Disease, Disability, and Injury Prevention and Control, 39544 [2010-16741]
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39544
Federal Register / Vol. 75, No. 131 / Friday, July 9, 2010 / Notices
TABLE 1.—ESTIMATED ANNUAL REPORTING BURDEN1
No. of
Respondents
Activity
Submission of rotational plans
for health warning label
statements
1 There
Annual Frequency
per Response
20
Total Annual
Responses
1
20
Total Hours
100
2,000
are no capital costs or operating and maintenance costs associated with this collection of information.
Dated: July 2, 2010.
Elaine L. Baker,
Director, Management Analysis and Services
Office, Centers for Disease Control and
Prevention.
Dated: July 2, 2010.
Leslie Kux,
Acting Assistant Commissioner for Policy.
[FR Doc. 2010–16805 Filed 7–8–10; 8:45 am]
BILLING CODE 4160–01–S
[FR Doc. 2010–16741 Filed 7–8–10; 8:45 am]
BILLING CODE 4163–18–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Disease Control and
Prevention
National Institutes of Health
Disease, Disability, and Injury
Prevention and Control
Special Emphasis Panel (SEP):
Preparedness and Emergency Response
Learning Centers (PERLC) Panel,
Request for Applications (RFA) TP10–
1001, Initial Review
In accordance with section 10(a)(2) of
the Federal Advisory Committee Act
(Pub. L. 92–463), the Centers for Disease
Control and Prevention (CDC),
announces the aforementioned meeting:
wwoods2 on DSK1DXX6B1PROD with NOTICES_PART 1
Hours per
Response
Times and Dates: 8:30 a.m.–5 p.m., July 27,
2010 (Closed). 8:30 a.m.–5 p.m., July 28, 2010
(Closed). 8:30 a.m.–5 p.m., July 29, 2010
(Closed).
Place: The W Atlanta Hotel-Perimeter,
Perimeter Center West, Atlanta, Georgia
30346, Telephone: (770) 396–6800.
Status: The meeting will be closed to the
public in accordance with provisions set
forth in Section 552b(c)(4) and (6), Title 5,
U.S.C., and the Determination of the Director,
Management Analysis and Services Office,
CDC, pursuant to Section 10(d) of Public Law
92–463.
Matters To Be Discussed: The meeting will
include the initial review, discussion, and
evaluation of applications received in
response to ‘‘Preparedness and Emergency
Response Learning Centers (PERLC) Panel,
RFA TP10–1001.’’
Agenda items are subject to change as
priorities dictate.
Contact Person for More Information:
Shoukat Qari, Senior Scientific Program
Official, Extramural Research Program, Office
of Public Health Preparedness and Response,
1600 Clifton Road, Mailstop D–44, Atlanta,
Georgia 30333, Telephone: (404) 639–7938,
E-mail: SQari@cdc.gov.
The Director, Management Analysis and
Services Office has been delegated the
authority to sign Federal Register notices
pertaining to announcements of meetings and
other committee management activities for
both CDC and the Agency for Toxic
Substances and Disease Registry.
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15:17 Jul 08, 2010
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Government-Owned Inventions;
Availability for Licensing
AGENCY: National Institutes of Health,
Public Health Service, HHS.
ACTION: Notice.
SUMMARY: The inventions listed below
are owned by an agency of the U.S.
Government and are available for
licensing in the U.S. in accordance with
35 U.S.C. 207 to achieve expeditious
commercialization of results of
Federally-funded research and
development. Foreign patent
applications are filed on selected
inventions to extend market coverage
for companies and may also be available
for licensing.
ADDRESSES: Licensing information and
copies of the U.S. patent applications
listed below may be obtained by writing
to the indicated licensing contact at the
Office of Technology Transfer, National
Institutes of Health, 6011 Executive
Boulevard, Suite 325, Rockville,
Maryland 20852–3804; telephone: 301/
496–7057; fax: 301/402–0220. A signed
Confidential Disclosure Agreement will
be required to receive copies of the
patent applications.
Identification of Cancer Stem Cells
Description of Invention: Cancer stem
cells (CSC) are thought to be responsible
for cancer initiation, maintenance, and
therapeutic failure. A hallmark of stem
cells is self-renewal via asymmetric cell
division (ACD) into daughter stem-cells
and cells predestined for differentiation.
