Draft Toxicological Review of Tetrachloroethylene (Perchloroethylene): In Support of Summary Information on the Integrated Risk Information System (IRIS), 36321-36322 [E8-14521]

Download as PDF Federal Register / Vol. 73, No. 124 / Thursday, June 26, 2008 / Notices may be viewed and downloaded from the following SAB Web site at https:// yosemite.epa.gov/sab/sabproduct.nsf/ WebSABSO/Form3110-48/$File/ epaform3110-48.pdf. The approved policy under which the EPA SAB Office selects subcommittees and review panels is described on the ‘‘Overview of the Panel Formation Process’’ page on the SAB Web site at https://yosemite.epa.gov/sab/ sabproduct.nsf/WebSABSO/ OverviewPanelForm?OpenDocument. Dated: June 19, 2008. Anthony F. Maciorowski, Deputy Director, EPA Science Advisory Board Staff Office. [FR Doc. E8–14511 Filed 6–25–08; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY [FRL–8685–6; Docket ID No. EPA–HQ–ORD– 2008–0461] Draft Toxicological Review of Tetrachloroethylene (Perchloroethylene): In Support of Summary Information on the Integrated Risk Information System (IRIS) Environmental Protection Agency (EPA). ACTION: Notice of Public Comment Period. rfrederick on PROD1PC67 with NOTICES AGENCY: SUMMARY: EPA is announcing a 90-day public comment period for the draft document entitled, ‘‘Toxicological Review of Tetrachloroethylene (Perchloroethylene): In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ (EPA/ 635/R–08/011A). The document was prepared by the National Center for Environmental Assessment (NCEA) within EPA’s Office of Research and Development. The draft tetrachloroethylene health assessment addresses both potential cancer and non-cancer human health effects that may result from chronic exposure to tetrachloroethylene. Tetrachloroethylene, commonly referred to as ‘‘perc’’, is a solvent widely used in the dry cleaning of clothes and as a metal degreaser. EPA intends to consider comments and recommendations from the public and the expert panel meeting, which will be announced at a later date, when EPA finalizes the draft document. The public comment period will provide opportunities for all interested parties to comment on the document. EPA intends to forward public comments, submitted VerDate Aug<31>2005 15:05 Jun 25, 2008 Jkt 214001 in accordance with this notice, to the external peer-review panel prior to the peer review meeting for their consideration. EPA is releasing this draft document solely for the purpose of predissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. EPA will consider any public comments submitted in accordance with this notice when revising the document. The draft document is available via the Internet on NCEA’s homepage under the Recent Additions and the Data and Publications menus at https:// www.epa.gov/ncea. DATES: The 90-day public comment period begins June 26, 2008, and ends September 24, 2008. Technical comments should be in writing and must be received by EPA by September 24, 2008. EPA intends to submit comments from the public received by this date for consideration by the external peer review panel. The draft tetrachloroethylene assessment will be independently peer reviewed by an expert panel convened by The National Academies’ Board on Environmental Studies and Toxicology (BEST). Information on the first meeting of the BEST tetrachloroethylene panel, expected to be held in late fall 2008, will be posted on The National Academies’ Web site at https:// www8.nationalacademies.org/cp/ projectview.aspx?key=48697. Note that due to the need to provide the public comments to the peer review panel one month prior to their first meeting, an extension of the public comment beyond the 90 days provided will not be possible. EPA has lengthened the comment period for tetrachloroethylene beyond the usual 60 days allotted for IRIS assessments because of the expected high interest in this draft assessment. ADDRESSES: The draft ‘‘Toxicological Review of Tetrachloroethylene (Perchloroethylene): In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ is available primarily via the Internet on NCEA’s home page under the Recent Additions and the Data and Publications menus at https://www.epa.gov/ncea. A limited number of paper copies are available by contacting the Information Management Team, NCEA; telephone: 703–347–8561; facsimile: 703–347– 8691. If you are requesting a paper copy, please provide your name, your mailing PO 00000 Frm 00027 Fmt 4703 Sfmt 4703 36321 address, and the document title, ‘‘Toxicological Review of Tetrachloroethylene (Perchloroethylene): In Support of Summary Information on the Integrated Risk Information System (IRIS).’’ Comments may be submitted electronically via https:// www.regulations.gov, by mail, by facsimile, or by hand delivery/courier. Please follow the detailed instructions provided in the SUPPLEMENTARY INFORMATION section of this notice. FOR FURTHER INFORMATION CONTACT: For information on the public comment period, contact the Office of Environmental Information Docket; telephone: 202–566–1752; facsimile: 202–566–1753; or e-mail: ORD.Docket@epa.gov. For technical information on the draft assessment, contact the Information Management Team by (phone: 703–347– 8561; fax: 703–347–8691; or e-mail: nceadc.comment@epa.gov). SUPPLEMENTARY INFORMATION: I. Summary Information About the Integrated Risk Information System (IRIS) IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at https://www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 540 chemical substances that may be used to support the first two steps (hazard identification and doseresponse evaluation) of the risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic non-cancer health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with exposure information, government and private entities use IRIS to help characterize the public health risks of chemical substances and thereby support risk management decisions designed to protect public health. II. How to Submit Technical Comments to the Docket at https:// www.regulations.gov Submit your comments, identified by Docket ID No. EPA–HQ–ORD 2008– 0461, by one of the following methods: • https://www.regulations.gov: Follow the on-line instructions for submitting comments. • E-mail: ORD.Docket@epa.gov. E:\FR\FM\26JNN1.SGM 26JNN1 rfrederick on PROD1PC67 with NOTICES 36322 Federal Register / Vol. 73, No. 124 / Thursday, June 26, 2008 / Notices • Fax: 202–566–1753. • Mail: Office of Environmental Information (OEI) Docket (Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202–566–1752. • Hand Delivery: The OEI Docket is located in the EPA Headquarters Docket Center, Room 3334 EPA West Building, 1301 Constitution Ave., NW., Washington, DC. The EPA Docket Center Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is 202–566–1744. Such deliveries are only accepted during the docket’s normal hours of operation, and special arrangements should be made for deliveries of boxed information. If you provide comments by mail or hand delivery, please submit three copies of the comments. For attachments, provide an index, number pages consecutively with the comments, and submit an unbound original and three copies. Instructions: Direct your comments to Docket ID No. EPA–HQ–ORD–2008– 0461. Please ensure that your comments are submitted within the specified comment period. Comments received after the closing date will be marked ‘‘late,’’ and may only be considered if time permits. It is EPA’s policy to include all comments it receives in the public docket without change and to make the comments available online at https://www.regulations.gov, including any personal information provided, unless a comment includes information claimed to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through https:// www.regulations.gov or e-mail. The https://www.regulations.gov Web site is an ‘‘anonymous access’’ system, which means EPA will not know your identity or contact information unless you provide it in the body of your comment. If you send an e-mail comment directly to EPA without going through https:// www.regulations.gov, your e-mail address will be automatically captured and included as part of the comment that is placed in the public docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CD-ROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact VerDate Aug<31>2005 15:05 Jun 25, 2008 Jkt 214001 you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form of encryption, and be free of any defects or viruses. For additional information about EPA’s public docket visit the EPA Docket Center homepage at www.epa.gov/epahome/dockets.htm. Docket: Documents in the docket are listed in the https://www.regulations.gov index. Although listed in the index, some information is not publicly available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other materials, such as copyrighted material, are publicly available only in hard copy. Publicly available docket materials are available either electronically in https:// www.regulations.gov or in hard copy at the OEI Docket in the EPA Headquarters Docket Center. Dated: June 20, 2008. Rebecca Clark, Acting Director, National Center for Environmental Assessment. [FR Doc. E8–14521 Filed 6–25–08; 8:45 am] FEDERAL COMMUNICATIONS COMMISSION Notice of Public Information Collection(s) Being Submitted for Review to the Office of Management and Budget, Comments Requested June 20, 2008. SUMMARY: As part of its continuing effort to reduce paperwork burden and as required by the Paperwork Reduction Act (PRA) of 1995 (44 U.S.C. 3501– 3520), the Federal Communications Commission invites the general public and other Federal agencies to comment on the following information collection(s). Comments are requested concerning: (a) Whether the proposed collection of information is necessary for the proper performance of the functions of the Commission, including whether the information shall have practical utility; (b) the accuracy of the Commission’s burden estimate; (c) ways to enhance the quality, utility, and clarity of the information collected; and (d) ways to minimize the burden of the collection of information on the respondents, including the use of automated collection techniques or other forms of information technology. An agency may not conduct or sponsor a collection of information unless it displays a currently valid OMB control number. No person shall be subject to any penalty for failing to comply with Frm 00028 Fmt 4703 For additional information contact Leslie F. Smith via e-mail at PRA@fcc.gov or at (202) 418–0217. To view or obtain a copy of an information collection request (ICR) submitted to OMB: (1) Go to this OMB/GSA Web page: https:// www.reginfo.gov/public/do/PRAMain, (2) look for the section of the Web page called ‘‘Currently Under Review,’’ (3) click on the downward-pointing arrow in the ‘‘Select Agency’’ box below the ‘‘Currently Under Review’’ heading, (4) select ‘‘Federal Communications Commission’’ from the list of agencies presented in the ‘‘Select Agency’’ box, (5) click the ‘‘Submit’’ button to the right of the ‘‘Select Agency’’ box, and (6) when the list of FCC ICRs currently under review appears, look for the OMB control number of the ICR you want to view (or its title if there is no OMB control number) and then click on the ICR Reference Number. A copy of the FCC submission to OMB will be displayed. FOR FURTHER INFORMATION CONTACT: BILLING CODE 6560–50–P PO 00000 a collection of information subject to the Paperwork Reduction Act that does not display a valid OMB control number. DATES: Written PRA comments should be submitted on or before July 28, 2008. If you anticipate that you will be submitting PRA comments, but find it difficult to do so within the period of time allowed by this notice, you should advise the FCC contact listed below as soon as possible. ADDRESSES: Submit your comments to Nicholas A. Fraser, Office of Management and Budget (e-mail address: nfraser@omb.eop.gov), and to the Federal Communications Commission’s PRA mailbox (e-mail address: PRA@fcc.gov). Include in the emails the OMB control number of the collection as shown in the SUPPLEMENTARY INFORMATION section below or, if there is no OMB control number, the Title as shown in the SUPPLEMENTARY INFORMATION section. If you are unable to submit your comments by e-mail contact the person listed below to make alternate arrangements. Sfmt 4703 SUPPLEMENTARY INFORMATION: OMB Control Number: 3060–0819. Title: Sections 54.400–54.417, Lifeline Assistance (Lifeline) Connection Assistance (Link-Up) Reporting Worksheet and Instructions, FCC Form 497. Form Number(s): FCC Form 497. Type of Review: Revision of a currently approved collection. Respondents: Individuals or households; and business or other forprofit. E:\FR\FM\26JNN1.SGM 26JNN1

