Draft Toxicological Review of 2-Hexanone: In Support of the Summary Information in the Integrated Risk Information System (IRIS), 21941-21942 [E8-8797]

Download as PDF Federal Register / Vol. 73, No. 79 / Wednesday, April 23, 2008 / Notices 21941 II. 16 NOTICES OF COMMENCEMENT FROM: 3/1/08 TO 3/21/08—Continued Case No. Commencement Notice End Date Received Date P–07–0311 P–07–0557 P–07–0588 P–07–0673 P–07–0686 P–07–0697 03/13/08 03/13/08 03/03/08 03/17/08 03/11/08 03/12/08 02/26/08 02/28/08 02/25/08 03/07/08 02/29/08 03/04/08 P–07–0700 P–08–0061 P–08–0074 P–08–0078 P–91–0862 03/03/08 03/04/08 03/10/08 03/17/08 03/13/08 02/18/08 02/19/08 02/16/08 03/10/08 10/15/91 List of Subjects Environmental protection, Chemicals, Premanufacturer notices. Dated: April 16, 2008. Todd S. Holderman, Acting Director, Information Management Division, Office of Pollution Prevention and Toxics. [FR Doc. E8–8796 Filed 4–22–08; 8:45 am] BILLING CODE 6560–50–S ENVIRONMENTAL PROTECTION AGENCY [FRL–8556–5; Docket ID No. EPA–HQ–ORD– 2008–0048] Draft Toxicological Review of 2Hexanone: In Support of the Summary Information in the Integrated Risk Information System (IRIS) Environmental Protection Agency (EPA). ACTION: Notice. mstockstill on PROD1PC66 with NOTICES AGENCY: SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for external scientific peer review, will convene an independent panel of experts and organize and conduct an external peer-review meeting to review the external review draft document titled, ‘‘Toxicological Review of 2Hexanone: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ (NCEA-S– 2764). EPA previously announced the 60-day public comment period (ending April 28, 2008) for the draft document in the Federal Register on March 4, 2008 (73 FR 11408). EPA will consider public comments and recommendations from the expert panel meeting as EPA finalizes the draft document. The public comment period and the external peer-review meeting are separate processes that provide opportunities for all interested parties to comment on the document. EPA intends VerDate Aug<31>2005 16:58 Apr 22, 2008 Jkt 214001 Chemical (G) Polyester acrylate (G) Urethane acrylate (G) Alkyl nitrile (S) 2(3H)-furanone,5-(6-heptenyl)dihydro(G) Polyetheramine (G) Alkanedioc acid, polymer with isocyanate, alkyl diols, and substituted alkenoate, alkylamine-blocked, compounds with substituted alkanol (G) Polyester resin (G) Alcohol, reaction products with alkylene oxide, alkenyl glycidyl ether sulfate (G) Aliphatic polyisocyanate, C16-alcohol and polyalkylene glycol-blocked (G) Plant oil (G) Capped polyurea to forward public comments submitted in accordance with Federal Register (73 FR 11408) to Versar, Inc., for consideration by the external peerreview panel prior to the meeting. EPA is releasing this draft document solely for the purpose of predissemination peer review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. Versar, Inc., invites the public to register to attend this meeting as observers. In addition, Versar, Inc., invites the public to give brief oral comments at the meeting regarding the draft document under review. The draft document and EPA’s peer-review charge are available via the Internet on the National Center for Environmental Assessment’s (NCEA) home page under the Recent Additions and the Data and Publications menus at https:// www.epa.gov/ncea. When finalizing the draft document, EPA intends to consider Versar’s report of the comments and recommendations from the external peer-review meeting and any public comments that EPA receives in accordance with 73 FR 11408, March 4, 2008. Public comments that were submitted during the 60-day public comment period ending April 28, 2008 may be observed at https:// www.regulations.gov under Docket ID No. EPA–HQ–ORD–2008–0048. DATES: The peer-review panel meeting will begin on May 22, 2008, at 9 a.m. and end at 5 p.m. Register by May 16, 2008, if you wish to provide brief oral comments at the meeting. ADDRESSES: The peer-review meeting will be held at the Courtyard by Marriott Crystal City, 2899 Jefferson Davis Highway, Arlington, VA 22202. Versar, Inc., is organizing, convening, and conducting the peer-review meeting. To PO 00000 Frm 00042 Fmt 4703 Sfmt 4703 attend the meeting, register by May 16, 2008, via the Internet at https:// epa.versar.com/2hexanone/. The draft ‘‘Toxicological Review of 2Hexanone: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ is available via the Internet on the National Center for Environmental Assessment’s (NCEA) home page under the Recent Additions and the Data and Publications menus at https://www.epa.gov/ncea. A limited number of paper copies are available from the Information Management Staff, NCEA; telephone: 703–347–8561; facsimile: 703–347–8691. If you are requesting a paper copy, please provide your name, mailing address, and the document title. Copies are not available from Versar, Inc. FOR FURTHER INFORMATION CONTACT: For information on the peer review meeting, contact Stephanie Sarraino, Versar, Inc.; telephone: 703–750–3000 ext. 316; email: ssarraino@versar.com. If you have questions about the document, contact Amanda S. Persad, IRIS Staff, National Center for Environmental Assessment (B–243–01), U.S. EPA, Research Triangle Park, NC, 27711; telephone: 919–541–9781; facsimile: 919–541–1818; e-mail: persad.amanda@epa.gov. SUPPLEMENTARY INFORMATION: I. Summary of Information About the Integrated Risk Information System (IRIS) IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at https://www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 500 chemical substances that may be used to support the first two steps (hazard identification and dose- E:\FR\FM\23APN1.SGM 23APN1 21942 Federal Register / Vol. 73, No. 79 / Wednesday, April 23, 2008 / Notices response evaluation) of a risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with specific exposure information, government and private entities can use IRIS data to help characterize public health risks of chemical substances in a site-specific situation and thereby support risk management decisions designed to protect public health. II. Meeting Information Members of the public may attend the meeting as observers, and there will be a limited time for oral comments from the public. Please let Versar, Inc. know if you wish to make comments during the meeting by registering on the Web site at https://epa.versar.com/ 2hexanone/ and indicating your intent to make oral comments. Space is limited, and reservations will be accepted on a first-come, first-served basis. Dated: April 15, 2008. Peter W. Preuss, Director, National Center for Environmental Assessment. [FR Doc. E8–8797 Filed 4–22–08; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY [EPA–HQ–OPP–2008–0303; FRL–8361–2] Fenamiphos; Notice of Receipt of Request to Voluntarily Cancel Certain Pesticide Registrations Environmental Protection Agency (EPA). ACTION: Notice. mstockstill on PROD1PC66 with NOTICES AGENCY: SUMMARY: In accordance with section 6(f)(1) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, EPA is issuing a notice of receipt of a request by a registrant to voluntarily cancel its registrations for all products containing the pesticide fenamiphos. This notice announces receipt by EPA of a request from the registrant Bayer CropScience to cancel the remaining fenamiphos product registrations. The request would terminate the last fenamiphos products registered for use in the United States. The last remaining fenamiphos products registered under FIFRA Section 3 were cancelled on May 31, 2007 as stipulated in a Federal Register notice issued on December 10, 2003 VerDate Aug<31>2005 16:58 Apr 22, 2008 Jkt 214001 (FRL–7332–5). However, several FIFRA 24(c) Special Local Needs registrations (for nematode and banana root borer control) have not gone through the voluntary cancellation process. Bayer CropScience, the registrant for all of the active FIFRA 24(c) product registrations, has