2010 – Federal Register Recent Federal Regulation Documents

Results 9,401 - 9,450 of 32,765
Implementation of the Intelligent Mail Package Barcode
Document Number: 2010-23313
Type: Proposed Rule
Date: 2010-09-17
Agency: Postal Service, Agencies and Commissions
The Postal Service is proposing to incorporate standards into Mailing Standards of the United States Postal Service, Domestic Mail Manual (DMM[supreg]) for the optional use of Intelligent Mail[supreg] package barcodes (IMpb), no later than January of 2011; and expects to require the mandatory use of IMpb on all domestic packages beginning in January 2012.
Petition of the National Futures Association, Pursuant to Rule 13.2, to the U.S. Commodity Futures Trading Commission To Amend of the Rule 4.5
Document Number: 2010-23310
Type: Notice
Date: 2010-09-17
Agency: Commodity Futures Trading Commission, Agencies and Commissions
The National Futures Association (``NFA'') has petitioned the Commodity Futures Trading Commission (``Commission'' or ``CFTC'') to amend a rule that excludes certain otherwise regulated persons from the definition of the term ``commodity pool operator'' (``CPO'') with respect to certain qualifying entities. The rule presently requires any person desiring to claim the exclusion to file a notice of eligibility with NFA, which must identify the qualifying entity to be operated pursuant to the exclusion. NFA requests the Commission amend its rule to limit the scope of the exclusion for registered investment companies (``RICs''). Specifically, NFA has requested that any RIC include in its notice of eligibility a representation that the RIC's qualifying entity (1) Will use commodity futures or commodity options contracts solely for bona fide hedging purposes, (2) will not have the initial margin and premiums required to establish any commodity futures or commodity options not used for bona fide hedging purposes exceeding five percent (5%) of the liquidation value of the qualifying entity's portfolio, and (3) will not be marketed to the public as a commodity pool or as a vehicle for investment in commodity futures or commodity options. The Commission seeks comment on NFA's petition and any related questions. Copies of the petition are available for inspection at the Office of the Secretariat, by mail at the address listed below, by telephoning (202) 418-5100, or on the Commission's Web site (https:// www.cftc.gov).
Notice Inviting Publishers To Submit Tests for a Determination of Suitability for Use in the National Reporting System for Adult Education
Document Number: 2010-23309
Type: Notice
Date: 2010-09-17
Agency: Department of Education
The Department of Education (Department) announces the date by which test publishers must submit tests to the Secretary for review and approval for use in the National Reporting System for Adult Education (NRS).
Global Markets Advisory Committee
Document Number: 2010-23307
Type: Notice
Date: 2010-09-17
Agency: Commodity Futures Trading Commission, Agencies and Commissions
The Global Markets Advisory Committee will hold a public meeting on October 5, 2010, from 1 p.m. to 5 p.m., at the CFTC's Washington, DC headquarters.
Meeting of the Presidential Advisory Council on HIV/AIDS
Document Number: 2010-23306
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services
As stipulated by the Federal Advisory Committee Act, the U.S. Department of Health and Human Services (DHHS) is hereby giving notice that the Presidential Advisory Council on HIV/AIDS (PACHA) will hold a meeting. The meeting will be open to the public.
153rd Meeting of the Advisory Council on Employee Welfare and Pension Benefit Plans; Notice of Meeting
Document Number: 2010-23304
Type: Notice
Date: 2010-09-17
Agency: Employee Benefits Security Administration, Department of Labor
Proposed Collection; Comment Request
Document Number: 2010-23301
Type: Notice
Date: 2010-09-17
Agency: Community Development Financial Institutions Fund, Department of Treasury, Department of the Treasury
The U.S. Department of the Treasury, as part of its continuing effort to reduce paperwork and respondent burden, invites the general public and other Federal agencies to take this opportunity to comment on proposed information collections, as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently, the Community Development Financial Institutions (CDFI) Fund, Department of the Treasury, is soliciting comments concerning reporting and record retention requirements for the Capital Magnet Fund (CMF).
