National Institute of Mental Health; Notice of Closed Meeting, 56855-56856 [E9-26421]
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Federal Register / Vol. 74, No. 211 / Tuesday, November 3, 2009 / Notices
Office of Inspector General. 2009.
Traceability in the Food Supply Chain.
March 2009. OEI–02–06–00210. Available at
https://oig.hhs.gov/oei/reports/oei-02-0600210.pdf. Accessed and printed July 20,
2009.
Dated: October 29, 2009.
David Horowitz,
Assistant Commissioner for Policy.
[FR Doc. E9–26479 Filed 11–2–09; 8:45 am]
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MSC 7843, Bethesda, MD 20892, 301–594–
6830, gerendad@csr.nih.gov.
This notice is being published less than 15
days prior to the meeting due to the timing
limitations imposed by the review and
funding cycle.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.306, Comparative Medicine;
93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393–93.396, 93.837–93.844,
93.846–93.878, 93.892, 93.893, National
Institutes of Health, HHS)
Dated: October 27, 2009.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. E9–26424 Filed 11–2–09; 8:45 am]
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
56855
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 5858,
MSC 7849, Bethesda, MD 20892, 301–996–
7702, jacobsonrh@csr.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.306, Comparative Medicine;
93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393–93.396, 93.837–93.844,
93.846–93.878, 93.892, 93.893, National
Institutes of Health, HHS)
Dated: October 27, 2009.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. E9–26422 Filed 11–2–09; 8:45 am]
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Center for Scientific Review; Notice of
Closed Meetings
mstockstill on DSKH9S0YB1PROD with NOTICES
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; Brain
Disorders in the Developing World 1.
Date: November 18, 2009.
Time: 3 p.m. to 10 p.m.
Agenda: To review and evaluate grant
applications.
Place: Beacon Hotel and Corporate
Quarters, 1615 Rhode Island Avenue, NW.,
Washington, DC 20036.
Contact Person: Dan D. Gerendasy, PhD,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 5132,
MSC 7843, Bethesda, MD 20892, 301–594–
6830, gerendad@csr.nih.gov.
This notice is being published less than 15
days prior to the meeting due to the timing
limitations imposed by the review and
funding cycle.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; Brain
Disorders in the Developing World 2.
Date: November 19, 2009.
Time: 6 p.m. to 10 p.m.
Agenda: To review and evaluate grant
applications.
Place: Beacon Hotel and Corporate
Quarters, 1615 Rhode Island Avenue, NW.,
Washington, DC 20036.
Contact Person: Dan D. Gerendasy, PhD,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 5132,
VerDate Nov<24>2008
18:15 Nov 02, 2009
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Notice of
Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; Health of
the Population Fellowships.
Date: November 18–19, 2009.
Time: 9 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892
(Virtual Meeting)
Contact Person: Karin F. Helmers, PhD,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Rm. 3166 MSC
7770, Bethesda, MD 20892, 301–435–1017,
helmersk@csr.nih.gov.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; NCRR
Electron Microscopy Resource Review.
Date: November 30–December 2, 2009.
Time: 5 p.m. to 2 p.m.
Agenda: To review and evaluate grant
applications.
Place: Crowne Plaza-Albany City Center,
30 Lodge Street, Albany, NY 12207.
Contact Person: Raymond Jacobson, PhD,
Scientific Review Officer, Center for
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Mental Health;
Notice of Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Mental Health Special Emphasis Panel;
NIMH Brain Bank Resource.
Date: December 2, 2009.
