Agency Information Collection Activities; Announcement of Office of Management and Budget Approval; Restaurant Menu and Vending Machine Labeling: Recordkeeping and Mandatory Third Party Disclosure Under Section 4205 of the Patient Protection and Affordable Care Act of 2010, 41265-41266 [2011-17571]
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41265
Federal Register / Vol. 76, No. 134 / Wednesday, July 13, 2011 / Notices
docket number found in brackets in the
heading of this document.
FOR FURTHER INFORMATION CONTACT:
Juanmanuel Vilela, Office of
Information Management, Food and
Drug Administration, 1350 Piccard Dr.,
PI50–400B, Rockville, MD 20850, 301–
796–7651,
Juanmanuel.vilela@fda.hhs.gov.
Under the
PRA (44 U.S.C. 3501–3520), Federal
Agencies must obtain approval from the
Office of Management and Budget
(OMB) for each collection of
information they conduct or sponsor.
‘‘Collection of information’’ is defined
in 44 U.S.C. 3502(3) and 5 CFR
1320.3(c) and includes Agency requests
or requirements that members of the
public submit reports, keep records, or
provide information to a third party.
Section 3506(c)(2)(A) of the PRA (44
U.S.C. 3506(c)(2)(A)) requires Federal
Agencies to provide a 60-day notice in
the Federal Register concerning each
proposed collection of information,
including each proposed extension of an
existing collection of information,
before submitting the collection to OMB
for approval. To comply with this
requirement, FDA is publishing notice
SUPPLEMENTARY INFORMATION:
of the proposed collection of
information set forth in this document.
With respect to the following
collection of information, FDA invites
comments on these topics: (1) Whether
the proposed collection of information
is necessary for the proper performance
of FDA’s functions, including whether
the information will have practical
utility; (2) the accuracy of FDA’s
estimate of the burden of the proposed
collection of information, including the
validity of the methodology and
assumptions used; (3) ways to enhance
the quality, utility, and clarity of the
information to be collected; and (4)
ways to minimize the burden of the
collection of information on
respondents, including through the use
of automated collection techniques,
when appropriate, and other forms of
information technology.
Appeals of Science-Based Decisions
Above the Division Level at CVM—21
CFR Part 10.75 (OMB Control Number
0910–0566—Extension)
Respondents: Respondents to this
collection of information are applicants
that wish to submit a request for review
of a scientific dispute.
CVM’s Guidance for Industry #79—
‘‘Dispute Resolution Procedures for
Science-based Decisions on Products
Regulated by the Center for Veterinary
Medicine’’ describes the process by
which CVM formally resolves disputes
relating to scientific controversies. A
scientific controversy involves issues
concerning a specific product regulated
by CVM related to matters of technical
expertise and requires specialized
education, training, or experience to be
understood and resolved. Further, the
guidance details information on how the
Agency intends to interpret and apply
provisions of the existing regulations
regarding internal Agency review of
decisions. In addition, the guidance
outlines the established procedures for
persons who are sponsors, applicants, or
manufacturers, for animal drugs or other
products regulated by CVM, who wish
to submit a request for review of a
scientific dispute. When a sponsor,
applicant, or manufacturer has a
scientific disagreement with a written
decision by CVM, they may submit a
request for a review of that decision by
following the established Agency
channels of supervision for review.
FDA estimates the burden of this
collection of information as follows:
TABLE 1—ESTIMATED ANNUAL REPORTING BURDEN 1
10.75 ....................................................................................
1 There
1
Average
burden per
response
Total annual
responses
3
3
Total hours
10
30
are no capital costs or operating and maintenance costs associated with this collection of information.
This estimated annual reporting
burden is based on CVM’s experience
over the past 3 years in handling formal
appeals for scientific disputes. The
number of respondents multiplied by
the number of responses per respondent
equals the total annual responses. The
average burden per response (in hours)
is based on discussions with industry
and may vary depending on the
complexity of the issue(s) involved and
the duration of the appeal process.
