Availability of Draft Toxicological Profiles, 60020-60021 [E7-20819]

Download as PDF 60020 Federal Register / Vol. 72, No. 204 / Tuesday, October 23, 2007 / Notices DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Toxic Substances and Disease Registry [ATSDR–236] Availability of Draft Toxicological Profiles Agency for Toxic Substances and Disease Registry (ATSDR), Department of Health and Human Services (HHS). ACTION: Notice of availability. AGENCY: SUMMARY: The Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments and Reauthorization Act of 1986 (SARA), section 104(i)(3) [42 U.S.C. 9604(i)(3)] directs the Administrator of ATSDR to prepare toxicological profiles of priority hazardous substances and to revise and publish each updated toxicological profile as necessary. This notice announces the availability of the 21st set of toxicological profiles, which consists of one new draft and six updated drafts, prepared by ATSDR for review and comment. DATES: In order to be considered, comments on these draft toxicological profiles must be received on or before February 22, 2008. Comments received after the close of the public comment period will be considered at the discretion of ATSDR on the basis of what is deemed to be in the best interest of the general public. ADDRESSES: Requests for printed copies of the draft toxicological profiles should be sent to the attention of Ms. Olga Dawkins, Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Mailstop F–32, 1600 Clifton Road, NE., Atlanta, Georgia 30333. Electronic access to these documents is also available at the ATSDR Web site: http://www.atsdr.cdc.gov/toxpro2.html. Comments regarding the draft toxicological profiles should be sent to the attention of Ms. Nickolette Roney, Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Mailstop F–32, 1600 Clifton Road, NE., Atlanta, Georgia 30333. Requests for printed copies of the draft toxicological profiles must be in writing, and must specifically identify the hazardous substance(s) profile(s) that you wish to receive. ATSDR reserves the right to provide only one copy of each profile requested, free of charge. In case of extended distribution delays, requestors will be notified. Written comments and other data submitted in response to this notice and the draft toxicological profiles should bear the docket control number ATSDR– 236. Send one copy of all comments and three copies of all supporting documents to Ms. Roney at the above stated address by the end of the comment period. Because all public comments regarding ATSDR toxicological profiles are available for public inspection, no confidential business information or other confidential information should be submitted in response to this notice. FOR FURTHER INFORMATION CONTACT: Ms. Olga Dawkins, Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Mailstop F–32, 1600 Clifton Road, NE., Atlanta, Georgia 30333, telephone 1 (888) 422–8737 or (770) 488–3315. SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization Act (SARA) (Pub. L. 99–499) amends the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA or Superfund) (42 U.S.C. 9601 et seq.) by establishing certain responsibilities for the ATSDR and the U.S. Environmental Protection Agency (EPA) with regard to hazardous substances which are most commonly found at facilities on the CERCLA National Priorities List (NPL). Among these responsibilities is that the Administrator of ATSDR prepare toxicological profiles for substances included on the priority lists of hazardous substances. These lists rfrederick on PROD1PC67 with NOTICES Document 1. 2. 3. 4. 5. 6. .............................. .............................. .............................. .............................. .............................. .............................. VerDate Aug<31>2005 identified 275 hazardous substances that ATSDR and EPA determined pose the most significant potential threat to human health. The availability of the revised priority list of 275 hazardous substances was announced in the Federal Register on December 7, 2005 (70 FR 72840). For prior versions of the list of substances see Federal Register notices dated April 17, 1987 (52 FR 12866); October 20, 1988 (53 FR 41280); October 26, 1989 (54 FR 43619); October 17, 1990 (55 FR 42067); October 17, 1991 (56 FR 52166); October 28, 1992 (57 FR 48801); February 28, 1994 (59 FR 9486); April 29, 1996 (61 FR 18744); November 17, 1997 (62 FR 61332); October 21, 1999 (64 FR 56792); October 25, 2001 (66 FR 54014) and November 7, 2003 (68 FR 63098). [CERCLA also requires ATSDR to assure the initiation of a research program to fill data needs associated with the substances.] Section 104(i)(3) of CERCLA [42 U.S.C. 9604(i)(3)] outlines the content of these profiles. Each profile will include an examination, summary and interpretation of available toxicological information and epidemiologic evaluations. This information and these data are to be used to identify the levels of significant human exposure for the substance and the associated health effects. The profiles must also include a determination of whether adequate information on the health effects of each substance is available or in the process of development. When adequate information is not available, ATSDR, in cooperation with the National Toxicology Program (NTP), is required to assure the initiation of research to determine these health effects. Although key studies for each of the substances were considered during the profile development process, this Federal Register notice seeks to solicit any additional studies, particularly unpublished data and ongoing studies, which will be evaluated for possible addition to the profiles now or in the future. The following draft toxicological profiles will be made available to the public on or about October 17, 2007. Hazardous substance CAS No. Boron (Update) .............................................................................................................................................. Chlorine* ........................................................................................................................................................ 1,4-Dioxane (Update) .................................................................................................................................... Ethylbenzene (Update) .................................................................................................................................. Ethylene glycol (Update) ............................................................................................................................... Plutonium (Update) ....................................................................................................................................... Plutonium –238 ...................................................................................................................................... Plutonium –239 ...................................................................................................................................... Plutonium –240 ...................................................................................................................................... 