National Institute of Child Health and Human Development; New Proposed Collection; Comment Request Stress and Cortisol Measurement for the National Children's Study, 9666-9668 [2012-3809]
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Federal Register / Vol. 77, No. 33 / Friday, February 17, 2012 / Notices
necessary for the proper performance of
the function of the agency, including
whether the information will have
practical utility; (2) evaluate the
accuracy of the agency’s estimate of the
burden of the proposed collection of
information, including the validity of
the methodology and assumptions used;
(3) enhance the quality, utility, and
clarity of the information to be
collected; and (4) minimize the burden
of the collection of information on those
who are to respond, including the use
of appropriate automated, electronic,
mechanical, or other technological
collection techniques or other forms of
information technology.
Direct Comments to OMB: Written
comments and/or suggestions regarding
the item(s) contained in this notice,
especially regarding the estimated
public burden and associated response
time, should be directed to the
Attention: NIH Desk Officer, Office of
Management and Budget, at
OIRA_submission@omb.eop.gov or by
fax to 202–395–6974. To request more
information on the proposed project or
to obtain a copy of the data collection
plans and instruments, contact
Nathaniel Rothman, Senior Investigator
for the Occupational and Environmental
Epidemiology Branch, Division of
Epidemiology and Genetics, National
Cancer Institute, 6120 Executive
Boulevard, Room 8118, Rockville, MD
20892 or call non-toll-free number 301–
496–9093 or email your request,
including your address to:
rothmann @mail.nih.gov.
Comments Due Date: Comments
regarding this information collection are
best assured of having their full effect if
received within 15 days of the date of
this publication.
Dated: February 13, 2012.
Vivian Horovitch-Kelley,
NCI Project Clearance Liaison, National
Institutes of Health.
[FR Doc. 2012–3830 Filed 2–16–12; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
mstockstill on DSK4VPTVN1PROD with NOTICES
National Institutes of Health
National Institute of Child Health and
Human Development; New Proposed
Collection; Comment Request Stress
and Cortisol Measurement for the
National Children’s Study
Summary: In compliance with the
requirement of Section 3506(c)(2)(A) of
the Paperwork Reduction Act of 1995,
for opportunity for public comment on
proposed data collection projects, the
VerDate Mar<15>2010
19:08 Feb 16, 2012
Jkt 226001
National Institute of Child Health and
Human Development (NICHD), the
National Institutes of Health (NIH) will
publish periodic summaries of proposed
projects to be submitted to the Office of
Management and Budget (OMB) for
review and approval.
Proposed Collection
Title: Stress and Cortisol
Measurement Substudy for the National
Children’s Study (NCS). Type of
Information Collection Request: NEW.
Need and Use of Information Collection:
The Children’s Health Act of 2000 (Pub.
L. 106–310) states:
(a) PURPOSE.—It is the purpose of this
section to authorize the National Institute of
Child Health and Human Development to
conduct a national longitudinal study of
environmental influences (including
physical, chemical, biological, and
psychosocial) on children’s health and
development.
(b) IN GENERAL.—The Director of the
National Institute of Child Health and
Human Development shall establish a
consortium of representatives from
appropriate Federal agencies (including the
Centers for Disease Control and Prevention,
the Environmental Protection Agency) to—
(1) Plan, develop, and implement a
prospective cohort study, from birth to
adulthood, to evaluate the effects of both
chronic and intermittent exposures on child
health and human development; and
(2) Investigate basic mechanisms of
developmental disorders and environmental
factors, both risk and protective, that
influence health and developmental
processes.
(c) REQUIREMENT.—The study under
subsection (b) shall—
(1) Incorporate behavioral, emotional,
educational, and contextual consequences to
enable a complete assessment of the physical,
chemical, biological, and psychosocial
environmental influences on children’s wellbeing;
(2) Gather data on environmental
influences and outcomes on diverse
populations of children, which may include
the consideration of prenatal exposures; and
(3) Consider health disparities among
children, which may include the
consideration of prenatal exposures.
To fulfill the requirements of the
Children’s Health Act, the Stress and
Cortisol Measurement Substudy will
develop an optimized, item-reduced
measure of self-reported stress that is
supported empirically through
convergent validity analysis of stress
biomarkers. Specifically, key
moderators of stress biomarkers will be
evaluated to inform the efficiency and
quality of measurements during
pregnancy. Development of a
scientifically robust maternal stress
measure would measure chronic stress
more efficiently, would not require
biospecimen collection and biomarker
PO 00000
Frm 00047
Fmt 4703
Sfmt 4703
analyses, and would thereby reduce
participant burden and NCS Vanguard
(Pilot) and NCS Main Study costs. With
this information collection request, the
NCS seeks to obtain OMB’s clearance to
conduct a substudy aimed at developing
a validated questionnaire that will
reflect specific biological and
physiological measures of maternal
stress.
