Draft Toxicological Review of cis- and trans-1,2-Dichloroethylene: In Support of the Summary Information in the Integrated Risk Information System (IRIS), 58014-58015 [E9-27049]

Download as PDF 58014 Federal Register / Vol. 74, No. 216 / Tuesday, November 10, 2009 / Notices ENVIRONMENTAL PROTECTION AGENCY [FRL–8978–5; Docket ID No. EPA–HQ–ORD– 2009–0348] Draft Toxicological Review of cis- and trans-1,2-Dichloroethylene: In Support of the Summary Information in the Integrated Risk Information System (IRIS) srobinson on DSKHWCL6B1PROD with NOTICES AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of peer-review workshop. SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for external scientific peer review, will convene an independent panel of experts and organize and conduct an external peer-review workshop to review the external review draft document titled, ‘‘Toxicological Review of cis- and trans-1,2-Dichloroethylene: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ (EPA/635/R–09/006). The draft document was prepared by the National Center for Environmental Assessment (NCEA) within EPA’s Office of Research and Development. EPA previously announced the 60-day public comment period (ending November 23, 2009) for the draft document in the Federal Register on September 24, 2009 (74 FR 48733). EPA will consider public comments and recommendations from the expert panel workshop as EPA finalizes the draft document. The public comment period and the external peer-review workshop are separate processes that provide opportunities for all interested parties to comment on the document. EPA intends to forward public comments submitted in accordance with the September 24, 2009, Federal Register notice (74 FR 48733) to Versar, Inc. for consideration by the external peer-review panel prior to the workshop. EPA is releasing this draft document solely for the purpose of predissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. Versar, Inc. invites the public to register to attend this workshop as observers. In addition, Versar, Inc. invites the public to give oral and/or provide written comments at the workshop regarding the draft document under review. Space is limited, and reservations will be accepted on a firstcome, first-served basis. The draft document and EPA’s peer-review charge VerDate Nov<24>2008 16:45 Nov 09, 2009 Jkt 220001 are available primarily via the Internet on NCEA’s home page under the Recent Additions and Publications menus at http://www.epa.gov/ncea. In preparing a final report, EPA will consider Versar’s report of the comments and recommendations from the external peer-review workshop and any public comments that EPA receives. DATES: The peer-review panel workshop will begin on December 17, 2009 at 8:30 a.m. and end at 4 p.m. ADDRESSES: The peer-review workshop will be held at the Marriott Courtyard Arlington Crystal City/Reagan National Airport, 2899 Jefferson Davis Highway, Arlington, VA 22202, phone: 703–549– 3434. The EPA contractor, Versar, Inc., is organizing, convening, and conducting the peer-review workshop. To attend the workshop, register by December 10, 2009, by calling Versar, Inc. at 703–750–3000, ext. 545, or toll free at 1–800–2–VERSAR (ask for Kathy Coon, the cis- and trans-1,2Dichloroethylene peer review workshop coordinator), sending a facsimile to 703–642–6954 (please reference the ‘‘cis- and trans-1,2-Dichloroethylene Workshop’’ and include your name, title, affiliation, full address and contact information), or sending an e-mail to kscoon@versar.com (subject line: cisand trans-1,2-Dichloroethylene Peer Review Workshop). The draft ‘‘Toxicological Review of cis- and trans-1,2-Dichloroethylene: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ is available primarily via the Internet on the National Center for Environmental Assessment’s home page under the Recent Additions and Publications menus at http:// www.epa.gov/ncea. A limited number of paper copies are available from the Information Management Team, NCEA; telephone: 703–347–8561; facsimile: 703–347–8691. If you are requesting a paper copy, please provide your name, mailing address, and the document title, ‘‘Toxicological Review of cis- and trans1,2-Dichloroethylene: In Support of Summary Information on the Integrated Risk Information System (IRIS).’’ Copies are not available from Versar, Inc. Information on Services for Individuals with Disabilities: EPA welcomes public attendance at the ‘‘cisand trans-1,2-Dichloroethylene peerreview workshop’’ and will make every effort to accommodate persons with disabilities. For information on access or services for individuals with disabilities, please contact Versar, Inc. by phone at (703) 750–3000, ext. 545, or toll free at 1–800–2–VERSAR (ask for Kathy Coon, the cis- and trans-1,2- PO 00000 Frm 00026 Fmt 4703 Sfmt 4703 Dichloroethylene peer review workshop coordinator), or by e-mail at kscoon@versar.com (subject line: cisand trans-1,2-Dichloroethylene Peer Review Workshop), preferably at least 10 days prior to the meeting, to give as much time as possible to process your request. FOR FURTHER INFORMATION CONTACT: Questions regarding information, registration, access or services for individuals with disabilities, or logistics for the external peer-review workshop should be directed to Versar, Inc., 6850 Versar Center, Springfield, VA 22151; telephone: 703–750–3000, ext. 545, or toll free at 1–800–2–VERSAR (ask for Kathy Coon, the cis- and trans-1,2Dichloroethylene peer review workshop coordinator), facsimile: 703–642–6954 (please reference the ‘‘cis- and trans-1,2Dichloroethylene Workshop’’ and include your name, title, affiliation, full address and contact information), or email: kscoon@versar.com (subject line: cis- and trans-1,2-Dichloroethylene Peer Review Workshop). To request accommodation of a disability, please contact Kathy Coon (at the numbers and e-mail listed above), preferably at least 10 days prior to the meeting, to give as much time as possible to process your request. If you have questions about the document, please contact Audrey Galizia, National Center for Environmental Assessment (NCEA), telephone: 732–906–6887; facsimile: 732–452–6429; or e-mail galizia.audrey@epa.gov. SUPPLEMENTARY INFORMATION: Information About IRIS IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at http://www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 