Notice of Availability for the Framework for Application of the Toxicity Equivalence Methodology for Polychlorinated Dioxins, Furans, and Biphenyls in Ecological Risk Assessment, 34015 [E8-13484]
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phone/voice mail at: (202) 564–9945;
via fax at: (202) 565–2911; or via e-mail
at: susanke.greg@epa.gov.
SUPPLEMENTARY INFORMATION:
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The meeting is open to the public.
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receiving a draft BOSC agenda or
making a presentation at the meeting
may contact Greg Susanke, the
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draft subcommittee report which
includes overall comments and
recommendations to ORD’s National
Homeland Security Research Program,
and responses to subcommittee charge
questions.
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information on access or services for
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VerDate Aug<31>2005
17:04 Jun 13, 2008
Jkt 214001
contact Greg Susanke, preferably at least
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Dated: June 9, 2008.
Mary Ellen Radzikowski,
Acting Office Director, Office of Science
Policy.
[FR Doc. E8–13483 Filed 6–13–08; 8:45 am]
BILLING CODE 6560–50–P
ENVIRONMENTAL PROTECTION
AGENCY
[EPA–HQ–ORD–2003–0002; FRL–8579–7]
Notice of Availability for the
Framework for Application of the
Toxicity Equivalence Methodology for
Polychlorinated Dioxins, Furans, and
Biphenyls in Ecological Risk
Assessment
Environmental Protection
Agency (EPA).
ACTION: Notice of document availability.
AGENCY:
SUMMARY: The U.S. Environmental
Protection Agency (EPA) is announcing
the availability of the final ‘‘Framework
for Application of the Toxicity
Equivalence Methodology for
Polychlorinated Dioxins, Furans, and
Biphenyls in Ecological Risk
Assessment’’ (EPA/100/R–08/004). The
purpose of the Framework is to assist
EPA scientists in using the toxicity
equivalence methodology to assess
ecological risks from mixtures of dioxinlike chemicals, i.e., polychlorinated
dibenzo-p-dioxins (PCDDs),
dibenzofurans (PCDFs), and biphenyls
(PCBs), as well as to inform EPA
decision makers, other agencies, and the
public about this methodology. This
framework provides an introduction to
the toxicity equivalence methodology,
offers considerations for how and when
to apply the methodology, and presents
practical examples of its use. The
Framework thus serves to enhance the
application of the best available science.
This document is not intended to serve
as guidance on how to conduct a
comprehensive risk assessment for
dioxin-like chemicals or to act as a
regulation or binding policy. EPA’s Risk
Assessment Forum oversaw the
development of this document,
incorporating input obtained from an
expert workshop, scientists throughout
the Agency, stakeholders, and a peer
review by twelve experts from a range
of scientific disciplines.
ADDRESSES: The final document is
available electronically through the EPA
Office of the Science Advisor’s Web site
at: https://www.epa.gov/osa/raf/
PO 00000
Frm 00045
Fmt 4703
Sfmt 4703
34015
tefframework/. A limited number of
paper copies will be available from
EPA’s National Service Center for
Environmental Publications (NSCEP),
P.O. Box 42419, Cincinnati, OH 45242;
telephone 1–800–490–9198 or 513–489–
8190; facsimile 301–604–3408; e-mail
NSCEP@bps-lmit.com. Please provide
your name and mailing addresses and
the title and EPA number (as given
above) of the requested publication.
FOR FURTHER INFORMATION CONTACT:
Seema Schappelle, Risk Assessment
Forum, Mail Code 8105R,
Environmental Protection Agency, 1200
Pennsylvania Avenue, NW.,Washington,
DC 20460; telephone number: (202)
564–3372; fax number: (202) 564–2070,
E-mail: schappelle.seema@epa.gov.
SUPPLEMENTARY INFORMATION: For more
than a decade, EPA and other
organizations have estimated the
combined risks that mixtures of PCDDs,
PCDFs, and PCBs pose to human health
using the toxicity equivalence
methodology. As both data and
experience with the methodology have
accumulated, experts have come to the
consensus that the toxicity equivalence
methodology can strengthen
assessments of ecological risks as well.
