Agency Forms Undergoing Paperwork Reduction Act Review, 64229-64230 [E7-22315]
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64229
Federal Register / Vol. 72, No. 220 / Thursday, November 15, 2007 / Notices
Background and Brief Description
In October, 2006, CDC recommended
specific strategies to reduce
transmission of multi-drug resistant
organisms, including MRSA, in U.S.
hospitals. Currently detailed data on
ongoing MRSA prevention efforts at
hospitals reporting to CDC surveillance
systems is unknown. CDC has
developed a survey to assess MRSA
prevention programs in place at health
care facilities reporting MRSA infection
data to CDC through established
surveillance systems. In this project,
infection control practitioners in all
hospitals that participate in the MRSA
portion of the Active Bacterial Core
Surveillance System will be surveyed
electronically three times. There will be
an initial baseline survey and then two
follow-up surveys, each a year apart.
The surveys will determine if changes
in infection control practice correlate
with changes in rates of MRSA
infections. The proposed survey will
provide data that can be used to assess
progress toward achieving CDC’s Health
Protection Goals. The survey will also
provide data on facility-based MRSA
Number of
respondents
Respondents
Infection Control Practitioners ...................................................................................
Dated: November 8, 2007.
Maryam I. Daneshvar,
Acting Reports Clearance Officer, Centers for
Disease Control and Prevention.
[FR Doc. E7–22314 Filed 11–14–07; 8:45 am]
BILLING CODE 4163–18–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Disease Control and
Prevention
[30Day–08–0728]
Agency Forms Undergoing Paperwork
Reduction Act Review
The Centers for Disease Control and
Prevention (CDC) publishes a list of
information collection requests under
review by the Office of Management and
Budget (OMB) in compliance with the
Paperwork Reduction Act (44 U.S.C.
Chapter 35). To request a copy of these
requests, call the CDC Reports Clearance
Officer at (404) 639–5960 or send an email to omb@cdc.gov. Send written
comments to CDC Desk Officer, Office of
Management and Budget, Washington,
DC or by fax to (202) 395–6974. Written
comments should be received within 30
days of this notice.
pwalker on PROD1PC71 with NOTICES
Proposed Project
The National Electronic Disease
Surveillance System (NEDSS)—
Extension—National Center for Public
Health Informatics (NCPHI), Centers for
Disease Control and Prevention (CDC).
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19:50 Nov 14, 2007
Jkt 214001
prevention policies and procedures that
may affect MRSA infection rates. These
results will inform CDC in the
prevention and control of MRSA.
This proposed project supports CDC’s
Goal of ‘‘Healthy People in Healthy
Places’’ and its Strategic Goal to
‘‘Increase the number of health care
institutions that comply with evidence
based guidelines for infection control.’’
There is no cost to respondents other
than their time to complete the survey.
The total estimated annualized burden
hours are 105 hours.
210
Background and Brief Description
CDC is responsible for the
dissemination of nationally notifiable
diseases information and for monitoring
and reporting the impact of epidemic
influenza on mortality, Public Health
Services Act (42 U.S.C. 241). Since
April 1984, CDC Epidemiology Program
Office (EPO) has been working with the
Council of State and Territorial
Epidemiologists (CSTE) to demonstrate
the efficiency and effectiveness of
computer transmission of surveillance
data between CDC and the state health
departments.
By 1989, all 50 states were using this
computerized disease surveillance
system, which was then renamed the
National Electronic
Telecommunications System for
Surveillance (NETSS) to reflect its
national scope (OMB numbers 0920–
0447 and 0920–0007).
Beginning in 1999, CDC,
Epidemiology Program Office (EPO)
worked with CSTE, state and local
public health system staff, and other
CDC disease prevention and control
program staff to identify information
categories and information technology
standards to support integrated disease
surveillance. That effort is now focused
on development and completion of the
National Electronic Disease Surveillance
System (NEDSS), coordinated by CDC’s
National Center for Public Health
Informatics, Division of Integrated
Surveillance Systems and Services
(DISSS).
States will continue to use portions of
NETSS to transmit data to CDC. One of
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Frm 00039
Fmt 4703
Sfmt 4703
Number of
responses per
respondent
Average burden
per response
(in hours)
1
30/60
the reasons for providing NETSS to
NEDSS data mapping is to identify what
data elements in NETSS correspond to
data elements in NEDSS. Those
elements mapped from NETSS to
NEDSS were collected in OMB number
0920–0007.
NEDSS will electronically integrate
and link together a wide variety of
surveillance activities and will facilitate
more accurate and timely reporting of
disease information to CDC and state
and local health departments.
Consistent with recommendations
supported by our state and local
surveillance partners and described in
the 1995 report, Integrating Public
Health Information and Surveillance
Systems, NEDSS includes data
standards, an internet based
communications infrastructure built on
industry standards, and policy-level
agreements on data access, sharing,
burden reduction, and protection of
confidentiality.
