Draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of the Summary Information in the Integrated Risk Information System (IRIS), 48539-48541 [E9-22912]

Download as PDF Federal Register / Vol. 74, No. 183 / Wednesday, September 23, 2009 / Notices Ethyl Tertiary Butyl Ether assessment, contact Andrew Hotchkiss, IRIS Staff, National Center for Environmental Assessment, U.S. EPA, 109 T.W. Alexander Drive, B243–01, Durham, NC 27711; telephone: 919–541–4164; facsimile: 919–541–0245; or e-mail: hotchkiss.andrew@epa.gov. IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at https://www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 540 chemical substances that may be used to support the first two steps (hazard identification and dose-response evaluation) of a risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with specific exposure information, government and private entities can use IRIS data to help characterize public health risks of chemical substances in a site-specific situation and thereby support risk management decisions designed to protect public health. This listening session is a step in EPA’s revised process, announced on May 21, 2009, for development of human health assessments for inclusion on IRIS. The updated process is posted on the IRIS home page at https:// www.epa.gov/iris. SUPPLEMENTARY INFORMATION: Dated: September 10, 2009. Rebecca Clark, Acting Director, National Center for Environmental Assessment. [FR Doc. E9–22923 Filed 9–22–09; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY mstockstill on DSKH9S0YB1PROD with NOTICES [FRL–8954–9; Docket ID No. EPA–HQ–ORD– 2009–0245] Draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of the Summary Information in the Integrated Risk Information System (IRIS) Environmental Protection Agency (EPA). ACTION: Notice of public comment period and listening session. AGENCY: VerDate Nov<24>2008 17:06 Sep 22, 2009 Jkt 217001 SUMMARY: EPA is announcing a public comment period and a public listening session for the external review draft document titled, ‘‘Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ (EPA/635/R–08/016). The draft document was prepared by the National Center for Environmental Assessment (NCEA) within the EPA’s Office of Research and Development (ORD). The public comment period and the external peer-review workshop, which will be scheduled at a later date and announced in the Federal Register, are separate processes that provide opportunities for all interested parties to comment on the document. EPA intends to forward the public comments that are submitted in accordance with this notice to the external peer-review panel prior to the meeting for their consideration. When finalizing the draft document, EPA intends to consider any public comments that EPA receives in accordance with this notice. EPA is also announcing a listening session to be held on October 27, 2009, during the public comment period for this draft document. This listening session is a step in EPA’s revised IRIS process, announced on May 21, 2009, to develop human health assessments for inclusion in the IRIS database. The purpose of the listening session is to allow all interested parties to present scientific and technical comments on draft IRIS health assessments to EPA and other interested parties during the public comment period and before the external peer review meeting. EPA welcomes the scientific and technical comments that will be provided to the Agency by the listening session participants. The comments will be considered by the Agency as it revises the draft assessment in response to the independent external peer review and the public comments. All presentations will become part of the official public record. EPA is releasing this draft document solely for the purpose of predissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. DATES: The public comment period begins September 23, 2009, and ends November 23, 2009. Technical comments should be in writing and must be received by EPA by November 23, 2009. PO 00000 Frm 00022 Fmt 4703 Sfmt 4703 48539 The listening session on the draft IRIS health assessment for Hydrogen Cyanide and Cyanide Salts will be held on October 27, 2009, beginning at 9 a.m. and ending at 4 p.m., Eastern Daylight Time. If you want to make a presentation at the listening session, you should register by October 20, 2009, indicate that you wish to make oral comments at the session, and indicate the length of your presentation. When you register, please indicate if you will need audio-visual aid (e.g., lap top and slide projector). In general, each presentation should be no more than 30 minutes. If, however, there are more requests for presentations than the allotted time allows, then the time limit for each presentation will be adjusted. A copy of the agenda for the listening session will be available at the meeting. If no speakers have registered by October 20, 2009, the listening session will be cancelled and EPA will notify those registered of the cancellation. Listening session participants who want EPA to share their comments with the external peer reviewers should also submit written comments during the public comment period using the detailed and established procedures described in the SUPPLEMENTARY INFORMATION section of this notice. Comments submitted to the docket prior to the end of the public comment period will be submitted to the external peer reviewers and considered by EPA in the disposition of public comments. All comments must be submitted to the docket, but comments received after the public comment period closes will not be submitted to the external peer reviewers. ADDRESSES: The draft ‘‘Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ is available primarily via the Internet on the NCEA home page under the Recent Additions and Publications menus at https:// www.epa.gov/ncea. A limited number of paper copies are available from the Information Management Team, NCEA; telephone: 703–347–8561; facsimile: 703–347–8691. If you are requesting a paper copy, please provide your name, mailing address, and the document title. Comments may be submitted electronically via https://www.regulations.gov, by mail, by facsimile, or by hand delivery/courier. Please follow the detailed instructions as provided in the SUPPLEMENTARY INFORMATION section of this notice. The listening session on the draft