Agencies

[Federal Register Volume 73, Number 124 (Thursday, June 26, 2008)]
[Notices]
[Pages 36321-36322]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E8-14521]


-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

[FRL-8685-6; Docket ID No. EPA-HQ-ORD-2008-0461]


Draft Toxicological Review of Tetrachloroethylene 
(Perchloroethylene): In Support of Summary Information on the 
Integrated Risk Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of Public Comment Period.

-----------------------------------------------------------------------

SUMMARY: EPA is announcing a 90-day public comment period for the draft 
document entitled, ``Toxicological Review of Tetrachloroethylene 
(Perchloroethylene): In Support of Summary Information on the 
Integrated Risk Information System (IRIS)'' (EPA/635/R-08/011A). The 
document was prepared by the National Center for Environmental 
Assessment (NCEA) within EPA's Office of Research and Development. The 
draft tetrachloroethylene health assessment addresses both potential 
cancer and non-cancer human health effects that may result from chronic 
exposure to tetrachloroethylene. Tetrachloroethylene, commonly referred 
to as ``perc'', is a solvent widely used in the dry cleaning of clothes 
and as a metal degreaser.
    EPA intends to consider comments and recommendations from the 
public and the expert panel meeting, which will be announced at a later 
date, when EPA finalizes the draft document. The public comment period 
will provide opportunities for all interested parties to comment on the 
document. EPA intends to forward public comments, submitted in 
accordance with this notice, to the external peer-review panel prior to 
the peer review meeting for their consideration.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination. EPA will consider any public comments 
submitted in accordance with this notice when revising the document.
    The draft document is available via the Internet on NCEA's homepage 
under the Recent Additions and the Data and Publications menus at 
https://www.epa.gov/ncea.

DATES: The 90-day public comment period begins June 26, 2008, and ends 
September 24, 2008. Technical comments should be in writing and must be 
received by EPA by September 24, 2008. EPA intends to submit comments 
from the public received by this date for consideration by the external 
peer review panel.
    The draft tetrachloroethylene assessment will be independently peer 
reviewed by an expert panel convened by The National Academies' Board 
on Environmental Studies and Toxicology (BEST). Information on the 
first meeting of the BEST tetrachloroethylene panel, expected to be 
held in late fall 2008, will be posted on The National Academies' Web 
site at https://www8.nationalacademies.org/cp/
projectview.aspx?key=48697. Note that due to the need to provide the 
public comments to the peer review panel one month prior to their first 
meeting, an extension of the public comment beyond the 90 days provided 
will not be possible. EPA has lengthened the comment period for 
tetrachloroethylene beyond the usual 60 days allotted for IRIS 
assessments because of the expected high interest in this draft 
assessment.