007440–42–8 007782–50–5 000123–91–1 000100–41–4 000107–21–1 007440–07–5 013981–16–3 015117–48–3 014119–33–6 15:33 Oct 22, 2007 Jkt 214001 PO 00000 Frm 00022 Fmt 4703 Sfmt 4703 E:\FR\FM\23OCN1.SGM 23OCN1 60021 Federal Register / Vol. 72, No. 204 / Tuesday, October 23, 2007 / Notices Document Hazardous substance CAS No. 7. .............................. Styrene (Update) ........................................................................................................................................... 000100–42–5 * Denotes new profile. Indians, Alaska Natives and Native Hawaiians, which respond to local needs and are consistent with evidencebased prevention practices. A detailed description of the funding opportunity may be found at http:// www.olderindians.org. All profiles issued as ‘‘Drafts for Public Comment’’ represent ATSDR’s best efforts to provide important toxicological information on priority hazardous substances. We are seeking public comments and additional information which may be used to supplement these profiles. ATSDR remains committed to providing a public comment period for these documents as a means to best serve public health and our clients. Dated: October 17, 2007. Ken Rose, Director, Office of Policy, Planning and Evaluation, National Center for Environmental Health/Agency for Toxic Substances and Disease Registry. [FR Doc. E7–20819 Filed 10–22–07; 8:45 am] BILLING CODE 4163–70–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration on Aging Notice of Availability Purpose of Notice: Availability of funding opportunity announcement. Funding Opportunity Title/Program Name: Older Americans Act (OAA), Title VI, Part A—Grants for Native Americans, Part B—Grants for Native Hawaiian Programs and Part C—Grants for the Native American Caregiver Support Program. Announcement Type: This is the initial announcement for this funding opportunity. Funding Opportunity Number: Program Announcement No. HHS– 2008–AoA–Title VI–0802. Statutory Authority: The Older Americans Act, Public Law 109–365. Catalog of Federal Domestic Assistance (CFDA) Number: 93.047, Title VI Parts A and B and 93.052, Title VI Part C. Dates: The deadline date for the submission of applications is January 22, 2008. rfrederick on PROD1PC67 with NOTICES I. Funding Opportunity Description This announcement seeks proposals for grants to provide nutritional and supportive services to Indian elders and Native Hawaiian elders under Part A and Part B and Family Caregiver support services under Part C. The goal of these programs is to increase home and community based services to older VerDate Aug<31>2005 15:33 Oct 22, 2007 Jkt 214001 II. Award Information 1. Funding Instrument Type: Grant. 2. Anticipated Total Priority Area Funding per Budget Period: The Administration on Aging (AoA) will accept applications for funding for a three-year project period, April 1, 2008 to March 31, 2011, in FY 2008 under the OAA, Title VI, Part A—Grants for Native Americans, Part B—Grants for Native Hawaiian Programs and Part C— Grants for the Native American Caregiver Support Program. Current annual funding levels for Title VI, Part A and Part B range from $72,850 to $135,500. Current annual funding levels for Title VI, Part C range from $14,720 to $58,230. Distribution of funds among tribal organizations and Native Hawaiian organizations is subject to the availability of appropriations to carry out Title VI. Funding is based on the number of eligible elders over the age of 60 in your proposed service area. Successful applications from new grantees will be funded pending availability of additional funds. For those applying for Title VI, Parts A and B funding you have the option to also apply for Part C. However, to apply for Part C, you must apply for both Part A and Part C or Part B and Part C. III. Eligibility Criteria and Other Requirements 1. Eligible Applicants Eligibility for grant awards is limited to all current Title VI, Part A and Part B grantees, current grantees who wish to leave a consortium, and eligible federally recognized Indian tribal organizations that are not now participating in Title VI, and would like to apply as a new grantee. Those Tribes who were a part of a consortium receiving a Title VI grant in 1991 and applying individually will be considered an ‘‘old grantee’’. Proof of being a part of a consortium that was funded in FY 1991 must be submitted as part of the application. A tribal organization or Indian tribe must meet the application requirements contained in sections 612(a), 612(b), and 612(c) of PO 00000 Frm 00023 Fmt 4703 Sfmt 4703 the OAA. A public or nonprofit organization serving Native Hawaiians must meet the application requirements contained in sections 622(1), 622(2), and 625 of the OAA. Under the Native American Caregiver Support Program, a tribal or Native Hawaiian organization must meet the requirements as contained in section 631 of the OAA. These sections are described in the application kit. 2. Cost Sharing or Matching Cost Sharing or matching does not apply to these grants. 3. DUNS Number All grant applicants must obtain a DU-N-S number from Dun and Bradstreet. It is a nine-digit identification number, which provides unique identifiers of single business entities. The D-U-N-S number is free and easy to obtain from http://www.dnb.com/US/duns_update/. 4. Intergovernmental Review Executive Order 12372, Intergovernmental Review of Federal Programs, is not applicable to these grant applications. IV. Application and Submission Information 1. Address To Request Application Package Application kits are available by writing to the U.S. Department of Health and Human Services, Administration on Aging, Office for American Indian, Alaskan Native, and Native Hawaiian Programs, Washington, DC 20201, by calling 202/357–3537, or online at http://www.olderindians.org. 2. Address for Application Submission Applications must be sent overnight delivery to the U.S. Department of Health and Human Services, Administration on Aging, Office of Grants Management, 1 Massachusetts Ave, NW., Room 4604, Washington, DC 20001, attn: Stephen Daniels (HHS– 2008–AoA–Title VI–0802). You must submit one original and two copies of the application. 3. Submission Dates and Times To receive consideration, applications must be received by the deadline listed in the DATES section of this Notice. E:\FR\FM\23OCN1.SGM 23OCN1

