Notice of Meeting; Chairpersons, Boards of Scientific Counselors for Institutes/Centers at the NIH, 30409 [E8-11715]

Download as PDF Federal Register / Vol. 73, No. 102 / Tuesday, May 27, 2008 / Notices pwalker on PROD1PC71 with NOTICES This application claims use of suppressive oligonucleotides to suppress lung inflammation. More specifically, the application claims use of suppressive oligonucleotides for the treatment, prevention, or inhibition of pneumonia, ARDS, and chronic bronchitis. Applications: Vaccine adjuvants, production of vaccines, immunotherapeutics. Development Status: Preclinical studies have been performed; oligonucleotides have been synthesized. Inventors: Dennis Klinman (FDA/ CBER; NCI) and Hiroshi Yamada (CBER/ FDA). Patent Status: U.S. Provisional Application No. 60/417,263 filed 08 Oct 2002 (HHS Reference Number E–183– 2002/0–US–01); U.S. Patent Application No. 10/682,130 filed 07 Oct 2003 (HHS Reference Number E–183–2002/0–US– 02). Licensing Status: Available for exclusive or nonexclusive licensing. Licensing Contact: Peter A. Soukas, J.D.; 301–435–4646; soukasp@mail.nih.gov. Collaborative Research Opportunity: The National Cancer Institute, Laboratory of Experimental Immunology, Immune Modulation Group, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact John D. Hewes, Ph.D. at 301– 435–3121 or hewesj@mail.nih.gov for more information. Method of Treating and Preventing Infections in Immunocompromised Subjects With Immunostimulatory CpG Oligonucleotides Description of Technology: Primary disorders of the immune system can be divided into four categories, (1) disorders of the humoral immunity, (2) disorders of cellular immunity, (3) disorders of phagocytes, and (4) disorders of complement. In addition, there are many causes of secondary immunodeficiency such as treatment with immunosuppressive or chemotherapeutic agents, protein-losing enteropathy, and infection with a human immunodeficiency virus (HIV). Generally, immunocompromised patients are unable to mount an immune response to a vaccine or an infection in the same manner as nonimmunocompromised individuals. Opportunistic infections to which individuals infected with HIV are susceptible include bacterial infections such as salmonellosis, syphilis and neurosyphilis, tuberculosis (TB), a VerDate Aug<31>2005 17:22 May 23, 2008 Jkt 214001 typical mycobacterial infection, and bacillary angiomatosis (cat scratch disease), fungal infections such as aspergillosis, candidiasis (thrush, yeast infection), coccidioidomycosis, cryptococcal meningitis, and histoplasmosis, protozoal infections such as cryptosporidiosis, isosporiasis, microsporidiosis, Pneumocystis Carinii pneumonia (PCP), and toxoplasmosis, viral infections such as Cytomegalovirus (CMV), hepatitis, herpes simplex (HSV, genital herpes), herpes zoster (HZV, shingles), human papilloma virus (HPV, genital warts, cervical cancer), Molluscum Contagiosum, oral hairy leukoplakia (OHL), and progressive multifocal leukoencephalopathy (PML), and neoplasms such as Kaposi’s sarcoma, systemic non-Hodgkin’s lymphoma (NHL), and primary CNS lymphoma, among others. These opportunistic infections remain principally responsible for the morbidity and mortality associated with HIV disease. This application claims use of immunostimulatory D-type CpG oligonucleotides for the treatment of immunocompromised individuals. More specifically, the application claims use of immunostimulatory D-type CpG oligonucleotides for the treatment of individuals infected with HIV. Application: Vaccine adjuvants, production of vaccines, immunotherapeutics. Development Status: Preclinical studies have been performed; oligonucleotides have been synthesized. Inventors: Dennis Klinman (FDA/ CBER; NCI) and Daniela Verthelyi (FDA/CBER). Patent Status: U.S. Provisional Application No. 60/411,944 filed 18 Sep 2002 (HHS Reference No. E–153–2002/ 0–US–01); U.S. Patent Application No. 10/666,022 filed 17 Sep 2003 (HHS Reference No. E–153–2002/0–US–03). Licensing Status: Available for exclusive or nonexclusive licensing. Licensing Contact: Peter A. Soukas, J.D.; 301–435–4646; soukasp@mail.nih.gov. Collaborative Research Opportunity: The National Cancer Institute, Laboratory of Experimental Immunology, Immune Modulation Group, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact John D. Hewes, PhD at 301–435– 3121 or hewesj@mail.nih.gov for more information. PO 00000 Frm 00035 Fmt 4703 Sfmt 4703 30409 Dated: May 15, 2008. Steven M. Ferguson, Director, Division of Technology Development and Transfer, Office of Technology Transfer, National Institutes of Health. [FR Doc. E8–11698 Filed 5–23–08; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Notice of Meeting; Chairpersons, Boards of Scientific Counselors for Institutes/Centers at the NIH Notice is hereby given of a meeting scheduled by the Deputy Director for Intramural Research at the National Institutes of Health (NIH) with the Chairpersons of the Boards of Scientific Counselors. The Boards of Scientific Counselors are advisory groups to the Scientific Directors of the Intramural Research Programs at the NIH. This meeting will take place on June 30, 2008, from 10 a.m. to 3 p.m., at the NIH, 1 Center Drive, Bethesda, MD, Building 1, Wilson Hall. The meeting will include a discussion of policies and procedures that apply to the regular review of NIH intramural scientists and their work, with special emphasis on clinical research. The meeting will be open to the public, with attendance limited to space available. Individuals who plan to attend and need special assistance, such as sign language interpretation or other reasonable accommodations, should contact Ms. Colleen Crone at the Office of Intramural Research, NIH, Building 1, Room 160, Telephone (301) 496–1921 or FAX (301) 402–4273 in advance of the meeting. Dated: April 30, 2008. Raynard S. Kington, Deputy Director, NIH. [FR Doc. E8–11715 Filed 5–23–08; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Mental Health; Notice of Meeting Notice is hereby given of a meeting of the Services Subcommittee of the Interagency Autism Coordinating Committee (IACC). The purpose of the Services Subcommittee is to review the current state of services and supports for individuals with Autism Spectrum E:\FR\FM\27MYN1.SGM 27MYN1

