Tembotrione; Pesticide Tolerances, 47891-47894 [E9-22519]
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Federal Register / Vol. 74, No. 180 / Friday, September 18, 2009 / Rules and Regulations
• Is not a significant regulatory action
subject to Executive Order 13211 (66 FR
28355, May 22, 2001);
• Is not subject to requirements of
Section 12(d) of the National
Technology Transfer and Advancement
Act of 1995 (15 U.S.C. 272 note) because
application of those requirements would
be inconsistent with the Clean Air Act;
and
• Does not provide EPA with the
discretionary authority to address, as
appropriate, disproportionate human
health or environmental effects, using
practicable and legally permissible
methods, under Executive Order 12898
(59 FR 7629, February 16, 1994).
In addition, this rule does not have
Tribal implications as specified by
Executive Order 13175 (65 FR 67249,
November 9, 2000), because the SIP is
not approved to apply in Indian country
located in the State, and EPA notes that
it will not impose substantial direct
costs on Tribal governments or preempt
Tribal law.
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B. Submission to Congress and the
Comptroller General
The Congressional Review Act, 5
U.S.C. 801 et seq., as added by the Small
Business Regulatory Enforcement
Fairness Act of 1996, generally provides
that before a rule may take effect, the
agency promulgating the rule must
submit a rule report, which includes a
copy of the rule, to each House of the
Congress and to the Comptroller General
of the United States. EPA will submit a
report containing this action and other
required information to the U.S. Senate,
the U.S. House of Representatives, and
the Comptroller General of the United
States prior to publication of the rule in
the Federal Register. A major rule
cannot take effect until 60 days after it
is published in the Federal Register.
This action is not a ‘‘major rule’’ as
defined by 5 U.S.C. 804(2).
C. Petitions for Judicial Review
Under section 307(b)(1) of the Clean
Air Act, petitions for judicial review of
this action must be filed in the United
States Court of Appeals for the
appropriate circuit by November 17,
2009. Filing a petition for
reconsideration by the Administrator of
this final rule does not affect the finality
of this action for the purposes of judicial
review nor does it extend the time
within which a petition for judicial
review may be filed, and shall not
postpone the effectiveness of such rule
or action. Parties with objections to this
direct final rule are encouraged to file a
comment in response to the parallel
notice of proposed rulemaking for this
action published in the proposed rules
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section of today’s Federal Register,
rather than file an immediate petition
for judicial review of this direct final
rule, so that EPA can withdraw this
direct final rule and address the
comment in the proposed rulemaking.
This action may not be challenged later
in proceedings to enforce its
requirements. (See section 307(b)(2).)
47891
The revised Denver Emergency
Episode Plan, adopted by the State of
Colorado February 28, 1996, was
submitted by the Governor of Colorado
with a September 16, 1997 letter.
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requests for hearings must be received
on or before November 17, 2009, and
must be filed in accordance with the
instructions provided in 40 CFR part
178 (see also Unit I.C. of the
SUPPLEMENTARY INFORMATION).
ADDRESSES: EPA has established a
docket for this action under docket
identification (ID) number EPA–HQ–
OPP–2008–0813. All documents in the
docket are listed in the docket index
available at https://www.regulations.gov.
Although listed in the index, some
information is not publicly available,
e.g., Confidential Business Information
(CBI) or other information whose
disclosure is restricted by statute.
Certain other material, such as
copyrighted material, is not placed on
the Internet and will be publicly
available only in hard copy form.
Publicly available docket materials are
available in the electronic docket at
https://www.regulations.gov, or, if only
available in hard copy, at the OPP
Regulatory Public Docket in Rm. S–
4400, One Potomac Yard (South Bldg.),
2777 S. Crystal Dr., Arlington, VA. The
Docket Facility is open from 8:30 a.m.
to 4 p.m., Monday through Friday,
excluding legal holidays. The Docket
Facility telephone number is (703) 305–
5805.
FOR FURTHER INFORMATION CONTACT:
Joanne Miller, Registration Division
(7505P), Office of Pesticide Programs,
Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington,
DC 20460–0001; telephone number:
(703) 305–6224; e-mail address:
miller.joanne@epa.gov.
[FR Doc. E9–22279 Filed 9–17–09; 8:45 am]
SUPPLEMENTARY INFORMATION:
BILLING CODE 6560–50–P
I. General Information
List of Subjects in 40 CFR Part 52
Environmental protection, Air
pollution control, Incorporation by
reference, Intergovernmental relations,
Nitrogen dioxide, Ozone, Particulate
matter, Reporting and recordkeeping
requirements, Volatile Organic
Compounds.
Dated: September 4, 2009.
Carol Rushin,
Acting Regional Administrator, Region 8.
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40 CFR part 52 is amended as follows:
PART 52—[AMENDED]
1. The authority citation for Part 52
continues to read as follows:
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Authority: 42 U.S.C. 7401 et seq.
Subpart G—Colorado
2. Section 52.321 is amended by
revising the introductory text to read as
follows:
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§ 52.321
Classification of regions.
A. Does this Action Apply to Me?
ENVIRONMENTAL PROTECTION
AGENCY
40 CFR Part 180
[EPA–HQ–OPP–2008–0813; FRL–8431–5]
Tembotrione; Pesticide Tolerances
AGENCY: Environmental Protection
Agency (EPA).
ACTION: Final rule.
SUMMARY: This regulation revises the
tolerances for residues of the herbicide
tembotrione, including its metabolites
and degradates, in or on corn, sweet
forage; corn, sweet, stover; and corn,
sweet, kernel plus cob with husks
removed. Bayer CropScience requested
these tolerances under the Federal Food,
Drug, and Cosmetic Act (FFDCA).
DATES: This regulation is effective
September 18, 2009. Objections and
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You may be potentially affected by
this action if you are an agricultural
producer, food manufacturer, or
pesticide manufacturer. Potentially
affected entities may include, but are
not limited to those engaged in the
following activities:
• Crop production (NAICS code 111).
• Animal production (NAICS code
112).