Expansion of Foreign-Trade Zone 157, Casper, WY
Document Number: 2010-23300
Type: Notice
Date: 2010-09-17
Agency: Department of Commerce, Foreign-Trade Zones Board
Approval and Promulgation of State Implementation Plans; State of Colorado; Interstate Transport of Pollution Revisions for the 1997 8-hour Ozone NAAQS: “Interference With Maintenance” Requirement
Document Number: 2010-23294
Type: Proposed Rule
Date: 2010-09-17
Agency: Environmental Protection Agency
EPA is proposing to approve the ``State of Colorado Implementation Plan to Meet the Requirements of Clean Air Act section 110(a)(2)(D)(i)(I)Interstate Transport Regarding the 1997 8-Hour Ozone Standard'' addressing the ``interference with maintenance'' requirement of section 110(a)(2)(D)(i)(I). On June 18, 2009 the State of Colorado submitted an interstate transport State Implementation Plan (SIP) addressing the interstate transport requirements under section 110(a)(2)(D)(i) of the Clean Air Act (CAA). In this action, EPA is proposing to approve the Colorado Interstate Transport SIP provisions that address the section 110(a)(2)(D)(i)(I) requirement prohibiting a state's emissions from interfering with maintenance of the 1997 8-hour ozone National Ambient Air Quality Standards (NAAQS) by any other state. This action is being taken under section 110 of the CAA.
Proposed Collection of Information; Comment Request
Document Number: 2010-23293
Type: Notice
Date: 2010-09-17
Agency: Office of the Assistant Secretary for Administration and Management, Department of Labor
The Department of Labor, as part of its continuing effort to reduce paperwork and respondent burden, conducts a pre-clearance consultation program to provide the general public and Federal agencies with an opportunity to comment on the proposed continued collection of information in accordance with the Paperwork Reduction Act of 1995 (PRA) [44 U.S.C. 3506(c)(2)(A)]. This program helps to ensure that requested data can be provided in the desired format, reporting burden (time and financial resources) is minimized, collection instruments are clearly understood, and the impact of collection requirements on respondents can be properly assessed. The Department notes that a Federal agency cannot conduct or sponsor a collection of information unless it is approved by the Office of Management and Budget (OMB) under the PRA, and displays a currently valid OMB control number, and the public is not required to respond to a collection of information unless it displays a currently valid OMB control number. Also, notwithstanding any other provision of law, no person may be subject to penalty for failing to comply with a collection of information if the collection of information does not display a currently valid OMB control number. See 5 U.S.C. 1320.5(a) and 1320.6.
Approval and Promulgation of State Implementation Plan Revisions; State of North Dakota; Interstate Transport of Pollution for the 1997 PM2.5
Document Number: 2010-23292
Type: Proposed Rule
Date: 2010-09-17
Agency: Environmental Protection Agency
The Environmental Protection Agency is proposing partial approval of the State Implementation Plan (SIP) revisions called ``Interstate Transport of Air Pollution'' addressing the ``interference with maintenance'' requirement of Clean Air Act (CAA) section 110(a)(2)(D)(i) for the 1997 fine particulate matter (PM2.5) and 8-hour ozone National Ambient Air Quality Standards (NAAQS). In this action EPA proposes to approve the North Dakota Interstate Transport SIP sections that address the requirements of section 110(a)(2)(D)(i) prohibiting a state's emissions from interfering with maintenance by any other state of the 1997 PM2.5 and 8-hour ozone NAAQS. This action is being taken under section 110 of the CAA.
