National Advisory Council; Notice of Federal Advisory Committee Meeting, 54917-54918 [E7-19063]
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Federal Register / Vol. 72, No. 187 / Thursday, September 27, 2007 / Notices
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
1061, Rockville, MD 20852. Submit
electronic comments to either https://
www.fda.gov/dockets/ecomments or
https://www.regulations.gov.
FOR FURTHER INFORMATION CONTACT:
Brenda R. Friend, Center for Biologics
Evaluation and Research (HFM–17),
Food and Drug Administration, 1401
Rockville Pike, suite 200N, Rockville,
MD 20852–1448, 301–827–6210.
SUPPLEMENTARY INFORMATION:
Food and Drug Administration
I. Background
[Docket No. 2005D–0155]
FDA is announcing the availability of
a document entitled ‘‘Guidance for
Industry: Toxicity Grading Scale for
Healthy Adult and Adolescent
Volunteers Enrolled in Preventive
Vaccine Clinical Trials,’’ dated
September 2007. The guidance provides
sponsors of vaccine trials with toxicity
grading scale tables as a guideline when
selecting the criteria to assess the
severity of clinical and laboratory
abnormalities in healthy adult and
adolescent volunteers enrolled in
clinical trials of a preventive vaccine.
FDA recommends the incorporation of
such appropriate, uniform criteria into
the investigational plan, case report
forms, and study reports and
correspondence with FDA, sponsors,
monitors, investigators, and
institutional review boards. The
parameters in the tables are not
necessarily applicable to every clinical
trial of healthy volunteers. The
parameters monitored should be
appropriate for the specific study
vaccine. In addition, the use of toxicity
grading scales to categorize adverse
events observed during clinical trials
does not replace regulatory
requirements to monitor, investigate,
and report adverse events.
In the Federal Register of May 2, 2005
(70 FR 22664), FDA announced the
availability of the draft guidance of the
same title dated April 2005. FDA
received several comments on the draft
guidance and those comments were
considered as the guidance was
finalized. A summary of changes
includes: (1) Clarification of the clinical
toxicity parameters and (2) revision of
laboratory parameter limit values based
on additional published data. The
guidance announced in this notice
finalizes the draft guidance dated April
2005.
The guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The guidance represents FDA’s current
thinking on this topic. It does not create
or confer any rights for or on any person
and does not operate to bind FDA or the
public. An alternative approach may be
U.S.C. app.2) and 21 CFR part 14
relating to advisory committees.
Dated: September 13, 2007.
Randall W. Lutter,
Deputy Commissioner for Policy.
[FR Doc. E7–19130 Filed 9–26–07; 8:45 am]
BILLING CODE 4160–01–S
Guidance for Industry: Toxicity
Grading Scale for Healthy Adult and
Adolescent Volunteers Enrolled in
Preventive Vaccine Clinical Trials;
Availability
AGENCY:
Food and Drug Administration,
HHS.
rwilkins on PROD1PC63 with NOTICES
ACTION:
Notice.
SUMMARY: The Food and Drug
Administration (FDA) is announcing the
availability of a document entitled
‘‘Guidance for Industry: Toxicity
Grading Scale for Healthy Adult and
Adolescent Volunteers Enrolled in
Preventive Vaccine Clinical Trials,’’
dated September 2007. The guidance
document provides sponsors of vaccine
trials with recommendations on
assessing the severity of clinical and
laboratory abnormalities in healthy
adult and adolescent volunteers
enrolled in clinical trials. In particular,
the guidance includes toxicity grading
scale tables to use as a guideline for
selecting the assessment criteria. The
guidance announced in this notice
finalizes the draft guidance of the same
title dated April 2005.
DATES: Submit written or electronic
comments on agency guidances at any
time.
ADDRESSES: Submit written requests for
single copies of the guidance to the
Office of Communication, Training, and
Manufacturers Assistance (HFM–40),
Center for Biologics Evaluation and
Research (CBER), Food and Drug
Administration, 1401 Rockville Pike,
suite 200N, Rockville, MD 20852–1448.
Send one self-addressed adhesive label
to assist the office in processing your
requests. The guidance may also be
obtained by mail by calling CBER at 1–
800–835–4709 or 301–827–1800. See
the SUPPLEMENTARY INFORMATION section
for electronic access to the guidance
document.
Submit written comments on the
guidance to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, rm.
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16:40 Sep 26, 2007
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54917
used if such approach satisfies the
requirements of the applicable statutes
and regulations.
