Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy Commissioner, International Programs, Food and Drug Administration and Mr. Martin Heraghty, Assistant Secretary General, Department of Agriculture, Fisheries and Food of Ireland Concerning Certification Requirements for Caseins, Caseinates, and Mixtures Thereof Exported From Ireland to the United States, 14407-14413 [2011-6079]
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Dated: February 25, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
[FR Doc. 2011–6055 Filed 3–15–11; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2011–N–0109]
Exchange of Letters Between Dr.
Murray M. Lumpkin, Deputy
Commissioner, International
Programs, Food and Drug
Administration and Mr. Martin
Heraghty, Assistant Secretary General,
Department of Agriculture, Fisheries
and Food of Ireland Concerning
Certification Requirements for
Caseins, Caseinates, and Mixtures
Thereof Exported From Ireland to the
United States
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is providing
notice of exchange of letters between Dr.
Murray M. Lumpkin, Deputy
Commissioner, International and
Special Programs, FDA and Mr. Martin
Heraghty, Assistant Secretary General,
Department of Agriculture, Fisheries
and Food (DAFF), concerning
certification requirements for caseins,
SUMMARY:
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14407
caseinates, and mixtures thereof
exported from Ireland to the United
States.
The mutual goals of FDA and DAFF
in establishing certification
requirements for caseins, caseinates,
and mixtures thereof exported from
Ireland to the United States are to assure
that contaminated products will not be
imported into the United States and to
minimize the need for extensive FDA
audit sampling of these products from
Ireland. DAFF and FDA have a history
of cooperation on this issue and it is,
therefore, desirable that the two
Agencies continue to cooperate to
maintain and improve consumer
protection.
The agreement became effective
November 10, 2010.
FOR FURTHER INFORMATION CONTACT:
David P. Kelly, Office of International
Programs, Food and Drug
Administration, 10903 New Hampshire
Ave., Bldg. 31, rm. 3404, Silver Spring,
MD 20993–0002, 301–796–8373, Fax:
301–595–7941.
SUPPLEMENTARY INFORMATION: In
accordance with 21 CFR 20.108(c),
which states that all written agreements
and understandings between FDA and
others shall be published in the Federal
Register, the Agency is publishing
notice of this agreement.
DATES:
Dated: March 10, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
BILLING CODE 4160–01–P
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BILLING CODE 4160–01–C
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2011–N–0002]
Risk Mitigation Strategies To Address
Potential Procoagulant Activity in
Immune Globulin Intravenous
Products; Public Workshop
AGENCY:
Food and Drug Administration,
HHS.
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ACTION:
Notice of public workshop.
The Food and Drug Administration
(FDA), in cooperation with the National
Heart, Lung, and Blood Institute, and
the Plasma Protein Therapeutics
Association, are jointly cosponsoring a
public workshop on risk mitigation
strategies to address procoagulant
activity that may be present in some
Immune Globulin Intravenous (IGIV)
products. The purposes of the public
workshop are to identify the most likely
causes of IGIV-associated thrombotic
events, to determine which
procoagulant proteins may be causative,
and to identify relevant, feasible tests
that could be used to assess levels and/
or activity of these proteins in IGIV
products. The public workshop will
feature presentations by national and
international experts from government,
academic institutions, and industry.
Dates and Time: The public workshop
will be held on May 17, 2011, from 8:30
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a.m. to 5 p.m. and May 18, 2011, from
8 a.m. to 11:30 a.m.
Location: The public workshop will
be held at the Universities at Shady
Grove Conference Center, Building II,
Multipurpose Room, 9630 Gudelsky Dr.,
Rockville, MD 20850. Please visit
https://www.shadygrove.umd.edu/about/
visit for directions, visitor parking, and
public transportation information.
Contact Person: Rhonda Dawson,
Center for Biologics Evaluation and
Research (HFM–302), Food and Drug
Administration, 1401 Rockville Pike,
suite 200N, Rockville, MD 20852–1448,
301–827–6129, FAX: 301–827–2843, email: rhonda.dawson@fda.hhs.gov.
