Draft Toxicological Review of 1,2,3-Trichloropropane: In Support of the Summary Information in the Integrated Risk Information System (IRIS), 64626-64627 [E7-22444]

Download as PDF 64626 Federal Register / Vol. 72, No. 221 / Friday, November 16, 2007 / Notices biomagnify appreciably in aquatic food webs, the compound does bioconcentrate in aquatic organisms to a significant extent. Also, there is direct evidence (measured residues) that endosulfan bioaccumulates in terrestrial systems and indirect evidence (modeling) that endosulfan has a significant potential to biomagnify in certain terrestrial food webs. In addition, EPA continues to be concerned about endosulfan’s volatility and its ability to migrate to sites distant from use areas, such as the Arctic, through various environmental media (air, water, and sediment). EPA is providing an opportunity, through this notice, for interested parties to comment on the Agency’s updated human health and ecological effects assessments for endosulfan. Risks of concern associated with the use of endosulfan are: (1) Occupational handler risks for many use scenarios, even with maximum PPE and engineering controls; (2) risk to aquatic and terrestrial organisms; and (3) potential for significant adverse effects to vulnerable populations and ecosystems, based on the ability for endosulfan and its sulfate degradate to migrate to sites distant from use areas. In addition, the Agency is soliciting public comment on EPA’s analysis of endosulfan usage information since the 2002 RED, and its preliminary determinations regarding endosulfan’s importance to growers and availability of alternatives. All comments should be submitted using the methods inADDRESSES, and must be received by EPA on or before the closing date. Comments and proposals will become part of the Agency Docket for endosulfan. Comments received after the close of the comment period will be marked ‘‘late.’’ EPA is not required to consider these late comments. mstockstill on PROD1PC66 with NOTICES B. What is the Agency’s Authority for Taking this Action? Section 4(g)(2) of FIFRA, as amended, directs that, after submission of all data concerning a pesticide active ingredient, ‘‘the Administrator shall determine whether pesticides containing such active ingredient are eligible for reregistration,’’ before calling in product-specific data on individual enduse products and either reregistering products or taking other ‘‘appropriate regulatory action.’’ List of Subjects Environmental protection, Pesticides and pests. VerDate Aug<31>2005 21:48 Nov 15, 2007 Jkt 214001 Dated: November 8, 2007. Peter Caulkins, Acting Director, Special Review and Reregistration Division, Office of Pesticide Programs. [FR Doc. E7–22385 Filed 11–15–07; 8:45 am] BILLING CODE 6560–50–S ENVIRONMENTAL PROTECTION AGENCY [FRL–8495–5; Docket ID No. EPA–HQ–ORD– 2007–1083] Draft Toxicological Review of 1,2,3Trichloropropane: In Support of the Summary Information in the Integrated Risk Information System (IRIS) Environmental Protection Agency (EPA). ACTION: Notice of Public Comment Period. AGENCY: SUMMARY: EPA is announcing a public comment period for the external review draft document titled, ‘‘Toxicological Review of 1,2,3-Trichloropropane: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ (NCEA–S–1669). The EPA intends to consider comments and recommendations from the public and the expert panel meeting, which will be scheduled at a later date and announced in the Federal Register, when EPA finalizes the draft document. The public comment period will provide opportunities for all interested parties to comment on the document. EPA intends to forward public comments, submitted in accordance with this notice, to the external peer-review panel prior to the workshop for their consideration. EPA is releasing this draft document solely for the purpose of predissemination public review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination. The draft document is available via the Internet on NCEA’s home page under the Recent Additions and the Data and Publications menus at www.epa.gov/ncea. When finalizing the draft document, EPA intends to consider any public comments that EPA receives in accordance with this notice. DATES: The public comment period begins November 16, 2007, and ends January 15, 2008. Technical comments should be in writing and must be received by EPA by January 15, 2008. EPA intends to submit comments from the public received by this date for PO 00000 Frm 00053 Fmt 4703 Sfmt 4703 consideration by the external peerreview panel. ADDRESSES: The draft ‘‘Toxicological Review of 1,2,3-Trichloropropane: In Support of Summary Information on the Integrated Risk Information System (IRIS)’’ is available via the Internet on the National Center for Environmental Assessment’s (NCEA) home page under the Recent Additions and the Data and Publications menus at www.epa.gov/ ncea. A limited number of paper copies are available from the Technical Information Staff, NCEA–W; telephone: 202–564–3261; facsimile: 202–565– 0050. If you are requesting a paper copy, please provide your name, mailing address, and the document title. Comments may be submitted electronically via www.regulations.gov, by mail, by facsimile, or by hand delivery/courier. Please follow the detailed instructions as provided in the SUPPLEMENTARY INFORMATION section of this notice. FOR FURTHER INFORMATION CONTACT: For information on the public comment period, contact the Office of Environmental Information Docket; telephone: 202–566–1752; facsimile: 202–566–1753; or e-mail: ORD.Docket@epa.gov. If you have questions about the document, contact Martin Gehlhaus, IRIS Staff, National Center for Environmental Assessment, (8601D), U.S. EPA, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone: 202–564–1596; facsimile: 202–565– 0075; gehlhaus.martin@epa.gov (e-mail). SUPPLEMENTARY INFORMATION: I. Summary of Information About the Integrated Risk Information System (IRIS) IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 500 chemical substances that may be used to support the first two steps (hazard