ADDRESSES: The draft ``Toxicological Review of Tetrachloroethylene 
(Perchloroethylene): In Support of Summary Information on the 
Integrated Risk Information System (IRIS)'' is available primarily via 
the Internet on NCEA's home page under the Recent Additions and the 
Data and Publications menus at https://www.epa.gov/ncea. A limited 
number of paper copies are available by contacting the Information 
Management Team, NCEA; telephone: 703-347-8561; facsimile: 703-347-
8691. If you are requesting a paper copy, please provide your name, 
your mailing address, and the document title, ``Toxicological Review of 
Tetrachloroethylene (Perchloroethylene): In Support of Summary 
Information on the Integrated Risk Information System (IRIS).''
    Comments may be submitted electronically via https://
www.regulations.gov, by mail, by facsimile, or by hand delivery/
courier. Please follow the detailed instructions provided in the 
SUPPLEMENTARY INFORMATION section of this notice.

FOR FURTHER INFORMATION CONTACT: For information on the public comment 
period, contact the Office of Environmental Information Docket; 
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail: 
ORD.Docket@epa.gov.
    For technical information on the draft assessment, contact the 
Information Management Team by (phone: 703-347-8561; fax: 703-347-8691; 
or e-mail: nceadc.comment@epa.gov).

SUPPLEMENTARY INFORMATION:

I. Summary Information About the Integrated Risk Information System 
(IRIS)

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at https://www.epa.gov/iris) contains 
qualitative and quantitative health effects information for more than 
540 chemical substances that may be used to support the first two steps 
(hazard identification and dose-response evaluation) of the risk 
assessment process. When supported by available data, the database 
provides oral reference doses (RfDs) and inhalation reference 
concentrations (RfCs) for chronic non-cancer health effects, and oral 
slope factors and inhalation unit risks for carcinogenic effects. 
Combined with exposure information, government and private entities use 
IRIS to help characterize the public health risks of chemical 
substances and thereby support risk management decisions designed to 
protect public health.

II. How to Submit Technical Comments to the Docket at https://
www.regulations.gov

    Submit your comments, identified by Docket ID No. EPA-HQ-ORD 2008-
0461, by one of the following methods:
     https://www.regulations.gov: Follow the on-line 
instructions for submitting comments.
     E-mail: ORD.Docket@epa.gov.

[[Page 36322]]

     Fax: 202-566-1753.
     Mail: Office of Environmental Information (OEI) Docket 
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
     Hand Delivery: The OEI Docket is located in the EPA 
Headquarters Docket Center, Room 3334 EPA West Building, 1301 
Constitution Ave., NW., Washington, DC. The EPA Docket Center Public 
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the Public 
Reading Room is 202-566-1744. Such deliveries are only accepted during 
the docket's normal hours of operation, and special arrangements should 
be made for deliveries of boxed information.
    If you provide comments by mail or hand delivery, please submit 
three copies of the comments. For attachments, provide an index, number 
pages consecutively with the comments, and submit an unbound original 
and three copies.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2008-0461. Please ensure that your comments are submitted within the 
specified comment period. Comments received after the closing date will 
be marked ``late,'' and may only be considered if time permits. It is 
EPA's policy to include all comments it receives in the public docket 
without change and to make the comments available online at https://
www.regulations.gov, including any personal information provided, 
unless a comment includes information claimed to be Confidential 
Business Information (CBI) or other information whose disclosure is 
restricted by statute. Do not submit information that you consider to 
be CBI or otherwise protected through https://www.regulations.gov or e-
mail. The https://www.regulations.gov Web site is an ``anonymous 
access'' system, which means EPA will not know your identity or contact 
information unless you provide it in the body of your comment. If you 
send an e-mail comment directly to EPA without going through https://
www.regulations.gov, your e-mail address will be automatically captured 
and included as part of the comment that is placed in the public docket 
and made available on the Internet. If you submit an electronic 
comment, EPA recommends that you include your name and other contact 
information in the body of your comment and with any disk or CD-ROM you 
submit. If EPA cannot read your comment due to technical difficulties 
and cannot contact you for clarification, EPA may not be able to 
consider your comment. Electronic files should avoid the use of special 
characters, any form of encryption, and be free of any defects or 
viruses. For additional information about EPA's public docket visit the 
EPA Docket Center homepage at www.epa.gov/epahome/dockets.htm.
    Docket: Documents in the docket are listed in the https://
www.regulations.gov index. Although listed in the index, some 
information is not publicly available, e.g., CBI or other information 
whose disclosure is restricted by statute. Certain other materials, 
such as copyrighted material, are publicly available only in hard copy. 
Publicly available docket materials are available either electronically 
in https://www.regulations.gov or in hard copy at the OEI Docket in the 
EPA Headquarters Docket Center.

    Dated: June 20, 2008.
Rebecca Clark,
Acting Director, National Center for Environmental Assessment.
 [FR Doc. E8-14521 Filed 6-25-08; 8:45 am]
BILLING CODE 6560-50-P