• Food manufacturing (NAICS code
311).
• Pesticide manufacturing (NAICS
code 32532).
This listing is not intended to be
exhaustive, but rather to provide a guide
for readers regarding entities likely to be
affected by this action. Other types of
entities not listed in this unit could also
be affected. The North American
Industrial Classification System
(NAICS) codes have been provided to
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Federal Register / Vol. 74, No. 180 / Friday, September 18, 2009 / Rules and Regulations
assist you and others in determining
whether this action might apply to
certain entities. If you have any
questions regarding the applicability of
this action to a particular entity, consult
the person listed under FOR FURTHER
INFORMATION CONTACT.
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B. How Can I Access Electronic Copies
of this Document?
In addition to accessing electronically
available documents at https://
www.regulations.gov, you may access
this Federal Register document
electronically through the EPA Internet
under the ‘‘Federal Register’’ listings at
https://www.epa.gov/fedrgstr. You may
also access a frequently updated
electronic version of EPA’s tolerance
regulations at 40 CFR part 180 through
the Government Printing Office’s e-CFR
cite at https://www.gpoaccess.gov/ecfr.
C. Can I File an Objection or Hearing
Request?
Under section 408(g) of FFDCA, 21
U.S.C. 346a, any person may file an
objection to any aspect of this regulation
and may also request a hearing on those
objections. You must file your objection
or request a hearing on this regulation
in accordance with the instructions
provided in 40 CFR part 178. To ensure
proper receipt by EPA, you must
identify docket ID number EPA–HQ–
OPP–2008–0813 in the subject line on
the first page of your submission. All
requests must be in writing, and must be
mailed or delivered to the Hearing Clerk
as required by 40 CFR part 178 on or
before November 17, 2009.
In addition to filing an objection or
hearing request with the Hearing Clerk
as described in 40 CFR part 178, please
submit a copy of the filing that does not
contain any CBI for inclusion in the
public docket that is described in
ADDRESSES. Information not marked
confidential pursuant to 40 CFR part 2
may be disclosed publicly by EPA
without prior notice. Submit this copy,
identified by docket ID number EPA–
HQ–OPP–2008–0813, by one of the
following methods:
• Federal eRulemaking Portal: https://
www.regulations.gov. Follow the on-line
instructions for submitting comments.
• Mail: Office of Pesticide Programs
(OPP) Regulatory Public Docket (7502P),
Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington,
DC 20460–0001.
• Delivery: OPP Regulatory Public
Docket (7502P), Environmental
Protection Agency, Rm. S–4400, One
Potomac Yard (South Bldg.), 2777 S.
Crystal Dr., Arlington, VA. Deliveries
are only accepted during the Docket
Facility’s normal hours of operation
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(8:30 a.m. to 4 p.m., Monday through
Friday, excluding legal holidays).
Special arrangements should be made
for deliveries of boxed information. The
Docket Facility telephone number is
(703) 305–5805.
II. Petition for Tolerance
In the Federal Register of December 3,
2008 (73 FR 73651) (FRL–8391–3), EPA
issued a notice pursuant to section
408(d)(3) of FFDCA, 21 U.S.C.
346a(d)(3), announcing the filing of a
pesticide petition (PP 8F7452) by Bayer
CropScience, 2 T.W. Alexander Drive,
Research Triangle Park, NC 27709. The
petition requested that 40 CFR 180.634
be amended by revising tolerances for
combined residues of the herbicide
tembotrione and its metabolites in or on
corn, sweet, kernel plus cob with husks
removed from 0.04 to 0.01 parts per
million (ppm); corn, sweet, forage from
1.0 ppm to 0.09 ppm; and corn, sweet,
stover from 1.2 ppm to 0.15 ppm. That
notice referenced a summary of the
petition prepared by Bayer CropScience,
the registrant, which is available to the
public in the docket, https://
www.regulations.gov. There were no
comments received in response to the
notice of filing.
Based upon review of the data
supporting the petition, EPA has
determined that the proposed tolerances
should be revised as follows: corn,
sweet, forage at 0.35 ppm; corn, sweet,
stover at 0.60 ppm. EPA has also
determined that the tolerance for corn,
sweet, kernel plus cob with husks
removed is acceptable at the proposed
level of 0.01 ppm but that compliance
with the tolerance level is to be
determined by measuring only parent
tembotrione. The reasons for these
changes are explained in Unit IV.C.
III. Aggregate Risk Assessment and
Determination of Safety
Section 408(b)(2)(A)(i) of FFDCA
allows EPA to establish a tolerance (the
legal limit for a pesticide chemical
residue in or on a food) only if EPA
determines that the tolerance is ‘‘safe.’’
Section 408(b)(2)(A)(ii) of FFDCA
defines ‘‘safe’’ to mean that ‘‘there is a
reasonable certainty that no harm will
result from aggregate exposure to the
pesticide chemical residue, including
all anticipated dietary exposures and all
other exposures for which there is
reliable information.’’ This includes
exposure through drinking water and in
residential settings, but does not include
occupational exposure. Section
408(b)(2)(C) of FFDCA requires EPA to
give special consideration to exposure
of infants and children to the pesticide
chemical residue in establishing a
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tolerance and to ‘‘ensure that there is a
reasonable certainty that no harm will
result to infants and children from
aggregate exposure to the pesticide
chemical residue. . . .’’
Consistent with section 408(b)(2)(D)
of FFDCA, and the factors specified in
section 408(b)(2)(D) of FFDCA, EPA has
reviewed the available scientific data
and other relevant information in
support of this action. EPA has
sufficient data to assess the hazards of
and to make a determination on
aggregate exposure for the petitioned-for
tolerances for residues of the herbicide
tembotrione and its metabolites and
degradates, in or on corn, sweet, kernel
plus cob with husks removed at 0.01
ppm; corn, sweet, forage at 0.35 ppm;
and corn, sweet, stover at 0.60 ppm.
EPA’s assessment of exposures and risks
associated with establishing tolerances
follows.