Hydrogen Cyanide and Cyanide Salts assessment will be held at the EPA E:\FR\FM\23SEN1.SGM 23SEN1 mstockstill on DSKH9S0YB1PROD with NOTICES 48540 Federal Register / Vol. 74, No. 183 / Wednesday, September 23, 2009 / Notices offices at Two Potomac Yard (North Building), 7th Floor, Room 7100, 2733 South Crystal Drive, Arlington, Virginia, 22202. To attend the listening session, register by October 20, 2009, via e-mail at saundkat@versar.com (subject line: Hydrogen Cyanide and Cyanide Salts listening session), by phone: 703–750– 3000 extension 545, or by faxing a registration request 703–642–6954 (please reference the ‘‘Hydrogen Cyanide and Cyanide Salts Listening Session’’ and include your name, title, affiliation, full address and contact information). Please note that to gain entrance to this EPA building to attend the meeting, attendees must have photo identification with them and must register at the guard’s desk in the lobby. The guard will retain your photo identification and will provide you with a visitor’s badge. At the guard’s desk, attendees should give the name Christine Ross and the telephone number, 703–347–8592, to the guard on duty. The guard will contact Ms. Ross who will meet you in the reception area to escort you to the meeting room. When you leave the building, please return your visitor’s badge to the guard and you will receive your photo identification. A teleconference line will also be available for registered attendees/ speakers. The teleconference number is 866–299–3188 and the access code is 926–378–7897, followed by the pound sign (#). The teleconference line will be activated at 8:45 a.m., and you will be asked to identify yourself and your affiliation at the beginning of the call. Information on Services for Individuals with Disabilities: EPA welcomes public attendance at the ‘‘Hydrogen Cyanide and Cyanide Salts Listening Session’’ and will make every effort to accommodate persons with disabilities. For information on access or services for individuals with disabilities, please contact Christine Ross at 703–347–8592 or ross.christine@epa.gov. To request accommodation of a disability, please contact Ms. Ross, preferably at least 10 days prior to the meeting, to give EPA as much time as possible to process your request. FOR FURTHER INFORMATION CONTACT: For information on the public comment period, contact the Office of Environmental Information Docket; telephone: 202–566–1752; facsimile: 202–566–1753; or e-mail: ORD.Docket@epa.gov. For information on the public listening sessions, please contact Christine Ross, IRIS Staff, National Center for Environmental Assessment, VerDate Nov<24>2008 17:06 Sep 22, 2009 Jkt 217001 (8601P), U.S. EPA, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone: 703–347–8592; facsimile: 703–347–8689; or e-mail: ross.christine@epa.gov. If you have questions about the document, contact Kathleen Newhouse, National Center for Environmental Assessment (NCEA),1200 Pennsylvania Ave 8601P, Washington DC, 20460; telephone: 703–347–8641; facsimile: 703–347–8689; or e-mail: newhouse.kathleen@epa.gov. SUPPLEMENTARY INFORMATION: I. Information About IRIS IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at https://www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 540 chemical substances that may be used to support the first two steps (hazard identification and doseresponse evaluation) of a risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with specific exposure information, government and private entities can use IRIS data to help characterize public health risks of chemical substances in a site-specific situation and thereby support risk management decisions designed to protect public health. II. How to Submit Technical Comments to the Docket at https:// www.regulations.gov Submit your comments, identified by Docket ID No. EPA–HQ–ORD–2009– 0245 by one of the following methods: • https://www.regulations.gov: Follow the on-line instructions for submitting comments. • E-mail: ORD.Docket@epa.gov. • Fax: 202–566–1753. • Mail: Office of Environmental Information (OEI) Docket (Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202–566–1752. • Hand Delivery: The OEI Docket is located in the EPA Headquarters Docket Center, EPA West Building, Room 3334, 1301 Constitution Ave., NW., Washington, DC. The EPA Docket Center’s Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday PO 00000 Frm 00023 Fmt 4703 Sfmt 4703 through Friday, excluding legal holidays. The telephone number for the Public Reading Room is 202–566–1744. Such deliveries are only accepted during the docket’s normal hours of operation, and special arrangements should be made for deliveries of boxed information. If you provide comments by mail or hand delivery, please submit one unbound original with pages numbered consecutively, and three copies of the comments. For attachments, provide an index, number pages consecutively with the comments, and submit an unbound original and three copies. Instructions: Direct your comments to Docket ID No. EPA–HQ–ORD–2009– 0245. Please ensure that your comments are submitted within the specified comment period. Comments received after the closing date will be marked ‘‘late,’’ and may only be considered if time permits. It is EPA’s policy to include all comments it receives in the public docket without change and to make the comments available online at https://www.regulations.gov, including any personal information provided, unless a comment includes information claimed to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through https://www.regulations.gov or e-mail. The https://www.regulations.gov Web site is an ‘‘anonymous access’’ system, which means EPA will not know your identity or contact information unless you provide it in the body of your comment. If you send an e-mail comment directly to EPA without going through https://www.regulations.gov, your e-mail address will be automatically captured and included as part of the comment that is placed in the public docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CD–ROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form of encryption, and be free of any defects or viruses. For additional information about EPA’s public docket visit the EPA Docket Center homepage at https://www.epa.gov/epahome/ dockets.htm. Docket: All documents in the docket are listed in the E:\FR\FM\23SEN1.SGM 