National Center for Research Resources; Notice of Closed Meetings, 40384-40385 [2011-17214]

Download as PDF 40384 Federal Register / Vol. 76, No. 131 / Friday, July 8, 2011 / Notices mstockstill on DSK4VPTVN1PROD with NOTICES Patent Status: HHS Reference No. E– 175–2011/0 —Research Tool. Patent protection is not being pursued for this technology. Licensing Status: Available for licensing under a Biological Materials License Agreement. Licensing Contact: Betty B. Tong, PhD; 301–594–6565; tongb@mail.nih.gov. Collaborative Research Opportunity: The NIEHS Laboratory of Signal Transduction is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize these mice or other strains derived from them, or cells or other reagents derived from them. Please contact Dr. Elizabeth Denholm (denholme@niehs.nih.gov) in the NIEHS Office of Technology Transfer, or the Inventor Dr. Perry Blackshear (black009@niehs.nih.gov) for more information. Inhibitors of Human Apurinic/ Apyrimidinic Endonuclease 1 (APE1), an Anticancer Drug Target Description of Technology: APE1 is the primary mammalian enzyme responsible for the removal of abasic (AP sites) in DNA and functions as part of the base excision DNA repair pathway (BER). BER is instrumental in the repair of DNA damage caused by DNA alkylating agents (e.g. many cancer chemotherapeutics). APE1 has been shown to be overexpressed in cancer cells. It has been postulated that APE1 would be an attractive target in anticancer treatment paradigms; preclinical and clinical data confirm that APE1 is a valid anticancer drug target. To date, only one APE1 small molecule inhibitor has progressed to clinical trials (methoxyamine hydrochloride), and this compound inhibits a wide range of repair processes, which could result in undesired side-effects. The NIH inventors now report the discovery of a novel APE1 small molecule inhibitor, which exhibits potent in vitro activity, potentiates the cytotoxicity of DNA damaging agents (alkylators methylmethane sulfonate and Temozolomide), results in the accumulation of AP sites, and has favorable pharmacokinetic properties. The inventors plan to carry out further studies in mouse tumor xenograft models. Applications: Cancer therapeutics as single agent as well as in combination therapy. Development Status: In vivo pharmacokinetics data on lead compounds available. VerDate Mar<15>2010 17:52 Jul 07, 2011 Jkt 223001 Inventors: David J. Maloney, et al. (NHGRI). Publication: Manuscript submitted. Patent Status: U.S. Provisional Patent Application No. 61/480,145 filed April 28, 2011 (HHS Reference No. E–094– 2011/0–US–01). Licensing Status: Available for licensing. Licensing Contact: Betty B. Tong, PhD; 301–594–6565; tongb@mail.nih.gov. Collaborative Research Opportunity: The NIH Center for Translational Therapeutics, NHGRI is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize the above technology. Please contact Lili Portilla, Acting Director of Technology Transfer and Partnerships, NCTT at Lilip@nih.gov for more information. Dated: July 1, 2011. Richard U. Rodriguez, Director, Division of Technology Development and Transfer, Office of Technology Transfer, National Institutes of Health. Bethesda, MD 20892. (301) 496–3996. netteyr@mail.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. Name of Committee: National Center on Minority Health and Health Disparities Special Emphasis Panel, R13 Review. Date: July 13, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6707 Democracy Boulevard, Suite 800, Bethesda, MD 20892. (Virtual Meeting.) Contact Person: Robert Nettey, M.D., Chief, Scientific Review Officer, National Institute on Minority Health and Health Disparities, 6707 Democracy Boulevard, Suite 800, Bethesda, MD 20892. (301) 496–3996. netteyr@mail.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. Dated: July 1, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. 2011–17227 Filed 7–7–11; 8:45 am] [FR Doc. 2011–17225 Filed 7–7–11; 8:45 am] BILLING CODE 4140–01–P BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institutes of Health National Center on Minority and Health Disparities; Notice of Closed Meeting National Center for Research Resources; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable materials, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Center on Minority Health and Health Disparities Special, Emphasis Panel, U24 Grant Review. Date: July 11–12, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Hilton Washington/Rockville, 1750 Rockville Pike, Rockville, MD 20852. Contact Person: Robert Nettey, M.D., Chief, Scientific Review Officer, National Institute on Minority Health and Health Disparities, 6707 Democracy Boulevard, Suite 800, Name of Committee: National Center for Research Resources Special Emphasis Panel, NCRR Animal Resource. Date: July 28, 2011. Time: 1 to 2 p.m. Agenda: To review and evaluate grant applications, Place: National Institutes of Health/NCRR/ OR, Democracy 1, 6701 Democracy Blvd., 1078, Bethesda, MD 20892. Contact Person: Lee Warren Slice, PhD, Scientific Review Officer, Office of Review, National Center for Research Resources, 6701 PO 00000 Frm 00063 Fmt 4703 Sfmt 4703 E:\FR\FM\08JYN1.SGM 08JYN1 Federal Register / Vol. 76, No. 131 / Friday, July 8, 2011 / Notices Democracy Blvd., Room 1068, Bethesda, MD 20892, 301–435–0965, slicelw@mail.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical Technology; 93.389, Research Infrastructure, 93.306, 93.333; 93.702, ARRA Related Construction Awards, National Institutes of Health, HHS) Dated: July 1, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. Dated: July 1, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. 2011–17206 Filed 7–7–11; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services [FR Doc. 2011–17214 Filed 7–7–11; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency Information Collection Activities: Form I–907, Extension of a Currently Approved Information Collection; Comment Request National Institutes of Health ACTION: 30-Day notice of information collection under review: form I–907, request for premium processing service. National Institute of Arthritis and Musculoskeletal and Skin Diseases Notice of Closed Meeting mstockstill on DSK4VPTVN1PROD with NOTICES Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Arthritis and Musculoskeletal and Skin Diseases, Special Emphasis Panel, Ancillary Studies to Large Ongoing Clinical Projects Grant Review. Date: July 20, 2011. Time: 10 a.m. to 11 a.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, One Democracy Plaza, 6701 Democracy Boulevard, Suite 800, Bethesda, MD 20892. (Telephone Conference Call.) Contact Person: Charles H Washabaugh, PhD, Scientific Review Officer, Scientific Review Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, 6701 Democracy Blvd, Suite 800, Bethesda, MD 20817. 301–594–4952. washabac@mail.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.846, Arthritis, Musculoskeletal and Skin Diseases Research, National Institutes of Health, HHS) VerDate Mar<15>2010 17:52 Jul 07, 2011 Jkt 223001 The Department of Homeland Security, U.S. Citizenship and Immigration Services (USCIS) will be submitting the following information collection request to the Office of Management and Budget (OMB) for review and clearance in accordance with the Paperwork Reduction Act of 1995. The information collection was previously published in the Federal Register on April 12, 2011, at 76 FR 20361, allowing for a 60-day public comment period. USCIS did not receive any comments. The purpose of this notice is to allow an additional 30 days for public comments. Comments are encouraged and will be accepted until August 8, 2011. This process is conducted in accordance with 5 CFR 1320.10. Written comments and/or suggestions regarding the item(s) contained in this notice, especially regarding the estimated public burden and associated response time, should be directed to the Department of Homeland Security (DHS), and to the Office of Management and Budget (OMB), USCIS Desk Officer. Comments may be submitted to: USCIS, Chief, Regulatory Products Division, Clearance Office, 20 Massachusetts Avenue, Washington, DC 20529–2020. Comments may also be submitted to DHS via facsimile to 202–272–0997 or via e-mail at uscisfrcomment@dhs.gov, and to the OMB USCIS Desk Officer via facsimile at 202–395–5806 or via e-mail at oira_submission@omb.eop.gov. When submitting comments by e-mail please make sure to add OMB Control Number 1615–0048 in the subject box. Written comments and suggestions from the public and affected agencies should address one or more of the following four points: PO 00000 Frm 00064 Fmt 4703 Sfmt 4703 40385 (1) Evaluate whether the collection of information is necessary for the proper performance of the functions of the agency, including whether the information will have practical utility; (2) Evaluate the accuracy of the agency’s estimate of the burden of the collection of information, including the validity of the methodology and assumptions used; (3) Enhance the quality, utility, and clarity of the information to be collected; and (4) Minimize the burden of the collection of information on those who are to respond, including through the use of appropriate automated, electronic, mechanical, or other technological collection techniques, or other forms of information technology, e.g., permitting electronic submission of responses. Overview of This Information Collection (1) Type of Information Collection: Extension of an existing information collection. (2) Title of the Form/Collection: Request for Premium Processing Service. (3) Agency form number, if any, and the applicable component of the Department of Homeland Security sponsoring the collection: Form I–907. U.S. Citizenship and Immigration Services. (4) Affected public who will be asked or required to respond, as well as a brief abstract: Primary: Businesses. Through this form, USCIS provides employers with the opportunity to request expedite processing of certain employment-based requests. (5) An estimate of the total number of respondents and the amount of time estimated for an average respondent to respond: • Filing by Mail 96,000 responses at .50 hours (30 minutes) per response. • Electronically 4,000 responses at .333 hours (20 minutes) per response. (6) An estimate of the total public burden (in hours) associated with the collection: 49,332 annual burden hours. If you need a copy of the information collection instrument, please visit the Web site at: https://www.regulations.gov/ . We may also be contacted at: USCIS, Regulatory Products Division, 20 Massachusetts Avenue, NW., Washington, DC 20529–2020, telephone number 202–272–8377. E:\FR\FM\08JYN1.SGM 08JYN1

