Human Studies Review Board; Notice of Public Meeting, 26861-26863 [E9-13061]
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Federal Register / Vol. 74, No. 106 / Thursday, June 4, 2009 / Notices
removal and treatment of sewage from
all vessels are reasonably available for
the Broad and Jackson Creeks, the
Fishing Bay and Porpoise Cove and
Moore Creek areas, in and around
Deltaville Virginia. The Commonwealth
of Virginia has demonstrated that there
is adequate and sufficient law
enforcement capability of these
regulations. The Commonwealth has
also submitted data to document that
local citizens, advocacy groups, and
marina personnel are concerned about
the adverse impacts from vessel sanitary
discharges into the Broad and Jackson
Creeks and Fishing Bay, and adjacent
areas. In response to public meetings in
May and June 2008, professional and
public comments were all supportive of
the decision to designate the affected
areas as a no discharge zone. There were
sufficient agency and environmental
groups’ comments to also support these
measures.
A final determination on this matter
will be made following the 30 day
period for public comment and may
result in a Virginia State prohibition of
any sewage discharges from vessels in
the Broad and Jackson Creeks and
Fishing Bay areas. Comments and views
regarding this application and EPA’s
tentative determination may be filed on
or before July 6, 2009. Comments or
requests for information or copies of the
application should be addressed to
Robert Runowski, EPA Region III, Office
of State and Watershed Partnerships,
1650 Arch Street, Philadelphia, PA
19103. E-mail: runowski.bob@epa.gov.
Telephone: (215) 814–5385. Fax: (215)
814–2301.
Dated: May 19, 2009.
William C. Early,
Acting Regional Administrator.
[FR Doc. E9–13059 Filed 6–3–09; 8:45 am]
BILLING CODE 6560–50–P
ENVIRONMENTAL PROTECTION
AGENCY
[EPA–HQ–ORD–2009–0183; FRL–8913–9]
Human Studies Review Board; Notice
of Public Meeting
AGENCY: Environmental Protection
Agency (EPA).
ACTION: Notice.
SUMMARY: The U.S. Environmental
Protection Agency’s (EPA or Agency)
Office of the Science Advisor (OSA)
announces a public meeting of the
Human Studies Review Board (HSRB) to
advise the Agency on EPA’s scientific
and ethical reviews of research with
human subjects.
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DATES: The public meeting will be held
from June 24, 2009 from approximately
9:30 a.m. to approximately 5:30 p.m.,
through June 25, 2009 from
approximately 8:30 a.m. to
approximately 4:30 p.m. Eastern Time.
Location: Holiday Inn National
Airport, 2605 Jefferson Davis Highway
(Crystal City), Arlington, VA 22202
(703–684–7200).
Meeting Access: Seating at the
meeting will be on a first-come basis. To
request accommodation of a disability
please contact the person listed under
FOR FURTHER INFORMATION CONTACT at
least 10 business days prior to the
meeting, to allow EPA as much time as
possible to process your request.
Procedures for Providing Public Input:
Interested members of the public may
submit relevant written or oral
comments for the HSRB to consider
during the advisory process. Additional
information concerning submission of
relevant written or oral comments is
provided in Unit I.D. of this notice.
FOR FURTHER INFORMATION CONTACT: Any
member of the public who wishes
further information should contact Jim
Downing, EPA, Office of the Science
Advisor, (8105R), Environmental
Protection Agency, 1200 Pennsylvania
Ave., NW., Washington, DC 20460;
telephone number: (202) 564–2468; fax:
(202) 564–2070; e-mail addresses:
downing.jim@epa.gov. General
information concerning the EPA HSRB
can be found on the EPA Web site at
https://www.epa.gov/osa/hsrb/.
ADDRESSES: Submit your written
comments, identified by Docket ID No.
EPA–HQ–ORD–2009–0183, by one of
the following methods:
Internet: https://www.regulations.gov:
Follow the on-line instructions for
submitting comments.