Dated: July 7, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
[FR Doc. 2011–17532 Filed 7–12–11; 8:45 am]
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Number of responses per
respondent
Number of
respondents
21 CFR section
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2010–N–0567]
Agency Information Collection
Activities; Announcement of Office of
Management and Budget Approval;
Restaurant Menu and Vending Machine
Labeling: Recordkeeping and
Mandatory Third Party Disclosure
Under Section 4205 of the Patient
Protection and Affordable Care Act of
2010
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is announcing
that a collection of information entitled
‘‘Restaurant Menu and Vending
Machine Labeling: Recordkeeping and
Mandatory Third Party Disclosure
SUMMARY:
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17:36 Jul 12, 2011
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Under Section 4205 of the Patient
Protection and Affordable Care Act of
2010’’ has been approved by the Office
of Management and Budget (OMB)
under the Paperwork Reduction Act of
1995.
FOR FURTHER INFORMATION CONTACT:
Denver Presley, Jr., Office of Information
Management, Food and Drug
Administration, 1350 Piccard Dr., PI50–
400B, Rockville, MD 20850, 301–796–
3793.
In the
Federal Register of January 31, 2011
(76 FR 5380), the Agency announced
that the proposed information collection
had been submitted to OMB for review
and clearance under 44 U.S.C. 3507. An
Agency may not conduct or sponsor,
and a person is not required to respond
to, a collection of information unless it
displays a currently valid OMB control
number. OMB has now approved the
information collection and has assigned
OMB control number 0910–0665. The
SUPPLEMENTARY INFORMATION:
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Federal Register / Vol. 76, No. 134 / Wednesday, July 13, 2011 / Notices
approval expires on June 13, 2014. A
copy of the supporting statement for this
information collection is available on
the Internet at https://www.reginfo.gov/
public/do/PRAMain.
Dated: July 7, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
[FR Doc. 2011–17571 Filed 7–12–11; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
I. Funding Opportunity Description
Funding Opportunity Number: RFA–
FD–11–014.
Catalog of Federal Domestic
Assistance: 93.103.
Food and Drug Administration
[Docket No. FDA–2011–N–0012]
Critical Path Manufacturing Sector
Research Initiative (U01)
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is announcing the
availability of grant funds for the
support of a cooperative agreement with
the National Institute for
Pharmaceutical Technology and
Education Initiative (NIPTE).
Development of the Critical Path
Manufacturing Sector Initiative has
focused attention on the continuing
need for this kind of research in a way
that can improve reliability of
pharmaceutical product manufacturing
and quality across the entire industry.
This shared knowledge will increase the
likelihood of successfully
manufacturing products that have been
identified in the clinical development
community. The goal of this agreement
is to improve the overall manufacturing
and quality and the knowledge base.
DATES: Important dates are as follows:
1. The application due date is July 20,
2011.
2. The anticipated start date is August
31, 2011.
3. The opening date is July 13, 2011.
4. The expiration date is July 22,
2011.
For Further Information and
Additional Requirements Contact:
For Programmatic and Scientific
Questions and Concerns contact:
Jon Clark, Center for Drug Evaluation
and Research, Food and Drug
Administration, 10903 New Hampshire
Ave., Bldg. 51, rm. 4178, Silver Spring,
MD 20993, 301–796–2400; E-mail:
Jon.Clark@fda.hhs.gov.
For Administrative and Financial
Questions and Concerns contact: Gladys
Melendez, Office of Acquisitions and
Grant Support, Food and Drug
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SUMMARY:
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17:36 Jul 12, 2011
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Administration, 5630 Fishers Lane, rm.
1078, Rockville, MD 20857, 301–827–
7175; E-mail: gmb@fda.hhs.gov.
For more information on this funding
opportunity announcement (FOA) and
to obtain detailed requirements, please
refer to the full FOA located at https://
www.fda.gov/AboutFDA/CentersOffices/
CDER/ucm088761.htm under the
‘‘Regulatory Information’’ section. The
title of the page is ‘‘Research
Acquisitions.’’
SUPPLEMENTARY INFORMATION:
A. Background
The Office of Pharmaceutical Science
has conducted research within the
academic community through contracts
in order to improve the overall
manufacturing and quality knowledge
base. This research is important to the
public sector, because research
conducted in pharmaceutical sciences
related to product quality is typically
kept proprietary.
Development of the Critical Path
Manufacturing Sector Initiative has
focused attention on the continuing
need for this kind of research in a way
that can improve reliability of
pharmaceutical product manufacturing
and quality across the entire industry.
This shared knowledge will increase the
likelihood of successful manufacturing.