II. Comments
Interested persons may, at any time,
submit to the Division of Dockets
Management (see ADDRESSES) written or
electronic comments regarding the
guidance. Submit a single copy of
electronic comments or two paper
copies of any mailed comments, except
that individuals may submit one paper
copy. Comments are to be identified
with the docket number found in the
brackets in the heading of this
document. A copy of the guidance and
received comments are available for
public examination in the Division of
Dockets Management between 9 a.m.
and 4 p.m., Monday through Friday.
III. Electronic Access
Persons with access to the Internet
may obtain the guidance at either https://
www.fda.gov/cber/guidelines.htm or
https://www.fda.gov/ohrms/dockets/
default.htm.
Dated: September 20, 2007.
Jeffrey Shuren,
Assistant Commissioner for Policy.
[FR Doc. E7–19155 Filed 9–26–07; 8:45 am]
BILLING CODE 4160–01–S
DEPARTMENT OF HOMELAND
SECURITY
Federal Emergency Management
Agency
[Docket No. FEMA–2007–0008]
National Advisory Council; Notice of
Federal Advisory Committee Meeting
Federal Emergency
Management Agency, DHS.
ACTION: Notice of Federal Advisory
Committee Meeting.
AGENCY:
SUMMARY: This notice announces the
date, time, location and agenda for the
inaugural meeting of the National
Advisory Council (NAC). At the
meeting, members will be introduced
and sworn in and the Chair and Vice
Chair will be introduced. Members will
also receive briefings on the status of the
reorganized Federal Emergency
Management Agency (FEMA) and its
programs, and to discuss the vision,
priorities and structure for the NAC.
The meeting will be open to the public.
DATES: Meeting Dates: Monday, October
22, 2007, 9:45 a.m. to 5 p.m. and
Tuesday, October 23, 2007, 9 a.m. to
4:30 p.m. A public comment period will
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54918
Federal Register / Vol. 72, No. 187 / Thursday, September 27, 2007 / Notices
take place on October 23, 2007 between
3:15 p.m. and 4:30 p.m.
Comment Date: Written comments or
requests to make oral presentations
must be received by October 15, 2007.
ADDRESSES: The meeting will be held in
Ballroom B/C of the Sheraton Crystal
City Hotel, 1800 Jefferson Davis
Highway, Arlington, Virginia 22202.
Persons wishing to make an oral
presentation or who are unable to attend
or speak at the meeting may submit
written comments. Written comments
and requests to make oral presentations
at the meeting should reach Alyson
Price at the address listed below and
must be received by October 15, 2007.
All submissions received must include
the docket number FEMA–2007–0008
and may be submitted by any one of the
following methods:
Federal Rulemaking Portal: https://
www.regulations.gov. Follow
instructions for submitting comments
on the Web site.
E-mail: FEMA-RULES@dhs.gov.
Include docket number in the subject
line of the message.
Facsimile: (866) 466–5370.
Mail: Alyson Price, Designated
Federal Officer, Federal Emergency
Management Agency, 500 C Street, SW.,
(E Street, 3rd Floor), Washington, DC
20472.
Hand Delivery/Courier: National
Advisory Council, DFO c/o Rules
Docket Clerk, Office of the Chief
Counsel, Federal Emergency
Management Agency, Room 835, 500 C
Street, SW., Washington, DC 20472.
Instructions: All submissions received
must include the docket number:
FEMA–2007–0008. Comments received
will also be posted without alteration at
https://www.regulations.gov, including
any personal information provided. You
may want to read the Privacy Act Notice
located on the Privacy and Use Notice
link on the Administration Navigation
Bar of the Web site https://
www.regulations.gov.
Docket: For access to the docket to
read background documents or
comments received by the National
Advisory Council, go to https://
www.regulations.gov.
rwilkins on PROD1PC63 with NOTICES
FOR FURTHER INFORMATION CONTACT:
Alyson Price, Designated Federal
Officer, Federal Emergency Management
Agency, 500 C Street, SW., (E Street, 3rd
Floor), Washington, DC 20472,
telephone 202–646–3746, fax 202–646–
3061, and e-mail Alyson.Price@dhs.gov.
SUPPLEMENTARY INFORMATION: Notice of
this meeting is given under the Federal
Advisory Committee Act (FACA), Public
Law 92–463, as amended (5 U.S.C. App.
1 et seq.). The NAC will be holding its
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first meeting on Monday and Tuesday,
October 22 and 23, 2007, in Ballroom B/
C of the Sheraton Crystal City Hotel,
1800 Jefferson Davis Highway,
Arlington, Virginia 22202.
