approval of
IRESSA under § 314.150(d) and waive
its opportunity for a hearing.
Therefore, under section 505(e) of the
Federal Food, Drug, and Cosmetic Act
(FD&C Act) (21 U.S.C. 355(e)) and
§ 314.150(d), and under authority
delegated by the Commissioner to the
Director, Center for Drug Evaluation and
Research, approval of NDA 21–399, and
all amendments and supplements
thereto, is withdrawn (see DATES).
Distribution of this product in interstate
commerce without an approved
application is illegal and subject to
regulatory action (see sections 505(a)
and 301(d) of the FD&C Act (21 U.S.C.
355(a) and 331(d)).
Dated: April 5, 2012.
Janet Woodcock,
Director, Center for Drug Evaluation and
Research.
[FR Doc. 2012–9944 Filed 4–24–12; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2012–N–0376]
Sanofi-aventis, U.S., LLC; Withdrawal
of Approval of a New Drug Application
for OFORTA
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is withdrawing
approval of a new drug application
(NDA) for OFORTA (fludarabine
phosphate) Tablets held by sanofiaventis, U.S., LLC (sanofi-aventis), 55
Corporate Dr., Bridgewater, NJ 08807–
0977. Sanofi-aventis has voluntarily
requested that approval of this
application be withdrawn, thereby
waiving its opportunity for a hearing.
DATES: Effective December 31, 2011.
FOR FURTHER INFORMATION CONTACT:
Martha Nguyen, Center for Drug
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 51, rm. 6250,
Silver Spring, MD 20993–0002, 301–
796–3601.
SUPPLEMENTARY INFORMATION: FDA
approved OFORTA (fludarabine
phosphate) Tablets on December 18,
2008, under the Agency’s accelerated
approval regulations, 21 CFR part 314,
subpart H. OFORTA is approved for use
as a single agent for the treatment of
pmangrum on DSK3VPTVN1PROD with NOTICES
SUMMARY:
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adult patients with B-cell chronic
lymphocytic leukemia whose disease
has not responded to or has progressed
during or after treatment with at least
one standard alkylating agentcontaining regimen. On February 10,
2011, FDA requested that sanofi-aventis
voluntarily withdraw OFORTA
(fludarabine phosphate) Tablets from
the market, because the postmarketing
study required as a condition of
approval under subpart H had not been
completed and clinical benefit had not
been verified. In a letter dated June 24,
2011, sanofi-aventis requested that FDA
withdraw approval of NDA 22–273 for
OFORTA (fludarabine phosphate)
Tablets under § 314.150(d), noting the
lack of commercial demand for
OFORTA and significant challenges to
completing the postmarketing study. In
that letter, sanofi-aventis also waived its
opportunity for a hearing, otherwise
provided under §§ 314.150 and 314.530.
In a letter dated July 8, 2011, the Agency
acknowledged sanofi-aventis’ agreement
to permit FDA to withdraw approval of
OFORTA under § 314.150(d) and waive
its opportunity for a hearing. The
Agency noted that the required
postmarketing study had not been
completed and clinical benefit had not
been verified.
Therefore, under section 505(e) of the
Federal Food, Drug, and Cosmetic Act
(FD&C Act) (21 U.S.C. 355(e)) and
§ 314.150(d), and under authority
delegated by the Commissioner to the
Director, Center for Drug Evaluation and
Research, approval of NDA 22–273, and
all amendments and supplements
thereto, is withdrawn (see DATES).
Distribution of this product in interstate
commerce without an approved
application is illegal and subject to
regulatory action (see sections 505(a)
and 301(d) of the FD&C Act (21 U.S.C.
355(a) and 331(d)).
Dated: April 5, 2012.
Janet Woodcock,
Director, Center for Drug Evaluation and
Research.
[FR Doc. 2012–9943 Filed 4–24–12; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of General Medical
Sciences; Notice of Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of a meeting of the
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National Advisory General Medical
Sciences Council.
The meeting will be open to the
public as indicated below, with
attendance limited to space available.
Individuals who plan to attend and
need special assistance, such as sign
language interpretation or other
reasonable accommodations, should
notify the Contact Person listed below
in advance of the meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Advisory
General Medical Sciences Council.
Date: May 24–25, 2012.
Closed: May 24, 2012, 8:30 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Natcher Building, Conference Rooms E1 &
E2, 45 Center Drive, Bethesda, MD 20892.