E-mail: ord.docket@epa.gov.
Mail: Environmental Protection
Agency, EPA Docket Center (EPA/DC),
ORD Docket, Mailcode: 28221T, 1200
Pennsylvania Ave., NW., Washington,
DC 20460.
Hand Delivery: The EPA/DC Public
Reading Room is located in the EPA
Headquarters Library, Room Number
3334 in the EPA West Building, located
at 1301 Constitution Ave., NW.,
Washington, DC. The hours of operation
are 8:30 a.m. to 4:30 p.m. Eastern Time,
Monday through Friday, excluding
Federal holidays. Please call (202) 566–
1744 or email the ORD Docket at
ord.docket@epa.gov for instructions.
Updates to Public Reading Room access
are available on the Web site (https://
www.epa.gov/epahome/dockets.htm).
Instructions: Direct your comments to
Docket ID No. EPA–HQ–ORD–2009–
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0183. EPA’s policy is that all comments
received will be included in the public
docket without change and may be
made available online at https://
www.regulations.gov, including any
personal information provided, unless
the comment includes information
claimed to be Confidential Business
Information (CBI) or other information
whose disclosure is restricted by statute.
Do not submit information that you
consider to be CBI or otherwise
protected through https://
www.regulations.gov or e-mail. The
https://www.regulations.gov website is
an ‘‘anonymous access’’ system, which
means EPA will not know your identity
or contact information unless you
provide it in the body of your comment.
If you send an e-mail comment directly
to EPA, without going through https://
www.regulations.gov, your e-mail
address will be automatically captured
and included as part of the comment
that is placed in the public docket and
made available on the Internet. If you
submit an electronic comment, EPA
recommends that you include your
name and other contact information in
the body of your comment and with any
disk or CD–ROM you submit. If EPA
cannot read your comment due to
technical difficulties and cannot contact
you for clarification, EPA may not be
able to consider your comment.
Electronic files should avoid the use of
special characters, any form of
encryption, and be free of any defects or
viruses.
SUPPLEMENTARY INFORMATION:
I. Public Meeting
A. Does This Action Apply to Me?
This action is directed to the public
in general. This action may, however, be
of interest to persons who conduct or
assess human studies, especially studies
on substances regulated by EPA or to
persons who are or may be required to
conduct testing of chemical substances
under the Federal Food, Drug, and
Cosmetic Act (FFDCA) or the Federal
Insecticide, Fungicide, and Rodenticide
Act (FIFRA). Since other entities may
also be interested, the Agency has not
attempted to describe all the specific
entities that may be affected by this
action. If you have any questions
regarding the applicability of this action
to a particular entity, consult the person
listed under FOR FURTHER INFORMATION
CONTACT.
B. How Can I Access Electronic Copies
of This Document and Other Related
Information?
In addition to using regulations.gov,
you may access this Federal Register
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Federal Register / Vol. 74, No. 106 / Thursday, June 4, 2009 / Notices
document electronically through the
EPA Internet under the ‘‘Federal
Register’’ listings at https://
www.epa.gov/fedrgstr/.
Docket: All documents in the docket
are listed in the https://
www.regulations.gov index. Although
listed in the index, some information is
not publicly available, e.g., CBI or other
information whose disclosure is
restricted by statute. Certain other
material, such as copyrighted material,
will be publicly available only in hard
copy. Publicly available docket
materials are available either
electronically in https://
www.regulations.gov or in hard copy at
the ORD Docket, EPA/DC, Public
Reading Room. The EPA/DC Public
Reading Room is located in the EPA
Headquarters Library, Room Number
3334 in the EPA West Building, located
at 1301 Constitution Ave., NW.,
Washington, DC. The hours of operation
are 8:30 a.m. to 4:30 p.m. EST, Monday
through Friday, excluding Federal
holidays. Please call (202) 566–1744 or
email the ORD Docket at
ord.docket@epa.gov for instructions.
