National Center On Minority and Health Disparities Notice of Closed Meetings, 63310 [2011-26360]
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Federal Register / Vol. 76, No. 197 / Wednesday, October 12, 2011 / Notices
jlentini on DSK4TPTVN1PROD with NOTICES
human subject and was adapted to grow
in human hepatoma cells. The adapted
virus is unique in that it contains an
insertion of a portion of a human
ribosomal protein in Open Reading
Frame 1 of the virus. Desired exogenous
sequences could potentially be placed
in lieu of the insert without inactivating
the virus, making the subject technology
a prospective HEV vector platform.
Potential Commercial Applications:
• Vaccine—An infectious,
recombinant HEV genotype 3 cDNA
clone that could potentially be
developed into a vaccine candidate.
• HEV Vector Platform— Desired
exogenous sequences can be inserted
into the viral genome without
inactivating the virus.
Competitive Advantages:
• Most of the HEV vaccines under
development are subunit based while
the subject technology could potentially
be developed into a live, attenuated
virus based vaccine.
• Ability to insert exogenous
sequences into the viral genome without
inactivating the virus makes this subject
technology a potential HEV based vector
platform.
Development Stage:
• Early-stage
• Pre-clinical
• In vitro data available
Inventors: Suzanne U. Emerson,
Priyanka Shukla, Hanh T. Nguyen, and
Robert H. Purcell (NIAID).
Publication: Shukla P, et al. Crossspecies infections of cultured cells by
hepatitis E virus and discovery of an
infectious virus-host recombinant. Proc
Natl Acad Sci U S A. 2011 Feb
8;108(6):2438–2443. [PMID 21262830].
Intellectual Property: HHS Reference
No. E–074–2011/0—U.S. Provisional
Patent Application No. 61/431,377 filed
10 Jan 2011.
Licensing Contact: Kevin W. Chang,
PhD; 301–435–5018;
changke@mail.nih.gov.
Collaborative Research Opportunities:
The National Institute of Allergy and
Infectious Diseases is seeking statements
of capability or interest from parties
interested in collaborative research to
further develop, evaluate or
commercialize hepatitis E virus
vaccines. For collaboration
opportunities, please contact Wade
Green, PhD at 301–827–0258 or
williamswa@niaid.nih.gov.
Diagnostic H5N1 Avian Influenza Virus
Peptides
Description of Technology: The recent
spread of highly pathogenic H5N1 avian
influenza viruses among poultry and
transmission of these viruses to humans
raises concerns of a potential influenza
VerDate Mar<15>2010
17:43 Oct 11, 2011
Jkt 226001
pandemic. There is a need to track the
spread of these viruses both in the
animal and human populations to avert
or reduce the impact of any potential
influenza pandemic as well as to know
the actual number (accurate
surveillance) of people infected with
H5N1, including individuals with
subclinical H5N1 infection.
The subject technology is a specific
combination of H5N1 peptides useful
for assays to detect antibodies generated
against a wide range of different H5N1
strains. The combination of peptides
was able to specifically detect antiH5N1 antibodies from serum samples of
H5N1 survivors at early and later times
post infection while excluding
antibodies generated in individuals
infected with other strains of influenza
virus. Also, the peptides did not react
with sera from individuals vaccinated
with H5N1 vaccine, in contrast to the
strain-specific detection of anti-H5N1
antibodies in sera from infected
individuals. Immunoassays using the
H5N1 peptide combination provide
highly specific, sensitive and
reproducible methods for diagnosing
H5N1 infection in humans and animals.
Potential Commercial Applications:
Diagnostics for influenza virus specific
antibodies in humans and animals.
Competitive Advantages: High
specificity, sensitivity, and
reproducibility.
Development Stage: Data obtained
from clinical samples can be provided
upon request.
Inventors: Hana Golding and Surender
Khurana (FDA).
Intellectual Property: HHS Reference
No. E–093–2010/0—PCT Application
No. PCT/US2011/032555 filed 14 Apr
2011.
Related Technology: HHS Reference
No. E–236–2007/3—U.S. Patent
Application No. 12/664,052 filed 10 Dec
2008.
Licensing Contact: Kevin W. Chang,
PhD; 301–435–5018;
changke@mail.nih.gov.
Dated: October 4, 2011.
Richard U. Rodriguez,
Director, Division of Technology Development
and Transfer, Office of Technology Transfer,
National Institutes of Health.
[FR Doc. 2011–26338 Filed 10–11–11; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Center On Minority and Health
Disparities Notice of Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App), notice is
hereby given of the following meetings.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable materials,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Center on
Minority Health and Health Disparities
Special Emphasis Panel; NIMHD Health
Disparities Research (R01).
Date: November 7–8, 2011.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: Gaithersburg Marriott Washington
Center, 9751 Washingtonian Boulevard,
Gaithersburg, MD 20878.
Contact Person: Maryline Laude-Sharp,
PhD, Scientific Review Officer, National
Institute on Minority Health and Health
Disparities, National Institutes of Health,
6707 Democracy Blvd., MSC. 5465, Suite
800, Bethesda, MD 20892, (301) 451–9536,
mlaudesharp@mail.nih.gov.
Name of Committee: National Center on
Minority Health and Health Disparities
Special Emphasis Panel; NIMHD Support for
Conference and Scientific meetings (R13)
2012.
Date: November 14, 2011.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, Two
Democracy Plaza, 6707 Democracy Blvd.,
Bethesda, MD 20892 (Virtual Meeting).
Contact Person: Maryline Laude-Sharp,
PhD, Scientific Review Officer, National
Institute on Minority Health and Health
Disparities, National Institutes of Health,
6707 Democracy Blvd., MSC. 5465, Suite
800, Bethesda, MD 20892, (301) 451–9536,
mlaudesharp@mail.nih.gov.
Dated: October 5, 2011.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 2011–26360 Filed 10–11–11; 8:45 am]
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[Federal Register Volume 76, Number 197 (Wednesday, October 12, 2011)]
[Notices]
[Page 63310]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-26360]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Center On Minority and Health Disparities Notice of
Closed Meetings
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. App), notice is hereby given of the following
meetings.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable materials, and personal information concerning individuals
associated with the grant applications, the disclosure of which would
constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: National Center on Minority Health and Health
Disparities Special Emphasis Panel; NIMHD Health Disparities
Research (R01).
Date: November 7-8, 2011.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant applications.
Place: Gaithersburg Marriott Washington Center, 9751
Washingtonian Boulevard, Gaithersburg, MD 20878.
Contact Person: Maryline Laude-Sharp, PhD, Scientific Review
Officer, National Institute on Minority Health and Health
Disparities, National Institutes of Health, 6707 Democracy Blvd.,
MSC. 5465, Suite 800, Bethesda, MD 20892, (301) 451-9536,
mlaudesharp@mail.nih.gov.
Name of Committee: National Center on Minority Health and Health
Disparities Special Emphasis Panel; NIMHD Support for Conference and
Scientific meetings (R13) 2012.
Date: November 14, 2011.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, Two Democracy Plaza, 6707
Democracy Blvd., Bethesda, MD 20892 (Virtual Meeting).
Contact Person: Maryline Laude-Sharp, PhD, Scientific Review
Officer, National Institute on Minority Health and Health
Disparities, National Institutes of Health, 6707 Democracy Blvd.,
MSC. 5465, Suite 800, Bethesda, MD 20892, (301) 451-9536,
mlaudesharp@mail.nih.gov.
Dated: October 5, 2011.
Jennifer S. Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 2011-26360 Filed 10-11-11; 8:45 am]
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