Availability of Two Interaction Profiles [Draft Documents], 21135-21136 [E8-8167]

Download as PDF Federal Register / Vol. 73, No. 76 / Friday, April 18, 2008 / Notices delegation does not apply to competition-related investigations. By direction of the Commission. Donald S. Clark, Secretary. [FR Doc. E8–8482 Filed 4–17–08; 8:45 am] BILLING CODE 6750–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Notice of Interest Rate on Overdue Debts Section 30.13 of the Department of Health and Human Services’ claims collection regulations (45 CFR Part 30) provides that the Secretary shall charge an annual rate of interest as fixed by the Secretary of the Treasury after taking into consideration private consumer rates of interest prevailing on the date that HHS becomes entitled to recovery. The rate generally cannot be lower than the Department of Treasury’s current value of funds rate or the applicable rate determined from the ‘‘Schedule of Certified Interest Rates with Range of Maturities.’’ This rate may be revised quarterly by the Secretary of the Treasury and shall be published quarterly by the Department of Health and Human Services in the Federal Register. The Secretary of the Treasury has certified a rate of 113⁄8% for the quarter ended March 31, 2008. This interest rate will remain in effect until such time as the Secretary of the Treasury notifies HHS of any change. Dated: April 14, 2008. Molly P. Dawson, Director, Office of Financial Policy and Reporting. [FR Doc. E8–8374 Filed 4–17–08; 8:45 am] BILLING CODE 4150–04–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Toxic Substances and Disease Registry [ATSDR–243] Availability of Two Interaction Profiles [Draft Documents] Agency for Toxic Substances and Disease Registry (ATSDR), Department of Health and Human Services (DHHS). ACTION: Notice of availability for public comments. pwalker on PROD1PC71 with NOTICES AGENCY: VerDate Aug<31>2005 17:38 Apr 17, 2008 Jkt 214001 SUMMARY: This notice announces the availability of two interaction profiles prepared by ATSDR for public comments [draft documents]. DATES: The interaction profiles will be available to the public on or about April 15, 2008. ADDRESSES: The documents will be available on ATSDR’s Web site at http:// www.atsdr.cdc.gov. FOR FURTHER INFORMATION CONTACT: Please submit comments regarding the information contained in the profiles to Dr. Hana Pohl, Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Mailstop F–32, 1600 Clifton Road, NE., Atlanta, Georgia 30333, telephone (888) 422–8737. SUPPLEMENTARY INFORMATION: ATSDR develops interaction profiles for hazardous substances found at the National Priority List (NPL) sites under Section 104(i)(3) and (5) of the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). This public law mandates that ATSDR assess whether or not adequate information on health effects is available for priority hazardous substances. Where such information is not available or under development, ATSDR shall, in cooperation with the National Toxicology Program, initiate a research program to determine these health effects. The act further directs that, where feasible, ATSDR shall develop methods to determine the health effects of these priority hazardous substances in combination with other substances commonly found with them. To carry out these legislative mandates, ATSDR has developed a chemical mixtures program. As part of the mixtures program, ATSDR developed a guidance manual that outlines the latest methods for mixtures health assessment. In addition, a series of documents called ‘‘interaction profiles’’ is being developed for certain priority mixtures that are of special concern to ATSDR. To recommend approaches for the exposure-based assessment of the potential hazard to public health, an interaction profile evaluates data on the toxicology of the whole priority mixture, if available, and on the joint toxic action of the chemicals in the mixture. The entire interaction profile development process is as follows: • ATSDR selects substances/ chemicals for development of interaction profiles through inter/intra agency communications collaboration and literature reviews. PO 00000 Frm 00041 Fmt 4703 Sfmt 4703 21135 • After the selection, a letter is sent to individuals and agencies on ATSDR’s mailing list providing notice of ATSDR’s intent to create an interaction profile. • A notice is posted in the Federal Register to inform the public of ATSDR’s intent to develop a particular interaction profile. • The draft interaction profile undergoes both internal and external peer review. • A Federal Register notice announces the release of the official draft for public comment. • ATSDR posts a link to the draft interaction profile on its Web site, giving the public an opportunity to provide comments. • ATSDR reviews all public comments and revises the draft, as appropriate, before issuing the final version. The following documents will be available to the public on or about April 15, 2008. Document 1 Interaction Profile for Carbon Monoxide, Formaldehyde, Methylene Chloride, Nitrogen Dioxide, and Tetrachloroethylene. Document 2 Interaction Profile for Chloroform, 1,1-Dichloroethylene, Trichloroethylene, and Vinyl Chloride. Document 1 evaluates a mixture of chemicals often found in indoor air based on the information regarding residential (i.e., background) exposures provided by the U.S. Environmental Protection Agency. Data on background exposures can be used for evaluations of total exposures in populations living around hazardous waste sites. Document 2 evaluates a mixture of volatile organic chemicals. This particular mixture was chosen as a subject for the interaction