National Institute of Environmental Health Sciences (NIEHS); Request for Information (NOT-ES-11-006): Interagency Breast Cancer and Environmental Research Coordinating Committee, 5185-5186 [2011-1871]

Download as PDF Federal Register / Vol. 76, No. 19 / Friday, January 28, 2011 / Notices Dated: January 24, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. your responses to ibcercc@niehs.nih.gov; or 2. Mail or fax your responses in a letter to the attention of the contact person listed in the FOR FURTHER INFORMATION CONTACT section of this document. [FR Doc. 2011–1873 Filed 1–27–11; 8:45 am] BILLING CODE 4140–01–P FOR FURTHER INFORMATION CONTACT: DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Environmental Health Sciences (NIEHS); Request for Information (NOT–ES–11–006): Interagency Breast Cancer and Environmental Research Coordinating Committee Jennifer B. Collins, Division of Extramural Research and Training, NIEHS, P.O. Box 12233, MD K3–12, RTP, NC 27709; Telephone: 919–541– 0117, FAX: 919–541–2860, E-mail: collins6@niehs.nih.gov. SUPPLEMENTARY INFORMATION: Background The Committee’s primary mission is to facilitate the efficient and effective exchange of information on breast cancer research activities among the member agencies, and to advise the NIH and other Federal agencies in the solicitation of proposals for SUMMARY: The Interagency Breast Cancer collaborative, multidisciplinary and Environmental Research research, including proposals to further Coordinating Committee is a evaluate environmental and genomic congressionally mandated body factors that may be related to the established by the National Institute of etiology of breast cancer. The Environmental Health Sciences Committee serves as a forum and assists (NIEHS), in collaboration with the in increasing public understanding of National Cancer Institute (NCI). This the member agencies’ activities, Committee is comprised of 19 voting programs, policies, and research, and in members, including representatives of bringing important matters of interest Federal agencies; non-federal scientists, forward for discussion. physicians, and other health Definition of Environment: For the professionals from clinical, basic, and purpose of this RFI, ‘‘environment’’ is public health sciences; and advocates broadly defined as any factors that are for individuals with breast cancer. non-genetic in nature. This can include The IBCERCC is charged with reviewing all research efforts within the environmental chemicals, radiation, biological agents, pharmaceuticals, U.S. Department of Health and Human nutritional factors, and psychosocial Services (HHS) concerning the and behavioral stressors. environmental and genomic factors Definition of Systems Biology: For the related to the etiology of breast cancer, purpose of this RFI, ‘‘systems biology’’ and developing a comprehensive refers to a holistic approach to the study summary of advances and of breast cancer etiology with the recommendations regarding research objective of simultaneously monitoring gaps and needs for the Secretary of all biological processes and HHS. environmental exposures operating as This Request for Information (RFI) is an integrated system. directed toward addressing questions relevant to the Committee’s mandate. Information Requested The RFI was announced in the NIH Input is invited on the items listed Guide on January 13, 2011, and is available at https://grants.nih.gov/grants/ below and will be used as a resource by guide/notice-files/NOT-ES-11-006.html. the IBCERCC members during the development of the comprehensive DATES: A response is requested by summary of advances and February 16, 2011. Responses received recommendations regarding research after February 16, 2011 will be gaps and needs for the Secretary of considered to the extent possible. HHS. Comment on each item is Responses: Please send responses to the IBCERCC (ibcercc@niehs.nih.gov) by optional. (1) How susceptibility to the effects of February 16, 2011. The following are environmental exposures in sub-groups acceptable ways to submit your of the population (resulting from factors responses: such as genetic or epigenetic variability, 1. Copy and paste the questions into the body of an e-mail message and send or timing of exposure during National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH). ACTION: Request for information. WReier-Aviles on DSKGBLS3C1PROD with NOTICES AGENCY: VerDate Mar<15>2010 15:05 Jan 27, 2011 Jkt 223001 PO 00000 Frm 00056 Fmt 4703 Sfmt 4703 5185 development or other stages) impacts breast cancer risk. (2) Differences in the type and extent of environmental exposures which help explain the differential distribution of breast cancer subtypes in the U.S. population. (3) How windows of susceptibility during the life-course can be integrated into a complex systems biology approach to better understand the role of the environment and breast cancer. (4) How additional insight into normal mammary gland development through research using cell lines and animal models can enhance our understanding of environmental exposures and mammary carcinogenesis. (5) The technologies and analytic capacity needed to accurately measure environmental exposures (including biological dose) and to develop markers of early damage relevant to breast cancer risk. (6) The translation of research findings to the public about the environment and breast cancer risk considering the timing, and the strength of evidence, and the roles of community and advocacy groups. (7) Engagement of advocacy organizations to ensure that environmental exposures of greatest interest and concern are studied and the role of media, data access, and publication access in this process. (8) Approaches and effective models for coordination and collaboration among research agencies of the Federal Government to identify emerging opportunities in and programs to study environmental causes of breast cancer, such as in peer review, collaborative program development, and models for supporting cross-agency opportunities. This Request for Information (RFI) is for information and planning purposes only and should not be construed as a solicitation or as an obligation on the part of the Federal Government, the National Institutes of Health (NIH), National Institute of Environmental Health Sciences (NIEHS) and or the National Cancer Institute (NCI). The NIH does not intend to award a grant or contract to pay for the preparation of any information submitted or for the NIH’s use of such information. Respondents will not be notified of the NIH evaluation of the information received. No basis for claims against the NIH shall arise as a result of a