Agenda of Council Meeting, October
22–23, 2007
The tentative agenda includes the
following:
Monday, October 22, 2007
(1) Introduction of the Chair and Vice
Chair;
(2) Introduction and swearing-in of
members;
(3) FEMA Administrator’s vision for
the NAC;
(4) Introduction of FEMA leadership;
(5) FEMA programs overview; and
(6) Review of FEMA Strategic Plan.
Tuesday, October 23, 2007
(1) Summary of previous day;
(2) Structure and assignment of
Subcommittee Chairs;
(3) Discussion Wrap-up/Next Steps;
(4) Public comment period; and
(5) Travel instructions/paperwork.
A public comment period will take
place on October 23, 2007, between 3:15
p.m. and 4:30 p.m.
Public Attendance: The meeting is
open to the public. Persons with
disabilities who require special
assistance should advise Alyson Price of
their anticipated special needs as early
as possible. Members of the public who
wish to make comments on Tuesday,
October 23 between 3:15 p.m. and 4:30
p.m. are requested to register in
advance. In order to allow as many
people as possible to speak, speakers are
requested to limit their remarks to three
minutes. For those wishing to submit
written comments, please follow the
procedure noted above.
Dated: September 20, 2007.
R. David Paulison,
Administrator, Federal Emergency
Management Agency.
[FR Doc. E7–19063 Filed 9–26–07; 8:45 am]
BILLING CODE 9110–21–P
INTER-AMERICAN FOUNDATION
BOARD MEETING
Sunshine Act Meetings
October 1, 2007. 9 a.m.–
1 p.m.
PLACE: 901 N. Stuart Street, Tenth Floor,
Arlington, Virginia 22203.
STATUS: Open to the public except for
the portion specified as closed session
as provided in 22 CFR part 1004.4(b)
and (f).
TIME AND DATE:
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MATTERS TO BE CONSIDERED:
• Approval of the Minutes of the
January 22, 2007, Meeting of the Board
of Directors.
• President’s Report.
• Program Update.
• Operations Update.
• External Affairs.
• Congressional Affairs.
• Advisory Council.
PORTIONS TO BE OPEN TO THE PUBLIC:
• Approval of the Minutes of the
January 22, 2007, Meeting of the Board
of Directors.
• President’s Report.
• Program Update.
• Operations Update.
• External Affairs.
• Congressional Affairs.
• Advisory Council.
PORTIONS TO BE CLOSED TO THE PUBLIC:
• Closed session as provided in 22
CFR part 1004.4(b) and (f).
Dated: September 19, 2007.
Jennifer R. Hodges,
General Counsel, (703) 306–4320.
[FR Doc. 07–4804 Filed 9–25–07; 3:15 pm]
BILLING CODE 7025–01–M
DEPARTMENT OF THE INTERIOR
Fish and Wildlife Service
Information Collection Sent to the
Office of Management and Budget
(OMB) for Approval; OMB Control
Number 1018–0094; Federal Fish and
Wildlife Permit Applications and
Reports—Native Endangered and
Threatened Species
Fish and Wildlife Service,
Interior.
ACTION: Notice; request for comments.
AGENCY:
SUMMARY: We (Fish and Wildlife
Service) have sent an Information
Collection Request (ICR) to OMB for
review and approval. The ICR, which is
summarized below, describes the nature
of the collection and the estimated
burden and cost. This ICR is scheduled
to expire on September 30, 2007. We
may not conduct or sponsor and a
person is not required to respond to a
collection of information unless it
displays a currently valid OMB control
number. However, under OMB
regulations, we may continue to
conduct or sponsor this information
collection while it is pending at OMB.
DATES: You must submit comments on
or before October 29, 2007.
ADDRESSES: Send your comments and
suggestions on this ICR to the Desk
Officer for the Department of the
Interior at OMB-OIRA at (202) 395–6566
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Agencies
[Federal Register Volume 72, Number 187 (Thursday, September 27, 2007)]
[Notices]
[Pages 54917-54918]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E7-19063]
=======================================================================
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DEPARTMENT OF HOMELAND SECURITY
Federal Emergency Management Agency
[Docket No. FEMA-2007-0008]
National Advisory Council; Notice of Federal Advisory Committee
Meeting
AGENCY: Federal Emergency Management Agency, DHS.
ACTION: Notice of Federal Advisory Committee Meeting.