profile because these chemicals are among the top 10 chemicals found in water around hazardous waste sites. Consequently, they are also encountered in combinations. The two interaction profiles underwent external peer review. These documents were also reviewed by the ATSDR’s Interagency Workgroup on Mixtures. The documents will be available for public comments for 90 days. E:\FR\FM\18APN1.SGM 18APN1 21136 Federal Register / Vol. 73, No. 76 / Friday, April 18, 2008 / Notices Dated: April 11, 2008. Tim Hack, Deputy Director, Office of Policy, Planning and Evaluation, National Center for Environmental Health/Agency for Toxic Substances and Disease Registry. [FR Doc. E8–8167 Filed 4–17–08; 8:45 am] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Epidemiology of Carbapenemase-Producing Enterobacteriaceae in a Healthcare Setting, Potential Extramural Projects (PEP) 2008–R–24 In accordance with Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92–463), the Centers for Disease Control and Prevention (CDC) announces the aforementioned meeting. pwalker on PROD1PC71 with NOTICES Time and Date: 1 p.m.–2 p.m., May 15, 2008 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c)(4) and (6), Title 5 U.S.C., and the Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92–463. Matters to be Discussed: The meeting will include the review, discussion, and evaluation of ‘‘Epidemiology of Carbapenemase-Producing Enterobacteriaceae in a Healthcare Setting, PEP 2008–R–24.’’ Contact Person for More Information: Linda Shelton, Program Specialist, Coordinating Center for Health and Information Service, Office of the Director, CDC, 1600 Clifton Road, NE., Mailstop E21, Atlanta, GA 30333, Telephone (404) 498– 1194. The Director, Management Analysis and Services Office, has been delegated the authority to sign Federal Register notices pertaining to announcements of meetings and other committee management activities, for both CDC and the Agency for Toxic Substances and Disease Registry. Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Monitoring Hospitalizations and Outpatient Visits for Pneumonia and Other Non-Invasive Pneumonococcal Diseases by Using National Databases, Potential Extramural Project (PEP) 2008–R–17 BILLING CODE 4163–70–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Survey of Community Support Interventions for Mammography Screenings, Potential Extramural Project (PEP) 2008–R–13 In accordance with Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92–463), the Centers for Disease Control and Prevention (CDC) announces the aforementioned meeting. Time and Date: 1 p.m.–2:30 p.m., May 19, 2008 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c)(4) and (6), Title 5 U.S.C., and the Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92–463. Matters to be Discussed: The meeting will include the review, discussion, and evaluation of ‘‘Monitoring Hospitalizations and Outpatient Visits for Pneumonia and other Non-Invasive Pneumonococcal Diseases by Using National Databases, PEP 2008–R–17.’’ Contact Person for More Information: Linda Shelton, Program Specialist, Coordinating Center for Health and Information Service, Office of the Director, CDC, 1600 Clifton Road, NE., Mailstop E21, Atlanta, GA 30333, Telephone (404) 498– 1194. The Director, Management Analysis and Services Office, has been delegated the authority to sign Federal Register notices pertaining to announcements of meetings and other committee management activities, for both CDC and the Agency for Toxic Substances and Disease Registry. Dated: April 10, 2008. Elaine L. Baker, Director, Management Analysis and Services Office, Centers for Disease Control and Prevention. [FR Doc. E8–8356 Filed 4–17–08; 8:45 am] BILLING CODE 4163–18–P In accordance with Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92–463), the Centers for Disease Control and Prevention (CDC) announces the aforementioned meeting. Time and Date: 1 p.m.–2:30 p.m., May 20, 2008 (Closed). Place: Teleconference. Status: The meeting will be closed to the public in accordance with provisions set forth in Section 552b(c)(4) and (6), Title 5 U.S.C., and the Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92–463. Matters to be Discussed: The meeting will include the review, discussion, and evaluation of ‘‘Survey of Community Support Interventions for Mammography Screenings, PEP 2008–R–13.’’ Contact Person for More Information: Linda Shelton, Program Specialist, Coordinating Center for Health and Information Service, Office of the Director, CDC, 1600 Clifton Road, NE., Mailstop E21, Atlanta, GA 30333, Telephone (404) 498– 1194. The Director, Management Analysis and Services Office, has been delegated the authority to sign Federal Register notices pertaining to announcements of meetings and other committee management activities, for both CDC and the Agency for Toxic Substances and Disease Registry. Dated: April 10, 2008. Elaine L. Baker, Director, Management Analysis and Services Office, Centers for Disease Control and Prevention. [FR Doc. E8–8357 Filed 4–17–08; 8:45 am] BILLING CODE 4163–18–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): The Effect of Prenatal Bleeding on Pregnancy Outcomes in Women With a Previously Undiagnosed Bleeding Disorder, Potential Extramural Project (PEP) 2008–R–27 Dated: April 10, 2008. Elaine L. Baker, Director, Management Analysis and Services Office, Centers for Disease Control and Prevention. [FR Doc. E8–8355 Filed 4–17–08; 8:45 am] BILLING CODE 4163–18–P In accordance with Section 10(a)(2) of the Federal Advisory Committee Act VerDate Aug<31>2005 17:38 Apr 17, 2008 Jkt 214001 PO 00000 Frm 00042 Fmt 4703 Sfmt 4703 E:\FR\FM\18APN1.SGM 18APN1