response to this request for information or the NIH’s use of such information as either part of our evaluation process or in developing specifications for any subsequent announcement. Responses E:\FR\FM\28JAN1.SGM 28JAN1 5186 Federal Register / Vol. 76, No. 19 / Friday, January 28, 2011 / Notices will be held confidential. Proprietary information should not be sent. Dated: January 19, 2011. Linda S. Birnbaum, Director, National Institute of Environmental Health Sciences and National Toxicology Program. [FR Doc. 2011–1871 Filed 1–27–11; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS–2010–0084] National Protection and Programs Directorate; Agency Information Collection Activities; Office of Infrastructure Protection; Infrastructure Protection Stakeholder Input Project—Generic Clearance National Protection and Programs Directorate, DHS. ACTION: 30-day notice and request for comments; New Information Collection Request: 1670–NEW. AGENCY: The Department of Homeland Security (DHS), National Protection and Programs Directorate (NPPD), Office of Infrastructure Protection (IP), will submit the following information collection request (ICR) to the Office of Management and Budget (OMB) for review and clearance in accordance with the Paperwork Reduction Act of 1995 (Pub. L. 104–13, 44 U.S.C. Chapter 35). IP is soliciting comments concerning this New Information Collection Request, Infrastructure Protection Stakeholder Input Project— Generic Clearance. DHS previously published this information collection request (ICR) in the Federal Register on November 4, 2010, at 75 FR 67989, for a 60-day public comment period. No comments were received by DHS. The purpose of this notice is to allow additional 30 days for public comments. DATES: Comments are encouraged and will be accepted until February 28, 2011. This process is conducted in accordance with 5 CFR 1320.10. ADDRESSES: Interested persons are invited to submit written comments on the proposed information collection to the Office of Information and Regulatory Affairs, OMB. Comments should be addressed to the OMB Desk Officer, Department of Homeland Security, Office of Civil Rights and Civil Liberties. Comments must be identified by DHS– 2010–0084 and may be submitted by one of the following methods: • Federal eRulemaking Portal: https:// www.regulations.gov . WReier-Aviles on DSKGBLS3C1PROD with NOTICES SUMMARY: VerDate Mar<15>2010 15:05 Jan 27, 2011 Jkt 223001 • E-mail: oira_submission@omb.eop.gov. Include the docket number in the subject line of the message. • Fax: (202) 395–5806. Instructions: All submissions received must include the words ‘‘Department of Homeland Security’’ and the docket number for this action. Comments received will be posted without alteration at https://www.regulations.gov, including any personal information provided. OMB is particularly interested in comments that: 1. Evaluate whether the proposed collection of information is necessary for the proper performance of the functions of the agency, including whether the information will have practical utility; 2. Evaluate the accuracy of the agency’s estimate of the burden of the proposed collection of information, including the validity of the methodology and assumptions used; 3. Enhance the quality, utility, and clarity of the information to be collected; and 4. Minimize the burden of the collection of information on those who are to respond, including through the use of appropriate automated, electronic, mechanical, or other technological collection techniques or other forms of information technology, e.g., permitting electronic submissions of responses. FOR FURTHER INFORMATION CONTACT: If additional information is required, contact DHS/NPPD/IP, Michael Beland, (703) 235–3696, Michael.Beland@hq.dhs.gov. The Homeland Security Act of 2002 and Homeland Security Presidential Directive 7 (HSPD–7) call for DHS to coordinate the overall effort to enhance the protection of the Nation’s critical infrastructure and key resources. Specifically, HSPD–7 states that DHS ‘‘shall establish appropriate systems, mechanisms, and procedures to share homeland security information relevant to threats and vulnerabilities in national critical infrastructure and key resources with other Federal departments and agencies, State and local governments, and the private sector in a timely manner.’’ DHS designated IP to lead these efforts. Given that the vast majority of the Nation’s critical infrastructure and key resources in most sectors are privately owned or controlled, IP’s success in achieving the homeland security mission for critical infrastructure protection and resilience is dependent SUPPLEMENTARY INFORMATION: PO 00000 Frm 00057 Fmt 4703 Sfmt 4703 upon how well critical infrastructure owners and operators and members of the general public understand the key concepts, are aware of their contribution to achieve a shared national goal, participate in public-private partnerships, and are motivated to take action. However, IP has never conducted a comprehensive feedback assessment with the full range of its stakeholders to identify, measure, and improve the effectiveness of its efforts. IP desires to collect information from its stakeholders in order to: • Provide a baseline for the effectiveness of efforts to improve the security of the nation’s infrastructure; • Assist in validating and achieving IP’s strategic and mission area objectives; • Obtain a better understanding of the evolving infrastructure protection and resiliency requirements of IP’s stakeholders; • Increase the visibility and awareness of the critical infrastructure protection and resilience mission; • Initiate the coordination and uniformity of outreach efforts by IP, sector-specific agencies, and other partners engaged in the infrastructure protection mission; and • Collect feedback regarding event, threat or service-specific activities in a timely fashion. Analysis Agency: Department of Homeland Security, National Protection and Programs Directorate. Title: Infrastructure Protection Stakeholder Input Project—Generic Clearance. OMB Number: 1670–NEW. IP Stakeholder Input Project—Surveys Frequency: On occasion. Affected Public: Private sector and non-Federal infrastructure protection community. Number of Respondents: 5,980. Estimated Time per Respondent: 40 minutes. Total Burden Hours: 3,056 annual burden hours. Total Burden Cost (capital/startup): $0. Total Burden Cost (operating/ maintaining): $0. IP Stakeholder Input Project—Focus Groups Frequency: On occasion. Affected Public: Private sector and non-Federal infrastructure protection community. Number of Respondents: 260. Estimated Time per Respondent: 2 hours. E:\FR\FM\28JAN1.SGM 28JAN1