Agencies

[Federal Register Volume 76, Number 131 (Friday, July 8, 2011)]
[Notices]
[Pages 40384-40385]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-17214]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Center for Research Resources; Notice of Closed Meetings

    Pursuant to section 10(d) of the Federal Advisory Committee Act, as 
amended (5 U.S.C. App.), notice is hereby given of the following 
meetings.
    The meetings will be closed to the public in accordance with the 
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 
U.S.C., as amended. The grant applications and the discussions could 
disclose confidential trade secrets or commercial property such as 
patentable material, and personal information concerning individuals 
associated with the grant applications, the disclosure of which would 
constitute a clearly unwarranted invasion of personal privacy.

    Name of Committee: National Center for Research Resources 
Special Emphasis Panel, NCRR Animal Resource.
    Date: July 28, 2011.
    Time: 1 to 2 p.m.
    Agenda: To review and evaluate grant applications,
    Place: National Institutes of Health/NCRR/OR, Democracy 1, 6701 
Democracy Blvd., 1078, Bethesda, MD 20892.
    Contact Person: Lee Warren Slice, PhD, Scientific Review 
Officer, Office of Review, National Center for Research Resources, 
6701

[[Page 40385]]

Democracy Blvd., Room 1068, Bethesda, MD 20892, 301-435-0965, 
slicelw@mail.nih.gov.

(Catalogue of Federal Domestic Assistance Program Nos. 93.306, 
Comparative Medicine; 93.333, Clinical Research; 93.371, Biomedical 
Technology; 93.389, Research Infrastructure, 93.306, 93.333; 93.702, 
ARRA Related Construction Awards, National Institutes of Health, 
HHS)

    Dated: July 1, 2011.
Jennifer S. Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 2011-17214 Filed 7-7-11; 8:45 am]
BILLING CODE 4140-01-P
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