Center for Scientific Review; Notice of Closed Meeting, 52958-52959 [2011-21681]
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52958
Federal Register / Vol. 76, No. 164 / Wednesday, August 24, 2011 / Notices
SUPPLEMENTARY INFORMATION:
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2011–D–0587]
Draft Guidance for Industry on
Neglected Tropical Diseases of the
Developing World: Developing Drugs
for Treatment or Prevention;
Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is announcing the
availability of a draft guidance for
industry entitled ‘‘Neglected Tropical
Diseases of the Developing World:
Developing Drugs for Treatment or
Prevention.’’ The purpose of this
guidance is to assist sponsors in the
clinical development of drugs for the
treatment or prevention of neglected
diseases of the developing world.
Specifically, this guidance addresses
FDA’s current thinking regarding the
overall drug development program for
the treatment or prevention of neglected
tropical diseases (NTDs), including
clinical trial designs and internal review
standards to support approval of drugs.
DATES: Although you can comment on
any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency
considers your comment on this draft
guidance before it begins work on the
final version of the guidance, submit
either electronic or written comments
on the draft guidance by November 22,
2011.
ADDRESSES: Submit written requests for
single copies of the draft guidance to the
Division of Drug Information, Center for
Drug Evaluation and Research, Food
and Drug Administration, 10903 New
Hampshire Ave., Bldg. 51, rm. 2201,
Silver Spring, MD 20993–0002. Send
one self-addressed adhesive label to
assist that office in processing your
requests. See the SUPPLEMENTARY
INFORMATION section for electronic
access to the draft guidance document.
Submit electronic comments on the
draft guidance to https://
www.regulations.gov. Submit written
comments to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, rm.
1061, Rockville, MD 20852.
FOR FURTHER INFORMATION CONTACT:
Joseph G. Toerner, Center for Drug
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 22, rm. 6244,
Silver Spring, MD 20993–0002, 301–
796–1300.
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SUMMARY:
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I. Background
FDA is announcing the availability of
a draft guidance for industry entitled
‘‘Neglected Tropical Diseases of the
Developing World: Developing Drugs for
Treatment or Prevention.’’ This
guidance addresses section 740 of the
Agriculture, Rural Development, Food
and Drug Administration and Related
Agencies Appropriations Act, 2010
(Pub. L. 111–80), dated October 21,
2009, that directed FDA to provide
guidance in the form of general
recommendations and regulatory
considerations for drugs being
developed for the treatment or
prevention of NTDs. NTDs, as defined
in section 524(a)(3) of the Federal Food,
Drug, and Cosmetic Act (21 U.S.C.
360n(a)(3)), are infectious diseases that
generally are rare or absent in developed
countries, but are often widespread in
developing countries. The availability of
new drugs that are safe and effective for
treatment or prevention of NTDs could
provide public health benefit for overall
global health.
The purpose of this draft guidance is
to provide recommendations to
sponsors and investigators who are
involved in the development of drugs
for the treatment or prevention of NTDs.
This guidance is intended to clarify the
regulatory requirements for drug
approval in the United States as well as
the internal review standards for drugs
for NTDs. This guidance is directed at
sponsors who lack general knowledge
about drug development issues.
Potential sponsors should understand
that: (1) FDA will review and comment
on clinical development programs for
NTDs under an investigational new drug
application submission, regardless of
where the clinical development will
take place; (2) FDA can approve a drug
for treatment of an NTD not endemic in
the United States; (3) the regulatory
pathways and internal review standards
for approval of drugs for NTDs are the
same as for approval of drugs for
diseases endemic in the United States;
and (4) FDA is committed to exercising
its regulatory authorities to facilitate
access to therapies that can help reduce
morbidity and mortality associated with
NTDs.
This draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the Agency’s current thinking
on this topic. It does not create or confer
any rights for or on any person and does
not operate to bind FDA or the public.
An alternative approach may be used if
such approach satisfies the
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requirements of the applicable statutes
and regulations.
II. The Paperwork Reduction Act of
1995
This guidance refers to previously
approved collections of information that
are subject to review by the Office of
Management and Budget (OMB) under
the Paperwork Reduction Act of 1995
(44 U.S.C. 3501–3520). The collections
of information in 21 CFR part 312 have
been approved under OMB control
number 0910–0014.
III. Comments
Interested persons may submit to the
Division of Dockets Management (see
ADDRESSES) either electronic or written
comments regarding this document. It is
only necessary to send one set of
comments. It is no longer necessary to
send two copies of mailed comments.
Identify comments with the docket
number found in brackets in the
heading of this document. Received
comments may be seen in the Division
of Dockets Management between 9 a.m.
and 4 p.m., Monday through Friday.
IV. Electronic Access
Persons with access to the Internet
may obtain the document at either
https://www.fda.gov/Drugs/
GuidanceCompliance
RegulatoryInformation/Guidances/
default.htm or https://
www.regulations.gov.
Dated: August 18, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
[FR Doc. 2011–21630 Filed 8–23–11; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Notice of
Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
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Federal Register / Vol. 76, No. 164 / Wednesday, August 24, 2011 / Notices
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Center for Scientific
Review Special Emphasis Panel, Member
Conflict: Risk Prevention and Health
Behavior.
Date: September 13, 2011.
Time: 11 a.m. to 1:30 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892,
(Telephone Conference Call).
Contact Person: Rebecca Henry, PhD,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 3222,
MSC 7808, Bethesda, MD 20892, 301–435–
1717, henryrr@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.306, Comparative Medicine;
93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393–93.396, 93.837–93.844,
93.846–93.878, 93.892, 93.893, National
Institutes of Health, HHS)
Dated: August 18, 2011.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
6707 Democracy Boulevard, Suite 800,
Bethesda, MD 20892, (301) 496–3996,
netteyr@mail.nih.gov.