23SEN1 Federal Register / Vol. 74, No. 183 / Wednesday, September 23, 2009 / Notices https://www.regulations.gov index. Although listed in the index, some information is not publicly available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other material, such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in https://www.regulations.gov or in hard copy at the OEI Docket in the EPA Headquarters Docket Center. Dated: August 21, 2009. Rebecca Clark, Acting Director, National Center for Environmental Assessment. [FR Doc. E9–22912 Filed 9–22–09; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY [EPA–HQ–OW–2009–0297; FRL–8961–8] RIN 2040–AF08 Drinking Water: Perchlorate Supplemental Request for Comments mstockstill on DSKH9S0YB1PROD with NOTICES AGENCY: Environmental Protection Agency (EPA). ACTION: Reopening of public comment period. SUMMARY: In an August 19, 2009, Federal Register notice, EPA announced that it was seeking comments on additional approaches to analyzing data related to the Agency’s preliminary regulatory determination for perchlorate. The additional comments are sought in an effort to ensure consideration of all the potential options for evaluating whether there is a meaningful opportunity for human health risk reduction of perchlorate through a national primary drinking water rule. In response to requests from several stakeholders, this action reopens the public comment period for an additional 15 days. DATES: EPA must receive your comments on or before October 8, 2009. ADDRESSES: Submit your comments, identified by Docket ID No. EPA–HQ– OW–2009–0297, by one of the following methods: • https://www.regulations.gov: Follow the on-line instructions for submitting comments. • Mail: Water Docket, Environmental Protection Agency, Mailcode: 2822T, 1200 Pennsylvania Ave., NW., Washington, DC 20460. • Hand Delivery: Water Docket, EPA Docket Center (EPA/DC) EPA West, Room 3334, 1301 Constitution Ave., VerDate Nov<24>2008 17:06 Sep 22, 2009 Jkt 217001 NW., Washington, DC. Such deliveries are only accepted during the Docket’s normal hours of operation, and special arrangements should be made for deliveries of boxed information. Instructions: Direct your comments to Docket ID No. EPA–HQ–OW–2009– 0297. EPA’s policy is that all comments received will be included in the public docket without change and may be made available online at https:// www.regulations.gov, including any personal information provided, unless the comment includes information claimed to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through https:// www.regulations.gov or e-mail. The https://www.regulations.gov Web site is an ‘‘anonymous access’’ system, which means EPA will not know your identity or contact information unless you provide it in the body of your comment. If you send an e-mail comment directly to EPA without going through https:// www.regulations.gov your e-mail address will be automatically captured and included as part of the comment that is placed in the public docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CD–ROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form of encryption, and be free of any defects or viruses. FOR FURTHER INFORMATION CONTACT: Eric Burneson, Office of Ground Water and Drinking Water, Standards and Risk Management Division, at (202) 564– 5250 or e-mail burneson.eric@epa.gov. For general information contact the EPA Safe Drinking Water Hotline at (800) 426–4791 or e-mail: hotlinesdwa@epa.gov. SUPPLEMENTARY INFORMATION: Background The statutory and regulatory background is described in detail in the October 10, 2008, Federal Register notice of a preliminary regulatory determination for perchlorate (73 FR 60262) and summarized in the August 19, 2009, Federal Register notice of supplemental request for comments (74 FR 41883). Briefly, the Safe Drinking Water Act (SDWA) section 1412, as PO 00000 Frm 00024 Fmt 4703 Sfmt 4703 48541 amended in 1996, requires EPA to make a determination whether to regulate at least 5 contaminants from its contaminant candidate list (CCL) every 5 years. To regulate a contaminant in drinking water, EPA must determine that it meets three criteria: (1) The contaminant may have an adverse effect on human health, (2) the contaminant is known to occur or there is a substantial likelihood that the contaminant will occur in public water systems with a frequency and at levels of public health concern, and (3) regulation of such contaminant presents a meaningful opportunity for health risk reduction for persons served by public water systems. On October 10, 2008, EPA published a preliminary regulatory determination for perchlorate, requesting public comment on its determination that perchlorate did not meet the second and third criteria for regulation. On November 12, 2008, EPA published a Federal Register Notice (73 FR 66895) reopening the comment period for the preliminary regulatory determination for an additional 15 days. The Agency received 32,795 comment letters on the preliminary regulatory determination for perchlorate. These comments and other supporting materials for the October 10, 2008, notice are available electronically at https:// www.regulations.gov (Docket ID No. EPA–HQ–OW–2008–0692). On August 19, 2009, EPA published a Federal Register notice of supplemental request for comment on a broader range of alternatives for interpreting the available data on: the level of health concern, the frequency of occurrence of perchlorate in drinking water, and the opportunity for health risk reduction through a national primary drinking water standard. These alternative interpretations may impact the Agency’s final regulatory determination for perchlorate. The supporting materials for the August 19, 2009, supplemental notice are available electronically at https://www.regulations.gov (Docket ID No. EPA–HQ–OW–2009–0297). Next Steps Several stakeholders have requested an extension to the September 18, 2009, comment deadline specified in the August 19, 2009, supplemental notice in order to evaluate EPA’s alternative analyses and prepare comments. This action reopens the comment period for an additional 15 days. The Agency will consider the information and comments submitted in response to the August 19, 2009, supplemental notice until October 8, 2009. EPA will also consider the comments received on the previous E:\FR\FM\23SEN1.SGM 23SEN1

