Availability of Draft Toxicological Profile for Perfluoroalkyls, 36492-36493 [E9-17529]
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36492
Federal Register / Vol. 74, No. 140 / Thursday, July 23, 2009 / Notices
social networking sites (without
parental consent) for surveys. The
Academy for Educational Development
will be conducting the research. There
is no cost to respondents other than
their time. The total estimated annual
burden hours are 481.
ESTIMATED ANNUALIZED BURDEN HOURS
Number of
respondents
Type of respondent
Form name
Parents of 15–17 yr old ..................................
Females (15–17 yr old) ...................................
Female (18–25 yr old) ....................................
Female (15–25 yr old) ....................................
Female (15–25 yr old) ....................................
Focus Group Screener for Parents of Minors
Focus Group Screener for Minors .................
Focus Group Screener for Adult Women ......
Focus Group Moderator Guide (15–25) ........
Mall Intercept Screener & Moderator Guide
(15–25).
Online Screener and Survey (15–25) ............
Female (15–25 yr old) ....................................
Dated: July 16, 2009.
Marilyn S. Radke,
Reports Clearance Officer, Centers for Disease
Control and Prevention.
[FR Doc. E9–17525 Filed 7–22–09; 8:45 am]
BILLING CODE 4163–18–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Agency for Toxic Substances and
Disease Registry
[ATSDR–253]
Availability of Draft Toxicological
Profile for Perfluoroalkyls
erowe on DSK5CLS3C1PROD with NOTICES
AGENCY: Agency for Toxic Substances
and Disease Registry (ATSDR),
Department of Health and Human
Services (HHS).
ACTION: Notice of availability.
SUMMARY: This notice announces the
availability of the draft toxicological
profile for perfluoroalkyls, prepared by
ATSDR, for review and comment.
DATES: In order to be considered,
comments on this draft toxicological
profile must be received on or before
October 30, 2009. Comments received
after the public comment period will be
considered at the discretion of ATSDR
on the basis of what is deemed to be in
the best interest of the general public.
ADDRESSES: Requests for a printed copy
of the draft toxicological profile should
be sent to the attention of Ms. Olga
Dawkins, Division of Toxicology and
Environmental Medicine, Agency for
Toxic Substances and Disease Registry,
Mailstop F–32, 1600 Clifton Road, NE.,
Atlanta, Georgia 30333. Electronic
access to the document is also available
at the ATSDR Web site: https://
www.atsdr.cdc.gov/toxpro2.html.
Requests for printed copies of the
draft toxicological profile must be in
writing and must specifically identify
VerDate Nov<24>2008
15:01 Jul 22, 2009
Jkt 217001
the toxicological profile that you wish to
receive. ATSDR reserves the right to
provide free of charge only one copy of
each profile requested. In case of
extended distribution delays, requestors
will be notified.
Comments regarding the draft
toxicological profile for perfluoroalkyls
should be sent to the attention of Ms.
Nickolette Roney, Division of
Toxicology and Environmental
Medicine, Agency for Toxic Substances
and Disease Registry, Mailstop F–62,
1600 Clifton Road, NE., Atlanta, Georgia
30333. Electronic comments may be
sent to TPPublicComments@cdc.gov. All
comments sent electronically should
contain the docket control number
ATSDR–253 in the subject line.
Written comments and other data
submitted in response to this notice and
the draft toxicological profile should
bear the docket control number ATSDR–
253. Send one copy of all comments and
three copies of all supporting
documents to Ms. Roney at the above
address by the end of the comment
period. Because all public comments
regarding ATSDR toxicological profiles
are available for public inspection, no
confidential information should be
submitted in response to this notice.
FOR FURTHER INFORMATION CONTACT: Ms.
Olga Dawkins, Division of Toxicology
and Environmental Medicine, Agency
for Toxic Substances and Disease
Registry, Mailstop F–62, 1600 Clifton
Road, NE., Atlanta, Georgia 30333;
telephone number (800) 232–4636 or
(770) 488–3315.