To support NEDSS, CDC has
developed an information system, the
NEDSS Base System (NBS), which uses
NEDSS technical and information
standards. The NBS is currently
deployed to 16 states, including AL, AR,
ID, MD, ME, MT, NE, NM, NV, RI, SC,
TN, TX, VA, VT, and WY.
CDC is requesting a three-year OMB
clearance extension of collecting the
NEDSS data. There are no costs to
respondents other than their time. The
average total annualized burden for the
Weekly Morbidity Reports and the
Annual Summary Report is 9,384 hours.
E:\FR\FM\15NON1.SGM
15NON1
64230
Federal Register / Vol. 72, No. 220 / Thursday, November 15, 2007 / Notices
ESTIMATED ANNUALIZED BURDEN HOURS
Number of
responses per
respondent
Average burden
per response
(in hours)
50
5
2
52
52
52
3
1.5
3
50
5
2
1
1
1
Number of
respondents
Respondents
Weekly Reporting
States .........................................................................................................................................
Territories ...................................................................................................................................
Cities ..........................................................................................................................................
Annual Reporting
States .........................................................................................................................................
Territories ...................................................................................................................................
Cities ..........................................................................................................................................
Dated: November 8, 2007.
Maryam I. Daneshvar,
Acting Reports Clearance Officer, Centers for
Disease Control and Prevention.
[FR Doc. E7–22315 Filed 11–14–07; 8:45 am]
BILLING CODE 4163–18–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Government-Owned Inventions;
Availability for Licensing
National Institutes of Health,
Public Health Service, HHS.
AGENCY:
ACTION:
Notice.
SUMMARY: The inventions listed below
are owned by an agency of the U.S.
Government and are available for
licensing in the U.S. in accordance with
35 U.S.C. 207 to achieve expeditious
commercialization of results of
federally-funded research and
development. Foreign patent
applications are filed on selected
inventions to extend market coverage
for companies and may also be available
for licensing.
Licensing information and
copies of the U.S. patent applications
listed below may be obtained by writing
to the indicated licensing contact at the
Office of Technology Transfer, National
Institutes of Health, 6011 Executive
Boulevard, Suite 325, Rockville,
Maryland 20852–3804; telephone: 301/
496–7057; fax: 301/402–0220. A signed
Confidential Disclosure Agreement will
be required to receive copies of the
patent applications.
pwalker on PROD1PC71 with NOTICES
ADDRESSES:
VerDate Aug<31>2005
19:50 Nov 14, 2007
Jkt 214001
Human T-box Transcription Factor
Brachyury as a Target for Cancer
Immunotherapy: Identification of
Epitopes of Human Brachyury as
Targets for T-cell Mediated Lysis of
Tumors
Description of Technology:
Identification of tumor antigens is
essential in advancing immune-based
therapeutic interventions in cancer.
Transcription factors that control
mesoderm have been implicated in
tumor cell invasion and metastasis.
Brachyury, a member of the T-box
transcription factor family, is a highly
conserved protein and a fundamental
player in mesoderm (epithelial-tomesenchymal transition, i.e. EMT)
specification in multicellular organisms.
This invention describes the
identification of the human
transcription factor Brachyury as a
novel target for cancer immunotherapy
for the treatment of several tumors such
as tumors of lung, intestine, stomach,
kidney, bladder, uterus, ovary, and
testis, and chronic lymphocytic
leukemia. This is the first demonstration
that (a) a T-box transcription factor and
(b) a molecule implicated in
mesodermal development (EMT) can be
a potential target for human T-cell
mediated cancer immunotherapy.
Applications:
1. Brachyury can be targeted for
cancer immunotherapy.
2. Epitopes of the Brachyury protein
that could be used to expand human Tlymphocytes for T-cell mediated lysis of
tumors.
3. The technology can be developed
as a cancer vaccine.
Advantages:
1. This technology can be delivered
with the U.S. government owned fowl
pox vector.
2. In vitro proof of concept data are
available.
Benefits: This is the first
demonstration that (a) a T-box
transcription factor and (b) a molecule
PO 00000
Frm 00040
Fmt 4703
Sfmt 4703
16
10
16
implicated in mesodermal development
(EMT) can be a potential target for
human T-cell mediated cancer
immunotherapy. This technology has
the potential of becoming a successful
therapy for metastatic cancers.
Inventors: Jeffrey Schlom, et al. (NCI,
CCR, LTIB)
Development Status: In vivo studies
are ongoing.
Relevant Publication: C Palena, DE
Polev, KY Tsang, RI Fernando, M
Litzinger, LL Krukovskaya, AV
Baranova, AP Kozlov, J Schlom. The
human T-box mesodermal transcription
factor Brachyury is a candidate target for
T-cell-mediated cancer immunotherapy.
Clin Cancer Res. 2007 Apr
15;13(8):2471–2478.
Patent Status: U.S. Provisional
Application filed 28 Feb 2007 (HHS
Reference No. E–074–2007/0–US–01).
Licensing Status: This technology is
available for licensing under an
exclusive or non-exclusive patent
license.