Time: 3 p.m. to 4 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Neuroscience Center, 6001 Executive
Boulevard, Rockville, MD 20852. (Telephone
Conference Call)
Contact Person: Rebecca C Steiner, PhD.,
Scientific Review Officer, Division of
Extramural Activities, National Institute of
Mental Health, NIH, Neuroscience Center,
6001 Executive Blvd, Room 6149, MSC 9608,
Bethesda, MD 20892–9608, 301–443–4525,
steinerr@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.242, Mental Health Research
Grants; 93.281, Scientist Development
Award, Scientist Development Award for
Clinicians, and Research Scientist Award;
93.282, Mental Health National Research
Service Awards for Research Training,
National Institutes of Health, HHS)
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56856
Federal Register / Vol. 74, No. 211 / Tuesday, November 3, 2009 / Notices
Dated: October 27, 2009
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. E9–26421 Filed 11–2–09; 8:45 am]
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In accordance with Section 10(a)(2) of
the Federal Advisory Committee Act
(Pub. L. 92–463), the Centers for Disease
Control and Prevention (CDC)
announces the aforementioned SEP:
mstockstill on DSKH9S0YB1PROD with NOTICES
Time and Date: 12:30 p.m.–4:30 p.m.,
December 1, 2009 (Closed).
Place: Teleconference.
Status: The meeting will be closed to the
public in accordance with provisions set
forth in Section 552b(c) (4) and (6), Title 5
U.S.C., and the Determination of the Director,
Management Analysis and Services Office,
CDC, pursuant to Public Law 92–463.
Matters To Be Discussed: The meeting will
include the initial review, discussion, and
evaluation of applications received in
response to ‘‘CDC Grants for Public Health
Research Dissertation, FOA PAR07–231,
Panel D.’’
Contact Person for More Information:
Maurine Goodman, MA, MPH, Scientific
Review Administrator, CDC, 1600 Clifton
Road, NE., Mailstop D72, Atlanta, GA 30333,
Telephone (404)639–4747.
The Director, Management Analysis and
Services Office, has been delegated the
authority to sign Federal Register notices
pertaining to announcements of meetings and
other committee management activities, for
both CDC and the Agency for Toxic
Substances and Disease Registry.
Dated: October 23, 2009.
Elaine L. Baker,
Director, Management Analysis and Services
Office, Centers for Disease Control and
Prevention.
[FR Doc. E9–26389 Filed 11–2–09; 8:45 am]
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Food and Drug Administration,
HHS.
Disease, Disability, and Injury
Prevention and Control Special
Emphasis Panel (SEP): CDC Grants for
Public Health Research Dissertation
(Panel D), Funding Opportunity
Announcement (FOA) PAR07–231,
Initial Review
18:15 Nov 02, 2009
[Docket No. FDA–2009–N–0519]
AGENCY:
Centers for Disease Control and
Prevention
VerDate Nov<24>2008
Food and Drug Administration
Public Workshop: International
Conference on Harmonisation S2
Genetic Toxicology Issues; Request
for Comments
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
ACTION: Notice of public workshop;
request for comments.
SUMMARY: The Food and Drug
Administration (FDA) is announcing a
public workshop entitled ‘‘ICH S2
Genetic Toxicology Issues.’’ The 1-day
public workshop is intended to seek
constructive input from experts in the
field of genetic toxicology on proposed
changes to the International Conference
on Harmonisation (ICH) guidance
‘‘S2(R1) Genotoxicity Testing and Data
Interpretation for Pharmaceuticals
Intended for Human Use’’ that was
published in March 2008.
DATES: The public workshop will be
held on January 25, 2010, from 8:30 a.m.
to 5 p.m. Register by January 15, 2010,
to make a presentation at the workshop.
See section II in the SUPPLEMENTARY
INFORMATION section for information on
how to attend the workshop. We are
opening a docket to receive your written
or electronic comments. Written or
electronic comments must be submitted
to the docket by February 24, 2010, to
receive consideration.
ADDRESSES: The public workshop will
be held at the Food and Drug
Administration, Center for Drug
Evaluation and Research Advisory
Committee Conference Room, 5630
Fishers Lane, rm. 1066, Rockville, MD
20857. Submit written or electronic
requests to make a presentation to Adele
Seifried (see FOR FURTHER INFORMATION
CONTACT). Submit written comments to
the Division of Dockets Management
(HFA–305), Food and Drug
Administration, 5630 Fishers Lane, rm.