Approval and Promulgation of Implementation Plans; Oklahoma; State Implementation Plan Revisions for Interstate Transport of Pollution, Prevention of Significant Deterioration, Nonattainment New Source Review, Source Registration and Emissions Reporting and Rules of Practice and Procedure
Document Number: 2010-23291
Type: Proposed Rule
Date: 2010-09-17
Agency: Environmental Protection Agency
EPA is proposing to approve part of a State Implementation Plan (SIP) revision submitted by the State of Oklahoma for the purpose of addressing the ``good neighbor'' provisions of Clean Air Act (the Act or CAA) section 110(a)(2)(D)(i) for the 1997 8-hour ozone National Ambient Air Quality Standards (NAAQS or standards) and the 1997 fine particulate matter (PM2.5) NAAQS. This SIP revision satisfies a portion of the State's obligation to submit a SIP revision that demonstrates that adequate provisions are in place to prohibit air emissions from adversely affecting another State's air quality through interstate transport. In this action, EPA is proposing to approve the Oklahoma Interstate Transport SIP provisions that address the requirement of section 110(a)(2)(D)(i)(II) that emissions from sources in Oklahoma do not interfere with measures required in the SIP of any other State under part C of the CAA to prevent ``significant deterioration of air quality.'' EPA is also proposing to approve portions of the revision to the Oklahoma SIP submitted on February 14, 2002, which relate to Prevention of Significant Deterioration (PSD) and Nonattainment New Source Review (NNSR) for major sources, source registration and emissions reporting and other rules of practice and procedure (except for revisions relating to minor sources). Finally, for purposes of the 1997 8-hour ozone NAAQS, EPA also is proposing to approve the portions of the SIP revision submitted on June 24, 2010 to include nitrogen oxides (NOX) as an ozone precursor in Oklahoma's PSD SIP. This action is being taken under section 110 and parts C and D of the Act.
Fisheries of the South Atlantic and Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR); assessment webinar 7 for SEDAR 22 yellowedge grouper and tilefish; Public Meeting
Document Number: 2010-23290
Type: Notice
Date: 2010-09-17
Agency: Department of Commerce, National Oceanic and Atmospheric Administration
The SEDAR 22 assessments of the Gulf of Mexico stocks of yellowedge grouper and tilefish will consist of a series of workshops and webinars: a Data Workshop, a series of Assessment webinars, and a Review Workshop. See SUPPLEMENTARY INFORMATION.
Open Meeting of the President's Economic Recovery Advisory Board (the PERAB)
Document Number: 2010-23289
Type: Notice
Date: 2010-09-17
Agency: Department of the Treasury, Department of Treasury
The President's Economic Recovery Advisory Board will meet on October 4, 2010, in the White House Roosevelt Room, 1600 Pennsylvania Avenue, NW., Washington, DC, beginning at 2 p.m. Eastern Time. The meeting will be open to the public via live webcast at https:// www.whitehouse.gov/live.
Pesticide Product Registrations; Conditional Approval
Document Number: 2010-23288
Type: Notice
Date: 2010-09-17
Agency: Environmental Protection Agency
This notice announces Agency approval of applications submitted by Cheminova A/S, c/o Cheminova, Inc., to conditionally register the pesticide products Cheminova Flutriafol Technical and TOPGUARD Fungicide containing a new active ingredient not included in any previously registered products pursuant to the provisions of section 3(c)(7)(C) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended.
Pipeline Safety: Request for Special Permit and Availability of Draft Environmental Assessment
Document Number: 2010-23287
Type: Notice
Date: 2010-09-17
Agency: Pipeline and Hazardous Materials Safety Administration, Department of Transportation
PHMSA is providing an additional public comment period regarding a special permit request from Texas Eastern Transmission, L.P., for relief from 49 CFR 192.112 and 192.620. PHMSA had previously provided notice of its intent to consider the special permit request and an opportunity for public comment on April 23, 2009 (74 FR 4296). PHMSA is also providing notice of the availability of a Draft Environmental Assessment prepared in relation to this request for a special permit. Also, since the April 23, 2009 Federal Register notice, Texas Eastern Transmission, L.P., has modified its special permit request to reduce the length of its pipeline that would be subject to the request. The request and all pertinent information are available at https://www.Regulations.gov in Docket No. PHMSA-2008-0257. We invite the public and all concerned to review these documents and provide comments.
Advisory Committee on International Postal and Delivery Services
Document Number: 2010-23285
Type: Notice
Date: 2010-09-17
Agency: Department of State
As required by the Federal Advisory Committee Act, Public Law 92-463, the Department of State gives notice of a meeting of the Advisory Committee on International Postal and Delivery Services. This Committee has been formed in fulfillment of the provisions of the 2006 Postal Accountability and Enhancement Act (Pub. L. 109-435) and in accordance with the Federal Advisory Committee Act.