Agencies

[Federal Register Volume 73, Number 76 (Friday, April 18, 2008)]
[Notices]
[Pages 21135-21136]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E8-8167]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[ATSDR-243]


Availability of Two Interaction Profiles [Draft Documents]

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (DHHS).

ACTION: Notice of availability for public comments.

-----------------------------------------------------------------------

SUMMARY: This notice announces the availability of two interaction 
profiles prepared by ATSDR for public comments [draft documents].

DATES: The interaction profiles will be available to the public on or 
about April 15, 2008.

ADDRESSES: The documents will be available on ATSDR's Web site at 
http://www.atsdr.cdc.gov.

FOR FURTHER INFORMATION CONTACT: Please submit comments regarding the 
information contained in the profiles to Dr. Hana Pohl, Division of 
Toxicology and Environmental Medicine, Agency for Toxic Substances and 
Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta, 
Georgia 30333, telephone (888) 422-8737.

SUPPLEMENTARY INFORMATION: ATSDR develops interaction profiles for 
hazardous substances found at the National Priority List (NPL) sites 
under Section 104(i)(3) and (5) of the Comprehensive Environmental 
Response, Compensation, and Liability Act of 1980 (CERCLA). This public 
law mandates that ATSDR assess whether or not adequate information on 
health effects is available for priority hazardous substances. Where 
such information is not available or under development, ATSDR shall, in 
cooperation with the National Toxicology Program, initiate a research 
program to determine these health effects. The act further directs 
that, where feasible, ATSDR shall develop methods to determine the 
health effects of these priority hazardous substances in combination 
with other substances commonly found with them.
    To carry out these legislative mandates, ATSDR has developed a 
chemical mixtures program. As part of the mixtures program, ATSDR 
developed a guidance manual that outlines the latest methods for 
mixtures health assessment. In addition, a series of documents called 
``interaction profiles'' is being developed for certain priority 
mixtures that are of special concern to ATSDR. To recommend approaches 
for the exposure-based assessment of the potential hazard to public 
health, an interaction profile evaluates data on the toxicology of the 
whole priority mixture, if available, and on the joint toxic action of 
the chemicals in the mixture.
    The entire interaction profile development process is as follows:
     ATSDR selects substances/chemicals for development of 
interaction profiles through inter/intra agency communications 
collaboration and literature reviews.
     After the selection, a letter is sent to individuals and 
agencies on ATSDR's mailing list providing notice of ATSDR's intent to 
create an interaction profile.
     A notice is posted in the Federal Register to inform the 
public of ATSDR's intent to develop a particular interaction profile.
     The draft interaction profile undergoes both internal and 
external peer review.
     A Federal Register notice announces the release of the 
official draft for public comment.
     ATSDR posts a link to the draft interaction profile on its 
Web site, giving the public an opportunity to provide comments.
     ATSDR reviews all public comments and revises the draft, 
as appropriate, before issuing the final version.
    The following documents will be available to the public on or about 
April 15, 2008.

Document 1

    Interaction Profile for Carbon Monoxide, Formaldehyde, Methylene 
Chloride, Nitrogen Dioxide, and Tetrachloroethylene.

Document 2

    Interaction Profile for Chloroform, 1,1-Dichloroethylene, 
Trichloroethylene, and Vinyl Chloride.
    Document 1 evaluates a mixture of chemicals often found in indoor 
air based on the information regarding residential (i.e., background) 
exposures provided by the U.S. Environmental Protection Agency. Data on 
background exposures can be used for evaluations of total exposures in 
populations living around hazardous waste sites.
    Document 2 evaluates a mixture of volatile organic chemicals. This 
particular mixture was chosen as a subject for the interaction profile 
because these chemicals are among the top 10 chemicals found in water 
around hazardous waste sites. Consequently, they are also encountered 
in combinations.
    The two interaction profiles underwent external peer review. These 
documents were also reviewed by the ATSDR's Interagency Workgroup on 
Mixtures.
    The documents will be available for public comments for 90 days.


[[Page 21136]]


    Dated: April 11, 2008.
Tim Hack,
Deputy Director, Office of Policy, Planning and Evaluation, National 
Center for Environmental Health/Agency for Toxic Substances and Disease 
Registry.
[FR Doc. E8-8167 Filed 4-17-08; 8:45 am]
BILLING CODE 4163-70-P