Updates to Public Reading Room access
are available on the Web site (https://
www.epa.gov/epahome/dockets.htm).
EPA’s position paper(s), charge/
questions to the HSRB, and the meeting
agenda will be available by early June
2009. In addition, the Agency may
provide additional background
documents as the materials become
available. You may obtain electronic
copies of these documents, and certain
other related documents that might be
available electronically, from the
regulations.gov website and the EPA
HSRB website at https://www.epa.gov/
osa/hsrb/. For questions on document
availability or if you do not have access
to the Internet, consult the person listed
under FOR FURTHER INFORMATION.
C. What Should I Consider as I Prepare
My Comments for EPA?
You may find the following
suggestions helpful for preparing your
comments:
a. Explain your views as clearly as
possible.
b. Describe any assumptions that you
used.
c. Provide copies of any technical
information and/or data you used that
support your views.
d. Provide specific examples to
illustrate your concerns and suggest
alternatives.
e. To ensure proper receipt by EPA, be
sure to identify the docket ID number
assigned to this action in the subject
line on the first page of your response.
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You may also provide the name, date,
and Federal Register citation.
D. How May I Participate in This
Meeting?
You may participate in this meeting
by following the instructions in this
section. To ensure proper receipt by
EPA, it is imperative that you identify
docket ID number EPA–HQ–ORD–2009–
0183 in the subject line on the first page
of your request.
a. Oral comments. Requests to present
oral comments will be accepted up to
June 17, 2009. To the extent that time
permits, interested persons who have
not pre-registered may be permitted by
the Chair of the HSRB to present oral
comments at the meeting. Each
individual or group wishing to make
brief oral comments to the HSRB is
strongly advised to submit their request
(preferably via e-mail) to the person
listed under FOR FURTHER INFORMATION
CONTACT no later than noon, Eastern
time, June 17, 2009 in order to be
included on the meeting agenda and to
provide sufficient time for the HSRB
Chair and HSRB Designated Federal
Officer (DFO) to review the agenda to
provide an appropriate public comment
period. The request should identify the
name of the individual making the
presentation, the organization (if any)
the individual will represent, and any
requirements for audiovisual equipment
(e.g., overhead projector, LCD projector,
chalkboard). Oral comments before the
HSRB are limited to five minutes per
individual or organization. Please note
that this limit applies to the cumulative
time used by all individuals appearing
either as part of, or on behalf of an
organization. While it is our intent to
hear a full range of oral comments on
the science and ethics issues under
discussion, it is not our intent to permit
organizations to expand these time
limitations by having numerous
individuals sign up separately to speak
on their behalf. If additional time is
available, there may be flexibility in
time for public comments. Each speaker
should bring 25 copies of his or her
comments and presentation slides for
distribution to the HSRB at the meeting.
b. Written comments. Although you
may submit written comments at any
time, for the HSRB to have the best
opportunity to review and consider your
comments as it deliberates on its report,
you should submit your comments at
least five business days prior to the
beginning of the meeting. If you submit
comments after this date, those
comments will be provided to the Board
members, but you should recognize that
the Board members may not have
adequate time to consider those
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comments prior to making a decision.
Thus, if you plan to submit written
comments, the Agency strongly
encourages you to submit such
comments no later than noon, Eastern
Time, June 17, 2009. You should submit
your comments using the instructions in
Unit I.C. of this notice. In addition, the
Agency also requests that person(s)
submitting comments directly to the
docket also provide a copy of their
comments to the person listed under
FOR FURTHER INFORMATION CONTACT.
There is no limit on the length of
written comments for consideration by
the HSRB.
E. Background
A. Topics for Discussion
The HSRB is a Federal advisory
committee operating in accordance with
the Federal Advisory Committee Act
(FACA) 5 U.S.C. App. 2 section 9. The
HSRB provides advice, information, and
recommendations to EPA on issues
related to scientific and ethical aspects
of human subjects research. The major
objectives of the HSRB are to provide
advice and recommendations on: (1)
Research proposals and protocols; (2)
reports of completed research with
human subjects; and (3) how to
strengthen EPA’s programs for
protection of human subjects of
research. The HSRB reports to the EPA
Administrator through EPA’s Science
Advisor.