Culturally Significant Objects Imported for Exhibition Determinations: “Titian and the Golden Age of Venetian Painting: Masterpieces from the National Galleries of Scotland”
Document Number: 2010-23284
Type: Notice
Date: 2010-09-17
Agency: Department of State
Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation of Authority No. 234 of October 1, 1999, and Delegation of Authority No. 236-3 of August 28, 2000, I hereby determine that the objects to be included in the exhibition ``Titian and the Golden Age of Venetian Painting: Masterpieces from the National Galleries of Scotland,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan agreements with the foreign owners or custodians. I also determine that the exhibition or display of the exhibit objects at the High Museum of Art, Atlanta, GA, from on or about October 16, 2010, until on or about January 2, 2011; at the Minneapolis Institute of Arts, Minneapolis, MN, from on or about February 6, 2011 to on or about May 1, 2011; at the Museum of Fine Arts, Houston, TX, from on or about May 21, 2011, to on or about August 14, 2011, and at possible additional exhibitions or venues yet to be determined, is in the national interest. Public Notice of these Determinations is ordered to be published in the Federal Register.
Pilot, Flight Instructor, and Pilot School Certification
Document Number: 2010-23283
Type: Rule
Date: 2010-09-17
Agency: Federal Aviation Administration, Department of Transportation
The Federal Aviation Administration (FAA) is making minor technical changes to a final rule published in the Federal Register on August 21, 2009. That final rule revised the training, qualification, certification, and operating requirements for pilots, flight instructors, ground instructors, and pilot schools. Through this technical amendment, we are clarifying the intent of Sec. 141.5(d) and reinserting language that was inadvertently removed pertaining to special courses of training under appendix K of part 141.
Missouri Disaster #MO-00040
Document Number: 2010-23282
Type: Notice
Date: 2010-09-17
Agency: Small Business Administration, Agencies and Commissions
This is a notice of an Administrative declaration of a disaster for the State of Missouri dated 09/10/2010. Incident: Severe Storms, Flooding, Flash Flooding, High Winds, Hail and Tornadoes Incident Period: 06/12/2010 through 07/31/2010.
Iowa Disaster Number IA-00026
Document Number: 2010-23281
Type: Notice
Date: 2010-09-17
Agency: Small Business Administration, Agencies and Commissions
This is an amendment of the Presidential declaration of a major disaster for Public Assistance Only for the State of Iowa (FEMA- 1930-DR), dated 07/29/2010. Incident: Severe Storms, Flooding, and Tornadoes. Incident Period: 06/01/2010 and continuing. Effective Date: 09/09/2010. Physical Loan Application Deadline Date: 09/27/2010. Economic Injury (Eidl) Loan Application Deadline Date: 04/29/2011.
Agency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Consumer Focus Groups
Document Number: 2010-23280
Type: Notice
Date: 2010-09-17
Agency: Consumer Product Safety Commission, Agencies and Commissions
The Consumer Product Safety Commission (``CPSC'' or ``Commission'') is announcing that a proposed collection of information has been submitted to the Office of Management and Budget (``OMB'') for review and clearance under the Paperwork Reduction Act of 1995.
Special Local Regulation; Monongahela River, Pittsburgh, PA
Document Number: 2010-23279
Type: Rule
Date: 2010-09-17
Agency: Coast Guard, Department of Homeland Security
The Coast Guard is establishing a special local regulation from mile marker 2.2 (Southside Riverfront Park Boat Ramp) on the Monongahela River to mile marker 2.7 (27th Street), extending 100 feet out from the left descending bank. This special local regulation is needed to safeguard participants of the Pittsburgh Dragon Boat Festival from the hazards imposed by marine traffic. Entry into the regulated area is prohibited, unless specifically authorized by the Captain of the Port Pittsburgh or a designated representative.
Submission for OMB Review; Comment Request
Document Number: 2010-23278
Type: Notice
Date: 2010-09-17
Agency: Department of Commerce
Loan Guaranty: Assistance to Eligible Individuals in Acquiring Specially Adapted Housing
Document Number: 2010-23277
Type: Rule
Date: 2010-09-17
Agency: Department of Veterans Affairs
This document amends the Department of Veterans Affairs' (VA's) Loan Guaranty regulations concerning assistance to eligible individuals in acquiring specially adapted housing. These changes improve the readability of the regulations; provide further detail about longstanding program policies; and address legislation, policy changes, and a VA Office of the General Counsel legal opinion.