SUPPLEMENTARY INFORMATION: This draft
toxicological profile for perfluoroalkyls
was prepared in accordance with
guidelines developed by the Agency for
Toxic Substances and Disease Registry
and the Environmental Protection
Agency (EPA) for the preparation of
toxicological profiles. The original
guidelines were published in the
Federal Register on April 17, 1987.
PO 00000
Frm 00045
Fmt 4703
Sfmt 4703
Number
of responses
per
respondent
Average
burden per
response
(in hours)
54
54
126
180
200
1
1
1
1
1
5/60
5/60
5/60
2
10/60
500
1
8/60
While perfluoroalkyls are not found on
the ATSDR Priority List of Hazardous
Substances, ATSDR has determined that
a profile for these substances was
necessary because data indicate that
some perfluoroalkyls are found in the
blood of the United States general
population and in the environment. The
agency also determined that it was
important to characterize the current
available information regarding the
health effects from exposure to
perfluoroalkyls in order to support and
inform public health responses and
activities by ATSDR and others. This
profile will be revised and republished
as necessary.
Section 104(i)(3) of the
Comprehensive Environmental
Response, Compensation, and Liability
Act [42 U.S.C. 9604(i)(3)] outlines the
content of the toxicological profiles.
Each profile includes an examination, a
summary, and an interpretation of
available toxicological information and
epidemiologic evaluations. This
information and these data are to be
used to identify the levels of significant
human exposure to a substance and the
associated health effects. The profiles
must also include a determination of
whether adequate information on the
health effects of each substance is
available or in the process of
development. When adequate
information is not available, ATSDR, in
cooperation with the National
Toxicology Program (NTP), will initiate
a research program to determine these
health effects.
Although key studies for this
substance were considered during the
profile development process, this
Federal Register notice solicits any
additional studies, particularly
unpublished data and ongoing studies,
which will be evaluated for possible
addition to the profile now or in the
future.
E:\FR\FM\23JYN1.SGM
23JYN1
36493
Federal Register / Vol. 74, No. 140 / Thursday, July 23, 2009 / Notices
The following draft toxicological
profile will be made available to the
public on or about July 6, 2009.
Document
Toxicological profile
CAS No.
1 .................................................................
PERFLUOROALKYLS ..................................................................................................
000375–22–4
000335–67–1
001763–23–1
All profiles issued as ‘‘Draft for Public
Comment’’ represent ATSDR’s best
efforts to provide important
toxicological information on priority
substances. We are seeking public
comments and additional information
that may be used to supplement this
profile. ATSDR remains committed to
providing a public comment period for
these documents as the best means to
serve public health and our clients.
Ken Rose,
Director, Office of Policy, Planning, and
Evaluation, National Center for
Environmental Health/Agency for Toxic
Substances and Disease Registry.
[FR Doc. E9–17529 Filed 7–22–09; 8:45 am]
BILLING CODE 4163–70–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Agency for Toxic Substances and
Disease Registry
[ATSDR–254]
Notice of Development of Set 23
Toxicological Profiles
AGENCY: Agency for Toxic Substances
and Disease Registry (ATSDR),
Department of Health and Human
Services (HHS).
ACTION: Notice.
consists of three new drafts and two
updated drafts. These profiles will be
available to the public on or about
October 17, 2009. Electronic access to
these documents will be available at the
ATSDR Web site: https://
www.atsdr.cdc.gov/toxpro2.html.
Set 23 Toxicological Profiles
The following toxicological profiles
are now being developed:
SUMMARY: This notice announces the
development of Set 23 Toxicological
Profiles. Set 23 Toxicological Profiles
Toxicological profile
1.
2.
3.
4.
CAS No.
Acrylamide* ......................................................................................................................................
Carbon Monoxide* ...........................................................................................................................
1,3-Butadiene ..................................................................................................................................
Phosphate Ester Flame Retardants* ...............................................................................................
5. Vanadium .........................................................................................................................................
79–06–1
630–08–0
106–99–0
126–73–8, 126–71–6, 78–51–3, 115–86–6,
13674–84–5, 13674–87–8, 115–96–8
7440–62–2
* Denotes new profile.
