Findings of Research Misconduct, 23599-23600 [2011-10150]
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Federal Register / Vol. 76, No. 81 / Wednesday, April 27, 2011 / Notices
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[FR Doc. 2011–10160 Filed 4–26–11; 8:45 am]
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[FR Doc. 2011–10134 Filed 4–26–11; 8:45 am]
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[FR Doc. 2011–10133 Filed 4–26–11; 8:45 am]
BILLING CODE 6210–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Office of the Secretary
Findings of Research Misconduct
ACTION:
BILLING CODE 6210–01–P
Office of the Secretary, HHS.
Notice.
AGENCY:
Notice is hereby given that
the Office of Research Integrity (ORI)
has taken final action in the following
case:
Vipul Bhrigu, PhD, University of
Michigan Medical School: Based on the
findings of an investigation by the
University of Michigan Medical School
SUMMARY:
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23599
(UMMS) and additional analysis
conducted by the Office of Research
Integrity (ORI) during its oversight
review, ORI found that Vipul Bhrigu,
PhD, former postdoctoral fellow,
Department of Internal Medicine,
UMMS, engaged in research misconduct
in research funded by National Cancer
Institute (NCI), National Institutes of
Health (NIH), grant R01 CA098730–05.
Specifically, ORI found that the
Respondent knowingly and
intentionally tampered with research
materials related to five (5)
immunoprecipitation/Western blot
experiments and switched the labels on
four (4) cell culture dishes for cells used
in the same type of experiments to cause
false results to be reported in the
research record. ORI also found that the
Respondent tampered with laboratory
research materials by adding ethanol to
his colleague’s cell culture media, with
the deliberate intent to effectuate the
death of growing cells, which caused
false results to be reported in the
research record. ORI has concluded that
these acts seriously deviated from those
that are commonly accepted within the
scientific community for proposing,
conducting, and/or reporting research.
ORI found that the Respondent’s
intentional tampering of his colleague’s
laboratory research constitutes research
misconduct as defined by 42 CFR part
93. ORI determined that the Respondent
engaged in a pattern of dishonest
conduct through the commission of
multiple acts of data falsification. ORI
also determined that the subterfuge in
which he freely engaged for several
months constitutes an aggravating
factor. The Respondent attempted to
mislead the University of Michigan
(UM) police by initially denying
involvement in the tampering and
refusing to accept responsibility for this
misconduct. The Respondent eventually
made an admission only after the UM
police informed him that his actions in
the laboratory had been videotaped.
This dishonest conduct established the
Respondent’s lack of present
responsibility to be a steward of Federal
funds (2 CFR 376 et seq.; 42 CFR
93.408).
The following administrative actions
have been implemented for a period of
three (3) years, beginning on April 7,
2011:
(1) Dr. Bhrigu is debarred from
eligibility for any contracting or
subcontracting with any agency of the
United States Government and from
eligibility for, or involvement in,
nonprocurement programs of the United
States Government, referred to as
‘‘covered transactions,’’ pursuant to
HHS’ Implementation of OMB
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27APN1
23600
Federal Register / Vol. 76, No. 81 / Wednesday, April 27, 2011 / Notices
Guidelines to Agencies on
Governmentwide Debarment and
Suspension (2 CFR 376 et seq.); and
(2) Dr. Bhrigu is prohibited from
serving in any advisory capacity to the
U.S. Public Health Service (PHS),
including but not limited to service on
any PHS advisory committee, board,
and/or peer review committee, or as a
consultant.
FOR FURTHER INFORMATION CONTACT:
Director, Division of Investigative
Oversight, Office of Research Integrity,
1101 Wootton Parkway, Suite 750,
Rockville, MD 20852, (240) 453–8800.
John Dahlberg,
Director, Division of Investigative Oversight,
Office of Research Integrity.