Licensing Contact: Michelle Booden,
PhD.; 301/451–7337;
boodenm@mail.nih.gov.
Collaborative Research Opportunity:
The National Cancer Institute, Center for
Cancer Research, Laboratory of Tumor
Immunology and Biology is seeking
statements of capability or interest from
parties interested in collaborative
research to further develop, evaluate, or
commercialize cancer vaccines aimed at
targeting Brachyury. Please contact John
D. Hewes, PhD. at 301–435–3121 or
hewesj@mail.nih.gov for more
information.
Diagnostic Ovarian Cancer Biomarkers
Description of Technology: Ovarian
cancer is one of the most common
malignancies. Warning symptoms
generally do not occur until the tumor
has already spread beyond the ovary. As
a result, patients are diagnosed with
advanced stages of ovarian cancer and
their prognosis is poor. Five year
E:\FR\FM\15NON1.SGM
15NON1
]]>Agencies
[Federal Register Volume 72, Number 220 (Thursday, November 15, 2007)]
[Notices]
[Pages 64229-64230]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E7-22315]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[30Day-08-0728]
Agency Forms Undergoing Paperwork Reduction Act Review
The Centers for Disease Control and Prevention (CDC) publishes a
list of information collection requests under review by the Office of
Management and Budget (OMB) in compliance with the Paperwork Reduction
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call
the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail
to omb@cdc.gov. Send written comments to CDC Desk Officer, Office of
Management and Budget, Washington, DC or by fax to (202) 395-6974.
Written comments should be received within 30 days of this notice.
Proposed Project
The National Electronic Disease Surveillance System (NEDSS)--
Extension--National Center for Public Health Informatics (NCPHI),
Centers for Disease Control and Prevention (CDC).
Background and Brief Description
CDC is responsible for the dissemination of nationally notifiable
diseases information and for monitoring and reporting the impact of
epidemic influenza on mortality, Public Health Services Act (42 U.S.C.
241). Since April 1984, CDC Epidemiology Program Office (EPO) has been
working with the Council of State and Territorial Epidemiologists
(CSTE) to demonstrate the efficiency and effectiveness of computer
transmission of surveillance data between CDC and the state health
departments.
By 1989, all 50 states were using this computerized disease
surveillance system, which was then renamed the National Electronic
Telecommunications System for Surveillance (NETSS) to reflect its
national scope (OMB numbers 0920-0447 and 0920-0007).
Beginning in 1999, CDC, Epidemiology Program Office (EPO) worked
with CSTE, state and local public health system staff, and other CDC
disease prevention and control program staff to identify information
categories and information technology standards to support integrated
disease surveillance. That effort is now focused on development and
completion of the National Electronic Disease Surveillance System
(NEDSS), coordinated by CDC's National Center for Public Health
Informatics, Division of Integrated Surveillance Systems and Services
(DISSS).
States will continue to use portions of NETSS to transmit data to
CDC. One of the reasons for providing NETSS to NEDSS data mapping is to
identify what data elements in NETSS correspond to data elements in
NEDSS. Those elements mapped from NETSS to NEDSS were collected in OMB
number 0920-0007.
NEDSS will electronically integrate and link together a wide
variety of surveillance activities and will facilitate more accurate
and timely reporting of disease information to CDC and state and local
health departments. Consistent with recommendations supported by our
state and local surveillance partners and described in the 1995 report,
Integrating Public Health Information and Surveillance Systems, NEDSS
includes data standards, an internet based communications
infrastructure built on industry standards, and policy-level agreements
on data access, sharing, burden reduction, and protection of
confidentiality.
To support NEDSS, CDC has developed an information system, the
NEDSS Base System (NBS), which uses NEDSS technical and information
standards. The NBS is currently deployed to 16 states, including AL,
AR, ID, MD, ME, MT, NE, NM, NV, RI, SC, TN, TX, VA, VT, and WY.
CDC is requesting a three-year OMB clearance extension of
collecting the NEDSS data. There are no costs to respondents other than
their time. The average total annualized burden for the Weekly
Morbidity Reports and the Annual Summary Report is 9,384 hours.
[[Page 64230]]
Estimated Annualized Burden Hours
----------------------------------------------------------------------------------------------------------------
Number of Average burden
Respondents Number of responses per per response
respondents respondent (in hours)
----------------------------------------------------------------------------------------------------------------
Weekly Reporting
----------------------------------------------------------------------------------------------------------------
States......................................................... 50 52 3
Territories.................................................... 5 52 1.5
Cities......................................................... 2 52 3
----------------------------------------------------------------------------------------------------------------
Annual Reporting
----------------------------------------------------------------------------------------------------------------
States......................................................... 50 1 16
Territories.................................................... 5 1 10
Cities......................................................... 2 1 16
----------------------------------------------------------------------------------------------------------------
Dated: November 8, 2007.
Maryam I. Daneshvar,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. E7-22315 Filed 11-14-07; 8:45 am]
BILLING CODE 4163-18-P