The
Superfund Amendments and
Reauthorization Act of 1986 (SARA) (42
U.S.C. 9601 et seq.) amended the
Comprehensive Environmental
Response, Compensation, and Liability
Act of 1980 (CERCLA or Superfund) (42
U.S.C. 9601 et seq.) by establishing
certain requirements for ATSDR and the
U.S. Environmental Protection Agency
(EPA) with regard to hazardous
substances that are most commonly
found at facilities on the CERCLA
National Priorities List (NPL). Among
these statutory requirements is a
mandate for the Administrator of
ATSDR to prepare toxicological profiles
for each substance included on the
Priority List of Hazardous Substances
(https://www.atsdr.cdc.gov/cercla/
07list.html). This list names 275
hazardous substances that pose the most
significant potential threat to human
health as determined by ATSDR and
EPA. The availability of the revised list
of the 275 priority substances was
erowe on DSK5CLS3C1PROD with NOTICES
SUPPLEMENTARY INFORMATION:
VerDate Nov<24>2008
15:01 Jul 22, 2009
Jkt 217001
announced in the Federal Register on
March 6, 2008 (73 FR 12178). For prior
versions of the list of substances, see
Federal Register notices dated April 17,
1987 (52 FR 12866); October 20, 1988
(53 FR 41280); October 26, 1989 (54 FR
43619); October 17, 1990 (55 FR 42067);
October 17, 1991 (56 FR 52166); October
28, 1992 (57 FR 48801); February 28,
1994 (59 FR 9486); April 29, 1996 (61
FR 18744; November 17, 1997 (62 FR
61332); October 21, 1999 (64 FR 56792);
October 25, 2001 (66 FR 54014);
November 7, 2003 (68 FR 63098); and
December 7, 2005 (70 FR 70284).
The Set 23 Toxicological Profiles for
1,3-Butadiene and Vanadium are
updates of previously published profiles
for NPL priority substances. In addition,
to address emerging public health
concerns related to substances not
currently on the NPL, ATSDR is also
developing Set 23 Toxicological Profiles
for Carbon Monoxide, Acrylamide, and
Phosphate Ester Flame Retardants.
Carbon monoxide is a toxic gas
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Frm 00046
Fmt 4703
Sfmt 4703
produced from the incomplete
combustion of carbon-based fuels.
Because it is colorless and odorless,
toxicity can occur with no indication
that exposure is occurring. Thousands
of hospitalizations and hundreds of
deaths occur every year as a result of
inadvertent exposure to carbon
monoxide. Acrylamide is a known
animal carcinogen that is widely used in
industry to synthesize polyacrylamides.
Acrylamide also occurs naturally in a
few foods, is formed in many foods as
a byproduct of numerous cooking
processes, and has been detected
recently in human biomonitoring
studies. Phosphate ester flame
retardants comprise a large group of
structurally related chemicals with
increasing uses in clothing, fabrics,
furniture, and structural components.
However, there is an increasing body of
information regarding exposures, body
burdens, and toxicity related to this
group of chemicals.
E:\FR\FM\23JYN1.SGM
23JYN1
]]>Agencies
[Federal Register Volume 74, Number 140 (Thursday, July 23, 2009)]
[Notices]
[Pages 36492-36493]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-17529]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Agency for Toxic Substances and Disease Registry
[ATSDR-253]
Availability of Draft Toxicological Profile for Perfluoroalkyls
AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),
Department of Health and Human Services (HHS).
ACTION: Notice of availability.
-----------------------------------------------------------------------
SUMMARY: This notice announces the availability of the draft
toxicological profile for perfluoroalkyls, prepared by ATSDR, for
review and comment.
DATES: In order to be considered, comments on this draft toxicological
profile must be received on or before October 30, 2009. Comments
received after the public comment period will be considered at the
discretion of ATSDR on the basis of what is deemed to be in the best
interest of the general public.