Registration: Mail or fax your
registration information (including
name, title, firm name, address,
telephone and fax numbers) to the
contact person by April 26, 2011. There
is no registration fee for the public
workshop. Early registration is
recommended because seating is
limited. Registration on the day of the
public workshop will be provided on a
space available basis beginning at 7:30
a.m.
If you need special accommodations
due to a disability, please contact
Rhonda Dawson at least 7 days in
advance of the workshop.
SUPPLEMENTARY INFORMATION: The
following topics will be discussed at the
public workshop: (1) Epidemiology of
thrombotic events in IGIV recipients; (2)
pathophysiology of arterial and venous
thrombosis in this context; (3) research
to identify specific procoagulant
proteins that can co-purify with IGIV;
(4) partitioning of coagulation factors
during IGIV purification; (5) the role of
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activated Coagulation Factor XIa in
IGIV-associated thrombosis; (6) test
methods for screening IGIV products; (7)
ancillary animal models; and (8)
standards development for thrombin
generation tests. On the first day of the
public workshop, the epidemiology and
potential causes of historically observed
IGIV-associated thrombotic adverse
events, as well as biochemical
identification of procoagulant proteins
that co-purify with IGIV will be
discussed. In addition, methods and
relevance of both broad and specific
tests to screen IGIV products for
procoagulant activity will be addressed,
and limitations in test methodologies
and validation needs will be identified.
On the second day of the public
workshop, preliminary results of IGIV
product testing for procoagulant activity
will be presented and discussed,
followed by a summary of the meeting.
Transcripts: Transcripts of the public
workshop may be requested in writing
from the Freedom of Information Office
(HFI–35), Food and Drug
Administration, 5600 Fishers Lane, rm.
6–30, Rockville, MD 20857,
approximately 15 working days after the
public workshop at a cost of 10 cents
per page. A transcript of the public
workshop will be available on the
Internet at https://www.fda.gov/
BiologicsBloodVaccines/NewsEvents/
WorkshopsMeetingsConferences/
TranscriptsMinutes/default.htm.
Dated: March 10, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
[FR Doc. 2011–6084 Filed 3–15–11; 8:45 am]
BILLING CODE 4160–01–P
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[FR Doc. 2011–6079 Filed 3–15–11; 8:45 am]
14413
Agencies
[Federal Register Volume 76, Number 51 (Wednesday, March 16, 2011)]
[Notices]
[Pages 14407-14413]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-6079]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2011-N-0109]
Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy
Commissioner, International Programs, Food and Drug Administration and
Mr. Martin Heraghty, Assistant Secretary General, Department of
Agriculture, Fisheries and Food of Ireland Concerning Certification
Requirements for Caseins, Caseinates, and Mixtures Thereof Exported
From Ireland to the United States
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is providing notice of
exchange of letters between Dr. Murray M. Lumpkin, Deputy Commissioner,
International and Special Programs, FDA and Mr. Martin Heraghty,
Assistant Secretary General, Department of Agriculture, Fisheries and
Food (DAFF), concerning certification requirements for caseins,
caseinates, and mixtures thereof exported from Ireland to the United
States.
The mutual goals of FDA and DAFF in establishing certification
requirements for caseins, caseinates, and mixtures thereof exported
from Ireland to the United States are to assure that contaminated
products will not be imported into the United States and to minimize
the need for extensive FDA audit sampling of these products from
Ireland. DAFF and FDA have a history of cooperation on this issue and
it is, therefore, desirable that the two Agencies continue to cooperate
to maintain and improve consumer protection.
DATES: The agreement became effective November 10, 2010.
FOR FURTHER INFORMATION CONTACT: David P. Kelly, Office of
International Programs, Food and Drug Administration, 10903 New
Hampshire Ave., Bldg. 31, rm. 3404, Silver Spring, MD 20993-0002, 301-
796-8373, Fax: 301-595-7941.
SUPPLEMENTARY INFORMATION: In accordance with 21 CFR 20.108(c), which
states that all written agreements and understandings between FDA and
others shall be published in the Federal Register, the Agency is
publishing notice of this agreement.
Dated: March 10, 2011.
Leslie Kux,
Acting Assistant Commissioner for Policy.
BILLING CODE 4160-01-P
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[FR Doc. 2011-6079 Filed 3-15-11; 8:45 am]
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