Center for Scientific Review; Notice of Closed Meeting, 81630 [2010-32639]
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Federal Register / Vol. 75, No. 248 / Tuesday, December 28, 2010 / Notices
development and differentiation in
order to identify the critical stages
where dysfunction can lead to the onset
of breast cancer.
• Molecular biology laboratory tool
for sorting breast cancer positive and
negative cells so that further
comparative experiments can be
performed to understand the cellular
properties of the two sets of cells.
Advantages:
• Useful for in vitro and in vivo
assays: Using the GFP or luciferase
expression of these reporter plasmids,
researchers can identify cells expressing
various levels of GATA–3 and isolate
these different subsets in vitro. These
reporter constructs can also be
transfected into cells to measure
GATA–3 expression levels in vivo in
real time from hematopoietic and breast
cancer models.
• Possible identification of new
targets for breast cancer therapy: The
reporter plasmids could be utilized to
identify factors that serve to activate
GATA–3 in normal mammary cells or
inhibit GATA–3 expression in breast
cancer cells. Such factors could serve as
targets for novel breast cancer therapies.
Inventors: Hosein Kouros-Mehr
(formerly NCI) and Jeffrey E. Green
(NCI)
Selected Publications:
1. H. Kouros-Mehr, et al. GATA–3 and
the regulation of the mammary luminal
cell fate. Curr Opin Cell Biol. 2008
Apr;20(2):164–170. [PubMed: 18358709]
2. H. Kouros-Mehr, et al. GATA–3
links tumor differentiation and
dissemination in the luminal breast
cancer model. Cancer Cell 2008
Feb;13(2):141–152. [PubMed: 18242514]
3. H. Kouros-Mehr, et al. GATA–3
maintains the differentiation of the
luminal cell fate in the mammary gland.
Cell 2006 Dec 1;127(5):1041–1055.
[PubMed: 17129787]
Patent Status: HHS Reference No. E–
128–2009/0—Research Tool. Patent
protection is not being pursued for this
technology.
Licensing Status: Available for
licensing under a Biological Materials
License Agreement.
Licensing Contact: Samuel E. Bish,
Ph.D.; 301–435–5282;
bishse@mail.nih.gov.
Dated: December 21, 2010.
Richard U. Rodriguez,
Director, Division of Technology Development
and Transfer, Office of Technology Transfer,
National Institutes of Health.
[FR Doc. 2010–32671 Filed 12–27–10; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Biomedical
Imaging and Bioengineering; Notice of
Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Biomedical Imaging and Bioengineering
Special Emphasis Panel.
Date: March 16–18, 2011.
Time: 6 p.m. to 3 p.m.
Agenda: To review and evaluate grant
applications.
Place: Sheraton Fisherman’s Wharf Hotel,
2500 Mason Street, San Francisco, CA 94133.
Contact Person: Ruth Grossman, DDS,
Scientific Review Officer, National Institute
of Biomedical Imaging and Bioengineering,
National Institutes of Health, 6707
Democracy Boulevard, Room 960, Bethesda,
MD 20892, 301–496–8775,
grossmanrs@mail.nih.gov.
Dated: December 16, 2010.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 2010–32645 Filed 12–27–10; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Notice of
Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
PO 00000
Frm 00071
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individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; Member
Conflict: Cardiac Development.
Date: January 4, 2011.
Time: 3 p.m. to 4 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892.
(Telephone Conference Call).
Contact Person: Joseph Thomas Peterson,
PhD, Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 4118,
MSC 7814, Bethesda, MD 20892. 301–443–
8130.
This notice is being published less than 15
days prior to the meeting due to the timing
limitations imposed by the review and
funding cycle.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.306, Comparative Medicine;
93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393–93.396, 93.837–93.844,
93.846–93.878, 93.892, 93.893, National
Institutes of Health, HHS)
Dated: December 21, 2010.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 2010–32639 Filed 12–27–10; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Amended
Notice of Meeting
Notice is hereby given of a change in
the meeting of the Center for Scientific
Review Special Emphasis Panel, January
6, 2011, 1 p.m. to January 6, 2011, 3:30
p.m., National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892
which was published in the Federal
Register on December 16, 2010, 75 FR
78719–78720.
The meeting has been changed to an
Internet Assisted Meeting (IAM). The
meeting will be two days January 6,
2011, 9 a.m. to January 7, 2011, 5 p.m.
The meeting is closed to the public.
Dated: December 21, 2010.
Jennifer S. Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 2010–32638 Filed 12–27–10; 8:45 am]
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Agencies
[Federal Register Volume 75, Number 248 (Tuesday, December 28, 2010)]
[Notices]
[Page 81630]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2010-32639]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Notice of Closed Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is hereby given of the following
meeting.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications, the disclosure of which would
constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: Center for Scientific Review Special Emphasis
Panel; Member Conflict: Cardiac Development.
Date: January 4, 2011.
Time: 3 p.m. to 4 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, 6701 Rockledge Drive,
Bethesda, MD 20892. (Telephone Conference Call).
Contact Person: Joseph Thomas Peterson, PhD, Scientific Review
Officer, Center for Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 4118, MSC 7814, Bethesda, MD
20892. 301-443-8130.
This notice is being published less than 15 days prior to the
meeting due to the timing limitations imposed by the review and
funding cycle.
(Catalogue of Federal Domestic Assistance Program Nos. 93.306,
Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393-93.396, 93.837-93.844, 93.846-93.878, 93.892, 93.893,
National Institutes of Health, HHS)
Dated: December 21, 2010.
Jennifer S. Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 2010-32639 Filed 12-27-10; 8:45 am]
BILLING CODE 4140-01-P