Agencies

[Federal Register Volume 72, Number 204 (Tuesday, October 23, 2007)]
[Notices]
[Pages 60020-60021]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E7-20819]



[[Page 60020]]

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[ATSDR-236]


Availability of Draft Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (HHS).

ACTION: Notice of availability.

-----------------------------------------------------------------------

SUMMARY: The Comprehensive Environmental Response, Compensation, and 
Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments 
and Reauthorization Act of 1986 (SARA), section 104(i)(3) [42 U.S.C. 
9604(i)(3)] directs the Administrator of ATSDR to prepare toxicological 
profiles of priority hazardous substances and to revise and publish 
each updated toxicological profile as necessary. This notice announces 
the availability of the 21st set of toxicological profiles, which 
consists of one new draft and six updated drafts, prepared by ATSDR for 
review and comment.

DATES: In order to be considered, comments on these draft toxicological 
profiles must be received on or before February 22, 2008. Comments 
received after the close of the public comment period will be 
considered at the discretion of ATSDR on the basis of what is deemed to 
be in the best interest of the general public.

ADDRESSES: Requests for printed copies of the draft toxicological 
profiles should be sent to the attention of Ms. Olga Dawkins, Division 
of Toxicology and Environmental Medicine, Agency for Toxic Substances 
and Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta, 
Georgia 30333. Electronic access to these documents is also available 
at the ATSDR Web site: http://www.atsdr.cdc.gov/toxpro2.html.
    Comments regarding the draft toxicological profiles should be sent 
to the attention of Ms. Nickolette Roney, Division of Toxicology and 
Environmental Medicine, Agency for Toxic Substances and Disease 
Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta, Georgia 
30333.
    Requests for printed copies of the draft toxicological profiles 
must be in writing, and must specifically identify the hazardous 
substance(s) profile(s) that you wish to receive. ATSDR reserves the 
right to provide only one copy of each profile requested, free of 
charge. In case of extended distribution delays, requestors will be 
notified.
    Written comments and other data submitted in response to this 
notice and the draft toxicological profiles should bear the docket 
control number ATSDR-236. Send one copy of all comments and three 
copies of all supporting documents to Ms. Roney at the above stated 
address by the end of the comment period. Because all public comments 
regarding ATSDR toxicological profiles are available for public 
inspection, no confidential business information or other confidential 
information should be submitted in response to this notice.

