National Institute on Deafness and Other Communication Disorders; Notice of Closed Meeting, 4755-4756 [E9-1665]

Download as PDF Federal Register / Vol. 74, No. 16 / Tuesday, January 27, 2009 / Notices Bethesda, MD 20892, 301–594–4859, horsforj@mail.nih.gov. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel, Review K23s, R03, F32. Date: March 4, 2009. Time: 2 p.m. to 3 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892. (Telephone Conference Call) Contact Person: Mary Kelly, Scientific Review Officer, Scientific Review Branch, National Inst of Dental & Craniofacial Research, NIH, 6701 Democracy Blvd., Room 672, MSC 4878, Bethesda, MD 20892–4878, 301–594–4809, mary_kelly@nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.121, Oral Diseases and Disorders Research, National Institutes of Health, HHS) Dated: January 16, 2009. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. E9–1661 Filed 1–26–09; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Mental Health; Notice of Closed Meeting mstockstill on PROD1PC66 with NOTICES6 Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of a meeting of the Board of Scientific Counselors, National Institute of Mental Health. The meeting will be closed to the public as indicated below in accordance with the provisions set forth in section 552b(c)(6), Title 5 U.S.C., as amended for the review, discussion, and evaluation of individual intramural programs and projects conducted by the National Institute of Mental Health, including consideration of personnel qualifications and performance, and the competence of individual investigators, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Board of Scientific Counselors, National Institute of Mental Health. Date: February 9–11, 2009. Time: February 9, 2009, 7 p.m. to 10 p.m. Agenda: To review and evaluate personal qualifications and performance, and competence of individual investigators. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Time: February 10, 2009, 8:30 a.m. to 11:40 a.m. Agenda: To review and evaluate the Intramural Laboratories with site visits of the VerDate Nov<24>2008 17:20 Jan 26, 2009 Jkt 217001 Section on Fundamental Neuroscience, Unit on Behavioral Genetics, Laboratory of Molecular Pathophysiology, and the Section on Molecular Neuroscience. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852. Time: February 10, 2009, 11:40 a.m. to 4 p.m. Agenda: To review and evaluate personal qualifications and performance, and competence of individual investigators. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852. Time: February 10, 2009, 7 p.m. to 10 p.m. Agenda: To review and evaluate personal qualifications and performance, and competence of individual investigators. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Time: February 11, 2009, 8:30 a.m. to 11:50 a.m. Agenda: To review and evaluate the Intramural Laboratories with site visits of the Genes, Cognition and Psychosis Program, the Section on Clinical Studies, and the Section on Neuropathology. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Time: February 11, 2009, 11:50 a.m. to 12:10 p.m. Agenda: To review and evaluate personal qualifications and performance, and competence of individual investigators. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Time: February 11, 2009, 11:50 a.m. to 12:50 p.m. Agenda: To review and evaluate site visits with Training Fellows and Staff Scientists. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Time: February 11, 2009, 12:50 p.m. to 4 p.m. Agenda: To review and evaluate personal qualifications and performance, and competence of individual investigators. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Contact Person: Dawn M. Johnson, PhD, Executive Secretary, Division of Intramural Research Programs, National Institute of Mental Health, 10 Center Drive, Building 10, Room 4N222, Bethesda, MD 20892, 301–402– 5234, dawnjohnson@mail.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.242, Mental Health Research Grants; 93.281, Scientist Development Award, Scientist Development Award for Clinicians, and Research Scientist Award; 93.282, Mental Health National Research Service Awards for Research Training, National Institutes of Health, HHS) Dated: January 16, 2009. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. E9–1663 Filed 1–26–09; 8:45 am] BILLING CODE 4140–01–P PO 00000 Frm 00025 Fmt 4703 Sfmt 4703 4755 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Neurological Sciences Training Initial Review Group; NST–1 Subcommittee. Date: January 26–27, 2009. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate grant applications. Place: Renaissance Mayflower Hotel, 1127 Connecticut Avenue, NW., Washington, DC 20036. Contact Person: Raul A. Saavedra, PhD, Scientific Review Officer, Scientific Review Branch, Division of Extramural Research, NINDS/NIH/DHHS, NSC; 6001 Executive Blvd., Ste. 3208, Bethesda, MD 20892–9529, 301–496–9223, saavedrr@ninds.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.853, Clinical Research Related to Neurological Disorders; 93.854, Biological Basis Research in the Neurosciences, National Institutes of Health, HHS) Dated: January 16, 2009. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. E9–1664 Filed 1–26–09; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Deafness and Other Communication Disorders; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as E:\FR\FM\27JAN1.SGM 27JAN1 4756 Federal Register / Vol. 74, No. 16 / Tuesday, January 27, 2009 / Notices amended (5 U.S.C. Appendix 2), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Communication Disorders Review Committee. Date: February 11–13, 2009. Time: February 11, 2009, 8 p.m. to 10 p.m. Agenda: To review and evaluate grant applications. Place: Baltimore Marriott Waterfront, 700 Aliceanna Street, Baltimore, MD 21202. Time: February 12, 2009, 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Baltimore Marriott Waterfront, 700 Aliceanna Street, Baltimore, MD 21202. Time: February 13, 2009, 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Baltimore Marriott Waterfront, 700 Aliceanna Street, Baltimore, MD 21202. Contact Person: Shiguang Yang, DVM, PhD, Scientific Review Officer, Scientific Review Branch, Division of Extramural Activities, NIDCD, NIH, 6120 Executive Blvd., Suite 400C, Bethesda, MD 20892, 301– 435–1425, yangshi@nidcd.