identification and doseresponse evaluation) of a risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with specific exposure information, government and private entities can use IRIS data to help characterize public E:\FR\FM\16NON1.SGM 16NON1 Federal Register / Vol. 72, No. 221 / Friday, November 16, 2007 / Notices mstockstill on PROD1PC66 with NOTICES health risks of chemical substances in a site-specific situation and thereby support risk management decisions designed to protect public health. II. How To Submit Technical Comments to the Docket at www.regulations.gov Submit your comments, identified by Docket ID No. EPA–HQ–ORD–2007– 1083 by one of the following methods: • www.regulations.gov: Follow the on-line instructions for submitting comments. • E-mail: ORD.Docket@epa.gov. • Fax: 202–566–1753. • Mail: Office of Environmental Information (OEI) Docket (Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202–566–1752. • Hand Delivery: The OEI Docket is located in the EPA Headquarters Docket Center, EPA West Building, Room 3334, 1301 Constitution Ave., NW., Washington, DC. The EPA Docket Center Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is 202–566–1744. Such deliveries are only accepted during the docket’s normal hours of operation, and special arrangements should be made for deliveries of boxed information. If you provide comments by e-mail or hand delivery, please submit one unbound original with pages numbered consecutively, and three copies of the comments. For attachments, provide an index, number pages consecutively with the comments, and submit an unbound original and three copies. Instructions: Direct your comments to Docket ID No. EPA–HQ–ORD–2007– 1083. Please ensure that your comments are submitted within the specified comment period. Comments received after the closing date will be marked ‘‘late,’’ and may only be considered if time permits. It is EPA’s policy to include all comments it receives in the public docket without change and to make the comments available online at www.regulations.gov, including any personal information provided, unless a comment includes information claimed to be confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through www.regulations.gov or e-mail. The www.regulations.gov Web site is an ‘‘anonymous access’’ system, which means EPA will not know your identity or contact information unless you provide it in the body of your VerDate Aug<31>2005 21:48 Nov 15, 2007 Jkt 214001 comment. If you send an e-mail comment directly to EPA without going through www.regulations.gov, your email address will be automatically captured and included as part of the comment that is placed in the public docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CD–ROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form of encryption, and be free of any defects or viruses. For additional information about EPA’s public docket, visit the EPA Docket Center homepage at www.epa.gov/epahome/dockets.htm. Docket: All documents in the docket are listed in the www.regulations.gov index. Although listed in the index, some information is not publicly available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other material, such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in www.regulations.gov or in hard copy at the OEI Docket in the EPA Headquarters Docket Center. Dated: November 2, 2007. Rebecca Clark, Deputy Director, National Center for Environmental Assessment. [FR Doc. E7–22444 Filed 11–15–07; 8:45 am] BILLING CODE 6560–50–P 64627 SUPPLEMENTARY INFORMATION: Publication of the Performance Review Board (PRB) is required by 5 U.S.C. section 4314(c)(4). The PRB reviews and evaluates the initial appraisal of a senior executive’s performance by the supervisor, and makes written recommendations regarding performance ratings, performance awards, potential Presidential Rank Award nominees, and performancebased pay adjustments to the Chair. The Board shall consist of at least three voting members. When evaluating a career appointee’s initial appraisal or recommending a career appointee for a performance award, more than half of the members must be Senor Executive Service career appointees. The names and titles of the PRB members and alternates are as follows: Anthony J. Kaminski, Chief Operating Officer (Chairperson) John Czajkowski, Deputy Associate Director, Center for Program Studies, Office of Personnel Management (Member); Rita Franklin, Deputy Director, Office of Human Capital Management, Department of Energy (Member); Carlton M. Hadden, Director, Office of Federal Operations (Alternate); Olophius Perry, Director, Los Angeles District Office (Member); Gwendolyn Young Reams, Associate General Counsel for Litigation Management (Member); and R.J. Ruff, Director, Houston District Office (Alternate). Signed at Washington, DC, on this 8th day of November 2007. For the Commission. Naomi C. Earp, Chair. [FR Doc. E7–22388 Filed 11–15–07; 8:45 am] BILLING CODE 6570–01–P EQUAL EMPLOYMENT OPPORTUNITY COMMISSION SES Performance Review Board U.S. Equal Employment Opportunity Commission (EEOC). ACTION: Notice of membership of the EEOC Performance Review Board. AGENCY: SUMMARY: Notice is hereby given of the appointment of members to the EEOC Performance Review Board. DATES: Membership is effective on the date of this notice. FOR FURTHER INFORMATION CONTACT: Angelica E. Ibarguen, Chief Human Capital Officer, Office of Human Resources, U.S. Equal Employment Opportunity Commission, 1801 L Street, NW., Washington, DC 20507, (202) 663– 4306. PO 00000 Frm 00054 Fmt 4703 Sfmt 4703 EXPORT-IMPORT BANK OF THE UNITED STATES Sunshine Act Meeting Notice of a Partially Open Meeting of the Board of Directors of the Export-Import Bank of the United States. TIME AND PLACE: Tuesday, November 20, 2007 at 9:30 a.m. The meeting will be held at Ex-Im Bank in room 1143, 811 Vermont Avenue, NW., Washington, DC 20571. 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[Federal Register Volume 72, Number 221 (Friday, November 16, 2007)]
[Notices]
[Pages 64626-64627]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E7-22444]