540 chemical substances that may be used to support the first two steps (hazard identification and doseresponse evaluation) of a risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with specific exposure information, government and private entities can use IRIS data to help characterize public health risks of chemical substances in a site-specific situation and thereby E:\FR\FM\10NON1.SGM 10NON1 Federal Register / Vol. 74, No. 216 / Tuesday, November 10, 2009 / Notices support risk management decisions designed to protect public health. Dated: October 29, 2009. Rebecca Clark, Acting Director, National Center for Environmental Assessment. [FR Doc. E9–27049 Filed 11–9–09; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY [FRL–8978–7; Docket ID No. EPA–HQ–ORD– 2009–0245] Draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of the Summary Information on the Integrated Risk Information System (IRIS) Environmental Protection Agency (EPA). ACTION: Notice of peer-review workshop. srobinson on DSKHWCL6B1PROD with NOTICES AGENCY: SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for external scientific peer review, will convene an independent panel of experts and organize and conduct an external peer-review workshop to review the external review draft document titled, ‘‘Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ (EPA/635/R–08/016). The draft document was prepared by the National Center for Environmental Assessment (NCEA) within EPA’s Office of Research and Development. EPA previously announced the 60-day public comment period (ending November 23, 2009) for the draft document in the Federal Register on September 23, 2009 (74 FR 48539). EPA will consider public comments and recommendations from the expert panel workshop as EPA finalizes the draft document. The public comment period and the external peer-review workshop are separate processes that provide opportunities for all interested parties to comment on the document. EPA intends to forward public comments submitted in accordance with the September 23, 2009, Federal Register notice (74 FR 48539) to Versar, Inc., for consideration by the external peer-review panel prior to the workshop. EPA is releasing this draft document solely for the purpose of predissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. VerDate Nov<24>2008 16:45 Nov 09, 2009 Jkt 220001 Versar, Inc. invites the public to register to attend this workshop as observers. In addition, Versar, Inc. invites the public to give oral and/or provide written comments at the workshop regarding the draft document under review. Space is limited, and reservations will be accepted on a firstcome, first-served basis. The draft document and EPA’s peer-review charge are available primarily via the Internet on NCEA’s home page under the Recent Additions and Publications menus at http://www.epa.gov/ncea. In preparing a final report, EPA will consider Versar Inc.’s report of the comments and recommendations from the external peer-review workshop and any public comments that EPA receives. DATES: The peer-review panel workshop will begin on December 14, 2009, at 9 a.m. and end at 5 p.m. ADDRESSES: The peer-review workshop will be held at Marriott Courtyard Arlington Crystal City/Reagan National Airport, 2899 Jefferson Davis Highway, Arlington, VA 22202, telephone 703– 549–3434. The EPA contractor, Versar, Inc. is organizing, convening, and conducting the peer-review workshop. To attend the workshop, register by December 7, 2009, by calling Versar, Inc. at 703–750–3000 extension 6897, sending a facsimile to 703–642–6954 or sending an e-mail to hriester@versar.com. You may also register via the Internet at http:// epa.versar.com/hydrogencyanide. The draft ‘‘Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ is available primarily via the Internet on the National Center for Environmental Assessment’s home page under the Recent Additions and Publications menus at http:// www.epa.gov/ncea. A limited number of paper copies are available from the Information Management Team, NCEA; telephone: 703–347–8561; facsimile: 703–347–8691. If you are requesting a paper copy, please provide your name, mailing address, and the document title, ‘‘Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of Summary Information on the Integrated Risk Information System (IRIS).’’ Copies are not available from Versar, Inc. Information on Services for Individuals with Disabilities: EPA welcomes public attendance at the ‘‘Hydrogen Cyanide and Cyanide Salts peer-review workshop’’ and will make every effort to accommodate persons with disabilities. For information on access or services for individuals with PO 00000 Frm 00027 Fmt 4703 Sfmt 4703 58015 disabilities, please contact Versar, Inc, preferably at least 10 days prior to the meeting, to give as much time as possible to process your request. FOR FURTHER INFORMATION CONTACT: Questions regarding information, registration, access or services for individuals with disabilities, or logistics for the external peer-review workshop should be directed to Versar. If you have questions about the document, please contact Kathleen Newhouse, National Center for Environmental Assessment (NCEA), (8601P) 1200 Pennsylvania Ave., Washington DC, 20460; telephone: 703– 347–8641; facsimile: 703–347–8689; or e-mail: newhouse.kathleen@epa.gov. SUPPLEMENTARY INFORMATION: I. Information About IRIS IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at http://www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 540 chemical substances that may be used to support the first two steps (hazard identification and doseresponse evaluation) of a risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with specific exposure information, government and private entities can use IRIS data to help characterize public health risks of chemical substances in a site-specific situation and thereby support risk management decisions designed to protect public health. Dated: October 29, 2009. Rebecca Clark, Acting Director, National Center for Environmental Assessment. [FR Doc. E9–27051 Filed 11–9–09; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY [FRL–8978–6; Docket ID No. EPA–HQ–ORD– 2009–0203] Draft Toxicological Review of Trichloroacetic Acid: In Support of the Summary Information in the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). E:\FR\FM\10NON1.SGM 10NON1