Agencies

[Federal Register Volume 74, Number 183 (Wednesday, September 23, 2009)]
[Notices]
[Pages 48539-48541]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-22912]


-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

[FRL-8954-9; Docket ID No. EPA-HQ-ORD-2009-0245]


Draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts: 
In Support of the Summary Information in the Integrated Risk 
Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of public comment period and listening session.

-----------------------------------------------------------------------

SUMMARY: EPA is announcing a public comment period and a public 
listening session for the external review draft document titled, 
``Toxicological Review of Hydrogen Cyanide and Cyanide Salts: In 
Support of Summary Information on the Integrated Risk Information 
System (IRIS)'' (EPA/635/R-08/016). The draft document was prepared by 
the National Center for Environmental Assessment (NCEA) within the 
EPA's Office of Research and Development (ORD). The public comment 
period and the external peer-review workshop, which will be scheduled 
at a later date and announced in the Federal Register, are separate 
processes that provide opportunities for all interested parties to 
comment on the document. EPA intends to forward the public comments 
that are submitted in accordance with this notice to the external peer-
review panel prior to the meeting for their consideration. When 
finalizing the draft document, EPA intends to consider any public 
comments that EPA receives in accordance with this notice.
    EPA is also announcing a listening session to be held on October 
27, 2009, during the public comment period for this draft document. 
This listening session is a step in EPA's revised IRIS process, 
announced on May 21, 2009, to develop human health assessments for 
inclusion in the IRIS database. The purpose of the listening session is 
to allow all interested parties to present scientific and technical 
comments on draft IRIS health assessments to EPA and other interested 
parties during the public comment period and before the external peer 
review meeting. EPA welcomes the scientific and technical comments that 
will be provided to the Agency by the listening session participants. 
The comments will be considered by the Agency as it revises the draft 
assessment in response to the independent external peer review and the 
public comments. All presentations will become part of the official 
public record.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination.