Center for Scientific Review; Notice of Closed Meetings
Document Number: 2010-23275
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services, National Institutes of Health
Iowa; Amendment No. 6 to Notice of a Major Disaster Declaration
Document Number: 2010-23274
Type: Notice
Date: 2010-09-17
Agency: Federal Emergency Management Agency, Department of Homeland Security
This notice amends the notice of a major disaster declaration for the State of Iowa (FEMA-1930-DR), dated July 29, 2010, and related determinations.
Procurement List Additions and Deletions
Document Number: 2010-23273
Type: Notice
Date: 2010-09-17
Agency: Committee for Purchase From People Who Are Blind or Severely Disabled, Agencies and Commissions
This action adds a product and a service to the Procurement List that will be furnished by nonprofit agencies employing persons who are blind or have other severe disabilities, and deletes products and services from the Procurement List previously furnished by such agencies.
Procurement List Proposed Additions and Deletion
Document Number: 2010-23272
Type: Notice
Date: 2010-09-17
Agency: Committee for Purchase From People Who Are Blind or Severely Disabled, Agencies and Commissions
The Committee is proposing to add products to the Procurement List that will be furnished by the nonprofit agencies employing persons who are blind or have other severe disabilities and to delete a product previously furnished by such agency.
Iowa; Amendment No. 1 to Notice of a Major Disaster Declaration
Document Number: 2010-23271
Type: Notice
Date: 2010-09-17
Agency: Federal Emergency Management Agency, Department of Homeland Security
This notice amends the notice of a major disaster declaration for the State of Iowa (FEMA-1928-DR), dated July 27, 2010, and related determinations.
Center for Scientific Review; Notice of Closed Meeting
Document Number: 2010-23270
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services, National Institutes of Health
Endangered and Threatened Species; Take of Anadromous Fish
Document Number: 2010-23269
Type: Notice
Date: 2010-09-17
Agency: Department of Commerce, National Oceanic and Atmospheric Administration
Notice is hereby given that NMFS has received three scientific research permit application requests relating to Pacific salmon. The proposed research is intended to increase knowledge of species listed under the Endangered Species Act (ESA) and to help guide management and conservation efforts. The applications may be viewed online at: https://apps.nmfs.noaa.gov/preview/previewopenfor comment.cfm
National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting
Document Number: 2010-23268
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services, National Institutes of Health
Pacific Halibut Fisheries; Limited Access for Guided Sport Charter Vessels in Alaska
Document Number: 2010-23267
Type: Rule
Date: 2010-09-17
Agency: Department of Commerce, National Oceanic and Atmospheric Administration
NMFS issues regulations amending the limited access program for charter vessels in the guided sport fishery for Pacific halibut in the waters of International Pacific Halibut Commission Regulatory Area 2C (Southeast Alaska) and Area 3A (Central Gulf of Alaska). These regulations revise the method of assigning angler endorsements to charter halibut permits to more closely align each endorsement with the greatest number of charter vessel anglers reported for each vessel that a charter business used to qualify for a charter halibut permit. This action is necessary to achieve the halibut fishery management goals of the North Pacific Fishery Management Council.
Distribution of the 2004 and 2005 Cable Royalty Funds
Document Number: 2010-23266
Type: Notice
Date: 2010-09-17
Agency: Copyright Royalty Board, Library of Congress, Library of Congress, Agencies and Commissions
The Copyright Royalty Judges are announcing the final Phase I distribution of cable royalty funds for the years 2004 and 2005.
National Institute of Mental Health; Notice of Closed Meetings
Document Number: 2010-23265
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services, National Institutes of Health
Digital Performance Right in Sound Recordings and Ephemeral Recordings
Document Number: 2010-23264
Type: Rule
Date: 2010-09-17
Agency: Copyright Royalty Board, Library of Congress, Library of Congress, Agencies and Commissions
The Copyright Royalty Judges are announcing their determination regarding the minimum fee to be paid by Noncommercial Webcasters under two statutory licenses, permitting certain digital performances of sound recordings and the making of ephemeral recordings, in response to an order of remand by the United States Court of Appeals for the District of Columbia Circuit.