Background
The National Children’s Study is a
prospective, national longitudinal study
of the interaction between environment,
genetics on child health and
development. The Study defines
‘‘environment’’ broadly, taking a
number of natural and man-made
environmental, biological, genetic, and
psychosocial factors into account. By
studying children through their
different phases of growth and
development, researchers will be better
able to understand the role these factors
have on health and disease. Findings
from the Study will be made available
as the research progresses, making
potential benefits known to the public
as soon as possible. The National
Children’s Study is led by a consortium
of federal partners: the U.S. Department
of Health and Human Services (https://
www.hhs.gov/) (including the Eunice
Kennedy Shriver National Institute of
Child Health and Human Development
(https://www.nichd.nih.gov/) and the
National Institute of Environmental
Health Sciences (https://
www.niehs.nih.gov/) of the National
Institutes of Health (https://
www.nih.gov/) and the Centers for
Disease Control and Prevention (https://
www.cdc.gov/)), and the U.S.
Environmental Protection Agency
(https://www.epa.gov/).
To conduct the detailed preparation
needed for a study of this size and
complexity, the NCS was designed to
include a preliminary pilot study
known as the Vanguard Study. The
purpose of the Vanguard Study is to
assess the feasibility, acceptability, and
cost of the recruitment strategy, study
procedures, and outcome assessments
that are to be used in the NCS Main
Study. The Vanguard Study begins prior
to the NCS Main Study and will run in
parallel with the Main Study. At every
phase of the NCS, the multiple
methodological studies conducted
during the Vanguard phase will inform
the implementation and analysis plan
for the Main Study.
In this information collection request,
the NCS requests approval from OMB to
perform a multi-center substudy, called
the Stress and Cortisol Measurement
Substudy. This substudy aims to
E:\FR\FM\17FEN1.SGM
17FEN1
9667
Federal Register / Vol. 77, No. 33 / Friday, February 17, 2012 / Notices
determine the most reliable, acceptable,
and cost-efficient approach for assessing
maternal stress. Maternal stress is of
particular interest to the NCS due to
studies that have shown an association
between maternal stress and negative
health outcomes, including preterm
birth which is one of the most important
problems in maternal-child health in the
US. Stress factors are also more
prevalent in the population of sociodemographically disadvantaged women
who are at an increased risk for preterm
birth. Maternal stress is associated with
additional health outcomes, such as
still-birth, low birth weight, problems in
offspring brain function and behavior
(including lower IQ and impaired
executive function), immune-related
problems such as allergies and asthma,
congenital malformations, infections,
and numerous disorders of organ
systems.
Development of a scientifically robust
and validated questionnaire to reflect
specific physiological measures of stress
would allow us to measure chronic
stress more efficiently, would not
require biospecimen collection and
biomarker analyses, and would thereby
reduce participant burden and Study
costs. To develop this instrument, the
NCS will collect several types of
information from substudy participants
through medical record abstraction,
questionnaires (a series of validated
stress measures), physiological
measures (heart rate and self-reported
stress), and several types of
biospecimens.
Frequency of Response: Annual [As
needed].
Affected Public: Pregnant women and
their children.
Type of Respondents: Pregnant
women who are not geographically
eligible to enroll in the NCS Vanguard
Study.
Annual Reporting Burden: See Table
1. The annualized cost to respondents is
estimated at: $74,677 (based on $10 per
hour). There are no Capital Costs to
report. There are no Operating or
Maintenance Costs to report.
TABLE 1—ESTIMATED ANNUAL REPORTING BURDEN SUMMARY, STRESS AND CORTISOL MEASUREMENTS
Data collection activity
Screening ..........................................
Consent .............................................
Saliva Self-Collection Demonstration
Urine Self-Collection Instructions ......
Ecological Momentary Assessment
Training.
Visit 1 Stress Questionnaire .............
Adult Blood ........................................
Adult Urine ........................................
Adult Hair ..........................................
Adult Saliva .......................................
Demographic and Health Interview ..
Participant
Contact
Information
Sheet.
Take-Home Questionnaire ................