Agencies

[Federal Register Volume 74, Number 216 (Tuesday, November 10, 2009)]
[Notices]
[Pages 58014-58015]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-27049]



[[Page 58014]]

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ENVIRONMENTAL PROTECTION AGENCY

[FRL-8978-5; Docket ID No. EPA-HQ-ORD-2009-0348]


Draft Toxicological Review of cis- and trans-1,2-
Dichloroethylene: In Support of the Summary Information in the 
Integrated Risk Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of peer-review workshop.

-----------------------------------------------------------------------

SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for 
external scientific peer review, will convene an independent panel of 
experts and organize and conduct an external peer-review workshop to 
review the external review draft document titled, ``Toxicological 
Review of cis- and trans-1,2-Dichloroethylene: In Support of Summary 
Information on the Integrated Risk Information System (IRIS)'' (EPA/
635/R-09/006). The draft document was prepared by the National Center 
for Environmental Assessment (NCEA) within EPA's Office of Research and 
Development. EPA previously announced the 60-day public comment period 
(ending November 23, 2009) for the draft document in the Federal 
Register on September 24, 2009 (74 FR 48733). EPA will consider public 
comments and recommendations from the expert panel workshop as EPA 
finalizes the draft document.
    The public comment period and the external peer-review workshop are 
separate processes that provide opportunities for all interested 
parties to comment on the document. EPA intends to forward public 
comments submitted in accordance with the September 24, 2009, Federal 
Register notice (74 FR 48733) to Versar, Inc. for consideration by the 
external peer-review panel prior to the workshop.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination.
    Versar, Inc. invites the public to register to attend this workshop 
as observers. In addition, Versar, Inc. invites the public to give oral 
and/or provide written comments at the workshop regarding the draft 
document under review. Space is limited, and reservations will be 
accepted on a first-come, first-served basis. The draft document and 
EPA's peer-review charge are available primarily via the Internet on 
NCEA's home page under the Recent Additions and Publications menus at 
http://www.epa.gov/ncea. In preparing a final report, EPA will consider 
Versar's report of the comments and recommendations from the external 
peer-review workshop and any public comments that EPA receives.

DATES: The peer-review panel workshop will begin on December 17, 2009 
at 8:30 a.m. and end at 4 p.m.