Agencies

[Federal Register Volume 76, Number 19 (Friday, January 28, 2011)]
[Notices]
[Pages 5185-5186]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-1871]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Institute of Environmental Health Sciences (NIEHS); 
Request for Information (NOT-ES-11-006): Interagency Breast Cancer and 
Environmental Research Coordinating Committee

AGENCY: National Institute of Environmental Health Sciences (NIEHS), 
National Institutes of Health (NIH).

ACTION: Request for information.

-----------------------------------------------------------------------

SUMMARY: The Interagency Breast Cancer and Environmental Research 
Coordinating Committee is a congressionally mandated body established 
by the National Institute of Environmental Health Sciences (NIEHS), in 
collaboration with the National Cancer Institute (NCI). This Committee 
is comprised of 19 voting members, including representatives of Federal 
agencies; non-federal scientists, physicians, and other health 
professionals from clinical, basic, and public health sciences; and 
advocates for individuals with breast cancer.
    The IBCERCC is charged with reviewing all research efforts within 
the U.S. Department of Health and Human Services (HHS) concerning the 
environmental and genomic factors related to the etiology of breast 
cancer, and developing a comprehensive summary of advances and 
recommendations regarding research gaps and needs for the Secretary of 
HHS.
    This Request for Information (RFI) is directed toward addressing 
questions relevant to the Committee's mandate. The RFI was announced in 
the NIH Guide on January 13, 2011, and is available at https://grants.nih.gov/grants/guide/notice-files/NOT-ES-11-006.html.