Time Diary .........................................
Heart Monitoring ...............................
Visit 2 Stress Questionnaire .............
Stressful Life
Checklist.
Events
Schedule
mstockstill on DSK4VPTVN1PROD with NOTICES
Total ...........................................
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Members of NCS target
(not NCS participants).
Average
burden hours
per response
Estimated total
annual burden
hours
2,100
1
0.08
175
population
700
1
0.17
117
population
700
1
0.25
175
population
700
1
0.08
58
population
700
1
0.50
350
population
700
1
1.00
700
population
700
2
0.50
700
population
700
1
0.25
175
population
700
2
0.25
350
population
700
28
0.05
980
population
700
1
1.00
700
population
700
1
0.08
58
population
700
1
0.50
350
population
700
72
0.03
1,680
population
700
1
0.03
23
population
700
1
0.75
525
population
700
1
0.50
350
...........................................................
700
........................
........................
7,467
Written comments and/or suggestions
from the public and affected agencies
are invited on one or more of the
following points: (1) Whether the
proposed collection of information is
necessary for the proper performance of
the function of the agency, including
19:08 Feb 16, 2012
Estimated
number of
responses per
respondent
population
Request for Comments
VerDate Mar<15>2010
Estimated
number of
respondents
Type of respondent
Jkt 226001
whether the information will have
practical utility; (2) The accuracy of the
agency’s estimate of the burden of the
proposed collection of information,
including the validity of the
methodology and assumptions used; (3)
Ways to minimize the burden of the
collection of information on those who
PO 00000
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Sfmt 4703
are to respond, including the use of
appropriate automated, electronic,
mechanical, or other technological
collection techniques or other forms of
information technology.
E:\FR\FM\17FEN1.SGM
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9668
Federal Register / Vol. 77, No. 33 / Friday, February 17, 2012 / Notices
For Further Information
To request more information on the
proposed project or to obtain a copy of
the data collection plans and
instruments, contact Dr. Sarah L.
Glavin, Deputy Director, Office of
Science Policy, Analysis and
Communication, National Institute of
Child Health and Human Development,
31 Center Drive Room 2A18, Bethesda,
Maryland, 20892, or call non-toll free
number (301) 496–1877 or Email your
request, including your address to
glavins@mail.nih.gov.
Comments Due Date
Comments regarding this information
collection are best assured of having
their full effect if received within 60
days of the date of this publication.
Dated: February 10, 2012.
Sarah L. Glavin,
Deputy Director, Office of Science Policy,
Analysis and Communications, National
Institute of Child Health and Human
Development.
[FR Doc. 2012–3809 Filed 2–16–12; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Government-Owned Inventions;
Availability for Licensing
National Institutes of Health,
Public Health Service, HHS.
AGENCY:
ACTION:
Notice.
The inventions listed below
are owned by an agency of the U.S.
Government and are available for
licensing in the U.S. in accordance with
35 U.S.C. 207 to achieve expeditious
commercialization of results of
federally-funded research and
development. Foreign patent
applications are filed on selected
inventions to extend market coverage
for companies and may also be available
for licensing.
SUMMARY:
Licensing information and
copies of the U.S. patent applications
listed below may be obtained by writing
to the indicated licensing contact at the
Office of Technology Transfer, National
Institutes of Health, 6011 Executive
Boulevard, Suite 325, Rockville,
Maryland 20852–3804; telephone: 301–
496–7057; fax: 301–402–0220. A signed
Confidential Disclosure Agreement will
be required to receive copies of the
patent applications.
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ADDRESSES:
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Selective Inhibitors of Polo-Like Kinase
1 (PLK1) Polo-Box Domains as Potential
Anticancer Agents
Description of Technology: PLK1 is a
regulator of cell growth that represents
a new target for anticancer therapeutic
development. High expression of PLK1
has been associated with several types
of cancer (e.g., breast cancer, prostate
cancer, ovarian cancer, non-small cell
lung carcinoma). Inhibiting PLK1 could
be an effective treatment for cancer
patients without significant side-effects.
Available for licensing are synthetic
peptides with the ability to bind to pololike kinase 1 (PLK1) polo-box domains
(PBDs) with selectivity and nanomolar
affinity and induce apoptosis in cancer
cells. By inhibiting the functions of
PLK1, these peptides could serve as
potential anti-cancer therapies. This
technology is related to and an
extension of HHS technology reference
E–181–2009.
