National Institutes of Nursing Research; Notice of Meeting, 52892-52893 [07-4568]
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Federal Register / Vol. 72, No. 179 / Monday, September 17, 2007 / Notices
MyoD, which is an inhibitor of the
CDK4. CDK4 is one of a number of
cyclin-dependent kinases which control
progression through the cell cycle
through their ability to phosphorylate
particular substrates at the correct phase
of the cell cycle. CDK4 has been shown
to be involved in cell cycle control
through its ability to regulate the
activity of the retinoblastoma protein,
pRb, an activator of genes essential for
cell division.
Inhibitors of the cyclin-dependent
kinases, such as the peptides described
in this invention, prevent cell cycle
progression and induce cells to exit the
cell cycle into the Go state. The peptides
described in this invention prevent the
phosphorylation of pRb by CDK4, an
obligate step for entry into the cell
cycle. Osteosarcomas and
habdosarcomas are two types of tumors
known to over-express pRb. The
inhibitor described in this invention
may be useful in treating these cancers
or other diseases which have been
specifically linked to over-expression of
active pRb.
Laboratory of Biochemistry and
Molecular Biology is seeking statements
of capability or interest from parties
interested in collaborative research to
further develop, evaluate, or
commercialize the described cdk4
inhibitory peptides or equivalent
peptide mimetics. Please contact John
D. Hewes, PhD at 301–435–3121 or
hewesj@mail.nih.gov for more
information.
Applications
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of a meeting of the
Board of Scientific Counselors, National
Institute of Neurological Disorders and
Stroke.
The meeting will be closed to the
public as indicated below in accordance
with the provisions set forth in section
552b(c)(6), Title 5 U.S.C., as amended
for the review, discussion, and
evaluation of individual intramural
programs and projects conducted by the
National Institute of Neurological
Disorders And Stroke, including
consideration of personnel
qualifications and performance, and the
competence of individual investigators,
the disclosure of which would
constitute a clearly unwarranted
invasion of personal privacy.
Method to treat proliferative
disorders, including cancer.
Anti-proliferative therapeutics.
Research tool to study the cell cycle.
Advantages: Expression of this
peptide either as a fusion protein with
GST or GFP results in the cessation of
cell growth.
jlentini on PROD1PC65 with NOTICES
Market
An estimated 1,444,920 new cancer
diagnoses in the U.S. in 2007.
600,000 deaths caused by cancer in
the U.S. in 2006.
Cancer is the second leading cause of
death in the United States.
It is estimated that market for cancer
drugs would double to $50 billion a year
in 2010 from $25 billion in 2006.
Development Status: The technology
is currently in the pre-clinical stage of
development.
Inventors: Bruce M. Paterson and Jianmin Zhang (NCI).
Publication: JM Zhang, et al. Coupling
of the cell cycle and myogenesis
through the cyclin D1-dependent
interaction of MyoD with cdk4. EMBO
J. 1999 Feb 15;18(4):926–933.
Patent Status: U.S. Patent Application
No. 10/018,964 filed 11 Apr 2002,
claiming priority to 18 Jun 1999 (HHS
Reference No. E–153–1998/0–US–03).
Licensing Status: Available for
exclusive or non-exclusive licensing.
Licensing Contact: Jennifer Wong;
301/435–4633; wongje@mail.nih.gov.
Collaborative Research Opportunity:
The National Cancer Institute’s
VerDate Aug<31>2005
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Dated: September 6, 2007.
Steven M. Ferguson,
Director, Division of Technology Development
and Transfer, Office of Technology Transfer,
National Institutes of Health.
[FR Doc. E7–18192 Filed 9–14–07; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Boulevard, Conference Room A, Rockville,
MD 20852.
Time: October 2, 2007, 8:30 a.m. to 12 p.m.
Agenda: To review and evaluate personal
qualifications and performance, and
competence of individual investigators.
Place: Hyatt Regency Bethesda, One
Bethesda Metro Center, 7400 Wisconsin
Avenue, Susquehanna/Severn Room,
Bethesda, MD 20814.
Contact Person: Alan P. Koretsky, PhD,
Scientific Director, Division of Intramural
Research. National Institute Of Neurological
Disorders & Stroke, NIH, 35 Convent Drive,
Room 6A 908, Bethesda, MD 20892, 301–
435–2232, koretskya@ninds.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.853, Clinical Research
Related to Neurological Disorders; 93.854,
Biological Basis Research in the
Neurosciences, National Institutes of Health,
HHS).
National Institutes of Health
National Institute of Neurological
Disorders And Stroke; Notice of
Closed Meeting
Dated: September 6, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–4566 Filed 9–14–07; 8:45 am]
BILLING CODE 4140–01–M
Name of Committee: Board of Scientific
Counselors, National Institute of
Neurological Disorders and Stroke.