DATES: A response is requested by February 16, 2011. Responses received 
after February 16, 2011 will be considered to the extent possible.
    Responses: Please send responses to the IBCERCC 
(ibcercc@niehs.nih.gov) by February 16, 2011. The following are 
acceptable ways to submit your responses:
    1. Copy and paste the questions into the body of an e-mail message 
and send your responses to ibcercc@niehs.nih.gov; or
    2. Mail or fax your responses in a letter to the attention of the 
contact person listed in the FOR FURTHER INFORMATION CONTACT section of 
this document.

FOR FURTHER INFORMATION CONTACT: Jennifer B. Collins, Division of 
Extramural Research and Training, NIEHS, P.O. Box 12233, MD K3-12, RTP, 
NC 27709; Telephone: 919-541-0117, FAX: 919-541-2860, E-mail: 
collins6@niehs.nih.gov.

SUPPLEMENTARY INFORMATION:

Background

    The Committee's primary mission is to facilitate the efficient and 
effective exchange of information on breast cancer research activities 
among the member agencies, and to advise the NIH and other Federal 
agencies in the solicitation of proposals for collaborative, 
multidisciplinary research, including proposals to further evaluate 
environmental and genomic factors that may be related to the etiology 
of breast cancer. The Committee serves as a forum and assists in 
increasing public understanding of the member agencies' activities, 
programs, policies, and research, and in bringing important matters of 
interest forward for discussion.
    Definition of Environment: For the purpose of this RFI, 
``environment'' is broadly defined as any factors that are non-genetic 
in nature. This can include environmental chemicals, radiation, 
biological agents, pharmaceuticals, nutritional factors, and 
psychosocial and behavioral stressors.
    Definition of Systems Biology: For the purpose of this RFI, 
``systems biology'' refers to a holistic approach to the study of 
breast cancer etiology with the objective of simultaneously monitoring 
all biological processes and environmental exposures operating as an 
integrated system.

Information Requested

    Input is invited on the items listed below and will be used as a 
resource by the IBCERCC members during the development of the 
comprehensive summary of advances and recommendations regarding 
research gaps and needs for the Secretary of HHS. Comment on each item 
is optional.
    (1) How susceptibility to the effects of environmental exposures in 
sub-groups of the population (resulting from factors such as genetic or 
epigenetic variability, or timing of exposure during development or 
other stages) impacts breast cancer risk.
    (2) Differences in the type and extent of environmental exposures 
which help explain the differential distribution of breast cancer 
subtypes in the U.S. population.
    (3) How windows of susceptibility during the life-course can be 
integrated into a complex systems biology approach to better understand 
the role of the environment and breast cancer.
    (4) How additional insight into normal mammary gland development 
through research using cell lines and animal models can enhance our 
understanding of environmental exposures and mammary carcinogenesis.
    (5) The technologies and analytic capacity needed to accurately 
measure environmental exposures (including biological dose) and to 
develop markers of early damage relevant to breast cancer risk.
    (6) The translation of research findings to the public about the 
environment and breast cancer risk considering the timing, and the 
strength of evidence, and the roles of community and advocacy groups.
    (7) Engagement of advocacy organizations to ensure that 
environmental exposures of greatest interest and concern are studied 
and the role of media, data access, and publication access in this 
process.
    (8) Approaches and effective models for coordination and 
collaboration among research agencies of the Federal Government to 
identify emerging opportunities in and programs to study environmental 
causes of breast cancer, such as in peer review, collaborative program 
development, and models for supporting cross-agency opportunities.
    This Request for Information (RFI) is for information and planning 
purposes only and should not be construed as a solicitation or as an 
obligation on the part of the Federal Government, the National 
Institutes of Health (NIH), National Institute of Environmental Health 
Sciences (NIEHS) and or the National Cancer Institute (NCI). The NIH 
does not intend to award a grant or contract to pay for the preparation 
of any information submitted or for the NIH's use of such information. 
Respondents will not be notified of the NIH evaluation of the 
information received. No basis for claims against the NIH shall arise 
as a result of a response to this request for information or the NIH's 
use of such information as either part of our evaluation process or in 
developing specifications for any subsequent announcement. Responses

[[Page 5186]]

will be held confidential. Proprietary information should not be sent.

    Dated: January 19, 2011.
Linda S. Birnbaum,
Director, National Institute of Environmental Health Sciences and 
National Toxicology Program.
[FR Doc. 2011-1871 Filed 1-27-11; 8:45 am]
BILLING CODE 4140-01-P
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