-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

 [FRL-8495-5; Docket ID No. EPA-HQ-ORD-2007-1083]


Draft Toxicological Review of 1,2,3-Trichloropropane: In Support 
of the Summary Information in the Integrated Risk Information System 
(IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of Public Comment Period.

-----------------------------------------------------------------------

SUMMARY: EPA is announcing a public comment period for the external 
review draft document titled, ``Toxicological Review of 1,2,3-
Trichloropropane: In Support of Summary Information on the Integrated 
Risk Information System (IRIS)'' (NCEA-S-1669). The EPA intends to 
consider comments and recommendations from the public and the expert 
panel meeting, which will be scheduled at a later date and announced in 
the Federal Register, when EPA finalizes the draft document. The public 
comment period will provide opportunities for all interested parties to 
comment on the document. EPA intends to forward public comments, 
submitted in accordance with this notice, to the external peer-review 
panel prior to the workshop for their consideration.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination public review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination.
    The draft document is available via the Internet on NCEA's home 
page under the Recent Additions and the Data and Publications menus at 
www.epa.gov/ncea. When finalizing the draft document, EPA intends to 
consider any public comments that EPA receives in accordance with this 
notice.

DATES: The public comment period begins November 16, 2007, and ends 
January 15, 2008. Technical comments should be in writing and must be 
received by EPA by January 15, 2008. EPA intends to submit comments 
from the public received by this date for consideration by the external 
peer-review panel.

ADDRESSES: The draft ``Toxicological Review of 1,2,3-Trichloropropane: 
In Support of Summary Information on the Integrated Risk Information 
System (IRIS)'' is available via the Internet on the National Center 
for Environmental Assessment's (NCEA) home page under the Recent 
Additions and the Data and Publications menus at www.epa.gov/ncea. A 
limited number of paper copies are available from the Technical 
Information Staff, NCEA-W; telephone: 202-564-3261; facsimile: 202-565-
0050. If you are requesting a paper copy, please provide your name, 
mailing address, and the document title.
    Comments may be submitted electronically via www.regulations.gov, 
by mail, by facsimile, or by hand delivery/courier. Please follow the 
detailed instructions as provided in the SUPPLEMENTARY INFORMATION 
section of this notice.