The June 24–25, 2009 meeting of the
Human Studies Review Board will
address scientific and ethical issues
surrounding:
• Four unpublished reports of
research completed before enactment of
the 2006 expanded EPA Regulation 40
CFR part 26 (Protection of Human
Subjects rule) on the organophosphate
pesticide chlorpyrifos:
a. A study by Coulston et al. (1972) of
the subacute oral toxicity of chlorpyrifos
to adult male prisoners.
b. A study by Nolan et al. (1982) of
the metabolism and excretion of
chlorpyrifos and cholinesterase activity
in adult males after a single oral or
dermal exposure.
c. A study by Honeycutt and DeGeare
(1993) monitoring the
Acetylcholinesterase activity and
urinary metabolites of chlorpyrifos in
agricultural workers who re-entered
chlorpyrifos-treated citrus groves.
d. A study by Kisicki et al. (1999) of
the acute oral toxicity of chlorpyrifos to
adult male and female volunteers.
• A proposal for new research to be
conducted by Carroll-Loye Biological
Research to evaluate the repellent
efficacy to biting flies in the field of two
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Federal Register / Vol. 74, No. 106 / Thursday, June 4, 2009 / Notices
registered products containing 20%
picaridin.
• The report of a completed
laboratory study conducted by ICR, Inc.,
to evaluate the repellent efficacy to
stable flies of two registered products
containing 20% picaridin.
• A new scenario design and
associated protocol for field studies at
five sites from the Agricultural Handlers
Exposure Task Force (AHETF),
describing proposed research to monitor
exposure of professional pesticide
handlers who mix and load pesticides
formulated as wettable powders in
water-soluble packaging.
In addition, the Board will be
reviewing its draft February 17, 2009
meeting report for subsequent Board
approval. Finally, the HSRB may also
discuss planning for future HSRB
meetings.
B. Meeting Minutes and Reports
Minutes of the meeting, summarizing
the matters discussed and
recommendations, if any, made by the
advisory committee regarding such
matters will be released within 90
calendar days of the meeting. Such
minutes will be available at https://
www.epa.gov/osa/hsrb/ and https://
www.regulations.gov. In addition,
information concerning a Board meeting
report, if applicable, can be found at
https://www.epa.gov/osa/hsrb/ or from
the person listed under FOR FURTHER
INFORMATION.
Dated: May 29, 2009.
Kevin Teichman,
EPA Acting Science Advisor.
[FR Doc. E9–13061 Filed 6–3–09; 8:45 am]
BILLING CODE 6560–50–P
ENVIRONMENTAL PROTECTION
AGENCY
[FRL–8913–4]
Proposed Settlement Agreement
AGENCY: Environmental Protection
Agency (EPA).
ACTION: Notice of proposed settlement
agreement; request for public comment.
SUMMARY: In accordance with section
113(g) of the Clean Air Act, as amended
(‘‘Act’’), 42 U.S.C. 7413(g), notice is
hereby given of a proposed settlement
agreement to address a lawsuit filed by
American Petroleum Institute (API) in
the United States Court of Appeals for
the District of Columbia Circuit:
American Petroleum Institute v. EPA,
No. 06–1321 (D.C. Cir.). API filed a
petition for review of an EPA rule
promulgating regulations requiring new
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source performance standards for new
stationary compression ignition internal
combustion engines. Under the terms of
the proposed settlement agreement, EPA
agrees to propose revisions to the new
source performance standards and to
issue guidance specifying particular
standards applicable under the
regulations.
DATES: Written comments on the
proposed settlement agreement must be
received by July 6, 2009.