Potential Commercial Applications:
• New anticancer therapies that
specifically target PLK1.
• Platform for the development of
further improved PLK1 inhibitors.
Competitive Advantages:
• High PBD binding affinity.
• High binding selectivity.
Development Stage: Early-stage.
Inventors: Terrence R. Burke, Jr. (NCI),
et al.
Publications:
1. Liu F, et al. Serendipitous
alkylation of a Plk1 ligand uncovers a
new binding channel. Nat Chem Biol.
2011 Jul 17;7(9):595–601. [PMID
21765407]
2. Qian W, et al. Investigation of
unanticipated alkylation at the N(pi)
position of a histidyl residue under
Mitsunobu conditions and synthesis of
orthogonally protected histidine
analogues. J Org Chem. 2011 Nov
4;76(21):8885–8890. [PMID 21950469]
Intellectual Property: HHS Reference
No. E–053–2012/0—U.S. Provisional
Application No. 61/588,470 filed 19 Jan
2012.
Related Technology: HHS Reference
No. E–181–2009/3—U.S. Provisional
Application No. 61/474,621 filed 12 Apr
2011.
Licensing Contact: Patrick McCue,
Ph.D.; 301–435–5560;
mccuepat@mail.nih.gov.
Influenza Vaccine
Description of Technology: It has been
shown that the fusion peptide, a
sequence comprised of fourteen amino
acids at the N-terminal of the influenza
hemagglutinin 2 protein is conserved
among A and B influenza viruses.
Monoclonal antibodies against this
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peptide are capable of binding all
influenza virus HA proteins and inhibit
viral growth by impeding the fusion
process between the virus and the target
cell. This application claims
immunogenic conjugates comprising the
fusion peptide region linked to a carrier
protein. In preclinical studies, these
conjugates were immunogenic and
induced booster responses. The induced
antibodies bound to the recombinant
HA protein. This methodology of
linking the highly conserved fusion
peptide region to a carrier protein can
broaden the protective immune
response to include influenza A and B
virus strains. This would eliminate the
need for annual influenza vaccination.
Potential Commercial Applications:
• Influenza vaccines
• Influenza diagnostics
• Research tools
Competitive Advantages:
• Universal influenza vaccine
• Efficient manufacturing process
• May eliminate need for yearly
influenza vaccination
Development Stage:
• Pre-clinical
• In vitro data available
• In vivo data available (animal)
Inventors: Joanna Kubler-Kielb, Jerry
M. Keith, Rachel Schneerson (NICHD).
Intellectual Property: HHS Reference
No. E–271–2011/0—U.S. Provisional
Application No. 61/541,942 filed 30 Sep
2011.
Licensing Contact: Peter A. Soukas,
J.D.; 301–435–4646; ps193c@nih.gov.
Collaborative Research Opportunity:
The NICHD is seeking statements of
capability or interest from parties
interested in collaborative research to
further develop, evaluate or
commercialize conjugate influenza
vaccines comprising fusion peptide
region. For collaboration opportunities,
please contact Joseph Conrad, Ph.D., J.D.
at 301–435–3107 or
jmconrad@mail.nih.gov.
ACSF3-Based Diagnostics and
Therapeutics for Combined Malonic
and Methylmalonic Aciduria
(CMAMMA) and Other Metabolic
Disorders
Description of Technology: Combined
malonic and methylmalonic aciduria
(CMAMMA) is a metabolic disorder in
which malonic acid and methylmalonic
acid, key intermediates in fatty acid
metabolism, accumulate in the blood
and urine. This disorder is often
undetected until symptoms manifest,
which can include developmental
delays and a failure to thrive in
children, and psychiatric and
neurological disorders in adults. Once
thought to be a very rare disease,
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[Federal Register Volume 77, Number 33 (Friday, February 17, 2012)]
[Notices]
[Pages 9666-9668]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2012-3809]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institute of Child Health and Human Development; New
Proposed Collection; Comment Request Stress and Cortisol Measurement
for the National Children's Study
Summary: In compliance with the requirement of Section
3506(c)(2)(A) of the Paperwork Reduction Act of 1995, for opportunity
for public comment on proposed data collection projects, the National
Institute of Child Health and Human Development (NICHD), the National
Institutes of Health (NIH) will publish periodic summaries of proposed
projects to be submitted to the Office of Management and Budget (OMB)
for review and approval.
Proposed Collection
Title: Stress and Cortisol Measurement Substudy for the National
Children's Study (NCS). Type of Information Collection Request: NEW.