Open: May 25, 2012, 8:30 a.m. to
Adjournment.
Agenda: For the discussion of program
policies and issues, opening remarks, report
of the Director, NIGMS, and other business
of the Council.
Place: National Institutes of Health,
Natcher Building, Conference Rooms E1 &
E2, 45 Center Drive, Bethesda, MD 20892.
Contact Person: Ann A. Hagan, Ph.D.,
Associate Director for Extramural Activities,
NIGMS, NIH, DHHS, 45 Center Drive, Room
2AN24H, MSC 6200, Bethesda, MD 20892,
(301) 594–4499, hagana@nigms.nih.gov.
Any interested person may file written
comments with the committee by forwarding
the statement to the Contact Person listed on
this notice. The statement should include the
name, address, telephone number and when
applicable, the business or professional
affiliation of the interested person.
In the interest of security, NIH has
instituted stringent procedures for entrance
onto the NIH campus. All visitor vehicles,
including taxis, hotel, and airport shuttles
will be inspected before being allowed on
campus. Visitors will be asked to show one
form of identification (for example, a
government-issued photo ID, driver’s license,
or passport) and to state the purpose of their
visit. Information is also available on the
Institute’s/Center’s home page: https://
www.nigms.nih.gov/About/Council/ where
an agenda and any additional information for
the meeting will be posted when available.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.375, Minority Biomedical
Research Support; 93.821, Cell Biology and
Biophysics Research; 93.859, Pharmacology,
Physiology, and Biological Chemistry
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25APN1
Federal Register / Vol. 77, No. 80 / Wednesday, April 25, 2012 / Notices
Research; 93.862, Genetics and
Developmental Biology Research; 93.88,
Minority Access to Research Careers; 93.96,
Special Minority Initiatives, National
Institutes of Health, HHS)
Dated: April 17, 2012.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 2012–9880 Filed 4–24–12; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Fogarty International Center; Notice of
Meetings
pmangrum on DSK3VPTVN1PROD with NOTICES
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of a meeting of the Fogarty
International Center Advisory Board.
The meeting will be open to the
public as indicated below, with
attendance limited to space available.
Individuals who plan to attend and
need special assistance, such as sign
language interpretation or other
reasonable accommodations, should
notify the Contact Person listed below
in advance of the meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications
and/or contract Proposals and the
discussions could disclose confidential
trade secrets or commercial property
such as patentable materials, and
personal information concerning
individuals associated with the grant
applications and/or contract proposals,
the disclosure of which would
constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Fogarty International
Center Advisory Board.
Date: May 14–15, 2012.
Closed: May 14, 2012, 2 p.m. to 5 p.m.
Agenda: To review and evaluate grant
applications and/or proposals.
Place: National Institutes of Health,
Building 31, 31 Center Drive, C Wing, Room
B2C03, Bethesda, MD 20892.
Open: May 15, 2012, 9 a.m. to 3 p.m.
Agenda: Discussions will include the
renewal of the five-year strategic plan and
new priorities including emerging
technologies such as distance learning and
mHealth.
Place: National Institutes of Health,
Lawton L. Chiles International House,
Bethesda, MD 20892.
Contact Person: Robert Eiss, Public Health
Advisor, Fogarty International Center,
National Institutes of Health, 31 Center Drive,
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Room B2c02, Bethesda, MD 20892, (301)
496–1415, EISSR@MAIL.NIH.GOV.
Any interested person may file written
comments with the committee by forwarding
the statement to the Contact Person listed on
this notice. The statement should include the
name, address, telephone number and when
applicable, the business or professional
affiliation of the interested person.
In the interest of security, NIH has
instituted stringent procedures for entrance
onto the NIH campus. All visitor vehicles,
including taxicabs, hotel, and airport shuttles
will be inspected before being allowed on
campus. Visitors will be asked to show one
form of identification (for example, a
government-issued photo ID, driver’s license,
or passport) and to state the purpose of their
visit.
Information is also available on the
Institute’s/Center’s home page: www.nih.gov/
fic/about/advisory.html, where an agenda
and any additional information for the
meeting will be posted when available.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.106, Minority International
Research Training Grant in the Biomedical
and Behavioral Sciences; 93.154, Special
International Postdoctoral Research Program
in Acquired Immunodeficiency Syndrome;
93.168, International Cooperative
Biodiversity Groups Program; 93.934, Fogarty
International Research Collaboration Award;
93.989, Senior International Fellowship
Awards Program, National Institutes of
Health HHS)
Dated:
April 16, 2012.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
24725
Delivery Methodologies Member
Applications.