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.173, Biological Research Related to Deafness and Communicative Disorders, National Institutes of Health, HHS) Dated: January 16, 2009. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. E9–1665 Filed 1–26–09; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES DATES: Only written comments and/or application for a license, which are received by the NIH Office of Technology Transfer on or before March 30, 2009 will be considered. National Institutes of Health mstockstill on PROD1PC66 with NOTICES6 Prospective Grant of Exclusive License: Multi-Domain Amphipathic Helical Peptides for the Treatment of Cardiovascular Diseases SUMMARY: This is notice, in accordance with 35 U.S.C. 209(c)(1) and 37 CFR 404.7(a)(1)(i), that the National Institutes of Health (NIH), Department of Health and Human Services (HHS), is 17:20 Jan 26, 2009 Jkt 217001 Requests for a copy of the patent applications, inquiries, comments and other materials relating to the contemplated license should be directed to: Fatima Sayyid, M.H.P.M., Senior Licensing and Patenting Manager, Office of Technology Transfer, National Institutes of Health, 6011 Executive Boulevard, Suite 325, Rockville, MD 20852–3804; Telephone: (301) 435–4521; Facsimile: (301) 402– ADDRESSES: AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION: Notice. VerDate Nov<24>2008 contemplating the grant of an exclusive license worldwide to practice the invention embodied in: United States Provisional Patent Application No. 60/ 619,392, filed October 15, 2004, entitled ‘‘Multi-Domain Amphipathic Helical Peptides and Methods of Their Use’’ (HHS Ref. No. E–114–2004/0–US–01), United States Patent Application Serial No. 11/577,259, filed April 13, 2007, entitled ‘‘Multi-Domain Amphipathic Helical Peptides and Methods of Their Use’’ (HHS Ref. No. E–114–2004/0–US– 07); Australian Patent Application Serial No. 2005295640, filed October 14, 2005, entitled ‘‘Multi-Domain Amphipathic Helical Peptides and Methods of Their Use’’ (HHS Ref. No. E– 114–2004/0–AU–03); Canadian Patent Application Serial No. 2584048, filed October 14, 2005, entitled ‘‘MultiDomain Amphipathic Helical Peptides and Methods of Their Use’’ (HHS Ref. No. E–114–2004/0–CA–04); European Patent Application Serial No. 05815961.7, filed October 14, 2005, entitled ‘‘Multi-Domain Amphipathic Helical Peptides and Methods of Their Use’’ (HHS Ref. No. E–114–2004/0–EP– 05); Japanese Patent Application Serial No. 2007–536912, filed October 14, 2005, entitled ‘‘Multi-Domain Amphipathic Helical Peptides and Methods of Their Use’’ (HHS Ref. No. E– 114–2004/0–JP–06) to KineMed, Inc., having a place of business in the State of California. The field of use may be limited to FDA or foreign regulatory body approved 5a peptide therapeutic for the prevention and treatment of cardiovascular diseases. The United States of America is the assignee of the patent rights in this invention. The territory may be worldwide. This announcement is the second notice to grant an exclusive license to this technology and supersedes any previous announcements including the Notice published in the Federal Register on Wednesday, May 11, 2005 (70 FR 24832). PO 00000 Frm 00026 Fmt 4703 Sfmt 4703 0220; e-mail: Fatima.Sayyid@nih.hhs.gov. Clearance of excess cholesterol from cells by high density lipoproteins (HDL) is facilitated by the interaction of HDL apolipoprotein with cell surface binding sites or receptors such as ABCA1. ABCA1 is a member of the ATP binding cassette transporter family and is expressed by many cell types. Mutations in the ABCA1 transporter lead to diseases characterized by the accumulation of excess cellular cholesterol, low levels of HDL and an increased risk for cardiovascular disease. Research has demonstrated an inverse correlation between the occurrence of atherosclerotic events and levels of HDL and its most abundant protein constituent, apolipoprotein A–1 (apoA–1). ApoA–1 has been shown to promote lipid efflux from ABCA1 transfected cells. However, the nature of the interaction between apoA–1 and ABCA1 is not fully understood. Several other exchangeable type apolipoproteins have been shown to efflux lipid from ABCA1 transfected cells. Although the exchangeable type apolipoproteins do not share a similar primary amino acid sequence, they all contain amphipathic helices, a structural motif known to facilitate the interaction of proteins with lipids. Recently, it has been shown in both animal models and humans that intravenous administration of apoA–1 can reduce the size of atherosclerotic plaques. It has also been observed that synthetic peptide mimics of apoA–1 can promote efflux of excess cholesterol from cells. Therefore, synthetic mimics of apoA–1 can potentially also be used as therapeutic compounds in the prevention and treatment of atherosclerosis. Currently, there are a wide variety of treatments for dyslipidemia, which include, but are not limited to, pharmacologic regimens (mostly statins), partial ileal bypass surgery, portacaval shunt, liver transplantation, and removal of atherogenic lipoproteins by one of several apheresis procedures. The subject technology is related to peptides and peptide analogs with multiple amphipathic alpha-helical domains that promote lipid efflux from cells and it relates to methods for identifying non-cytotoxic peptides that promote lipid efflux from cells that are useful in the treatment and prevention of dyslipidemic and vascular disorders. Dyslipidemic and vascular disorders amenable to treatment with the isolated multi-domain peptides include, but are not limited to, hyperlipidemia, hyperlipoproteinemia, SUPPLEMENTARY INFORMATION: E:\FR\FM\27JAN1.SGM 27JAN1