DATES: The public comment period begins September 23, 2009, and ends 
November 23, 2009. Technical comments should be in writing and must be 
received by EPA by November 23, 2009.
    The listening session on the draft IRIS health assessment for 
Hydrogen Cyanide and Cyanide Salts will be held on October 27, 2009, 
beginning at 9 a.m. and ending at 4 p.m., Eastern Daylight Time. If you 
want to make a presentation at the listening session, you should 
register by October 20, 2009, indicate that you wish to make oral 
comments at the session, and indicate the length of your presentation. 
When you register, please indicate if you will need audio-visual aid 
(e.g., lap top and slide projector). In general, each presentation 
should be no more than 30 minutes. If, however, there are more requests 
for presentations than the allotted time allows, then the time limit 
for each presentation will be adjusted. A copy of the agenda for the 
listening session will be available at the meeting. If no speakers have 
registered by October 20, 2009, the listening session will be cancelled 
and EPA will notify those registered of the cancellation.
    Listening session participants who want EPA to share their comments 
with the external peer reviewers should also submit written comments 
during the public comment period using the detailed and established 
procedures described in the SUPPLEMENTARY INFORMATION section of this 
notice. Comments submitted to the docket prior to the end of the public 
comment period will be submitted to the external peer reviewers and 
considered by EPA in the disposition of public comments. All comments 
must be submitted to the docket, but comments received after the public 
comment period closes will not be submitted to the external peer 
reviewers.

ADDRESSES: The draft ``Toxicological Review of Hydrogen Cyanide and 
Cyanide Salts: In Support of Summary Information on the Integrated Risk 
Information System (IRIS)'' is available primarily via the Internet on 
the NCEA home page under the Recent Additions and Publications menus at 
https://www.epa.gov/ncea. A limited number of paper copies are available 
from the Information Management Team, NCEA; telephone: 703-347-8561; 
facsimile: 703-347-8691. If you are requesting a paper copy, please 
provide your name, mailing address, and the document title.
    Comments may be submitted electronically via https://www.regulations.gov, by mail, by facsimile, or by hand delivery/
courier. Please follow the detailed instructions as provided in the 
SUPPLEMENTARY INFORMATION section of this notice.
    The listening session on the draft Hydrogen Cyanide and Cyanide 
Salts assessment will be held at the EPA

[[Page 48540]]

offices at Two Potomac Yard (North Building), 7th Floor, Room 7100, 
2733 South Crystal Drive, Arlington, Virginia, 22202. To attend the 
listening session, register by October 20, 2009, via e-mail at 
saundkat@versar.com (subject line: Hydrogen Cyanide and Cyanide Salts 
listening session), by phone: 703-750-3000 extension 545, or by faxing 
a registration request 703-642-6954 (please reference the ``Hydrogen 
Cyanide and Cyanide Salts Listening Session'' and include your name, 
title, affiliation, full address and contact information). Please note 
that to gain entrance to this EPA building to attend the meeting, 
attendees must have photo identification with them and must register at 
the guard's desk in the lobby. The guard will retain your photo 
identification and will provide you with a visitor's badge. At the 
guard's desk, attendees should give the name Christine Ross and the 
telephone number, 703-347-8592, to the guard on duty. The guard will 
contact Ms. Ross who will meet you in the reception area to escort you 
to the meeting room. When you leave the building, please return your 
visitor's badge to the guard and you will receive your photo 
identification.
    A teleconference line will also be available for registered 
attendees/speakers. The teleconference number is 866-299-3188 and the 
access code is 926-378-7897, followed by the pound sign (). 
The teleconference line will be activated at 8:45 a.m., and you will be 
asked to identify yourself and your affiliation at the beginning of the 
call.
    Information on Services for Individuals with Disabilities: EPA 
welcomes public attendance at the ``Hydrogen Cyanide and Cyanide Salts 
Listening Session'' and will make every effort to accommodate persons 
with disabilities. For information on access or services for 
individuals with disabilities, please contact Christine Ross at 703-
347-8592 or ross.christine@epa.gov. To request accommodation of a 
disability, please contact Ms. Ross, preferably at least 10 days prior 
to the meeting, to give EPA as much time as possible to process your 
request.

