Research Plan for Dosimetric and Toxicologic Assessment of Amphibole Asbestos Fiber-Containing Materials From Libby, MI, 53569 [E7-18521]

Download as PDF Federal Register / Vol. 72, No. 181 / Wednesday, September 19, 2007 / Notices maintaining and operating the EPA CBI computer facilities located in Research Triangle Park, NC. Access to TSCA data, including CBI, was to continue until September 30, 2007. The contract has been extended until September 30, 2008. CSC and its subcontractors, Digital Intelligence Systems Corporation (Disys) of 4151 LaFayette Center Drive, Suite 600, Chantilly, VA; Tek Systems of 7437 Race Road S, Hanover, MD; Yoh I.T. of 1818 Market Street, Philadelphia, PA; Excel Management Systems of 691 N. High Street, 2nd Floor, Columbus, OH; Kenrob, Inc. of 44084 Riverside Parkway, Suite 125, Leesburg, VA; Paloma Systems of 7002 Evergreen Court, Annandale, VA; APPTIS of 4800 Westfields Blvd. Chantilly, VA 20151, previously PlanetGov of 14155 Newbrook Drive, Chantilly, VA; Superlative Technologies, Inc. (STI) of 8300 Greensboro Drive, Suite 425, McLean, VA; SoftPath of 1945 Cliff Valley Way NE, Suite 312, Atlanta, GA; and Apex Systems of 4400 Cox Road, Suite 200, Glen Allen, VA will continue to undertake the identified function. It is possible that the contract will be extended a further year, until September 30, 2009. If this occurs no further notice will be provided. EPA is issuing this notice to inform all submitters of information under all sections of TSCA that EPA may provide CSC and its identified subcontractors access to materials, including CBI materials on a need-to-know basis until September 30, 2008, unless the contract is extended again. All access to TSCA CBI under this contract will take place at EPA Headquarters and Research Triangle Park, NC facilities, the CSC facility at Research Triangle Park, NC, and also remote electronic access using secure means. CSC and subcontractor personnel are required to sign nondisclosure agreements and will be briefed on appropriate security procedures before they are permitted access to TSCA CBI. List of Subjects rwilkins on PROD1PC63 with NOTICES Dated: September 13, 2007. Brion T. Cook, Director, Information Management Division, Office of Pollution Prevention and Toxics. [FR Doc. E7–18491 Filed 9–18–07; 8:45 am] VerDate Aug<31>2005 16:58 Sep 18, 2007 Jkt 211001 [FRL–8470–6] Research Plan for Dosimetric and Toxicologic Assessment of Amphibole Asbestos Fiber-Containing Materials From Libby, MI Environmental Protection Agency (EPA). ACTION: Notice of Data Availability. AGENCY: SUMMARY: This action announces a plan for a series of research projects aimed at addressing the toxicological effects and dosimetry of amphibole asbestoscontaminated vermiculite from Libby, Montana (referred to here as Libby amphibole). Although available human data establish the toxicity of asbestos, and preliminary dose response analyses for Libby amphibole have been developed, these estimates can be refined by addressing some of the key uncertainties that exist due to gaps in our understanding or lack of quantitative descriptions of internal dosimetry and toxicological effects. This planned set of projects is aimed at addressing these gaps and providing tools for quantitative characterization, including a comparative analysis of the toxicity of Libby amphibole relative to asbestos fibers and asbestos-like mineral occurrences. Other key areas of research will also inform the risk assessment, including inherent toxicity of Libby amphibole relative to other forms of asbestos and differential susceptibility, including that of different life stages. EPA conducted an internal and external review of the research plan and has documented the responses to comments. FOR FURTHER INFORMATION CONTACT: Stephen H. Gavett, PhD, Pulmonary Toxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development (B143–01), Environmental Protection Agency, Research Triangle Park, NC 27711; telephone number: 919–541–2555; fax number: 919–541– 0026; e-mail address: gavett.stephen@epa.gov. SUPPLEMENTARY INFORMATION: I. General Information Environmental protection, Confidential business information. BILLING CODE 6560–50–S ENVIRONMENTAL PROTECTION AGENCY A. How Can I Get Copies of the Research Plan and the Responses to Peer Review Comments? 1. Electronic Access. You may access this Federal Register document electronically through the EPA Internet under the Federal Register listings at https://www.epa.gov/fedrgstr/ or https:// www.epa.gov/region8/superfund/libby. PO 00000 Frm 00048 Fmt 4703 Sfmt 4703 53569 Dated: September 13, 2007. James Woolford, Director, Office of Superfund Remediation and Technology Innovation. [FR Doc. E7–18521 Filed 9–18–07; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY [EPA–HQ–OPP–2007–0934; FRL–8149–7] FIFRA Scientific Advisory Panel; Notice of Public Meeting Environmental Protection Agency (EPA). ACTION: Notice. AGENCY: SUMMARY: There will be a 4–day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review the interpretation of the Ecological Significance of Atrazine Stream-Water Concentrations Using a StatisticallyDesigned Monitoring Program. DATES: The meeting will be held on December 4-7, 2007, from approximately 8:30 a.m. to 5 p.m, Eastern Standard Time. Comments. The Agency encourages written comments be submitted by November 19, 2007 and requests for oral comments be submitted by November 27, 2007. Written comments and requests to make oral comments are accepted until the date of the meeting but anyone submitting written comments after November 19, 2007 should contact the Designated Federal Official (DFO) listed under FOR FURTHER INFORMATION CONTACT. For additional instructions, see Unit I.C. of the SUPPLEMENTARY INFORMATION. Nominations. Nominations of candidates to serve as ad hoc members of the FIFRA SAP for this meeting should be provided on or before October 3, 2007. Special accommodations. For information on access or services for individuals with disabilities, and to request accommodation of a disability, please contact the DFO listed under FOR FURTHER INFORMATION CONTACT at least 10 days prior to the meeting to give EPA as much time as possible to process your request. ADDRESSES: The meeting will be held at the Crowne Plaza – Washington National Airport, 1489 Jefferson Davis Highway, Arlington, VA 22202. The telephone number for the Crowne Plaza – Washington National Airport is (703) 416–1600. Comments. Submit your comments, identified by docket identification (ID) E:\FR\FM\19SEN1.SGM 19SEN1