ADDRESSES: Submit your comments,
identified by Docket ID number EPA–
HQ–OGC–2009–0354, Online at https://
www.regulations.gov (EPA’s preferred
method); by e-mail to
oei.docket@epa.gov; by mail to EPA
Docket Center, Environmental
Protection Agency, Mailcode: 2822T,
1200 Pennsylvania Ave., NW.,
Washington, DC 20460–0001; or by
hand delivery or courier to EPA Docket
Center, EPA West, Room 3334, 1301
Constitution Ave., NW., Washington,
DC, between 8:30 a.m. and 4:30 p.m.
Monday through Friday, excluding legal
holidays. Comments on a disk or CD–
ROM should be formatted in Word or
ASCII file, avoiding the use of special
characters and any form of encryption,
and may be mailed to the mailing
address above.
FOR FURTHER INFORMATION CONTACT:
Michael Horowitz, Air and Radiation
Law Office (2344A), Office of General
Counsel, U.S. Environmental Protection
Agency, 1200 Pennsylvania Ave., NW.,
Washington, DC 20460; telephone: (202)
564–5583; fax number (202) 564–5603;
e-mail address:
horowitz.michael@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Additional Information About the
Proposed Settlement Agreement
This proposed settlement agreement
would potentially resolve a petition for
judicial review filed by API for review
of a rule promulgating new source
performance standards for new
stationary compression ignition internal
combustion engines. Under the terms of
the proposed settlement agreement, EPA
agrees to propose, no later than one year
after execution of the settlement
agreement, revisions to the new source
performance standards. The proposed
revisions would allow owners and
operators more options in operating and
maintaining their engines, but would
require more testing for sources using
the additional options. The proposal
would also clarify certain provisions of
the existing regulations and make minor
modifications unrelated to the
stringency of the standards. After
considering any comment reviewed,
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26863
EPA agrees to sign a final rule within
one year of the publication of the
proposal. If the relevant provisions of
the final rule are in substantial
conformance with the revisions in the
draft agreement, then API agrees to the
dismissal of its petition for review.
Additionally, based on API concerns
that the regulations are not sufficiently
clear regarding the not-to-exceed
standards and multiples applicable to
engines subject to the regulations, EPA
agrees to issue guidance specifying the
not-to-exceed standards and multiples
applicable to such engines.
For a period of thirty (30) days
following the date of publication of this
notice, the Agency will accept written
comments relating to the proposed
settlement agreement from persons who
were not named as parties or
intervenors to the litigation in question.
EPA or the Department of Justice may
withdraw or withhold consent to the
proposed settlement agreement if the
comments disclose facts or
considerations that indicate that such
consent is inappropriate, improper,
inadequate, or inconsistent with the
requirements of the Act. Unless EPA or
the Department of Justice determines,
based on any comment submitted, that
consent to this settlement agreement
should be withdrawn, the terms of the
agreement will be affirmed.
II. Additional Information About
Commenting on the Proposed
Settlement Agreement
A. How Can I Get a Copy of the
Settlement Agreement?
The official public docket for this
action (identified by Docket ID No.
EPA–HQ–OGC–2009–0354) contains a
copy of the proposed settlement
agreement. The official public docket is
available for public viewing at the
Office of Environmental Information
(OEI) Docket in the EPA Docket Center,
EPA West, Room 3334, 1301
Constitution Ave., NW., Washington,
DC. The EPA Docket Center Public
Reading Room is open from 8:30 a.m. to
4:30 p.m., Monday through Friday,
excluding legal holidays. The telephone
number for the Public Reading Room is
(202) 566–1744, and the telephone
number for the OEI Docket is (202) 566–
1752.
An electronic version of the public
docket is available through https://
www.regulations.gov. You may use the
https://www.regulations.gov to submit or
view public comments, access the index
listing of the contents of the official
public docket, and to access those
documents in the public docket that are
available electronically. Once in the
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Agencies
[Federal Register Volume 74, Number 106 (Thursday, June 4, 2009)]
[Notices]
[Pages 26861-26863]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-13061]
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-ORD-2009-0183; FRL-8913-9]
Human Studies Review Board; Notice of Public Meeting
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The U.S. Environmental Protection Agency's (EPA or Agency)
Office of the Science Advisor (OSA) announces a public meeting of the
Human Studies Review Board (HSRB) to advise the Agency on EPA's
scientific and ethical reviews of research with human subjects.