Proposed Collection; Comment Request; Recruitment and Screening for the Insight Into Determination of Exceptional Aging and Longevity (IDEAL) Study
Document Number: 2010-23263
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services, National Institutes of Health
In compliance with the requirement of Section 3506(c)(2)(A) of the Paperwork Reduction Act of 1995, for the opportunity for public comment on proposed data collection projects, the National Institute on Aging (NIA), the National Institutes of Health (NIH) will publish periodic summaries of proposed projects to be submitted to the Office of Management and Budget (OMB) for review and approval. Proposed Collection: Title: Recruitment and Screening for the Insight into Determination of Exceptional Aging and Longevity (IDEAL) Study. Type of Information Collection Request: NEW. Need and Use of Information Collection: The purpose of the project for is to conduct recruitment and screening for the IDEAL Study. A multifaceted recruitment approach will be used to reach the target audience in a wide variety of ways. Those who are interested in participating in the IDEAL study will be asked to complete a two stage recruitment process consisting of a telephone interview and a physical exam. The Stage One interview consists of questions concerning demographics, physical ability, health status, and medical conditions. Those who are eligible after completing the telephone interview will be asked to complete the second stage of the screening process. The physical examination is a modified version of the full BLSA assessment protocol consisting of the following components: general appearance; vital signs; chest and heart auscultation; sensory systems including vision, hearing, sensory proprioception, neuropathy and balance; and movement and strength of the upper and lower extremities. In addition the potential participant will also be asked to complete physical performance tests, cognitive exams, an electrocardiogram and a blood draw. Frequency of Response: Once. Affected Public: Individuals or households. Type of Respondents: Healthy individuals who are at least 80 years of age. The annual reporting burden is as follows: Estimated Number of Respondents: 1,500; Estimated Number of Responses per Respondent: 1; Average Burden Hours per Response: 0.833; and Estimated Total Annual Burden Hours Requested: 701. There is no annualized cost to respondents. There are no Capital costs to report. There are no Operating or Maintenance Costs to report.
National Toxicology Program (NTP); NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM); Availability of Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) Test Method Evaluation Reports: In Vitro Ocular Safety Testing Methods and Strategies, and Routine Use of Topical Anesthetics, Systemic Analgesics, and Humane Endpoints for Ocular Safety Testing; Notice of Transmittal to Federal Agencies
Document Number: 2010-23262
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services
NICEATM announces availability of ICCVAM TMERs that provide recommendations regarding proposed in vitro ocular safety testing methods, testing strategies, and the routine use of anesthetics, analgesics, and humane endpoints for ocular safety testing to avoid or minimize any pain and distress. The reports and recommendations have been transmitted to Federal agencies for their review and response to ICCVAM in accordance with the ICCVAM Authorization Act of 2000. In the first report, ICCVAM recommends pain management procedures that should always be used to avoid or minimize pain and distress when it is determined necessary to conduct the rabbit eye test for regulatory safety purposes. In the second report, ICCVAM recommends that the Cytosensor microphysiometer (CM) test method can be used as a screening test to identify some types of substances that may cause permanent or severe eye injuries. ICCVAM also recommends that the CM test method can be used to determine if some types of substances will not cause sufficient injury to require hazard labeling for eye irritation. ICCVAM evaluated four other in vitro test methods for their usefulness and limitations for identifying substances with the potential to cause reversible and nonsevere ocular injuries, but concluded that the performance of these methods must be improved before they can be used for regulatory safety testing to classify such substances. The report includes ICCVAM recommendations for future studies that could potentially improve these test methods. In the third report, ICCVAM recommends further studies to characterize the usefulness and limitations of a non-animal in vitro testing strategy that uses three in vitro test methods. In the fourth report, ICCVAM recommends that a proposed low volume rabbit eye test (LVET) should not be used for regulatory testing due to performance issues when compared to the current standard rabbit eye test.
Agency Information Collection Activities: Submission for OMB Review; Comment Request
Document Number: 2010-23260
Type: Notice
Date: 2010-09-17
Agency: Department of Health and Human Services, Health Resources and Services Administration
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