ADDRESSES: The peer-review workshop will be held at the Marriott 
Courtyard Arlington Crystal City/Reagan National Airport, 2899 
Jefferson Davis Highway, Arlington, VA 22202, phone: 703-549-3434. The 
EPA contractor, Versar, Inc., is organizing, convening, and conducting 
the peer-review workshop. To attend the workshop, register by December 
10, 2009, by calling Versar, Inc. at 703-750-3000, ext. 545, or toll 
free at 1-800-2-VERSAR (ask for Kathy Coon, the cis- and trans-1,2-
Dichloroethylene peer review workshop coordinator), sending a facsimile 
to 703-642-6954 (please reference the ``cis- and trans-1,2-
Dichloroethylene Workshop'' and include your name, title, affiliation, 
full address and contact information), or sending an e-mail to 
kscoon@versar.com (subject line: cis- and trans-1,2-Dichloroethylene 
Peer Review Workshop).
    The draft ``Toxicological Review of cis- and trans-1,2-
Dichloroethylene: In Support of Summary Information on the Integrated 
Risk Information System (IRIS)'' is available primarily via the 
Internet on the National Center for Environmental Assessment's home 
page under the Recent Additions and Publications menus at http://www.epa.gov/ncea. A limited number of paper copies are available from 
the Information Management Team, NCEA; telephone: 703-347-8561; 
facsimile: 703-347-8691. If you are requesting a paper copy, please 
provide your name, mailing address, and the document title, 
``Toxicological Review of cis- and trans-1,2-Dichloroethylene: In 
Support of Summary Information on the Integrated Risk Information 
System (IRIS).'' Copies are not available from Versar, Inc.
    Information on Services for Individuals with Disabilities: EPA 
welcomes public attendance at the ``cis- and trans-1,2-Dichloroethylene 
peer-review workshop'' and will make every effort to accommodate 
persons with disabilities. For information on access or services for 
individuals with disabilities, please contact Versar, Inc. by phone at 
(703) 750-3000, ext. 545, or toll free at 1-800-2-VERSAR (ask for Kathy 
Coon, the cis- and trans-1,2-Dichloroethylene peer review workshop 
coordinator), or by e-mail at kscoon@versar.com (subject line: cis- and 
trans-1,2-Dichloroethylene Peer Review Workshop), preferably at least 
10 days prior to the meeting, to give as much time as possible to 
process your request.

FOR FURTHER INFORMATION CONTACT: Questions regarding information, 
registration, access or services for individuals with disabilities, or 
logistics for the external peer-review workshop should be directed to 
Versar, Inc., 6850 Versar Center, Springfield, VA 22151; telephone: 
703-750-3000, ext. 545, or toll free at 1-800-2-VERSAR (ask for Kathy 
Coon, the cis- and trans-1,2-Dichloroethylene peer review workshop 
coordinator), facsimile: 703-642-6954 (please reference the ``cis- and 
trans-1,2-Dichloroethylene Workshop'' and include your name, title, 
affiliation, full address and contact information), or e-mail: 
kscoon@versar.com (subject line: cis- and trans-1,2-Dichloroethylene 
Peer Review Workshop). To request accommodation of a disability, please 
contact Kathy Coon (at the numbers and e-mail listed above), preferably 
at least 10 days prior to the meeting, to give as much time as possible 
to process your request.
    If you have questions about the document, please contact Audrey 
Galizia, National Center for Environmental Assessment (NCEA), 
telephone: 732-906-6887; facsimile: 732-452-6429; or e-mail 
galizia.audrey@epa.gov.

SUPPLEMENTARY INFORMATION:

Information About IRIS

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at http://www.epa.gov/iris) contains 
qualitative and quantitative health effects information for more than 
540 chemical substances that may be used to support the first two steps 
(hazard identification and dose-response evaluation) of a risk 
assessment process. When supported by available data, the database 
provides oral reference doses (RfDs) and inhalation reference 
concentrations (RfCs) for chronic health effects, and oral slope 
factors and inhalation unit risks for carcinogenic effects. Combined 
with specific exposure information, government and private entities can 
use IRIS data to help characterize public health risks of chemical 
substances in a site-specific situation and thereby

[[Page 58015]]

support risk management decisions designed to protect public health.

    Dated: October 29, 2009.
Rebecca Clark,
Acting Director, National Center for Environmental Assessment.
[FR Doc. E9-27049 Filed 11-9-09; 8:45 am]
BILLING CODE 6560-50-P