ADDRESSES: Requests for a printed copy of the draft toxicological
profile should be sent to the attention of Ms. Olga Dawkins, Division
of Toxicology and Environmental Medicine, Agency for Toxic Substances
and Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta,
Georgia 30333. Electronic access to the document is also available at
the ATSDR Web site: https://www.atsdr.cdc.gov/toxpro2.html.
Requests for printed copies of the draft toxicological profile must
be in writing and must specifically identify the toxicological profile
that you wish to receive. ATSDR reserves the right to provide free of
charge only one copy of each profile requested. In case of extended
distribution delays, requestors will be notified.
Comments regarding the draft toxicological profile for
perfluoroalkyls should be sent to the attention of Ms. Nickolette
Roney, Division of Toxicology and Environmental Medicine, Agency for
Toxic Substances and Disease Registry, Mailstop F-62, 1600 Clifton
Road, NE., Atlanta, Georgia 30333. Electronic comments may be sent to
TPPublicComments@cdc.gov. All comments sent electronically should
contain the docket control number ATSDR-253 in the subject line.
Written comments and other data submitted in response to this
notice and the draft toxicological profile should bear the docket
control number ATSDR-253. Send one copy of all comments and three
copies of all supporting documents to Ms. Roney at the above address by
the end of the comment period. Because all public comments regarding
ATSDR toxicological profiles are available for public inspection, no
confidential information should be submitted in response to this
notice.
FOR FURTHER INFORMATION CONTACT: Ms. Olga Dawkins, Division of
Toxicology and Environmental Medicine, Agency for Toxic Substances and
Disease Registry, Mailstop F-62, 1600 Clifton Road, NE., Atlanta,
Georgia 30333; telephone number (800) 232-4636 or (770) 488-3315.
SUPPLEMENTARY INFORMATION: This draft toxicological profile for
perfluoroalkyls was prepared in accordance with guidelines developed by
the Agency for Toxic Substances and Disease Registry and the
Environmental Protection Agency (EPA) for the preparation of
toxicological profiles. The original guidelines were published in the
Federal Register on April 17, 1987. While perfluoroalkyls are not found
on the ATSDR Priority List of Hazardous Substances, ATSDR has
determined that a profile for these substances was necessary because
data indicate that some perfluoroalkyls are found in the blood of the
United States general population and in the environment. The agency
also determined that it was important to characterize the current
available information regarding the health effects from exposure to
perfluoroalkyls in order to support and inform public health responses
and activities by ATSDR and others. This profile will be revised and
republished as necessary.
Section 104(i)(3) of the Comprehensive Environmental Response,
Compensation, and Liability Act [42 U.S.C. 9604(i)(3)] outlines the
content of the toxicological profiles. Each profile includes an
examination, a summary, and an interpretation of available
toxicological information and epidemiologic evaluations. This
information and these data are to be used to identify the levels of
significant human exposure to a substance and the associated health
effects. The profiles must also include a determination of whether
adequate information on the health effects of each substance is
available or in the process of development. When adequate information
is not available, ATSDR, in cooperation with the National Toxicology
Program (NTP), will initiate a research program to determine these
health effects.
Although key studies for this substance were considered during the
profile development process, this Federal Register notice solicits any
additional studies, particularly unpublished data and ongoing studies,
which will be evaluated for possible addition to the profile now or in
the future.
[[Page 36493]]
The following draft toxicological profile will be made available to
the public on or about July 6, 2009.
------------------------------------------------------------------------
Document Toxicological profile CAS No.
------------------------------------------------------------------------
1............................... PERFLUOROALKYLS......... 000375-22-4
000335-67-1
001763-23-1
------------------------------------------------------------------------
All profiles issued as ``Draft for Public Comment'' represent
ATSDR's best efforts to provide important toxicological information on
priority substances. We are seeking public comments and additional
information that may be used to supplement this profile. ATSDR remains
committed to providing a public comment period for these documents as
the best means to serve public health and our clients.
Ken Rose,
Director, Office of Policy, Planning, and Evaluation, National Center
for Environmental Health/Agency for Toxic Substances and Disease
Registry.
[FR Doc. E9-17529 Filed 7-22-09; 8:45 am]
BILLING CODE 4163-70-P