Date: September 30–October 2, 2007.
Time: September 30, 2007, 7 p.m. to 10
p.m.
Agenda: To review and evaluate personal
qualifications and performance, and
competence of individual investigators.
Place: Hyatt Regency Bethesda, One
Bethesda Metro Center, 7400 Wisconsin
Avenue, Susquehanna/Severn Room,
Bethesda, MD 20814.
Time: October 1, 2007, 8:30 a.m. to 6:30
p.m.
Agenda: To review and evaluate personal
qualifications and performance, and
competence of individual investigators.
Place: National Institutes of Health,
Neuroscience Center, 6001 Executive
PO 00000
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institutes of Nursing
Research; Notice of Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of a meeting of the
National Advisory Council for Nursing
Research.
The meeting will be open to the
public as indicated below, with
attendance limited to space available.
Individuals who play to attend and need
special assistance, such as sign language
interpretation or other reasonable
accommodations, should notify the
Contact Person listed below in advance
of the meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Advisory
Council for Nursing Research.
Date: September 25–26, 2007.
Open: September 25, 2007, 1 p.m. to 5 p.m.
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Federal Register / Vol. 72, No. 179 / Monday, September 17, 2007 / Notices
jlentini on PROD1PC65 with NOTICES
Agenda: Discussion of program policies
and Issues.
Place: National Institutes of Health,
Building 31, 31 Center Drive, 6C, Room 10,
Bethesda, MD 20892.
Open: September 26, 2007, 9 a.m. to 9:15
a.m.
Agenda: Discussion of program policies
and Issues.
Place: National Institutes of Health,
Building 31, 31 Center Drive, 6C, Room 10,
Bethesda, MD 20892.
Closed: September 26, 2007, 9:15 a.m. to
Adjournment.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Building 31, 31 Center Drive, 6C, Room 10,
Bethesda, MD 20892.
Contact Person: Mary E. Kerr, FAAN, RN,
PhD, Deputy Director, National Institute of
Nursing, National Institutes of Health, 31
Center Drive, Room 5B–05, Bethesda, MD
20892–2178, 301/496–8230,
kerrme@mail.nih.gov.
This notice is being published less than 15
days prior to the meeting due to the timing
limitations imposed by the review and
funding cycle.
Any member of the public interested in
presenting oral comments to the committee
may notify the Contact Person listed on this
notice at least 10 days in advance of the
meeting. Interested individuals and
representatives of organizations may submit
a letter of intent, a brief description of the
organization represented, and a short
description of the oral presentation. Only one
representative of an organization may be
allowed to present oral comments and if
accepted by the committee, presentations
may be limited to five minutes. Both printed
and electronic copies are requested for the
record. In addition, any interested person
may file written comments with the
committee by forwarding their statement to
the Contact Person listed on this notice. The
statement should include the name, address,
telephone number and when applicable, the
business or professional affiliation of the
interested person.
In the interest of security, NIH has
instituted stringent procedures for entrance
on to the NIH campus. All visitor vehicles,
including taxicabs, hotel, and airport shuttles
will be inspected before being allowed on
campus. Visitors will be asked to show one
form of identification (for example, a
government-issued photo ID, driver’s license,
or passport) and to state the purpose of their
visit.
Information is also available on the
Institute’s/Center’s home page: https://
www.nih.gov/ninr/a_advisory.html, where an
agenda and any additional information for
the meeting will be posted when available.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.361, Nursing Research,
National Institutes of Health, HHS).
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institutes of Health
National Institute on Alcohol Abuse
and Alcoholism; Notice of Closed
Meeting
National Institute on Alcohol Abuse
and Alcoholism; Notice of Closed
Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of the following
meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute on
Alcohol Abuse and Alcoholism Special
Emphasis Panel, Institutional Training Grants
(T32s).
Date: October 18, 2007.
Time: 8:30 a.m. to 2 p.m.
Agenda: To review and evaluate grant
applications.
Place: Doubletree Hotel, Executive Meeting
Center—Bethesda, 8120 Wisconsin Avenue,
Bethesda, MD 20814.
Contact Person: Lorraine Gunzerath, PhD,
MBA. Scientific Review Administrator,
National Institute on Alcohol Abuse And
Alcoholism, Office of Extramural Activities,
Extramural Project Review Branch, 5635
Fishers Lane, Room 3043, Bethesda, MD
20892–9304, 301–433–2369,
Igunzera@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.271, Alcohol Research
Career Development Awards for Scientists
and Clinicians; 93.272, Alcohol National
Research Service Awards for Research
Training; 93.273, Alcohol Research Programs;
93.891, Alcohol Research Center Grants,
National Institutes of Health, HHS).