In the Federal Register of September
28, 2007 (72 FR 55078) (FRL–8148–2)
the Agency published a final rule
establishing tolerances for combined
residues of tembotrione and its M5
metabolite in or on corn, sweet, kernel
plus cob with husks removed at 0.04
ppm; corn, sweet, forage at 1.0 ppm; and
corn, sweet stover at 1.2 ppm. When the
Agency conducted the risk assessment
in support of the September 2007
tolerance action, it considered the use of
tembotrione on corn (field and sweet),
incorporating potential residues of
tembotrione and its metabolites in or on
corn commodities and secondary
residues of tembotrione in livestock
commodities from consumption of
treated feedstuffs, including corn forage.
Residues of tembotrione on corn and
livestock commodities were assumed to
be present at tolerance levels. Since EPA
considered the residues of tembotrione
on corn, sweet, kernel plus cob with
husks removed; corn, sweet, forage; and
corn, sweet, stover at a higher level in
its most recent risk assessments,
reducing the tolerances on sweet corn
commodities will reduce the estimated
aggregate exposures resulting from use
of tembotrione. While it is true that
lowering the tolerances will reduce the
estimated exposure to tembotrione,
changes have occurred in toxicology
data requirements for pesticides since
the 2007 risk assessment was completed
which could impact the Food Quality
Protection Act (FQPA) safety factor (SF)
for tembotrione, currently retained at
10X for acute and chronic dietary risk
assessment. EPA’s assessment of the
new data requirements as they relate to
the FQPA safety factor for tembotrione
is discussed below.
EPA began requiring acute and
subchronic neurotoxicity testing and
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functional immunotoxicity testing of all
food and non-food use pesticides on
December 26, 2007 (40 CFR part 158
subpart F). Acute and subchronic
neurotoxicity studies in rats, as well as
a developmental neurotoxicity (DNT)
study in rats are available for
tembotrione and were considered by
EPA in its 2007 aggregate risk
assessment and FQPA safety factor
determination. Immunotoxicity data are
not available for tembotrione. In the
absence of specific immunotoxicity
studies, EPA has evaluated the available
tembotrione toxicity data to determine
whether an additional database
uncertainty factor is needed to account
for potential immunotoxicity. The
decreased absolute and relative thymus
weights observed in female rats in the
subchronic oral toxicity study were not
corroborated with histopathological
changes, and there were no thymus
effects in other subchronic, chronic and
carcinogenicity studies in rats.
Therefore, the thymus weight changes
in this study are spurious effects and
not indicative of immunotoxicity. The
increased incidence of minimal
extramedullary hematopoeisis of the
spleen in the rat offspring of the
reproduction toxicity study and the
anemia seen in the mice in the
carcinogenicity study are indicators of
toxicity to the hematopoietic system and
not indicators of frank immunotoxicity.
No other effects on organs of the
immune system were seen, and the
toxicity profile clearly indicates the eye,
liver and kidneys to be the target organs
for tembotrione-induced toxicity.
Additionally, tembotrione does not
belong to a class of chemicals (e.g., the
organotins, heavy metals, or
halogenated aromatic hydrocarbons)
that would be expected to be
immunotoxic in laboratory animals.
Therefore, the Agency does not believe
that conducting immunotoxicity testing
will result in doses lower than those
currently used for overall risk
assessments (0.8 milligrams/kilograms/
day (mg/kg/day) for acute and 0.04 mg/
kg/day for repeated exposures) and an
additional uncertainty factor is not
needed to account for potential
immunotoxicity. Based on these
considerations, EPA concludes that no
uncertainty factors are required in
addition to those used in the 2007 risk
assessment for tembotrione.
Therefore, based on the risk
assessments discussed in the final rule
published in the Federal Register of
September 28, 2007, EPA concludes that
there is a reasonable certainty that no
harm will result to the general
population, or to infants and children
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from aggregate exposure to tembotrione
residues.
IV. Other Considerations
A. Analytical Enforcement Methodology
An Adequate enforcement
methodology, liquid chromatography/
mass spectroscopy (LC/MS/MS) method
is available to enforce the tolerance
expression. The method may be
requested from: Chief, Analytical
Chemistry Branch, Environmental
Science Center, 701 Mapes Rd., Ft.
Meade, MD 20755–5350; telephone
number (410) 305–905; e-mail address:
residuemethods@epa.gov.
B. International Residue Limits
There is neither a Codex proposal, nor
Canadian or Mexican limits for residues
of tembotrione and its metabolites in or
on crops or livestock commodities.
C. Revisions to Petitioned-For
Tolerances
The submitted data support the
following revised tolerances for residues
of tembotrione in or on sweet corn
commodities: Corn, sweet, kernel plus
cob with husks removed at 0.01 ppm;
corn, sweet, forage at 0.35 ppm; corn,
sweet, stover at 0.60 ppm. EPA revised
the tolerance levels for corn, sweet,
forage and stover from those proposed
by the registrant based on analyses of
the residue field trial data using the
Agency’s Tolerance Spreadsheet in
accordance with the Agency’s Guidance
for Setting Pesticide Tolerances Based
on Field Trial Data. There were no
detectable residues of tembotrione in
corn, sweet, kernel plus cob with husks
removed; and metabolism data for
tembotrione show that while M5 is a
major metabolite in forage and stover, it
was present at less then 1% of the Total
Radioactive Residue (TRR) in corn
grain. Based on the results of these field
trial and metabolism studies, the
tolerance for corn, sweet, kernel plus
cob with husks removed is being
established at the limit of quantitation
(0.01 ppm) for tembotrione.