Agencies

[Federal Register Volume 74, Number 16 (Tuesday, January 27, 2009)]
[Notices]
[Pages 4755-4756]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-1665]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Institute on Deafness and Other Communication Disorders; 
Notice of Closed Meeting

    Pursuant to section 10(d) of the Federal Advisory Committee Act, as

[[Page 4756]]

amended (5 U.S.C. Appendix 2), notice is hereby given of the following 
meeting.
    The meeting will be closed to the public in accordance with the 
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 
U.S.C., as amended. The grant applications and the discussions could 
disclose confidential trade secrets or commercial property such as 
patentable material, and personal information concerning individuals 
associated with the grant applications, the disclosure of which would 
constitute a clearly unwarranted invasion of personal privacy.

    Name of Committee: Communication Disorders Review Committee.
    Date: February 11-13, 2009.
    Time: February 11, 2009, 8 p.m. to 10 p.m.
    Agenda: To review and evaluate grant applications.
    Place: Baltimore Marriott Waterfront, 700 Aliceanna Street, 
Baltimore, MD 21202.
    Time: February 12, 2009, 8 a.m. to 5 p.m.
    Agenda: To review and evaluate grant applications.
    Place: Baltimore Marriott Waterfront, 700 Aliceanna Street, 
Baltimore, MD 21202.
    Time: February 13, 2009, 8 a.m. to 5 p.m.
    Agenda: To review and evaluate grant applications.
    Place: Baltimore Marriott Waterfront, 700 Aliceanna Street, 
Baltimore, MD 21202.
    Contact Person: Shiguang Yang, DVM, PhD, Scientific Review 
Officer, Scientific Review Branch, Division of Extramural 
Activities, NIDCD, NIH, 6120 Executive Blvd., Suite 400C, Bethesda, 
MD 20892, 301-435-1425, yangshi@nidcd.nih.gov.

(Catalogue of Federal Domestic Assistance Program Nos. 93.173, 
Biological Research Related to Deafness and Communicative Disorders, 
National Institutes of Health, HHS)

    Dated: January 16, 2009.
Jennifer Spaeth,
Director, Office of Federal Advisory Committee Policy.
 [FR Doc. E9-1665 Filed 1-26-09; 8:45 am]
BILLING CODE 4140-01-P
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