FOR FURTHER INFORMATION CONTACT: Ms. Olga Dawkins, Division of 
Toxicology and Environmental Medicine, Agency for Toxic Substances and 
Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta, 
Georgia 30333, telephone 1 (888) 422-8737 or (770) 488-3315.

SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization 
Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental 
Response, Compensation, and Liability Act (CERCLA or Superfund) (42 
U.S.C. 9601 et seq.) by establishing certain responsibilities for the 
ATSDR and the U.S. Environmental Protection Agency (EPA) with regard to 
hazardous substances which are most commonly found at facilities on the 
CERCLA National Priorities List (NPL). Among these responsibilities is 
that the Administrator of ATSDR prepare toxicological profiles for 
substances included on the priority lists of hazardous substances. 
These lists identified 275 hazardous substances that ATSDR and EPA 
determined pose the most significant potential threat to human health. 
The availability of the revised priority list of 275 hazardous 
substances was announced in the Federal Register on December 7, 2005 
(70 FR 72840). For prior versions of the list of substances see Federal 
Register notices dated April 17, 1987 (52 FR 12866); October 20, 1988 
(53 FR 41280); October 26, 1989 (54 FR 43619); October 17, 1990 (55 FR 
42067); October 17, 1991 (56 FR 52166); October 28, 1992 (57 FR 48801); 
February 28, 1994 (59 FR 9486); April 29, 1996 (61 FR 18744); November 
17, 1997 (62 FR 61332); October 21, 1999 (64 FR 56792); October 25, 
2001 (66 FR 54014) and November 7, 2003 (68 FR 63098). [CERCLA also 
requires ATSDR to assure the initiation of a research program to fill 
data needs associated with the substances.] Section 104(i)(3) of CERCLA 
[42 U.S.C. 9604(i)(3)] outlines the content of these profiles. Each 
profile will include an examination, summary and interpretation of 
available toxicological information and epidemiologic evaluations. This 
information and these data are to be used to identify the levels of 
significant human exposure for the substance and the associated health 
effects. The profiles must also include a determination of whether 
adequate information on the health effects of each substance is 
available or in the process of development. When adequate information 
is not available, ATSDR, in cooperation with the National Toxicology 
Program (NTP), is required to assure the initiation of research to 
determine these health effects.
    Although key studies for each of the substances were considered 
during the profile development process, this Federal Register notice 
seeks to solicit any additional studies, particularly unpublished data 
and ongoing studies, which will be evaluated for possible addition to 
the profiles now or in the future.
    The following draft toxicological profiles will be made available 
to the public on or about October 17, 2007.

------------------------------------------------------------------------
            Document               Hazardous substance        CAS No.
------------------------------------------------------------------------
1..............................  Boron (Update).........     007440-42-8
2..............................  Chlorine*..............     007782-50-5
3..............................  1,4-Dioxane (Update)...     000123-91-1
4..............................  Ethylbenzene (Update)..     000100-41-4
5..............................  Ethylene glycol             000107-21-1
                                  (Update).
6..............................  Plutonium (Update).....     007440-07-5
                                    Plutonium -238......     013981-16-3
                                    Plutonium -239......     015117-48-3
                                    Plutonium -240......     014119-33-6

[[Page 60021]]

 
7..............................  Styrene (Update).......     000100-42-5
------------------------------------------------------------------------
* Denotes new profile.

    All profiles issued as ``Drafts for Public Comment'' represent 
ATSDR's best efforts to provide important toxicological information on 
priority hazardous substances. We are seeking public comments and 
additional information which may be used to supplement these profiles. 
ATSDR remains committed to providing a public comment period for these 
documents as a means to best serve public health and our clients.

    Dated: October 17, 2007.
Ken Rose,
Director, Office of Policy, Planning and Evaluation, National Center 
for Environmental Health/Agency for Toxic Substances and Disease 
Registry.
[FR Doc. E7-20819 Filed 10-22-07; 8:45 am]
BILLING CODE 4163-70-P