[FR Doc. 2011–10150 Filed 4–26–11; 8:45 am]
BILLING CODE 4150–31–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Office of the Secretary
Findings of Research Misconduct
Office of the Secretary, HHS.
ACTION: Notice.
AGENCY:
Notice is hereby given that
the Office of Research Integrity (ORI)
has taken final action in the following
case:
Junghee J. Shin, PhD, New York
Medical College: Based on the report of
an investigation conducted by New
York Medical College (NYMC) and
additional analysis by the Office of
Research Integrity (ORI) in its oversight
review, the U.S. Public Health Service
(PHS) found that Junghee J. Shin, PhD,
former graduate student, NYMC,
engaged in research misconduct in
research supported by National Institute
of Allergy and Infectious Diseases
(NIAID), National Institutes of Health
(NIH), grants R01 AI048856 and R01
AI043063.
PHS found that the Respondent
engaged in research misconduct by
falsifying data in Figure 4 of a
manuscript submitted to the journal
Infection and Immunity (Shin, J.J.,
Godfrey, H.P., & Cabello, F.C.
‘‘Expression and localization of BmpC in
Borrelia burgdorferi after growth under
various environmental conditions.’’
Submitted to Infection and Immunity;
hereafter referred to as the
‘‘manuscript’’) and Figure 5 of a paper
published in Infection and Immunity
(Shin, J.J. Bryksin, A.V., Godfrey, H.P.,
& Cabello, F.C. ‘‘Localization of BmpA
on the exposed outer membrane of
Borrelia burgdorferi by monospecific
anti-recombinant BmpA rabbit
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SUMMARY:
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antibodies.’’ Infection and Immunity
72(4):2280–2287, April 2004; hereafter
referred to as the ‘‘paper.’’ Retracted in:
Infection and Immunity 76(10):4792,
October 2008). Specifically, NYMC and
ORI found that:
• Dr. Shin falsified microscopic
immunofluorescence blank images in
Figure 4 of the manuscript (top row, 1st,
2nd, 4th, and 5th panels, and bottom
row, 1st panel) and Figure 5 of the paper
(top row, 1st and 5th panels, lower 1st
panel) by using one blank image from an
unknown experiment to falsely
represent the preimmunization control
conditions (intact cells and methanol
fixation) as well as the negative staining
of anti-BmpC and anti-FlaB in Figure 4
and anti-FlaB in Figure 5 on intact cells.
• Dr. Shin falsified at least one of two
images in Figure 4 of the manuscript
and Figure 5 of the paper by using
different portions of a green-red pair of
microscopic immunofluorescence
images (1230036.tif and 1230037.tif)
because unfixed cells staining positive
for BmpA in the top row, 4th panel, of
Figure 5 were the same unfixed cells
purportedly positive for OspA in the top
row, 3rd panel, of Figure 4.
• Dr. Shin falsified at least one of two
images in Figure 4 of the manuscript
and Figure 5 of the paper by using
different photo cropping from a single
microscopic immunofluorescence image
(1230039.tif) to represent fixed cells
positive for BmpA and labeled with
anti-FlaB in the lower row, 5th panel, of
Figure 5 and to also represent fixed cells
positive for BmpC and stained with
anti-FlaB in the lower row, 5th panel, of
Figure 4.
Dr. Shin has entered into a Voluntary
Settlement Agreement in which she has
voluntarily agreed, for a period of three
(3) years, beginning on April 5, 2011:
(1) That any institution that submits
an application for PHS support for a
research project on which the
Respondent’s participation is proposed
or that uses her in any capacity on PHSsupported research, or that submits a
report of PHS-funded research in which
she is involved, must concurrently
submit a plan for supervision of her
duties to ORI for approval; the
supervisory plan must be designed to
ensure the scientific integrity of her
research contribution; Respondent
agrees that she will not participate in
any PHS-supported research until such
a supervision plan is submitted to ORI;
and
(2) to exclude herself voluntarily from
service in any advisory capacity to PHS,
including but not limited to service on
any PHS advisory committee, board,
and/or peer review committee, or as a
consultant.