Date: May 7, 2012.
Time: 12 p.m. to 2 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892,
(Telephone Conference Call).
Contact Person: Jacinta Bronte-Tinkew,
Ph.D., Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 3164,
MSC 7770, Bethesda, MD 20892, (301) 806–
0009, brontetinkewjm@csr.nih.gov.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; Member
Conflict: Drugs, Alcohol and Learning.
Date: May 16–17, 2012.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892,
(Virtual Meeting).
Contact Person: Michael Selmanoff, PhD.,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 3134,
MSC 7844, Bethesda, MD 20892, 301–435–
1119, mselmanoff@csr.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.306, Comparative Medicine;
93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393–93.396, 93.837–93.844,
93.846–93.878, 93.892, 93.893, National
Institutes of Health, HHS)
Dated: April 16, 2012.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 2012–9882 Filed 4–24–12; 8:45 am]
[FR Doc. 2012–9914 Filed 4–24–12; 8:45 am]
BILLING CODE 4140–01–P
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institutes of Health
Center for Scientific Review; Notice of
Closed Meetings
National Institute of Neurological
Disorders and Stroke; Notice of
Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; Healthcare
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Fmt 4703
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Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the National Advisory
Neurological Disorders and Stroke
Council.
The meeting will be open to the
public as indicated below, with
attendance limited to space available.
Individuals who plan to attend and
need special assistance, such as sign
language interpretation or other
reasonable accommodations, should
notify the Contact Person listed below
in advance of the meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
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Agencies
[Federal Register Volume 77, Number 80 (Wednesday, April 25, 2012)]
[Notices]
[Pages 24724-24725]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2012-9880]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institute of General Medical Sciences; Notice of Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is hereby given of a meeting of the
National Advisory General Medical Sciences Council.
The meeting will be open to the public as indicated below, with
attendance limited to space available. Individuals who plan to attend
and need special assistance, such as sign language interpretation or
other reasonable accommodations, should notify the Contact Person
listed below in advance of the meeting.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications, the disclosure of which would
constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: National Advisory General Medical Sciences
Council.
Date: May 24-25, 2012.
Closed: May 24, 2012, 8:30 a.m. to 5 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, Natcher Building,
Conference Rooms E1 & E2, 45 Center Drive, Bethesda, MD 20892.
Open: May 25, 2012, 8:30 a.m. to Adjournment.
Agenda: For the discussion of program policies and issues,
opening remarks, report of the Director, NIGMS, and other business
of the Council.
Place: National Institutes of Health, Natcher Building,
Conference Rooms E1 & E2, 45 Center Drive, Bethesda, MD 20892.
Contact Person: Ann A. Hagan, Ph.D., Associate Director for
Extramural Activities, NIGMS, NIH, DHHS, 45 Center Drive, Room
2AN24H, MSC 6200, Bethesda, MD 20892, (301) 594-4499,
hagana@nigms.nih.gov.
Any interested person may file written comments with the committee
by forwarding the statement to the Contact Person listed on this
notice. The statement should include the name, address, telephone
number and when applicable, the business or professional affiliation
of the interested person.
In the interest of security, NIH has instituted stringent
procedures for entrance onto the NIH campus. All visitor vehicles,
including taxis, hotel, and airport shuttles will be inspected
before being allowed on campus. Visitors will be asked to show one
form of identification (for example, a government-issued photo ID,
driver's license, or passport) and to state the purpose of their
visit. Information is also available on the Institute's/Center's
home page: https://www.nigms.nih.gov/About/Council/ where an agenda
and any additional information for the meeting will be posted when
available.
(Catalogue of Federal Domestic Assistance Program Nos. 93.375,
Minority Biomedical Research Support; 93.821, Cell Biology and
Biophysics Research; 93.859, Pharmacology, Physiology, and
Biological Chemistry
[[Page 24725]]
Research; 93.862, Genetics and Developmental Biology Research;
93.88, Minority Access to Research Careers; 93.96, Special Minority
Initiatives, National Institutes of Health, HHS)
Dated: April 17, 2012.
Jennifer S. Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 2012-9880 Filed 4-24-12; 8:45 am]
BILLING CODE 4140-01-P