DATES: The public meeting will be held from June 24, 2009 from
approximately 9:30 a.m. to approximately 5:30 p.m., through June 25,
2009 from approximately 8:30 a.m. to approximately 4:30 p.m. Eastern
Time.
Location: Holiday Inn National Airport, 2605 Jefferson Davis
Highway (Crystal City), Arlington, VA 22202 (703-684-7200).
Meeting Access: Seating at the meeting will be on a first-come
basis. To request accommodation of a disability please contact the
person listed under FOR FURTHER INFORMATION CONTACT at least 10
business days prior to the meeting, to allow EPA as much time as
possible to process your request.
Procedures for Providing Public Input: Interested members of the
public may submit relevant written or oral comments for the HSRB to
consider during the advisory process. Additional information concerning
submission of relevant written or oral comments is provided in Unit
I.D. of this notice.
FOR FURTHER INFORMATION CONTACT: Any member of the public who wishes
further information should contact Jim Downing, EPA, Office of the
Science Advisor, (8105R), Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington, DC 20460; telephone number: (202)
564-2468; fax: (202) 564-2070; e-mail addresses: downing.jim@epa.gov.
General information concerning the EPA HSRB can be found on the EPA Web
site at https://www.epa.gov/osa/hsrb/.
ADDRESSES: Submit your written comments, identified by Docket ID No.
EPA-HQ-ORD-2009-0183, by one of the following methods:
Internet: https://www.regulations.gov: Follow the on-line
instructions for submitting comments.
E-mail: ord.docket@epa.gov.
Mail: Environmental Protection Agency, EPA Docket Center (EPA/DC),
ORD Docket, Mailcode: 28221T, 1200 Pennsylvania Ave., NW., Washington,
DC 20460.
Hand Delivery: The EPA/DC Public Reading Room is located in the EPA
Headquarters Library, Room Number 3334 in the EPA West Building,
located at 1301 Constitution Ave., NW., Washington, DC. The hours of
operation are 8:30 a.m. to 4:30 p.m. Eastern Time, Monday through
Friday, excluding Federal holidays. Please call (202) 566-1744 or email
the ORD Docket at ord.docket@epa.gov for instructions. Updates to
Public Reading Room access are available on the Web site (https://www.epa.gov/epahome/dockets.htm).
Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2009-0183. EPA's policy is that all comments received will be included
in the public docket without change and may be made available online at
https://www.regulations.gov, including any personal information
provided, unless the comment includes information claimed to be
Confidential Business Information (CBI) or other information whose
disclosure is restricted by statute. Do not submit information that you
consider to be CBI or otherwise protected through https://www.regulations.gov or e-mail. The https://www.regulations.gov website
is an ``anonymous access'' system, which means EPA will not know your
identity or contact information unless you provide it in the body of
your comment. If you send an e-mail comment directly to EPA, without
going through https://www.regulations.gov, your e-mail address will be
automatically captured and included as part of the comment that is
placed in the public docket and made available on the Internet. If you
submit an electronic comment, EPA recommends that you include your name
and other contact information in the body of your comment and with any
disk or CD-ROM you submit. If EPA cannot read your comment due to
technical difficulties and cannot contact you for clarification, EPA
may not be able to consider your comment. Electronic files should avoid
the use of special characters, any form of encryption, and be free of
any defects or viruses.