Dated: September 7, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–4569 Filed 9–14–07; 8:45 am]
Jkt 211001
Name of Committee: National Institute on
Alcohol Abuse and Alcoholism Initial
Review Group, Health Services and
Behavioral Research Review Subcommittee.
Date: October 24–25, 2007.
Time: 8:30 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: Doubletree Hotel, Executive Meeting
Center—Bethesda, 8120 Wisconsin Avenue,
Bethesda, MD 20814.
Contact Person: Lorraine Gunzerath, PhD,
MBA, Scientific Review Administrator,
National Institute on Alcohol Abuse and
Alcoholism, Office of Extramural Activities,
Extramural Project Review Branch, 5635
Fishers lane, Room 3043, Bethesda, MD
20892–9304, 301–443–2369,
Igunzera@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.271, Alcohol Research
Career Development Awards for Scientists
and Clinicians; 93.272, Alcohol National
Research Awards for Research Training;
93.273, Alcohol Research Programs; 93.891,
Alcohol Research Center Grants, National
Institutes of Health, HHS).
Dated: September 7, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–4570 Filed 9–14–07; 8:45 am]
BILLING CODE 4140–01–M
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Mental Health;
Notice of Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
BILLING CODE 4140–01–M
17:00 Sep 14, 2007
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of the following
meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
BILLING CODE 4140–01–M
Dated: September 6, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–4568 Filed 9–14–07; 8:45 am]
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]]>Agencies
[Federal Register Volume 72, Number 179 (Monday, September 17, 2007)]
[Notices]
[Pages 52892-52893]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 07-4568]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institutes of Nursing Research; Notice of Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice is hereby given of a meeting of
the National Advisory Council for Nursing Research.
The meeting will be open to the public as indicated below, with
attendance limited to space available. Individuals who play to attend
and need special assistance, such as sign language interpretation or
other reasonable accommodations, should notify the Contact Person
listed below in advance of the meeting.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications, the disclosure of which would
constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: National Advisory Council for Nursing
Research.
Date: September 25-26, 2007.
Open: September 25, 2007, 1 p.m. to 5 p.m.
[[Page 52893]]
Agenda: Discussion of program policies and Issues.
Place: National Institutes of Health, Building 31, 31 Center
Drive, 6C, Room 10, Bethesda, MD 20892.
Open: September 26, 2007, 9 a.m. to 9:15 a.m.
Agenda: Discussion of program policies and Issues.
Place: National Institutes of Health, Building 31, 31 Center
Drive, 6C, Room 10, Bethesda, MD 20892.
Closed: September 26, 2007, 9:15 a.m. to Adjournment.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, Building 31, 31 Center
Drive, 6C, Room 10, Bethesda, MD 20892.
Contact Person: Mary E. Kerr, FAAN, RN, PhD, Deputy Director,
National Institute of Nursing, National Institutes of Health, 31
Center Drive, Room 5B-05, Bethesda, MD 20892-2178, 301/496-8230,
kerrme@mail.nih.gov.
This notice is being published less than 15 days prior to the
meeting due to the timing limitations imposed by the review and
funding cycle.
Any member of the public interested in presenting oral comments
to the committee may notify the Contact Person listed on this notice
at least 10 days in advance of the meeting. Interested individuals
and representatives of organizations may submit a letter of intent,
a brief description of the organization represented, and a short
description of the oral presentation. Only one representative of an
organization may be allowed to present oral comments and if accepted
by the committee, presentations may be limited to five minutes. Both
printed and electronic copies are requested for the record. In
addition, any interested person may file written comments with the
committee by forwarding their statement to the Contact Person listed
on this notice. The statement should include the name, address,
telephone number and when applicable, the business or professional
affiliation of the interested person.
In the interest of security, NIH has instituted stringent
procedures for entrance on to the NIH campus. All visitor vehicles,
including taxicabs, hotel, and airport shuttles will be inspected
before being allowed on campus. Visitors will be asked to show one
form of identification (for example, a government-issued photo ID,
driver's license, or passport) and to state the purpose of their
visit.
Information is also available on the Institute's/Center's home
page: https://www.nih.gov/ninr/a_advisory.html, where an agenda and
any additional information for the meeting will be posted when
available.
(Catalogue of Federal Domestic Assistance Program Nos. 93.361,
Nursing Research, National Institutes of Health, HHS).
Dated: September 6, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 07-4568 Filed 9-14-07; 8:45 am]
BILLING CODE 4140-01-M