FOR FURTHER INFORMATION CONTACT: For information on the public comment 
period, contact the Office of Environmental Information Docket; 
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail: 
ORD.Docket@epa.gov.
    If you have questions about the document, contact Martin Gehlhaus, 
IRIS Staff, National Center for Environmental Assessment, (8601D), U.S. 
EPA, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone: 
202-564-1596; facsimile: 202-565-0075; gehlhaus.martin@epa.gov (e-
mail).

SUPPLEMENTARY INFORMATION: 

I. Summary of Information About the Integrated Risk Information System 
(IRIS)

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at www.epa.gov/iris) contains qualitative 
and quantitative health effects information for more than 500 chemical 
substances that may be used to support the first two steps (hazard 
identification and dose-response evaluation) of a risk assessment 
process. When supported by available data, the database provides oral 
reference doses (RfDs) and inhalation reference concentrations (RfCs) 
for chronic health effects, and oral slope factors and inhalation unit 
risks for carcinogenic effects. Combined with specific exposure 
information, government and private entities can use IRIS data to help 
characterize public

[[Page 64627]]

health risks of chemical substances in a site-specific situation and 
thereby support risk management decisions designed to protect public 
health.

II. How To Submit Technical Comments to the Docket at 
www.regulations.gov

    Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2007-
1083 by one of the following methods:
     www.regulations.gov: Follow the on-line instructions for 
submitting comments.
     E-mail: ORD.Docket@epa.gov.
     Fax: 202-566-1753.
     Mail: Office of Environmental Information (OEI) Docket 
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
     Hand Delivery: The OEI Docket is located in the EPA 
Headquarters Docket Center, EPA West Building, Room 3334, 1301 
Constitution Ave., NW., Washington, DC. The EPA Docket Center Public 
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the Public 
Reading Room is 202-566-1744. Such deliveries are only accepted during 
the docket's normal hours of operation, and special arrangements should 
be made for deliveries of boxed information.
    If you provide comments by e-mail or hand delivery, please submit 
one unbound original with pages numbered consecutively, and three 
copies of the comments. For attachments, provide an index, number pages 
consecutively with the comments, and submit an unbound original and 
three copies.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2007-1083. Please ensure that your comments are submitted within the 
specified comment period. Comments received after the closing date will 
be marked ``late,'' and may only be considered if time permits. It is 
EPA's policy to include all comments it receives in the public docket 
without change and to make the comments available online at 
www.regulations.gov, including any personal information provided, 
unless a comment includes information claimed to be confidential 
Business Information (CBI) or other information whose disclosure is 
restricted by statute. Do not submit information that you consider to 
be CBI or otherwise protected through www.regulations.gov or e-mail. 
The www.regulations.gov Web site is an ``anonymous access'' system, 
which means EPA will not know your identity or contact information 
unless you provide it in the body of your comment. If you send an e-
mail comment directly to EPA without going through www.regulations.gov, 
your e-mail address will be automatically captured and included as part 
of the comment that is placed in the public docket and made available 
on the Internet. If you submit an electronic comment, EPA recommends 
that you include your name and other contact information in the body of 
your comment and with any disk or CD-ROM you submit. If EPA cannot read 
your comment due to technical difficulties and cannot contact you for 
clarification, EPA may not be able to consider your comment. Electronic 
files should avoid the use of special characters, any form of 
encryption, and be free of any defects or viruses. For additional 
information about EPA's public docket, visit the EPA Docket Center 
homepage at www.epa.gov/epahome/dockets.htm.
    Docket: All documents in the docket are listed in the 
www.regulations.gov index. Although listed in the index, some 
information is not publicly available, e.g., CBI or other information 
whose disclosure is restricted by statute. Certain other material, such 
as copyrighted material, will be publicly available only in hard copy. 
Publicly available docket materials are available either electronically 
in www.regulations.gov or in hard copy at the OEI Docket in the EPA 
Headquarters Docket Center.

    Dated: November 2, 2007.
Rebecca Clark,
Deputy Director, National Center for Environmental Assessment.
 [FR Doc. E7-22444 Filed 11-15-07; 8:45 am]
BILLING CODE 6560-50-P