Tolerances for tembotrione are
currently expressed in terms of ‘‘2-[2chloro-4-(methylsulfonyl)-3-[(2,2,2trifluoroethoxy)methyl]benzoyl]-1,3cyclohexanedione, and its metabolite, 2[2-chloro-4-(methylsulfonyl)-3-[(2,2,2trifluoroethoxy)methyl]benzoyl]-4,6dihydroxy-1,3-cyclohexanedione.’’ EPA
is revising the tolerance expression for
existing tolerances and the new
tolerances on sweet corn commodities
to clarify the chemical moieties that are
covered by the tolerances and specify
how compliance with the tolerances is
to be measured. The revised tolerance
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expression makes clear that the
tolerances cover ‘‘residues of
tembotrione, including its metabolites
and degradates,’’ and that compliance
with the tolerance levels for all
commodities except corn, sweet, kernel
plus cob with husks removed, will be
determined by measuring only the sum
of tembotrione, 2-[2-chloro-4(methylsulfonyl)-3-[(2,2,2trifluoroethoxy)methyl]benzoyl]-1,3cyclohexanedione and its metabolite, 2[2-chloro-4-(methylsulfonyl)-3-[(2,2,2trifluoroethoxy) methyl]benzoyl]-4,6dihydroxy-1,3-cyclohexanedione,
calculated as the stoichiometric
equivalent of tembotrione. Compliance
with the tolerance level for corn, sweet,
kernel plus cob with husks removed
will be determined by measuring only
tembotrione.
EPA has determined that it is
reasonable to make this change final
without prior proposal and opportunity
for comment, because public comment
is not necessary, in that the change has
no substantive effect on the tolerances,
but rather is merely intended to clarify
the existing tolerance expression.
V. Conclusion
Therefore, tolerances are revised for
residues of the herbicide tembotrione,
including its metabolites and
degradates, in or on corn, sweet, kernel
plus cob with husks removed at 0.01
ppm; corn, sweet, forage at 0.35 ppm;
and corn, sweet, stover at 0.60 ppm.
Compliance with the tolerance levels
specified for corn, sweet, forage and
stover is to be determined by measuring
only the sum of tembotrione, 2-[2chloro-4-(methylsulfonyl)-3-[(2,2,2trifluoroethoxy)methyl]benzoyl]-1,3cyclohexanedione and its metabolite, 2[2-chloro-4-(methylsulfonyl)-3-[(2,2,2trifluoroethoxy) methyl]benzoyl]-4,6dihydroxy-1,3-cyclohexanedione,
calculated as the stoichiometric
equivalent of tembotrione, in or on the
commodities. Compliance with
tolerance level for corn, sweet, kernel
plus cob with husks removed, will be
determined by measuring only
tembotrione.
VI. Statutory and Executive Order
Reviews
This final rule establishes tolerances
under section 408(d) of FFDCA in
response to a petition submitted to the
Agency. The Office of Management and
Budget (OMB) has exempted these types
of actions from review under Executive
Order 12866, entitled Regulatory
Planning and Review (58 FR 51735,
October 4, 1993). Because this final rule
has been exempted from review under
Executive Order 12866, this final rule is
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not subject to Executive Order 13211,
entitled Actions Concerning Regulations
That Significantly Affect Energy Supply,
Distribution, or Use (66 FR 28355, May
22, 2001) or Executive Order 13045,
entitled Protection of Children from
Environmental Health Risks and Safety
Risks (62 FR 19885, April 23, 1997).
This final rule does not contain any
information collections subject to OMB
approval under the Paperwork
Reduction Act (PRA), 44 U.S.C. 3501 et
seq., nor does it require any special
considerations under Executive Order
12898, entitled Federal Actions to
Address Environmental Justice in
Minority Populations and Low-Income
Populations (59 FR 7629, February 16,
1994).
Since tolerances and exemptions that
are established on the basis of a petition
under section 408(d) of FFDCA, such as
the tolerance in this final rule, do not
require the issuance of a proposed rule,
the requirements of the Regulatory
Flexibility Act (RFA) (5 U.S.C. 601 et
seq.) do not apply.
This final rule directly regulates
growers, food processors, food handlers,
and food retailers, not States or tribes,
nor does this action alter the
relationships or distribution of power
and responsibilities established by
Congress in the preemption provisions
of section 408(n)(4) of FFDCA. As such,
the Agency has determined that this
action will not have a substantial direct
effect on States or tribal governments,
on the relationship between the national
government and the States or tribal
governments, or on the distribution of
power and responsibilities among the
various levels of government or between
the Federal Government and Indian
tribes. Thus, the Agency has determined
that Executive Order 13132, entitled
Federalism (64 FR 43255, August 10,
1999) and Executive Order 13175,
entitled Consultation and Coordination
with Indian Tribal Governments (65 FR
67249, November 9, 2000) do not apply
to this final rule. In addition, this final
rule does not impose any enforceable
duty or contain any unfunded mandate
as described under Title II of the
Unfunded Mandates Reform Act of 1995
(UMRA) (Public Law 104–4).
This action does not involve any
technical standards that would require
Agency consideration of voluntary
consensus standards pursuant to section
12(d) of the National Technology
Transfer and Advancement Act of 1995
(NTTAA), Public Law 104–113, section
12(d) (15 U.S.C. 272 note).
VII. Congressional Review Act
The Congressional Review Act, 5
U.S.C. 801 et seq., generally provides
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that before a rule may take effect, the
agency promulgating the rule must
submit a rule report to each House of
the Congress and to the Comptroller
General of the United States. EPA will
submit a report containing this rule and
other required information to the U.S.
Senate, the U.S. House of
Representatives, and the Comptroller
General of the United States prior to
publication of this final rule in the
Federal Register. This final rule is not
a ‘‘major rule’’ as defined by 5 U.S.C.
804(2).
List of Subjects in 40 CFR Part 180
Environmental protection,
Administrative practice and procedure,
Agricultural commodities, Pesticides
and pests, Reporting and recordkeeping
requirements.
Dated: September 8, 2009.
Lois Rossi,
Director, Registration Division, Office of
Pesticide Programs.
Therefore, 40 CFR chapter I is
amended as follows:
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Commodity
Parts per million
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*
Corn, sweet, forage
Corn, sweet, stover
*
*
*
........
........
*
*
*
0.35
0.60
*
*
(2) Tolerances are established for
residues of the herbicide tembotrione,
including its metabolites and
degradates, in or on the commodities
listed in the table to this paragraph.