Agencies

[Federal Register Volume 72, Number 181 (Wednesday, September 19, 2007)]
[Notices]
[Page 53569]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E7-18521]


-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

[FRL-8470-6]


Research Plan for Dosimetric and Toxicologic Assessment of 
Amphibole Asbestos Fiber-Containing Materials From Libby, MI

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of Data Availability.

-----------------------------------------------------------------------

SUMMARY: This action announces a plan for a series of research projects 
aimed at addressing the toxicological effects and dosimetry of 
amphibole asbestos-contaminated vermiculite from Libby, Montana 
(referred to here as Libby amphibole). Although available human data 
establish the toxicity of asbestos, and preliminary dose response 
analyses for Libby amphibole have been developed, these estimates can 
be refined by addressing some of the key uncertainties that exist due 
to gaps in our understanding or lack of quantitative descriptions of 
internal dosimetry and toxicological effects. This planned set of 
projects is aimed at addressing these gaps and providing tools for 
quantitative characterization, including a comparative analysis of the 
toxicity of Libby amphibole relative to asbestos fibers and asbestos-
like mineral occurrences. Other key areas of research will also inform 
the risk assessment, including inherent toxicity of Libby amphibole 
relative to other forms of asbestos and differential susceptibility, 
including that of different life stages. EPA conducted an internal and 
external review of the research plan and has documented the responses 
to comments.

FOR FURTHER INFORMATION CONTACT: Stephen H. Gavett, PhD, Pulmonary 
Toxicology Branch, Experimental Toxicology Division, National Health 
and Environmental Effects Research Laboratory, Office of Research and 
Development (B143-01), Environmental Protection Agency, Research 
Triangle Park, NC 27711; telephone number: 919-541-2555; fax number: 
919-541-0026; e-mail address: gavett.stephen@epa.gov.

SUPPLEMENTARY INFORMATION: 

I. General Information

A. How Can I Get Copies of the Research Plan and the Responses to Peer 
Review Comments?

    1. Electronic Access. You may access this Federal Register document 
electronically through the EPA Internet under the Federal Register 
listings at https://www.epa.gov/fedrgstr/ or https://www.epa.gov/region8/
superfund/libby.

    Dated: September 13, 2007.
James Woolford,
Director, Office of Superfund Remediation and Technology Innovation.
 [FR Doc. E7-18521 Filed 9-18-07; 8:45 am]
BILLING CODE 6560-50-P
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.