Need and Use of Information Collection: The Children's Health Act of
2000 (Pub. L. 106-310) states:
(a) PURPOSE.--It is the purpose of this section to authorize the
National Institute of Child Health and Human Development to conduct
a national longitudinal study of environmental influences (including
physical, chemical, biological, and psychosocial) on children's
health and development.
(b) IN GENERAL.--The Director of the National Institute of Child
Health and Human Development shall establish a consortium of
representatives from appropriate Federal agencies (including the
Centers for Disease Control and Prevention, the Environmental
Protection Agency) to--
(1) Plan, develop, and implement a prospective cohort study,
from birth to adulthood, to evaluate the effects of both chronic and
intermittent exposures on child health and human development; and
(2) Investigate basic mechanisms of developmental disorders and
environmental factors, both risk and protective, that influence
health and developmental processes.
(c) REQUIREMENT.--The study under subsection (b) shall--
(1) Incorporate behavioral, emotional, educational, and
contextual consequences to enable a complete assessment of the
physical, chemical, biological, and psychosocial environmental
influences on children's well-being;
(2) Gather data on environmental influences and outcomes on
diverse populations of children, which may include the consideration
of prenatal exposures; and
(3) Consider health disparities among children, which may
include the consideration of prenatal exposures.
To fulfill the requirements of the Children's Health Act, the
Stress and Cortisol Measurement Substudy will develop an optimized,
item-reduced measure of self-reported stress that is supported
empirically through convergent validity analysis of stress biomarkers.
Specifically, key moderators of stress biomarkers will be evaluated to
inform the efficiency and quality of measurements during pregnancy.
Development of a scientifically robust maternal stress measure would
measure chronic stress more efficiently, would not require biospecimen
collection and biomarker analyses, and would thereby reduce participant
burden and NCS Vanguard (Pilot) and NCS Main Study costs. With this
information collection request, the NCS seeks to obtain OMB's clearance
to conduct a substudy aimed at developing a validated questionnaire
that will reflect specific biological and physiological measures of
maternal stress.
Background
The National Children's Study is a prospective, national
longitudinal study of the interaction between environment, genetics on
child health and development. The Study defines ``environment''
broadly, taking a number of natural and man-made environmental,
biological, genetic, and psychosocial factors into account. By studying
children through their different phases of growth and development,
researchers will be better able to understand the role these factors
have on health and disease. Findings from the Study will be made
available as the research progresses, making potential benefits known
to the public as soon as possible. The National Children's Study is led
by a consortium of federal partners: the U.S. Department of Health and
Human Services (https://www.hhs.gov/) (including the Eunice Kennedy
Shriver National Institute of Child Health and Human Development
(https://www.nichd.nih.gov/) and the National Institute of Environmental
Health Sciences (https://www.niehs.nih.gov/) of the National Institutes
of Health (https://www.nih.gov/) and the Centers for Disease Control
and Prevention (https://www.cdc.gov/)), and the U.S. Environmental
Protection Agency (https://www.epa.gov/).
To conduct the detailed preparation needed for a study of this size
and complexity, the NCS was designed to include a preliminary pilot
study known as the Vanguard Study. The purpose of the Vanguard Study is
to assess the feasibility, acceptability, and cost of the recruitment
strategy, study procedures, and outcome assessments that are to be used
in the NCS Main Study. The Vanguard Study begins prior to the NCS Main
Study and will run in parallel with the Main Study. At every phase of
the NCS, the multiple methodological studies conducted during the
Vanguard phase will inform the implementation and analysis plan for the
Main Study.
In this information collection request, the NCS requests approval
from OMB to perform a multi-center substudy, called the Stress and
Cortisol Measurement Substudy. This substudy aims to
[[Page 9667]]
determine the most reliable, acceptable, and cost-efficient approach
for assessing maternal stress. Maternal stress is of particular
interest to the NCS due to studies that have shown an association
between maternal stress and negative health outcomes, including preterm
birth which is one of the most important problems in maternal-child
health in the US. Stress factors are also more prevalent in the
population of socio-demographically disadvantaged women who are at an
increased risk for preterm birth. Maternal stress is associated with
additional health outcomes, such as still-birth, low birth weight,
problems in offspring brain function and behavior (including lower IQ
and impaired executive function), immune-related problems such as
allergies and asthma, congenital malformations, infections, and
numerous disorders of organ systems.