Compliance with the tolerance levels
specified below is to be determined by
measuring only tembotrione, 2-[2chloro-4-(methylsulfonyl)-3-[(2,2,2trifluoroethoxy)methyl]benzoyl]-1,3cyclohexanedione in or on the following
commodities.
Commodity
Parts per million
Corn, sweet, kernel plus
cob with husks removed .........................
*
*
*
*
0.01
*
[FR Doc. E9–22519 Filed 9–17–09; 8:45 am]
BILLING CODE 6560–50–S
PART 180—[AMENDED]
1. The authority citation for part 180
continues to read as follows:
■
Authority: 21 U.S.C. 321(q), 346a and 371.
2. Section 180.634 is amended as
follows:
a. By revising the introductory text of
paragraph (a) and redesignating it as
paragraph (a)(1).
b. In the table to newly redesignated
paragraph (a)(1) by revising the entries
for corn, sweet, forage, and corn, sweet,
stover, and by removing the entry for
corn, sweet, kernel plus cob with husks
removed.
c. By adding paragraph (a)(2).
The revised and added text reads as
follows:
■
§ 180.634 Tembotrione; tolerances for
residues.
(a) * * * (1) Tolerances are established
for residues of the herbicide
tembotrione, including its metabolites
and degradates, in or on the
commodities listed in the table to this
paragraph. Compliance with the
tolerance levels specified below is to be
determined by measuring only the sum
of tembotrione, 2-[2-chloro-4(methylsulfonyl)-3-[(2,2,2trifluoroethoxy)methyl]benzoyl]-1,3cyclohexanedione and its metabolite, 2[2-chloro-4-(methylsulfonyl)-3-[(2,2,2trifluoroethoxy) methyl]benzoyl]-4,6dihydroxy-1,3-cyclohexanedione,
calculated as the stoichiometric
equivalent of tembotrione, in or on the
following commodities.
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FEDERAL COMMUNICATIONS
COMMISSION
47 CFR Part 64
[CG Docket 03–123 and WC Docket No. 05–
196; DA 09–1323]
Telecommunications Relay Services
and Speech-to-Speech Services for
Individuals With Hearing and Speech
Disabilities; E911 Requirements for IPEnabled Service Providers
AGENCY: Federal Communications
Commission.
ACTION: Final rule; extension of
deadline.
SUMMARY: In this document, the
Commission via the Consumer and
Governmental Affairs Bureau (Bureau)
extends the registration deadline
established in the Telecommunications
Relay Services and Speech-to-Speech
Services for Individuals with Hearing
and Speech Disabilities; E911
Requirements for IP-Enabled Service
Providers, Second Report and Order and
Order on Reconsideration (Second
Internet-based TRS Order), during
which Internet-based
Telecommunications Relay Service
(TRS) providers may continue to
complete the non-emergency calls of
unregistered users. This action is
necessary because extending the
deadline will ensure a more orderly
transition to ten-digit numbering for
E:\FR\FM\18SER1.SGM
18SER1
Agencies
[Federal Register Volume 74, Number 180 (Friday, September 18, 2009)]
[Rules and Regulations]
[Pages 47891-47894]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-22519]
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ENVIRONMENTAL PROTECTION AGENCY
40 CFR Part 180
[EPA-HQ-OPP-2008-0813; FRL-8431-5]
Tembotrione; Pesticide Tolerances
AGENCY: Environmental Protection Agency (EPA).
ACTION: Final rule.
-----------------------------------------------------------------------
SUMMARY: This regulation revises the tolerances for residues of the
herbicide tembotrione, including its metabolites and degradates, in or
on corn, sweet forage; corn, sweet, stover; and corn, sweet, kernel
plus cob with husks removed. Bayer CropScience requested these
tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA).
DATES: This regulation is effective September 18, 2009. Objections and
requests for hearings must be received on or before November 17, 2009,
and must be filed in accordance with the instructions provided in 40
CFR part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION).
ADDRESSES: EPA has established a docket for this action under docket
identification (ID) number EPA-HQ-OPP-2008-0813. All documents in the
docket are listed in the docket index available at https://www.regulations.gov. Although listed in the index, some information is
not publicly available, e.g., Confidential Business Information (CBI)
or other information whose disclosure is restricted by statute. Certain
other material, such as copyrighted material, is not placed on the
Internet and will be publicly available only in hard copy form.
Publicly available docket materials are available in the electronic
docket at https://www.regulations.gov, or, if only available in hard
copy, at the OPP Regulatory Public Docket in Rm. S-4400, One Potomac
Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. The Docket
Facility is open from 8:30 a.m. to 4 p.m., Monday through Friday,
excluding legal holidays. The Docket Facility telephone number is (703)
305-5805.
FOR FURTHER INFORMATION CONTACT: Joanne Miller, Registration Division
(7505P), Office of Pesticide Programs, Environmental Protection Agency,
1200 Pennsylvania Ave., NW., Washington, DC 20460-0001; telephone
number: (703) 305-6224; e-mail address: miller.joanne@epa.gov.
SUPPLEMENTARY INFORMATION:
I. General Information
A. Does this Action Apply to Me?
You may be potentially affected by this action if you are an
agricultural producer, food manufacturer, or pesticide manufacturer.
Potentially affected entities may include, but are not limited to those
engaged in the following activities:
Crop production (NAICS code 111).
Animal production (NAICS code 112).
Food manufacturing (NAICS code 311).
Pesticide manufacturing (NAICS code 32532).
This listing is not intended to be exhaustive, but rather to
provide a guide for readers regarding entities likely to be affected by
this action. Other types of entities not listed in this unit could also
be affected. The North American Industrial Classification System
(NAICS) codes have been provided to
[[Page 47892]]
assist you and others in determining whether this action might apply to
certain entities. If you have any questions regarding the applicability
of this action to a particular entity, consult the person listed under
FOR FURTHER INFORMATION CONTACT.
