National Library of Medicine; Notice of Meeting, 69351 [E9-30949]
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Federal Register / Vol. 74, No. 250 / Thursday, December 31, 2009 / Notices
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using inexpensive starting materials and
facile reactions. Thus, it opens the
possibility that an effective drug
treatment for HIV could be made
available to much larger populations.
These thioesters may also be used as an
active component in topical
applications that serve as a barrier to
HIV infection.
Inventors: John K. Inman (NIAID),
Atul Goel (NCI), Ettore Appella (NCI),
James A. Turpin (NIAID), Marco Schito
(NCI)
Publications:
1. ML Schito, A Goel, Y Song, JK
Inman, RJ Fattah, WG Rice, JA Turpin,
A Sher, E Appella. In vitro antiviral
activity of novel human
immunodeficiency virus type 1
nucleocapsid p7 zinc finger inhibitors
in a transgenic murine model. AIDS Res
Hum Retroviruses. 2003 Feb;19(2):91–
101.
2. P Srivastava, M Schito, RJ Fattah,
T Hara, T Hartman, RW Buckheit Jr, JA
Turpin, JK Inman, E Appella.
Optimization of unique, uncharged
thioesters as inhibitors of HIV
replication. Bioorg Med Chem. 2004 Dec
15;12(24):6437–6450.
3. LM Jenkins, JC Byrd, T Hara, P
Srivastava, SJ Mazu, SJ Stahl, JK Inman,
E Appella, JG Omichinski, P Legault.
Studies on the mechanism of
inactivation of the HIV–1 nucleocapsid
protein NCp7 with 2mercaptobenzamide thioesters. J Med
Chem. 2005 Apr 21;48(8):2847–2858.
4. V Basrur, Y Song, SJ Mazur, Y
Higashimoto, JA Turpin, WG Rice, JK
Inman, E Appella. Inactivation of HIV–
1 nucleocapsid protein P7 by
pyridinioalkanoyl thioesters.
Characterization of reaction products
and proposed mechanism of action. J
Biol Chem. 2000 May 19;275(20):14890–
14897.
5. JA Turpin, Y Song, JK Inman, M
Huang, A Wallqvist, A Maynard, DG
Covell, WG Rice, E Appella. Synthesis
and biological properties of novel
pyridinioalkanoyl thiolesters (PATE) as
anti-HIV–1 agents that target the viral
nucleocapsid protein zinc fingers. J Med
Chem. 1999 Jan 14;42(1):67–86.
Patent Status:
• U.S. Patent No. 7,528,274 issued 05
May 2009 (HHS Reference No. E–329–
2000/0–US–06)
• U.S. Patent Application No. 12/
414,321 filed 30 Mar 2009 (HHS
Reference No. E–329–2000/0–US–07)
Licensing Status: Available for
licensing.
Licensing Contact: Sally H. Hu, PhD,
MBA; 301–435–5605; hus@mail.nih.gov.
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Dated: December 23, 2009.
Richard U. Rodriguez,
Director, Division of Technology Development
and Transfer, Office of Technology Transfer,
National Institutes of Health.
[FR Doc. E9–31072 Filed 12–30–09; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Library of Medicine; Notice of
Meeting
Pursuant to section 10(a) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be open to the
public, with attendance limited to space
available. Individuals who plan to
attend and need special assistance, such
as sign language interpretation or other
reasonable accommodations, should
notify the Contact Person listed below
in advance of the meeting.
Name of Committee: National Library of
Medicine Special Emphasis Panel.
Date: February 17, 2010.
Time: 12 p.m. to 2 p.m.
Agenda: To provide concept review of
proposed grant applications.
Place: National Library of Medicine, 6705
Rockledge Drive, Bethesda, MD 20817.