FOR FURTHER INFORMATION CONTACT: For information on the public comment 
period, contact the Office of Environmental Information Docket; 
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail: 
ORD.Docket@epa.gov.
    For information on the public listening sessions, please contact 
Christine Ross, IRIS Staff, National Center for Environmental 
Assessment, (8601P), U.S. EPA, 1200 Pennsylvania Avenue, NW., 
Washington, DC 20460; telephone: 703-347-8592; facsimile: 703-347-8689; 
or e-mail: ross.christine@epa.gov.
    If you have questions about the document, contact Kathleen 
Newhouse, National Center for Environmental Assessment (NCEA),1200 
Pennsylvania Ave 8601P, Washington DC, 20460; telephone: 703-347-8641; 
facsimile: 703-347-8689; or e-mail: newhouse.kathleen@epa.gov.

SUPPLEMENTARY INFORMATION: 

I. Information About IRIS

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at https://www.epa.gov/iris) contains 
qualitative and quantitative health effects information for more than 
540 chemical substances that may be used to support the first two steps 
(hazard identification and dose-response evaluation) of a risk 
assessment process. When supported by available data, the database 
provides oral reference doses (RfDs) and inhalation reference 
concentrations (RfCs) for chronic health effects, and oral slope 
factors and inhalation unit risks for carcinogenic effects. Combined 
with specific exposure information, government and private entities can 
use IRIS data to help characterize public health risks of chemical 
substances in a site-specific situation and thereby support risk 
management decisions designed to protect public health.

II. How to Submit Technical Comments to the Docket at https://www.regulations.gov

    Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2009-
0245 by one of the following methods:
     https://www.regulations.gov: Follow the on-line 
instructions for submitting comments.
     E-mail: ORD.Docket@epa.gov.
     Fax: 202-566-1753.
     Mail: Office of Environmental Information (OEI) Docket 
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
     Hand Delivery: The OEI Docket is located in the EPA 
Headquarters Docket Center, EPA West Building, Room 3334, 1301 
Constitution Ave., NW., Washington, DC. The EPA Docket Center's Public 
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the Public 
Reading Room is 202-566-1744. Such deliveries are only accepted during 
the docket's normal hours of operation, and special arrangements should 
be made for deliveries of boxed information. If you provide comments by 
mail or hand delivery, please submit one unbound original with pages 
numbered consecutively, and three copies of the comments. For 
attachments, provide an index, number pages consecutively with the 
comments, and submit an unbound original and three copies.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2009-0245. Please ensure that your comments are submitted within the 
specified comment period. Comments received after the closing date will 
be marked ``late,'' and may only be considered if time permits. It is 
EPA's policy to include all comments it receives in the public docket 
without change and to make the comments available online at https://www.regulations.gov, including any personal information provided, 
unless a comment includes information claimed to be Confidential 
Business Information (CBI) or other information whose disclosure is 
restricted by statute. Do not submit information that you consider to 
be CBI or otherwise protected through https://www.regulations.gov or e-
mail. The https://www.regulations.gov Web site is an ``anonymous 
access'' system, which means EPA will not know your identity or contact 
information unless you provide it in the body of your comment. If you 
send an e-mail comment directly to EPA without going through https://www.regulations.gov, your e-mail address will be automatically captured 
and included as part of the comment that is placed in the public docket 
and made available on the Internet. If you submit an electronic 
comment, EPA recommends that you include your name and other contact 
information in the body of your comment and with any disk or CD-ROM you 
submit. If EPA cannot read your comment due to technical difficulties 
and cannot contact you for clarification, EPA may not be able to 
consider your comment. Electronic files should avoid the use of special 
characters, any form of encryption, and be free of any defects or 
viruses. For additional information about EPA's public docket visit the 
EPA Docket Center homepage at https://www.epa.gov/epahome/dockets.htm.
    Docket: All documents in the docket are listed in the

[[Page 48541]]

https://www.regulations.gov index. Although listed in the index, some 
information is not publicly available, e.g., CBI or other information 
whose disclosure is restricted by statute. Certain other material, such 
as copyrighted material, will be publicly available only in hard copy. 
Publicly available docket materials are available either electronically 
in https://www.regulations.gov or in hard copy at the OEI Docket in the 
EPA Headquarters Docket Center.

    Dated: August 21, 2009.
Rebecca Clark,
Acting Director, National Center for Environmental Assessment.
[FR Doc. E9-22912 Filed 9-22-09; 8:45 am]
BILLING CODE 6560-50-P
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