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FOR FURTHER INFORMATION CONTACT:
Director, Division of Investigative
Oversight, Office of Research Integrity,
1101 Wootton Parkway, Suite 750,
Rockville, MD 20852, (240) 453–8800.
John Dahlberg,
Director, Division of Investigative Oversight,
Office of Research Integrity.
[FR Doc. 2011–10157 Filed 4–26–11; 8:45 am]
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SUMMARY:
E:\FR\FM\27APN1.SGM
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Agencies
[Federal Register Volume 76, Number 81 (Wednesday, April 27, 2011)]
[Notices]
[Pages 23599-23600]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-10150]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Office of the Secretary
Findings of Research Misconduct
AGENCY: Office of the Secretary, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: Notice is hereby given that the Office of Research Integrity
(ORI) has taken final action in the following case:
Vipul Bhrigu, PhD, University of Michigan Medical School: Based on
the findings of an investigation by the University of Michigan Medical
School (UMMS) and additional analysis conducted by the Office of
Research Integrity (ORI) during its oversight review, ORI found that
Vipul Bhrigu, PhD, former postdoctoral fellow, Department of Internal
Medicine, UMMS, engaged in research misconduct in research funded by
National Cancer Institute (NCI), National Institutes of Health (NIH),
grant R01 CA098730-05.
Specifically, ORI found that the Respondent knowingly and
intentionally tampered with research materials related to five (5)
immunoprecipitation/Western blot experiments and switched the labels on
four (4) cell culture dishes for cells used in the same type of
experiments to cause false results to be reported in the research
record. ORI also found that the Respondent tampered with laboratory
research materials by adding ethanol to his colleague's cell culture
media, with the deliberate intent to effectuate the death of growing
cells, which caused false results to be reported in the research
record. ORI has concluded that these acts seriously deviated from those
that are commonly accepted within the scientific community for
proposing, conducting, and/or reporting research.
ORI found that the Respondent's intentional tampering of his
colleague's laboratory research constitutes research misconduct as
defined by 42 CFR part 93. ORI determined that the Respondent engaged
in a pattern of dishonest conduct through the commission of multiple
acts of data falsification. ORI also determined that the subterfuge in
which he freely engaged for several months constitutes an aggravating
factor. The Respondent attempted to mislead the University of Michigan
(UM) police by initially denying involvement in the tampering and
refusing to accept responsibility for this misconduct. The Respondent
eventually made an admission only after the UM police informed him that
his actions in the laboratory had been videotaped. This dishonest
conduct established the Respondent's lack of present responsibility to
be a steward of Federal funds (2 CFR 376 et seq.; 42 CFR 93.408).
The following administrative actions have been implemented for a
period of three (3) years, beginning on April 7, 2011:
(1) Dr. Bhrigu is debarred from eligibility for any contracting or
subcontracting with any agency of the United States Government and from
eligibility for, or involvement in, nonprocurement programs of the
United States Government, referred to as ``covered transactions,''
pursuant to HHS' Implementation of OMB
[[Page 23600]]
Guidelines to Agencies on Governmentwide Debarment and Suspension (2
CFR 376 et seq.); and
(2) Dr. Bhrigu is prohibited from serving in any advisory capacity
to the U.S. Public Health Service (PHS), including but not limited to
service on any PHS advisory committee, board, and/or peer review
committee, or as a consultant.
FOR FURTHER INFORMATION CONTACT: Director, Division of Investigative
Oversight, Office of Research Integrity, 1101 Wootton Parkway, Suite
750, Rockville, MD 20852, (240) 453-8800.
John Dahlberg,
Director, Division of Investigative Oversight, Office of Research
Integrity.
[FR Doc. 2011-10150 Filed 4-26-11; 8:45 am]
BILLING CODE 4150-31-P