B. How Can I Access Electronic Copies of this Document?
In addition to accessing electronically available documents at
https://www.regulations.gov, you may access this Federal Register
document electronically through the EPA Internet under the ``Federal
Register'' listings at https://www.epa.gov/fedrgstr. You may also access
a frequently updated electronic version of EPA's tolerance regulations
at 40 CFR part 180 through the Government Printing Office's e-CFR cite
at https://www.gpoaccess.gov/ecfr.
C. Can I File an Objection or Hearing Request?
Under section 408(g) of FFDCA, 21 U.S.C. 346a, any person may file
an objection to any aspect of this regulation and may also request a
hearing on those objections. You must file your objection or request a
hearing on this regulation in accordance with the instructions provided
in 40 CFR part 178. To ensure proper receipt by EPA, you must identify
docket ID number EPA-HQ-OPP-2008-0813 in the subject line on the first
page of your submission. All requests must be in writing, and must be
mailed or delivered to the Hearing Clerk as required by 40 CFR part 178
on or before November 17, 2009.
In addition to filing an objection or hearing request with the
Hearing Clerk as described in 40 CFR part 178, please submit a copy of
the filing that does not contain any CBI for inclusion in the public
docket that is described in ADDRESSES. Information not marked
confidential pursuant to 40 CFR part 2 may be disclosed publicly by EPA
without prior notice. Submit this copy, identified by docket ID number
EPA-HQ-OPP-2008-0813, by one of the following methods:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the on-line instructions for submitting comments.
Mail: Office of Pesticide Programs (OPP) Regulatory Public
Docket (7502P), Environmental Protection Agency, 1200 Pennsylvania
Ave., NW., Washington, DC 20460-0001.
Delivery: OPP Regulatory Public Docket (7502P),
Environmental Protection Agency, Rm. S-4400, One Potomac Yard (South
Bldg.), 2777 S. Crystal Dr., Arlington, VA. Deliveries are only
accepted during the Docket Facility's normal hours of operation (8:30
a.m. to 4 p.m., Monday through Friday, excluding legal holidays).
Special arrangements should be made for deliveries of boxed
information. The Docket Facility telephone number is (703) 305-5805.
II. Petition for Tolerance
In the Federal Register of December 3, 2008 (73 FR 73651) (FRL-
8391-3), EPA issued a notice pursuant to section 408(d)(3) of FFDCA, 21
U.S.C. 346a(d)(3), announcing the filing of a pesticide petition (PP
8F7452) by Bayer CropScience, 2 T.W. Alexander Drive, Research Triangle
Park, NC 27709. The petition requested that 40 CFR 180.634 be amended
by revising tolerances for combined residues of the herbicide
tembotrione and its metabolites in or on corn, sweet, kernel plus cob
with husks removed from 0.04 to 0.01 parts per million (ppm); corn,
sweet, forage from 1.0 ppm to 0.09 ppm; and corn, sweet, stover from
1.2 ppm to 0.15 ppm. That notice referenced a summary of the petition
prepared by Bayer CropScience, the registrant, which is available to
the public in the docket, https://www.regulations.gov. There were no
comments received in response to the notice of filing.
Based upon review of the data supporting the petition, EPA has
determined that the proposed tolerances should be revised as follows:
corn, sweet, forage at 0.35 ppm; corn, sweet, stover at 0.60 ppm. EPA
has also determined that the tolerance for corn, sweet, kernel plus cob
with husks removed is acceptable at the proposed level of 0.01 ppm but
that compliance with the tolerance level is to be determined by
measuring only parent tembotrione. The reasons for these changes are
explained in Unit IV.C.
III. Aggregate Risk Assessment and Determination of Safety
Section 408(b)(2)(A)(i) of FFDCA allows EPA to establish a
tolerance (the legal limit for a pesticide chemical residue in or on a
food) only if EPA determines that the tolerance is ``safe.'' Section
408(b)(2)(A)(ii) of FFDCA defines ``safe'' to mean that ``there is a
reasonable certainty that no harm will result from aggregate exposure
to the pesticide chemical residue, including all anticipated dietary
exposures and all other exposures for which there is reliable
information.'' This includes exposure through drinking water and in
residential settings, but does not include occupational exposure.
Section 408(b)(2)(C) of FFDCA requires EPA to give special
consideration to exposure of infants and children to the pesticide
chemical residue in establishing a tolerance and to ``ensure that there
is a reasonable certainty that no harm will result to infants and
children from aggregate exposure to the pesticide chemical residue. . .
.''
Consistent with section 408(b)(2)(D) of FFDCA, and the factors
specified in section 408(b)(2)(D) of FFDCA, EPA has reviewed the
available scientific data and other relevant information in support of
this action. EPA has sufficient data to assess the hazards of and to
make a determination on aggregate exposure for the petitioned-for
tolerances for residues of the herbicide tembotrione and its
metabolites and degradates, in or on corn, sweet, kernel plus cob with
husks removed at 0.01 ppm; corn, sweet, forage at 0.35 ppm; and corn,
sweet, stover at 0.60 ppm. EPA's assessment of exposures and risks
associated with establishing tolerances follows.
In the Federal Register of September 28, 2007 (72 FR 55078) (FRL-
8148-2) the Agency published a final rule establishing tolerances for
combined residues of tembotrione and its M5 metabolite in or on corn,
sweet, kernel plus cob with husks removed at 0.04 ppm; corn, sweet,
forage at 1.0 ppm; and corn, sweet stover at 1.2 ppm. When the Agency
conducted the risk assessment in support of the September 2007
tolerance action, it considered the use of tembotrione on corn (field
and sweet), incorporating potential residues of tembotrione and its
metabolites in or on corn commodities and secondary residues of
tembotrione in livestock commodities from consumption of treated
feedstuffs, including corn forage. Residues of tembotrione on corn and
livestock commodities were assumed to be present at tolerance levels.