Development of a scientifically robust and validated questionnaire
to reflect specific physiological measures of stress would allow us to
measure chronic stress more efficiently, would not require biospecimen
collection and biomarker analyses, and would thereby reduce participant
burden and Study costs. To develop this instrument, the NCS will
collect several types of information from substudy participants through
medical record abstraction, questionnaires (a series of validated
stress measures), physiological measures (heart rate and self-reported
stress), and several types of biospecimens.
Frequency of Response: Annual [As needed].
Affected Public: Pregnant women and their children.
Type of Respondents: Pregnant women who are not geographically
eligible to enroll in the NCS Vanguard Study.
Annual Reporting Burden: See Table 1. The annualized cost to
respondents is estimated at: $74,677 (based on $10 per hour). There are
no Capital Costs to report. There are no Operating or Maintenance Costs
to report.
Table 1--Estimated Annual Reporting Burden Summary, Stress and Cortisol Measurements
----------------------------------------------------------------------------------------------------------------
Estimated
Type of Estimated number of Average Estimated
Data collection activity respondent number of responses per burden hours total annual
respondents respondent per response burden hours
----------------------------------------------------------------------------------------------------------------
Screening..................... Members of NCS 2,100 1 0.08 175
target
population (not
NCS
participants).
Consent....................... Members of NCS 700 1 0.17 117
target
population (not
NCS
participants).
Saliva Self-Collection Members of NCS 700 1 0.25 175
Demonstration. target
population (not
NCS
participants).
Urine Self-Collection Members of NCS 700 1 0.08 58
Instructions. target
population (not
NCS
participants).
Ecological Momentary Members of NCS 700 1 0.50 350
Assessment Training. target
population (not
NCS
participants).
Visit 1 Stress Questionnaire.. Members of NCS 700 1 1.00 700
target
population (not
NCS
participants).
Adult Blood................... Members of NCS 700 2 0.50 700
target
population (not
NCS
participants).
Adult Urine................... Members of NCS 700 1 0.25 175
target
population (not
NCS
participants).
Adult Hair.................... Members of NCS 700 2 0.25 350
target
population (not
NCS
participants).
Adult Saliva.................. Members of NCS 700 28 0.05 980
target
population (not
NCS
participants).
Demographic and Health Members of NCS 700 1 1.00 700
Interview. target
population (not
NCS
participants).
Participant Contact Members of NCS 700 1 0.08 58
Information Sheet. target
population (not
NCS
participants).
Take-Home Questionnaire....... Members of NCS 700 1 0.50 350
target
population (not
NCS
participants).
Time Diary.................... Members of NCS 700 72 0.03 1,680
target
population (not
NCS
participants).
Heart Monitoring.............. Members of NCS 700 1 0.03 23
target
population (not
NCS
participants).
Visit 2 Stress Questionnaire.. Members of NCS 700 1 0.75 525
target
population (not
NCS
participants).
Stressful Life Events Schedule Members of NCS 700 1 0.50 350
Checklist. target
population (not
NCS
participants).
---------------------------------------------------------------
Total..................... ................ 700 .............. .............. 7,467
----------------------------------------------------------------------------------------------------------------
Request for Comments
Written comments and/or suggestions from the public and affected
agencies are invited on one or more of the following points: (1)
Whether the proposed collection of information is necessary for the
proper performance of the function of the agency, including whether the
information will have practical utility; (2) The accuracy of the
agency's estimate of the burden of the proposed collection of
information, including the validity of the methodology and assumptions
used; (3) Ways to minimize the burden of the collection of information
on those who are to respond, including the use of appropriate
automated, electronic, mechanical, or other technological collection
techniques or other forms of information technology.
[[Page 9668]]
For Further Information
To request more information on the proposed project or to obtain a
copy of the data collection plans and instruments, contact Dr. Sarah L.
Glavin, Deputy Director, Office of Science Policy, Analysis and
Communication, National Institute of Child Health and Human
Development, 31 Center Drive Room 2A18, Bethesda, Maryland, 20892, or
call non-toll free number (301) 496-1877 or Email your request,
including your address to glavins@mail.nih.gov.
Comments Due Date
Comments regarding this information collection are best assured of
having their full effect if received within 60 days of the date of this
publication.
Dated: February 10, 2012.
Sarah L. Glavin,
Deputy Director, Office of Science Policy, Analysis and Communications,
National Institute of Child Health and Human Development.
[FR Doc. 2012-3809 Filed 2-16-12; 8:45 am]
BILLING CODE 4140-01-P