requested cancellation of all fenamiphos Special Local Needs registrations associated with the previously cancelled Section 3 fenamiphos products. EPA intends to grant this request at the close of the comment period for this announcement unless the Agency receives substantive comments within the comment period that would merit its further review of the request, or unless the registrant withdraws their request within this period. Upon acceptance of this request, any sale, distribution, or use of products listed in this notice will be permitted only if such sale, distribution, or use is consistent with the terms as described in the final order. DATES: Comments must be received on or May 23, 2008. ADDRESSES: Submit your comments and your withdrawal request, identified by docket identification (ID) number EPA– HQ–OPP–2008–0303, by one of the following methods: • Federal eRulemaking Portal: https:// www.regulations.gov. Follow the on-line instructions for submitting comments. • Mail: Office of Pesticide Programs (OPP) Regulatory Public Docket (7502P), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460–0001. • Delivery: OPP Regulatory Public Docket (7502P), Environmental Protection Agency, Rm. S–4400, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. Deliveries are only accepted during the Docket’s normal hours of operation (8:30 a.m. to 4 p.m., Monday through Friday, excluding legal holidays). Special arrangements should be made for deliveries of boxed information. The Docket Facility telephone number is (703) 305–5805. Instructions: Direct your comments to docket ID number EPA–HQ–OPP–2008– 0303. EPA’s policy is that all comments received will be included in the docket without change and may be made available on-line at https:// www.regulations.gov, including any personal information provided, unless the comment includes information claimed to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through regulations.gov or e- PO 00000 Frm 00043 Fmt 4703 Sfmt 4703 mail. The regulations.gov website is an ‘‘anonymous access’’ system, which means EPA will not know your identity or contact information unless you provide it in the body of your comment. If you send an e-mail comment directly to EPA without going through regulations.gov, your e-mail address will be automatically captured and included as part of the comment that is placed in the docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CD-ROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form of encryption, and be free of any defects or viruses. Docket: All documents in the docket are listed in the docket index available in regulations.gov. To access the electronic docket, go to https:// www.regulations.gov, select ‘‘Advanced Search,’’ then ‘‘Docket Search.’’ Insert the docket ID number where indicated and select the ‘‘Submit’’ button. Follow the instructions on the regulations.gov website to view the docket index or access available documents. Although listed in the index, some information is not publicly available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other material, such as copyrighted material, is not placed on the Internet and will be publicly available only in hard copy form. Publicly available docket materials are available either in the electronic docket at https:// www.regulations.gov, or, if only available in hard copy, at the OPP Regulatory Public Docket in Rm. S– 4400, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. The hours of operation of this Docket Facility are from 8:30 a.m. to 4 p.m., Monday through Friday, excluding legal holidays. The Docket Facility telephone number is (703) 305–5805. Eric Miederhoff, Special Review and Reregistration Division (7508P), Office of Pesticide Programs, Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460– 0001; telephone number: (703) 3478028; fax number: (703) 308-7070; email address: miederhoff.eric@epa.gov. FOR FURTHER INFORMATION CONTACT: SUPPLEMENTARY INFORMATION: E:\FR\FM\23APN1.SGM 23APN1