Since EPA considered the residues of tembotrione on corn, sweet, kernel
plus cob with husks removed; corn, sweet, forage; and corn, sweet,
stover at a higher level in its most recent risk assessments, reducing
the tolerances on sweet corn commodities will reduce the estimated
aggregate exposures resulting from use of tembotrione. While it is true
that lowering the tolerances will reduce the estimated exposure to
tembotrione, changes have occurred in toxicology data requirements for
pesticides since the 2007 risk assessment was completed which could
impact the Food Quality Protection Act (FQPA) safety factor (SF) for
tembotrione, currently retained at 10X for acute and chronic dietary
risk assessment. EPA's assessment of the new data requirements as they
relate to the FQPA safety factor for tembotrione is discussed below.
EPA began requiring acute and subchronic neurotoxicity testing and
[[Page 47893]]
functional immunotoxicity testing of all food and non-food use
pesticides on December 26, 2007 (40 CFR part 158 subpart F). Acute and
subchronic neurotoxicity studies in rats, as well as a developmental
neurotoxicity (DNT) study in rats are available for tembotrione and
were considered by EPA in its 2007 aggregate risk assessment and FQPA
safety factor determination. Immunotoxicity data are not available for
tembotrione. In the absence of specific immunotoxicity studies, EPA has
evaluated the available tembotrione toxicity data to determine whether
an additional database uncertainty factor is needed to account for
potential immunotoxicity. The decreased absolute and relative thymus
weights observed in female rats in the subchronic oral toxicity study
were not corroborated with histopathological changes, and there were no
thymus effects in other subchronic, chronic and carcinogenicity studies
in rats. Therefore, the thymus weight changes in this study are
spurious effects and not indicative of immunotoxicity. The increased
incidence of minimal extramedullary hematopoeisis of the spleen in the
rat offspring of the reproduction toxicity study and the anemia seen in
the mice in the carcinogenicity study are indicators of toxicity to the
hematopoietic system and not indicators of frank immunotoxicity. No
other effects on organs of the immune system were seen, and the
toxicity profile clearly indicates the eye, liver and kidneys to be the
target organs for tembotrione-induced toxicity. Additionally,
tembotrione does not belong to a class of chemicals (e.g., the
organotins, heavy metals, or halogenated aromatic hydrocarbons) that
would be expected to be immunotoxic in laboratory animals. Therefore,
the Agency does not believe that conducting immunotoxicity testing will
result in doses lower than those currently used for overall risk
assessments (0.8 milligrams/kilograms/day (mg/kg/day) for acute and
0.04 mg/kg/day for repeated exposures) and an additional uncertainty
factor is not needed to account for potential immunotoxicity. Based on
these considerations, EPA concludes that no uncertainty factors are
required in addition to those used in the 2007 risk assessment for
tembotrione.
Therefore, based on the risk assessments discussed in the final
rule published in the Federal Register of September 28, 2007, EPA
concludes that there is a reasonable certainty that no harm will result
to the general population, or to infants and children from aggregate
exposure to tembotrione residues.
IV. Other Considerations
A. Analytical Enforcement Methodology
An Adequate enforcement methodology, liquid chromatography/mass
spectroscopy (LC/MS/MS) method is available to enforce the tolerance
expression. The method may be requested from: Chief, Analytical
Chemistry Branch, Environmental Science Center, 701 Mapes Rd., Ft.
Meade, MD 20755-5350; telephone number (410) 305-905; e-mail address:
residuemethods@epa.gov.
B. International Residue Limits
There is neither a Codex proposal, nor Canadian or Mexican limits
for residues of tembotrione and its metabolites in or on crops or
livestock commodities.
C. Revisions to Petitioned-For Tolerances
The submitted data support the following revised tolerances for
residues of tembotrione in or on sweet corn commodities: Corn, sweet,
kernel plus cob with husks removed at 0.01 ppm; corn, sweet, forage at
0.35 ppm; corn, sweet, stover at 0.60 ppm. EPA revised the tolerance
levels for corn, sweet, forage and stover from those proposed by the
registrant based on analyses of the residue field trial data using the
Agency's Tolerance Spreadsheet in accordance with the Agency's Guidance
for Setting Pesticide Tolerances Based on Field Trial Data. There were
no detectable residues of tembotrione in corn, sweet, kernel plus cob
with husks removed; and metabolism data for tembotrione show that while
M5 is a major metabolite in forage and stover, it was present at less
then 1% of the Total Radioactive Residue (TRR) in corn grain. Based on
the results of these field trial and metabolism studies, the tolerance
for corn, sweet, kernel plus cob with husks removed is being
established at the limit of quantitation (0.01 ppm) for tembotrione.
Tolerances for tembotrione are currently expressed in terms of ``2-
[2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoyl]-
1,3-cyclohexanedione, and its metabolite, 2-[2-chloro-4-
(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoyl]-4,6-
dihydroxy-1,3-cyclohexanedione.'' EPA is revising the tolerance
expression for existing tolerances and the new tolerances on sweet corn
commodities to clarify the chemical moieties that are covered by the
tolerances and specify how compliance with the tolerances is to be
measured. The revised tolerance expression makes clear that the
tolerances cover ``residues of tembotrione, including its metabolites
and degradates,'' and that compliance with the tolerance levels for all
commodities except corn, sweet, kernel plus cob with husks removed,
will be determined by measuring only the sum of tembotrione, 2-[2-
chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoyl]-
1,3-cyclohexanedione and its metabolite, 2-[2-chloro-4-
(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl]-4,6-
dihydroxy-1,3-cyclohexanedione, calculated as the stoichiometric
equivalent of tembotrione. Compliance with the tolerance level for
corn, sweet, kernel plus cob with husks removed will be determined by
measuring only tembotrione.
EPA has determined that it is reasonable to make this change final
without prior proposal and opportunity for comment, because public
comment is not necessary, in that the change has no substantive effect
on the tolerances, but rather is merely intended to clarify the
existing tolerance expression.
V. Conclusion
Therefore, tolerances are revised for residues of the herbicide
tembotrione, including its metabolites and degradates, in or on corn,
sweet, kernel plus cob with husks removed at 0.01 ppm; corn, sweet,
forage at 0.35 ppm; and corn, sweet, stover at 0.60 ppm. Compliance
with the tolerance levels specified for corn, sweet, forage and stover
is to be determined by measuring only the sum of tembotrione, 2-[2-
chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoyl]-
1,3-cyclohexanedione and its metabolite, 2-[2-chloro-4-
(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl]-4,6-
dihydroxy-1,3-cyclohexanedione, calculated as the stoichiometric
equivalent of tembotrione, in or on the commodities. Compliance with
tolerance level for corn, sweet, kernel plus cob with husks removed,
will be determined by measuring only tembotrione.