(Telephone Conference Call)
Contact Person: Zoe E. Huang, MD,
Scientific Review Officer, Division of
Extramural Programs, National Library of
Medicine, National Institutes of Health, 6705
Rockledge Drive, Suite 301, MSC 7968,
Bethesda, MD 20892–7968, 301–594–4937,
huangz©mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.879, Medical Library
Assistance, National Institutes of Health,
HHS)
Dated: December 22, 2009.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. E9–30949 Filed 12–30–09; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Agency for Healthcare Research and
Quality
In accordance with section 10(d) of
the Federal Advisory Committee Act (5
U.S.C., Appendix 2), announcement is
made of a Health Care Policy and
Research Special Emphasis Panel (SEP)
meeting.
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A Special Emphasis Panel is a group
of experts in fields related to health care
research who are invited by the Agency
for Healthcare Research and Quality
(AHRQ), and agree to be available, to
conduct on an as needed basis,
scientific reviews of applications for
AHRQ support. Individual members of
the Panel do not attend regularlyscheduled meetings and do not serve for
fixed terms or a long period of time.
Rather, they are asked to participate in
particular review meetings which
require their type of expertise.
Substantial segments of the upcoming
SEP meeting listed below will be closed
to the public in accordance with the
Federal Advisory Committee Act,
section 10(d) of 5 U.S.C., Appendix 2
and 5 U.S.C. 552b(c)(6). Grant
applications for the Accelerating
Development of Methods for the Study
of Complex Patients (R21) applications
are to be reviewed and discussed at this
meeting. These discussions are likely to
reveal personal information concerning
individuals associated with the
applications. This information is
exempt from mandatory disclosure
under the above-cited statutes.
SEP Meeting on: AHRQ Developing
Prospective Practice-based Comparative
Effectiveness Research Clinical Registries:
Orthopedic Devices, Drugs, and Procedures
(P50).
Date: January 20, 2010 (Open on January
20 from 8 a.m. to 8:15 a.m. and closed for the
remainder of the meeting).
Place: Marriott RIO, Conference Room
TBD, 9751 Washingtonian Blvd.,
Gaithersburg, MD 20878.
Contact Person: Anyone wishing to obtain
a roster of members, agenda or minutes of the
nonconfidential portions of this meeting
should contact Mrs. Bonnie Campbell,
Committee Management Officer, Office of
Extramural Research, Education and Priority
Populations, AHRQ, 540 Gaither Road, Room
2038, Rockville, Maryland 20850, Telephone
(301) 427–1554.
Agenda items for this meeting are subject
to change as priorities dictate.
Dated: December 15, 2009.
Carolyn M. Clancy,
Director.
[FR Doc. E9–30956 Filed 12–30–09; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Notice of Meeting
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69351
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National Institute on Drug Abuse;
Notice of Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meetings.
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[Federal Register Volume 74, Number 250 (Thursday, December 31, 2009)]
[Notices]
[Page 69351]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-30949]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Library of Medicine; Notice of Meeting
Pursuant to section 10(a) of the Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is hereby given of the following
meeting.
The meeting will be open to the public, with attendance limited to
space available. Individuals who plan to attend and need special
assistance, such as sign language interpretation or other reasonable
accommodations, should notify the Contact Person listed below in
advance of the meeting.
Name of Committee: National Library of Medicine Special Emphasis
Panel.
Date: February 17, 2010.
Time: 12 p.m. to 2 p.m.
Agenda: To provide concept review of proposed grant
applications.
Place: National Library of Medicine, 6705 Rockledge Drive,
Bethesda, MD 20817. (Telephone Conference Call)
Contact Person: Zoe E. Huang, MD, Scientific Review Officer,
Division of Extramural Programs, National Library of Medicine,
National Institutes of Health, 6705 Rockledge Drive, Suite 301, MSC
7968, Bethesda, MD 20892-7968, 301-594-4937,
huangz(copyright)mail.nih.gov.
(Catalogue of Federal Domestic Assistance Program Nos. 93.879,
Medical Library Assistance, National Institutes of Health, HHS)
Dated: December 22, 2009.
Jennifer Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. E9-30949 Filed 12-30-09; 8:45 am]
BILLING CODE 4140-01-M