This notice is being published less than 15
days prior to the meeting due to the timing
limitations imposed by the review and
funding cycle.
Name of Committee: National Center on
Minority Health and Health Disparities
Special Emphasis Panel; NIMHD Revision
Applications to Support Environmental
Health Disparities Research (P60).
Date: August 29, 2011.
Time: 12 p.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: Bethesda Marriott Suites, 6711
Democracy Boulevard, Bethesda, MD 20817.
Contact Person: Robert Nettey, MD, Chief,
Scientific Review Officer, National Institute
on Minority Health, and Health Disparities,
6707 Democracy Boulevard, Suite 800,
Bethesda, MD 20892, (301) 496–3996,
netteyr@mail.nih.gov.
This notice is being published less than 15
days prior to the meeting due to the timing
limitations imposed by the review and
funding cycle.
Dated: August 18, 2011.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 2011–21681 Filed 8–23–11; 8:45 am]
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[FR Doc. 2011–21680 Filed 8–23–11; 8:45 am]
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
BILLING CODE 4140–01–P
National Institutes of Health
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Center on Minority and Health
Disparities; Notice of Closed Meetings
National Institutes of Health
wreier-aviles on DSKGBLS3C1PROD with NOTICES
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable materials,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Center on
Minority Health and Health Disparities
Special Emphasis Panel; NIMHD Revision
Applications to Support Environmental
Health Disparities Research P20.
Date: August 29, 2011.
Time: 8 a.m. to 12 p.m.
Agenda: To review and evaluate grant
applications.
Place: Bethesda Marriott Suites, 6711
Democracy Boulevard, Bethesda, MD 20817.
Contact Person: Robert Nettey, MD, Chief,
Scientific Review Officer, National Institute
on Minority Health and Health Disparities,
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Center for Scientific Review; Notice of
Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Center for Scientific
Review Special Emphasis Panel,
Neurodegeneration and Stroke Special
Emphasis Panel.
Date: September 21, 2011.
Time: 2 to 4 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892,
(Telephone Conference Call).
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Contact Person: Jay Joshi, PhD, Scientific
Review Officer, Center for Scientific Review,
National Institutes of Health, 6701 Rockledge
Drive, Room 5196, MSC 7846, Bethesda, MD
20892, (301) 408–9135, joshij@csr.nih.gov.
Name of Committee: Risk, Prevention and
Health Behavior Integrated Review Group,
Risk, Prevention and Intervention for
Addictions Study Section.
Date: September 29–30, 2011.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: Mayflower Renaissance,
Washington, DC 20236.
Contact Person: Gabriel B Fosu, PhD,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 3108,
MSC 7808, Bethesda, MD 20892, (301) 435–
3562, fosug@csr.nih.gov.
Name of Committee: Immunology
Integrated Review Group, Transplantation,
Tolerance, and Tumor Immunology Study
Section.
Date: September 29–30, 2011.
Time: 8 a.m. to 4 p.m.
Agenda: To review and evaluate grant
applications.
Place: Washington Plaza Hotel, 10 Thomas
Circle, NW., Washington, DC 20005.
Contact Person: Jin Huang, PhD, Scientific
Review Officer, Center for Scientific Review,
National Institutes of Health, 6701 Rockledge
Drive, Room 4199, MSC 7812, Bethesda, MD
20892, 301–435–1230, jh377p@nih.gov.
Name of Committee: Genes, Genomes, and
Genetics Integrated Review Group, Molecular
Genetics B Study Section.
Date: September 29–30, 2011.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: Fairmont Hotel San Francisco, 950
Mason Street, San Francisco, CA 94108.
Contact Person: Richard A Currie, PhD,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 5128,
MSC 7840, Bethesda, MD 20892, (301) 435–
1219, currieri@csr.nih.gov.
Name of Committee: Risk, Prevention and
Health Behavior Integrated Review Group,
Psychosocial Development, Risk and
Prevention Study Section.
Date: September 29–30, 2011.
Time: 8 a.m. to 6 p.m.
Agenda: To review and evaluate grant
applications.
Place: The Fairmont Washington, DC, 2401
M Street, NW., Washington, DC 20037.
Contact Person: Anna L Riley, PhD,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 3114,
MSC 7759, Bethesda, MD 20892, 301–435–
2889, rileyann@csr.nih.gov.
Name of Committee: Center for Scientific
Review Special Emphasis Panel, Chromatin
Program Projects.
Date: September 29, 2011.
Time: 8:30 a.m. to 6 p.m.
Agenda: To review and evaluate grant
applications.
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Agencies
[Federal Register Volume 76, Number 164 (Wednesday, August 24, 2011)]
[Notices]
[Pages 52958-52959]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-21681]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Notice of Closed Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is hereby given of the following
meeting.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications, the disclosure of which
[[Page 52959]]
would constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: Center for Scientific Review Special Emphasis
Panel, Member Conflict: Risk Prevention and Health Behavior.
Date: September 13, 2011.
Time: 11 a.m. to 1:30 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, 6701 Rockledge Drive,
Bethesda, MD 20892, (Telephone Conference Call).
Contact Person: Rebecca Henry, PhD, Scientific Review Officer,
Center for Scientific Review, National Institutes of Health, 6701
Rockledge Drive, Room 3222, MSC 7808, Bethesda, MD 20892, 301-435-
1717, henryrr@mail.nih.gov.
(Catalogue of Federal Domestic Assistance Program Nos. 93.306,
Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393-93.396, 93.837-93.844, 93.846-93.878, 93.892, 93.893,
National Institutes of Health, HHS)
Dated: August 18, 2011.
Jennifer S. Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 2011-21681 Filed 8-23-11; 8:45 am]
BILLING CODE 4140-01-P