Demonstration of fundamental stemcell’s traits such as ACD in cancers is
lacking. Label retaining cells are thought
to be enriched for stem-like cells. Label
retaining cells are thought to be the
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results of either very slow cycling cells
and/or cells undergoing ACD. This
invention is directed to the
identification, isolation and purification
of cancer stem cells by detecting
asymmetrically dividing cells and/or
label retaining cells. Detection of
asymmetric cell division via nonrandom chromosomal cosegregation
(ACD–NRCC) in various human cancers
defines a unique and novel class of
universal cancer stem cells, and
potentially suggests a novel mechanism
of carcinogenesis. The isolation of CSC
might be used as a basis for a potential
new strategy in cancer therapeutics. The
invention also might have some
implications in genetics and
regenerative medicine.
Applications
• This invention may provide a novel
way to target various cancers for
treatment.
• This invention maybe also useful in
regenerative medicine, i.e. spinal cord
injury (regeneration of neurons),
Alzheimer (regeneration of neurons) and
Parkinson’s disease regeneration of
neurons).
Development Status: Pre-clinical stage
of development.
Market
• Cancer is the second leading cause
of death in the U.S. The National Cancer
Institute estimates the overall annual
costs for cancer in the U.S. at $107
billion; $37 billion for direct medical
costs, $11 billion for morbidity costs
(cost of lost productivity), and $59
billion for mortality costs.
• According to statistics gathered by
the National Institutes of Health, more
than 10,000 Americans experience
spinal cord injuries each year and more
than 200,000 are living with permanent
paralysis in their arms or legs due to
spinal cord injury.
• Parkinson’s disease affects some
four million patients worldwide.
Approximately 50,000 Americans are
diagnosed with Parkinson’s disease each
year. Alzheimer Disease is estimated to
affect 5.09 million patients by 2010.
Inventors: Itzhak Avital, Hong-Wu
Xin, Danielle M. Hari (NCI)
Publication: Manuscript submitted.
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]]>Agencies
[Federal Register Volume 75, Number 131 (Friday, July 9, 2010)]
[Notices]
[Page 39544]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2010-16741]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
Disease, Disability, and Injury Prevention and Control
Special Emphasis Panel (SEP): Preparedness and Emergency Response
Learning Centers (PERLC) Panel, Request for Applications (RFA) TP10-
1001, Initial Review
In accordance with section 10(a)(2) of the Federal Advisory
Committee Act (Pub. L. 92-463), the Centers for Disease Control and
Prevention (CDC), announces the aforementioned meeting:
Times and Dates: 8:30 a.m.-5 p.m., July 27, 2010 (Closed). 8:30
a.m.-5 p.m., July 28, 2010 (Closed). 8:30 a.m.-5 p.m., July 29, 2010
(Closed).
Place: The W Atlanta Hotel-Perimeter, Perimeter Center West,
Atlanta, Georgia 30346, Telephone: (770) 396-6800.
Status: The meeting will be closed to the public in accordance
with provisions set forth in Section 552b(c)(4) and (6), Title 5,
U.S.C., and the Determination of the Director, Management Analysis
and Services Office, CDC, pursuant to Section 10(d) of Public Law
92-463.
Matters To Be Discussed: The meeting will include the initial
review, discussion, and evaluation of applications received in
response to ``Preparedness and Emergency Response Learning Centers
(PERLC) Panel, RFA TP10-1001.''
Agenda items are subject to change as priorities dictate.
Contact Person for More Information: Shoukat Qari, Senior
Scientific Program Official, Extramural Research Program, Office of
Public Health Preparedness and Response, 1600 Clifton Road, Mailstop
D-44, Atlanta, Georgia 30333, Telephone: (404) 639-7938, E-mail:
SQari@cdc.gov.
The Director, Management Analysis and Services Office has been
delegated the authority to sign Federal Register notices pertaining
to announcements of meetings and other committee management
activities for both CDC and the Agency for Toxic Substances and
Disease Registry.
Dated: July 2, 2010.
Elaine L. Baker,
Director, Management Analysis and Services Office, Centers for Disease
Control and Prevention.
[FR Doc. 2010-16741 Filed 7-8-10; 8:45 am]
BILLING CODE 4163-18-P