-----------------------------------------------------------------------
SUMMARY: This notice announces the date, time, location and agenda for
the inaugural meeting of the National Advisory Council (NAC). At the
meeting, members will be introduced and sworn in and the Chair and Vice
Chair will be introduced. Members will also receive briefings on the
status of the reorganized Federal Emergency Management Agency (FEMA)
and its programs, and to discuss the vision, priorities and structure
for the NAC. The meeting will be open to the public.
DATES: Meeting Dates: Monday, October 22, 2007, 9:45 a.m. to 5 p.m. and
Tuesday, October 23, 2007, 9 a.m. to 4:30 p.m. A public comment period
will
[[Page 54918]]
take place on October 23, 2007 between 3:15 p.m. and 4:30 p.m.
Comment Date: Written comments or requests to make oral
presentations must be received by October 15, 2007.
ADDRESSES: The meeting will be held in Ballroom B/C of the Sheraton
Crystal City Hotel, 1800 Jefferson Davis Highway, Arlington, Virginia
22202. Persons wishing to make an oral presentation or who are unable
to attend or speak at the meeting may submit written comments. Written
comments and requests to make oral presentations at the meeting should
reach Alyson Price at the address listed below and must be received by
October 15, 2007. All submissions received must include the docket
number FEMA-2007-0008 and may be submitted by any one of the following
methods:
Federal Rulemaking Portal: https://www.regulations.gov. Follow
instructions for submitting comments on the Web site.
E-mail: FEMA-RULES@dhs.gov. Include docket number in the subject
line of the message.
Facsimile: (866) 466-5370.
Mail: Alyson Price, Designated Federal Officer, Federal Emergency
Management Agency, 500 C Street, SW., (E Street, 3rd Floor),
Washington, DC 20472.
Hand Delivery/Courier: National Advisory Council, DFO c/o Rules
Docket Clerk, Office of the Chief Counsel, Federal Emergency Management
Agency, Room 835, 500 C Street, SW., Washington, DC 20472.
Instructions: All submissions received must include the docket
number: FEMA-2007-0008. Comments received will also be posted without
alteration at https://www.regulations.gov, including any personal
information provided. You may want to read the Privacy Act Notice
located on the Privacy and Use Notice link on the Administration
Navigation Bar of the Web site https://www.regulations.gov.
Docket: For access to the docket to read background documents or
comments received by the National Advisory Council, go to https://
www.regulations.gov.
FOR FURTHER INFORMATION CONTACT: Alyson Price, Designated Federal
Officer, Federal Emergency Management Agency, 500 C Street, SW., (E
Street, 3rd Floor), Washington, DC 20472, telephone 202-646-3746, fax
202-646-3061, and e-mail Alyson.Price@dhs.gov.
SUPPLEMENTARY INFORMATION: Notice of this meeting is given under the
Federal Advisory Committee Act (FACA), Public Law 92-463, as amended (5
U.S.C. App. 1 et seq.). The NAC will be holding its first meeting on
Monday and Tuesday, October 22 and 23, 2007, in Ballroom B/C of the
Sheraton Crystal City Hotel, 1800 Jefferson Davis Highway, Arlington,
Virginia 22202.
Agenda of Council Meeting, October 22-23, 2007
The tentative agenda includes the following:
Monday, October 22, 2007
(1) Introduction of the Chair and Vice Chair;
(2) Introduction and swearing-in of members;
(3) FEMA Administrator's vision for the NAC;
(4) Introduction of FEMA leadership;
(5) FEMA programs overview; and
(6) Review of FEMA Strategic Plan.
Tuesday, October 23, 2007
(1) Summary of previous day;
(2) Structure and assignment of Subcommittee Chairs;
(3) Discussion Wrap-up/Next Steps;
(4) Public comment period; and
(5) Travel instructions/paperwork.
A public comment period will take place on October 23, 2007,
between 3:15 p.m. and 4:30 p.m.
Public Attendance: The meeting is open to the public. Persons with
disabilities who require special assistance should advise Alyson Price
of their anticipated special needs as early as possible. Members of the
public who wish to make comments on Tuesday, October 23 between 3:15
p.m. and 4:30 p.m. are requested to register in advance. In order to
allow as many people as possible to speak, speakers are requested to
limit their remarks to three minutes. For those wishing to submit
written comments, please follow the procedure noted above.
Dated: September 20, 2007.
R. David Paulison,
Administrator, Federal Emergency Management Agency.
[FR Doc. E7-19063 Filed 9-26-07; 8:45 am]
BILLING CODE 9110-21-P