Agencies

[Federal Register Volume 73, Number 79 (Wednesday, April 23, 2008)]
[Notices]
[Pages 21941-21942]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E8-8797]


-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

[FRL-8556-5; Docket ID No. EPA-HQ-ORD-2008-0048]


Draft Toxicological Review of 2-Hexanone: In Support of the 
Summary Information in the Integrated Risk Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for 
external scientific peer review, will convene an independent panel of 
experts and organize and conduct an external peer-review meeting to 
review the external review draft document titled, ``Toxicological 
Review of 2-Hexanone: In Support of Summary Information on the 
Integrated Risk Information System (IRIS)'' (NCEA-S-2764). EPA 
previously announced the 60-day public comment period (ending April 28, 
2008) for the draft document in the Federal Register on March 4, 2008 
(73 FR 11408). EPA will consider public comments and recommendations 
from the expert panel meeting as EPA finalizes the draft document.
    The public comment period and the external peer-review meeting are 
separate processes that provide opportunities for all interested 
parties to comment on the document. EPA intends to forward public 
comments submitted in accordance with Federal Register (73 FR 11408) to 
Versar, Inc., for consideration by the external peer-review panel prior 
to the meeting.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination.
    Versar, Inc., invites the public to register to attend this meeting 
as observers. In addition, Versar, Inc., invites the public to give 
brief oral comments at the meeting regarding the draft document under 
review. The draft document and EPA's peer-review charge are available 
via the Internet on the National Center for Environmental Assessment's 
(NCEA) home page under the Recent Additions and the Data and 
Publications menus at https://www.epa.gov/ncea. When finalizing the 
draft document, EPA intends to consider Versar's report of the comments 
and recommendations from the external peer-review meeting and any 
public comments that EPA receives in accordance with 73 FR 11408, March 
4, 2008. Public comments that were submitted during the 60-day public 
comment period ending April 28, 2008 may be observed at https://
www.regulations.gov under Docket ID No. EPA-HQ-ORD-2008-0048.

DATES: The peer-review panel meeting will begin on May 22, 2008, at 9 
a.m. and end at 5 p.m. Register by May 16, 2008, if you wish to provide 
brief oral comments at the meeting.

ADDRESSES: The peer-review meeting will be held at the Courtyard by 
Marriott Crystal City, 2899 Jefferson Davis Highway, Arlington, VA 
22202. Versar, Inc., is organizing, convening, and conducting the peer-
review meeting. To attend the meeting, register by May 16, 2008, via 
the Internet at https://epa.versar.com/2hexanone/.
    The draft ``Toxicological Review of 2-Hexanone: In Support of 
Summary Information on the Integrated Risk Information System (IRIS)'' 
is available via the Internet on the National Center for Environmental 
Assessment's (NCEA) home page under the Recent Additions and the Data 
and Publications menus at https://www.epa.gov/ncea. A limited number of 
paper copies are available from the Information Management Staff, NCEA; 
telephone: 703-347-8561; facsimile: 703-347-8691. If you are requesting 
a paper copy, please provide your name, mailing address, and the 
document title. Copies are not available from Versar, Inc.

FOR FURTHER INFORMATION CONTACT: For information on the peer review 
meeting, contact Stephanie Sarraino, Versar, Inc.; telephone: 703-750-
3000 ext. 316; e-mail: ssarraino@versar.com.
    If you have questions about the document, contact Amanda S. Persad, 
IRIS Staff, National Center for Environmental Assessment (B-243-01), 
U.S. EPA, Research Triangle Park, NC, 27711; telephone: 919-541-9781; 
facsimile: 919-541-1818; e-mail: persad.amanda@epa.gov.

SUPPLEMENTARY INFORMATION:

I. Summary of Information About the Integrated Risk Information System 
(IRIS)

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at https://www.epa.gov/iris) contains 
qualitative and quantitative health effects information for more than 
500 chemical substances that may be used to support the first two steps 
(hazard identification and dose-

[[Page 21942]]

response evaluation) of a risk assessment process. When supported by 
available data, the database provides oral reference doses (RfDs) and 
inhalation reference concentrations (RfCs) for chronic health effects, 
and oral slope factors and inhalation unit risks for carcinogenic 
effects. Combined with specific exposure information, government and 
private entities can use IRIS data to help characterize public health 
risks of chemical substances in a site-specific situation and thereby 
support risk management decisions designed to protect public health.

II. Meeting Information

    Members of the public may attend the meeting as observers, and 
there will be a limited time for oral comments from the public. Please 
let Versar, Inc. know if you wish to make comments during the meeting 
by registering on the Web site at https://epa.versar.com/2hexanone/ and 
indicating your intent to make oral comments. Space is limited, and 
reservations will be accepted on a first-come, first-served basis.

    Dated: April 15, 2008.
Peter W. Preuss,
Director, National Center for Environmental Assessment.
 [FR Doc. E8-8797 Filed 4-22-08; 8:45 am]
BILLING CODE 6560-50-P
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