1061, Rockville, MD 20852. Submit
electronic comments to https://
www.regulations.gov. All comments
should be identified with the docket
number found in brackets in the
heading of this document.
FOR FURTHER INFORMATION CONTACT:
Adele Seifried, Center for Drug
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 22, rm. 6482,
Silver Spring, MD 20993–0002, 301–
796–0535, FAX: 301–796–9855, e-mail:
Adele.Seifried@fda.hhs.gov.
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SUPPLEMENTARY INFORMATION:
I. Objectives
The objectives of this workshop are to
provide a scientific forum where experts
in the field of genetic toxicology can
provide their views on proposed
changes to ICH S2(R1). These proposed
changes are described in the following
paragraphs.
A. The Genetox Battery and Followup
Testing: Options 1 and 2
The ICH steering committee agreed
that revision of ICH S2 was appropriate
because the 2 guidances that comprise
it, ICH S2A and ICH S2B, were finalized
nearly 15 years ago and much has been
learned in the interim. ICH S2(R1) is a
draft version that discusses the
components of a basic genetic
toxicology battery as well as in vivo
followup testing that should be
conducted when in vitro tests are
positive. ICH S2(R1) offers two test
options: Option 1 is similar to the
current ICH and CDER test battery with
some modifications. Option 2 removes
the in vitro mammalian cell test from
the test battery and instead includes two
in vivo endpoints that can be assessed
in a single assay. The workshop will
examine these options in addressing
what constitutes an adequate genetic
toxicology battery, including which
tests are reasonable followups to a
positive in vitro cytogenetic assay or
mouse lymphoma assay. The workshop
will also examine the following: (1)
Whether an in vivo comet assay is a
reasonable followup test to a positive in
vitro cytogenetic or mouse lymphoma
assay, and if not, what alternatives exist,
and (2) whether the two-option system
being proposed would provide
comparable or superior patient
protection to the current single-option
test battery.
B. Top Concentration for Mammalian In
Vitro Genotoxicity Assays
The current ICH safety guidances
specify that drug substances should be
tested up to a concentration of 10
millimolars (mM) in vitro if no toxicity
is seen at lower concentrations. The
draft ICH S2(R1) proposes to lower this
top concentration for required testing to
1 mM. This workshop will examine the
scientific basis for this proposal and its
potential effect on patient safety.
II. Attendance and Registration to
Speak
There is no fee to attend the
workshop, and attendees who do not
wish to make a formal presentation to
the scientific panel do not need to
register. Seating will be on a first-come,
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Agencies
[Federal Register Volume 74, Number 211 (Tuesday, November 3, 2009)]
[Notices]
[Pages 56855-56856]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-26421]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institute of Mental Health; Notice of Closed Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is hereby given of the following
meeting.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications, the disclosure of which would
constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: National Institute of Mental Health Special
Emphasis Panel; NIMH Brain Bank Resource.
Date: December 2, 2009.
Time: 3 p.m. to 4 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, Neuroscience Center, 6001
Executive Boulevard, Rockville, MD 20852. (Telephone Conference
Call)
Contact Person: Rebecca C Steiner, PhD., Scientific Review
Officer, Division of Extramural Activities, National Institute of
Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd, Room
6149, MSC 9608, Bethesda, MD 20892-9608, 301-443-4525,
steinerr@mail.nih.gov.
(Catalogue of Federal Domestic Assistance Program Nos. 93.242,
Mental Health Research Grants; 93.281, Scientist Development Award,
Scientist Development Award for Clinicians, and Research Scientist
Award; 93.282, Mental Health National Research Service Awards for
Research Training, National Institutes of Health, HHS)
[[Page 56856]]
Dated: October 27, 2009
Jennifer Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. E9-26421 Filed 11-2-09; 8:45 am]
BILLING CODE 4140-01-P