SUPPLEMENTARY INFORMATION:
I. Public Meeting
A. Does This Action Apply to Me?
This action is directed to the public in general. This action may,
however, be of interest to persons who conduct or assess human studies,
especially studies on substances regulated by EPA or to persons who are
or may be required to conduct testing of chemical substances under the
Federal Food, Drug, and Cosmetic Act (FFDCA) or the Federal
Insecticide, Fungicide, and Rodenticide Act (FIFRA). Since other
entities may also be interested, the Agency has not attempted to
describe all the specific entities that may be affected by this action.
If you have any questions regarding the applicability of this action to
a particular entity, consult the person listed under FOR FURTHER
INFORMATION CONTACT.
B. How Can I Access Electronic Copies of This Document and Other
Related Information?
In addition to using regulations.gov, you may access this Federal
Register
[[Page 26862]]
document electronically through the EPA Internet under the ``Federal
Register'' listings at https://www.epa.gov/fedrgstr/.
Docket: All documents in the docket are listed in the https://www.regulations.gov index. Although listed in the index, some
information is not publicly available, e.g., CBI or other information
whose disclosure is restricted by statute. Certain other material, such
as copyrighted material, will be publicly available only in hard copy.
Publicly available docket materials are available either electronically
in https://www.regulations.gov or in hard copy at the ORD Docket, EPA/
DC, Public Reading Room. The EPA/DC Public Reading Room is located in
the EPA Headquarters Library, Room Number 3334 in the EPA West
Building, located at 1301 Constitution Ave., NW., Washington, DC. The
hours of operation are 8:30 a.m. to 4:30 p.m. EST, Monday through
Friday, excluding Federal holidays. Please call (202) 566-1744 or email
the ORD Docket at ord.docket@epa.gov for instructions. Updates to
Public Reading Room access are available on the Web site (https://www.epa.gov/epahome/dockets.htm).
EPA's position paper(s), charge/questions to the HSRB, and the
meeting agenda will be available by early June 2009. In addition, the
Agency may provide additional background documents as the materials
become available. You may obtain electronic copies of these documents,
and certain other related documents that might be available
electronically, from the regulations.gov website and the EPA HSRB
website at https://www.epa.gov/osa/hsrb/. For questions on document
availability or if you do not have access to the Internet, consult the
person listed under FOR FURTHER INFORMATION.
C. What Should I Consider as I Prepare My Comments for EPA?
You may find the following suggestions helpful for preparing your
comments:
a. Explain your views as clearly as possible.
b. Describe any assumptions that you used.
c. Provide copies of any technical information and/or data you used
that support your views.
d. Provide specific examples to illustrate your concerns and
suggest alternatives.
e. To ensure proper receipt by EPA, be sure to identify the docket
ID number assigned to this action in the subject line on the first page
of your response. You may also provide the name, date, and Federal
Register citation.
D. How May I Participate in This Meeting?
You may participate in this meeting by following the instructions
in this section. To ensure proper receipt by EPA, it is imperative that
you identify docket ID number EPA-HQ-ORD-2009-0183 in the subject line
on the first page of your request.
a. Oral comments. Requests to present oral comments will be
accepted up to June 17, 2009. To the extent that time permits,
interested persons who have not pre-registered may be permitted by the
Chair of the HSRB to present oral comments at the meeting. Each
individual or group wishing to make brief oral comments to the HSRB is
strongly advised to submit their request (preferably via e-mail) to the
person listed under FOR FURTHER INFORMATION CONTACT no later than noon,
Eastern time, June 17, 2009 in order to be included on the meeting
agenda and to provide sufficient time for the HSRB Chair and HSRB
Designated Federal Officer (DFO) to review the agenda to provide an
appropriate public comment period. The request should identify the name
of the individual making the presentation, the organization (if any)
the individual will represent, and any requirements for audiovisual
equipment (e.g., overhead projector, LCD projector, chalkboard). Oral
comments before the HSRB are limited to five minutes per individual or
organization. Please note that this limit applies to the cumulative
time used by all individuals appearing either as part of, or on behalf
of an organization. While it is our intent to hear a full range of oral
comments on the science and ethics issues under discussion, it is not
our intent to permit organizations to expand these time limitations by
having numerous individuals sign up separately to speak on their
behalf. If additional time is available, there may be flexibility in
time for public comments. Each speaker should bring 25 copies of his or
her comments and presentation slides for distribution to the HSRB at
the meeting.