VI. Statutory and Executive Order Reviews
This final rule establishes tolerances under section 408(d) of
FFDCA in response to a petition submitted to the Agency. The Office of
Management and Budget (OMB) has exempted these types of actions from
review under Executive Order 12866, entitled Regulatory Planning and
Review (58 FR 51735, October 4, 1993). Because this final rule has been
exempted from review under Executive Order 12866, this final rule is
[[Page 47894]]
not subject to Executive Order 13211, entitled Actions Concerning
Regulations That Significantly Affect Energy Supply, Distribution, or
Use (66 FR 28355, May 22, 2001) or Executive Order 13045, entitled
Protection of Children from Environmental Health Risks and Safety Risks
(62 FR 19885, April 23, 1997). This final rule does not contain any
information collections subject to OMB approval under the Paperwork
Reduction Act (PRA), 44 U.S.C. 3501 et seq., nor does it require any
special considerations under Executive Order 12898, entitled Federal
Actions to Address Environmental Justice in Minority Populations and
Low-Income Populations (59 FR 7629, February 16, 1994).
Since tolerances and exemptions that are established on the basis
of a petition under section 408(d) of FFDCA, such as the tolerance in
this final rule, do not require the issuance of a proposed rule, the
requirements of the Regulatory Flexibility Act (RFA) (5 U.S.C. 601 et
seq.) do not apply.
This final rule directly regulates growers, food processors, food
handlers, and food retailers, not States or tribes, nor does this
action alter the relationships or distribution of power and
responsibilities established by Congress in the preemption provisions
of section 408(n)(4) of FFDCA. As such, the Agency has determined that
this action will not have a substantial direct effect on States or
tribal governments, on the relationship between the national government
and the States or tribal governments, or on the distribution of power
and responsibilities among the various levels of government or between
the Federal Government and Indian tribes. Thus, the Agency has
determined that Executive Order 13132, entitled Federalism (64 FR
43255, August 10, 1999) and Executive Order 13175, entitled
Consultation and Coordination with Indian Tribal Governments (65 FR
67249, November 9, 2000) do not apply to this final rule. In addition,
this final rule does not impose any enforceable duty or contain any
unfunded mandate as described under Title II of the Unfunded Mandates
Reform Act of 1995 (UMRA) (Public Law 104-4).
This action does not involve any technical standards that would
require Agency consideration of voluntary consensus standards pursuant
to section 12(d) of the National Technology Transfer and Advancement
Act of 1995 (NTTAA), Public Law 104-113, section 12(d) (15 U.S.C. 272
note).
VII. Congressional Review Act
The Congressional Review Act, 5 U.S.C. 801 et seq., generally
provides that before a rule may take effect, the agency promulgating
the rule must submit a rule report to each House of the Congress and to
the Comptroller General of the United States. EPA will submit a report
containing this rule and other required information to the U.S. Senate,
the U.S. House of Representatives, and the Comptroller General of the
United States prior to publication of this final rule in the Federal
Register. This final rule is not a ``major rule'' as defined by 5
U.S.C. 804(2).
List of Subjects in 40 CFR Part 180
Environmental protection, Administrative practice and procedure,
Agricultural commodities, Pesticides and pests, Reporting and
recordkeeping requirements.
Dated: September 8, 2009.
Lois Rossi,
Director, Registration Division, Office of Pesticide Programs.
0
Therefore, 40 CFR chapter I is amended as follows:
PART 180--[AMENDED]
0
1. The authority citation for part 180 continues to read as follows:
Authority: 21 U.S.C. 321(q), 346a and 371.
0
2. Section 180.634 is amended as follows:
a. By revising the introductory text of paragraph (a) and
redesignating it as paragraph (a)(1).
b. In the table to newly redesignated paragraph (a)(1) by revising
the entries for corn, sweet, forage, and corn, sweet, stover, and by
removing the entry for corn, sweet, kernel plus cob with husks removed.
c. By adding paragraph (a)(2).
The revised and added text reads as follows:
Sec. 180.634 Tembotrione; tolerances for residues.
(a) * * * (1) Tolerances are established for residues of the
herbicide tembotrione, including its metabolites and degradates, in or
on the commodities listed in the table to this paragraph. Compliance
with the tolerance levels specified below is to be determined by
measuring only the sum of tembotrione, 2-[2-chloro-4-(methylsulfonyl)-
3-[(2,2,2-trifluoroethoxy)methyl]benzoyl]-1,3-cyclohexanedione and its
metabolite, 2-[2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)
methyl]benzoyl]-4,6-dihydroxy-1,3-cyclohexanedione, calculated as the
stoichiometric equivalent of tembotrione, in or on the following
commodities.
------------------------------------------------------------------------
Commodity Parts per million
------------------------------------------------------------------------
* * * * *
Corn, sweet, forage.................................. 0.35
Corn, sweet, stover.................................. 0.60
* * * * *
------------------------------------------------------------------------
(2) Tolerances are established for residues of the herbicide
tembotrione, including its metabolites and degradates, in or on the
commodities listed in the table to this paragraph. Compliance with the
tolerance levels specified below is to be determined by measuring only
tembotrione, 2-[2-chloro-4-(methylsulfonyl)-3-[(2,2,2-
trifluoroethoxy)methyl]benzoyl]-1,3-cyclohexanedione in or on the
following commodities.
------------------------------------------------------------------------
Commodity Parts per million
------------------------------------------------------------------------
Corn, sweet, kernel plus cob with husks removed...... 0.01
------------------------------------------------------------------------
* * * * *
[FR Doc. E9-22519 Filed 9-17-09; 8:45 am]
BILLING CODE 6560-50-S