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[Federal Register Volume 73, Number 102 (Tuesday, May 27, 2008)]
[Notices]
[Page 30409]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E8-11715]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Notice of Meeting; Chairpersons, Boards of Scientific Counselors 
for Institutes/Centers at the NIH

    Notice is hereby given of a meeting scheduled by the Deputy 
Director for Intramural Research at the National Institutes of Health 
(NIH) with the Chairpersons of the Boards of Scientific Counselors. The 
Boards of Scientific Counselors are advisory groups to the Scientific 
Directors of the Intramural Research Programs at the NIH. This meeting 
will take place on June 30, 2008, from 10 a.m. to 3 p.m., at the NIH, 1 
Center Drive, Bethesda, MD, Building 1, Wilson Hall. The meeting will 
include a discussion of policies and procedures that apply to the 
regular review of NIH intramural scientists and their work, with 
special emphasis on clinical research.
    The meeting will be open to the public, with attendance limited to 
space available. Individuals who plan to attend and need special 
assistance, such as sign language interpretation or other reasonable 
accommodations, should contact Ms. Colleen Crone at the Office of 
Intramural Research, NIH, Building 1, Room 160, Telephone (301) 496-
1921 or FAX (301) 402-4273 in advance of the meeting.

    Dated: April 30, 2008.
Raynard S. Kington,
Deputy Director, NIH.
[FR Doc. E8-11715 Filed 5-23-08; 8:45 am]
BILLING CODE 4140-01-P