B. Research Objectives
The grant will support programs and
research as described in the following
paragraphs, related to the manufacturing
of drugs, biological products, and
medical devices:
• Education and training in the field
of manufacturing and scale-up, for
product development partnerships,
academic scientists, other product
developers and product application
reviewers.
• Development of platform strategies
and standardized approaches for
medical product manufacturing to
shorten timelines for manufacturers to
produce quality medical products at
commercial scale. This will provide
publicly available models for
manufacturing and scale-up that will
help enable small firms to expeditiously
market important treatments.
• Development of analytical
methodologies and advanced
computational methodologies to better
characterize complex molecules and
complex mixtures of molecules is
needed to better understand and control
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manufacturing processes and product
quality. Specific analytical techniques
will better enable standardized
approaches to manufacturing control
and advance computational
technologies will help to identify
atypical samples of complex molecules.
These advances will help assure
pharmaceutical quality for the American
public.
• Research into improved techniques
for collection and analysis of process
data to control processes and to ensure
that they are in statistical control will be
done. This includes science-based
flexible and adaptive approaches to
manufacturing utilizing feed forward
and feed backward information flow.
Standardized approaches to assuring
product quality using manufacturing
and analytical data will support
continued product quality and lessen
manufacturing failures thus decreasing
shortages of medically necessary
products.
• Development of techniques for
assuring product quality using
surrogates for desired clinical results
will improve understanding of quality
target product profile. This approach
takes advantage of the potential to use
existing clinical data to determine
clinically relevant specifications
including unit-to-unit variability, drug
dissolution, and other material or
product attributes, and to support future
manufacturing improvements while
maintaining product quality.
• Creating simulation models for
manufacturing techniques including but
not limited to biotech fermentation and
cell culture, small molecule
crystallization, freeze drying techniques,
and precision tablet coating will
enhance industry knowledge. These
models will enable a more predictable
approach to manufacturing
development and design of control
systems. This predictability will shorten
the critical path pipeline from
laboratory to clinic and support
continual improvement to achieve
product quality of the drug’s lifecycle.
• Creating simulation models for
complex drug delivery devices such as
dry product inhalers, transdermal
patches, and liposomal products to
better understand the product design
and performance and to control the
critical manufacturing parameters.
These models will aid to speed the
development of novel dosage forms and
decrease the failure rates of these
products.
• Research into product formulation
for special patient populations or
product formulation to ensure chemical
stability of active ingredients will
shorten formulation development and
E:\FR\FM\13JYN1.SGM
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Agencies
[Federal Register Volume 76, Number 134 (Wednesday, July 13, 2011)]
[Notices]
[Pages 41265-41266]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-17571]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2010-N-0567]
Agency Information Collection Activities; Announcement of Office
of Management and Budget Approval; Restaurant Menu and Vending Machine
Labeling: Recordkeeping and Mandatory Third Party Disclosure Under
Section 4205 of the Patient Protection and Affordable Care Act of 2010
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is announcing that a
collection of information entitled ``Restaurant Menu and Vending
Machine Labeling: Recordkeeping and Mandatory Third Party Disclosure
Under Section 4205 of the Patient Protection and Affordable Care Act of
2010'' has been approved by the Office of Management and Budget (OMB)
under the Paperwork Reduction Act of 1995.
FOR FURTHER INFORMATION CONTACT: Denver Presley, Jr., Office of
Information Management, Food and Drug Administration, 1350 Piccard Dr.,
PI50-400B, Rockville, MD 20850, 301-796-3793.
SUPPLEMENTARY INFORMATION: In the Federal Register of January 31, 2011
(76 FR 5380), the Agency announced that the proposed information
collection had been submitted to OMB for review and clearance under 44
U.S.C. 3507. An Agency may not conduct or sponsor, and a person is not
required to respond to, a collection of information unless it displays
a currently valid OMB control number. OMB has now approved the
information collection and has assigned OMB control number 0910-0665.
The
[[Page 41266]]
approval expires on June 13, 2014. A copy of the supporting statement
for this information collection is available on the Internet at https://www.reginfo.gov/public/do/PRAMain.
Dated: July 7, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
[FR Doc. 2011-17571 Filed 7-12-11; 8:45 am]
BILLING CODE 4160-01-P