b. Written comments. Although you may submit written comments at
any time, for the HSRB to have the best opportunity to review and
consider your comments as it deliberates on its report, you should
submit your comments at least five business days prior to the beginning
of the meeting. If you submit comments after this date, those comments
will be provided to the Board members, but you should recognize that
the Board members may not have adequate time to consider those comments
prior to making a decision. Thus, if you plan to submit written
comments, the Agency strongly encourages you to submit such comments no
later than noon, Eastern Time, June 17, 2009. You should submit your
comments using the instructions in Unit I.C. of this notice. In
addition, the Agency also requests that person(s) submitting comments
directly to the docket also provide a copy of their comments to the
person listed under FOR FURTHER INFORMATION CONTACT. There is no limit
on the length of written comments for consideration by the HSRB.
E. Background
A. Topics for Discussion
The HSRB is a Federal advisory committee operating in accordance
with the Federal Advisory Committee Act (FACA) 5 U.S.C. App. 2 section
9. The HSRB provides advice, information, and recommendations to EPA on
issues related to scientific and ethical aspects of human subjects
research. The major objectives of the HSRB are to provide advice and
recommendations on: (1) Research proposals and protocols; (2) reports
of completed research with human subjects; and (3) how to strengthen
EPA's programs for protection of human subjects of research. The HSRB
reports to the EPA Administrator through EPA's Science Advisor.
The June 24-25, 2009 meeting of the Human Studies Review Board will
address scientific and ethical issues surrounding:
Four unpublished reports of research completed before
enactment of the 2006 expanded EPA Regulation 40 CFR part 26
(Protection of Human Subjects rule) on the organophosphate pesticide
chlorpyrifos:
a. A study by Coulston et al. (1972) of the subacute oral toxicity
of chlorpyrifos to adult male prisoners.
b. A study by Nolan et al. (1982) of the metabolism and excretion
of chlorpyrifos and cholinesterase activity in adult males after a
single oral or dermal exposure.
c. A study by Honeycutt and DeGeare (1993) monitoring the
Acetylcholinesterase activity and urinary metabolites of chlorpyrifos
in agricultural workers who re-entered chlorpyrifos-treated citrus
groves.
d. A study by Kisicki et al. (1999) of the acute oral toxicity of
chlorpyrifos to adult male and female volunteers.
A proposal for new research to be conducted by Carroll-
Loye Biological Research to evaluate the repellent efficacy to biting
flies in the field of two
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registered products containing 20% picaridin.
The report of a completed laboratory study conducted by
ICR, Inc., to evaluate the repellent efficacy to stable flies of two
registered products containing 20% picaridin.
A new scenario design and associated protocol for field
studies at five sites from the Agricultural Handlers Exposure Task
Force (AHETF), describing proposed research to monitor exposure of
professional pesticide handlers who mix and load pesticides formulated
as wettable powders in water-soluble packaging.
In addition, the Board will be reviewing its draft February 17,
2009 meeting report for subsequent Board approval. Finally, the HSRB
may also discuss planning for future HSRB meetings.
B. Meeting Minutes and Reports
Minutes of the meeting, summarizing the matters discussed and
recommendations, if any, made by the advisory committee regarding such
matters will be released within 90 calendar days of the meeting. Such
minutes will be available at https://www.epa.gov/osa/hsrb/ and https://www.regulations.gov. In addition, information concerning a Board
meeting report, if applicable, can be found at https://www.epa.gov/osa/hsrb/ or from the person listed under FOR FURTHER INFORMATION.
Dated: May 29, 2009.
Kevin Teichman,
EPA Acting Science Advisor.
[FR Doc. E9-13061 Filed 6-3-09; 8:45 am]
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