In 1998, EPA and DOI sponsored a
workshop that recommended the
development of further guidance on
application of the toxicity equivalence
methodology in ecological risk
assessment. This framework has been
developed in direct response to that
workshop recommendation. EPA
consulted with other federal agencies at
key points during the document’s
development. In July 2003, EPA
released a draft Framework for a 60-day
public comment period. An external
peer review was conducted in 2004 by
twelve experts from a range of scientific
disciplines.
Dated: May 15, 2008.
George M. Gray,
EPA Science Advisor.
[FR Doc. E8–13484 Filed 6–13–08; 8:45 am]
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[Federal Register Volume 73, Number 116 (Monday, June 16, 2008)]
[Notices]
[Page 34015]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E8-13484]
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-ORD-2003-0002; FRL-8579-7]
Notice of Availability for the Framework for Application of the
Toxicity Equivalence Methodology for Polychlorinated Dioxins, Furans,
and Biphenyls in Ecological Risk Assessment
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of document availability.
-----------------------------------------------------------------------
SUMMARY: The U.S. Environmental Protection Agency (EPA) is announcing
the availability of the final ``Framework for Application of the
Toxicity Equivalence Methodology for Polychlorinated Dioxins, Furans,
and Biphenyls in Ecological Risk Assessment'' (EPA/100/R-08/004). The
purpose of the Framework is to assist EPA scientists in using the
toxicity equivalence methodology to assess ecological risks from
mixtures of dioxin-like chemicals, i.e., polychlorinated dibenzo-p-
dioxins (PCDDs), dibenzofurans (PCDFs), and biphenyls (PCBs), as well
as to inform EPA decision makers, other agencies, and the public about
this methodology. This framework provides an introduction to the
toxicity equivalence methodology, offers considerations for how and
when to apply the methodology, and presents practical examples of its
use. The Framework thus serves to enhance the application of the best
available science. This document is not intended to serve as guidance
on how to conduct a comprehensive risk assessment for dioxin-like
chemicals or to act as a regulation or binding policy. EPA's Risk
Assessment Forum oversaw the development of this document,
incorporating input obtained from an expert workshop, scientists
throughout the Agency, stakeholders, and a peer review by twelve
experts from a range of scientific disciplines.
ADDRESSES: The final document is available electronically through the
EPA Office of the Science Advisor's Web site at: https://www.epa.gov/
osa/raf/tefframework/. A limited number of paper copies will be
available from EPA's National Service Center for Environmental
Publications (NSCEP), P.O. Box 42419, Cincinnati, OH 45242; telephone
1-800-490-9198 or 513-489-8190; facsimile 301-604-3408; e-mail
NSCEP@bps-lmit.com. Please provide your name and mailing addresses and
the title and EPA number (as given above) of the requested publication.
FOR FURTHER INFORMATION CONTACT: Seema Schappelle, Risk Assessment
Forum, Mail Code 8105R, Environmental Protection Agency, 1200
Pennsylvania Avenue, NW.,Washington, DC 20460; telephone number: (202)
564-3372; fax number: (202) 564-2070, E-mail: schappelle.seema@epa.gov.
SUPPLEMENTARY INFORMATION: For more than a decade, EPA and other
organizations have estimated the combined risks that mixtures of PCDDs,
PCDFs, and PCBs pose to human health using the toxicity equivalence
methodology. As both data and experience with the methodology have
accumulated, experts have come to the consensus that the toxicity
equivalence methodology can strengthen assessments of ecological risks
as well. In 1998, EPA and DOI sponsored a workshop that recommended the
development of further guidance on application of the toxicity
equivalence methodology in ecological risk assessment. This framework
has been developed in direct response to that workshop recommendation.
EPA consulted with other federal agencies at key points during the
document's development. In July 2003, EPA released a draft Framework
for a 60-day public comment period. An external peer review was
conducted in 2004 by twelve experts from a range of scientific
disciplines.
Dated: May 15, 2008.
George M. Gray,
EPA Science Advisor.
[FR Doc. E8-13484 Filed 6-13-08; 8:45 am]
BILLING CODE 6560-50-P