National Institute for Child Health and Human Development; National Children's Study 2007 Research Plan, 41339-41340 [E7-14514]

Download as PDF Federal Register / Vol. 72, No. 144 / Friday, July 27, 2007 / Notices DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Biomedical Imaging and Bioengineering; Notice of Meeting jlentini on PROD1PC65 with NOTICES Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of a meeting of the National Advisory Council for Biomedical Imaging and Bioengineering. The meeting will be open to the public as indicated below, with attendance limited to space available. Individuals who plan to attend and need special assistance, such as sign language interpretation or other reasonable accommodations, should notify the Contact Person listed below in advance of the meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Advisory Council for Biomedical Imaging and Bioengineering. Date: September 17, 2007. Open: 8:30 a.m. to 1:15 p.m. Agenda: Report from the Institute Director, other Institute staff and presentations of working group reports. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Closed: 1:15 p.m. to 4 p.m. Agenda:To review and evaluate grant applications. Place: Bethesda Marriott Suites, 6711 Democracy Boulevard, Bethesda, MD 20817. Contact Person: Anthony Demsey, PhD, Director, National Institute of Biomedical Imaging and Bioengineering, 6701 Democracy Blvd., Room 241, Bethesda, MD 20892. Any interested person may file written comments with the committee by forwarding the statement to the Contact Person listed on this notice. The statement should include the name, address, telephone number and when applicable, the business or professional affiliation of the interested person. Information is also available on the Institute’s/Center’s home page: https:// www.nibib1.nih.gov/about/NACBIB/ NACBIB.htm, where an agenda and any additional information for the meeting will be posted when available. VerDate Aug<31>2005 16:53 Jul 26, 2007 Jkt 211001 Dated: July 19, 2007. Jennifer Spaeth, Director, Office of Federal Advisory COmmittee Policy. [FR Doc. 07–3669 Filed 7–26–07; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Neurological Disorders and Stroke Special Emphasis Panel, Migraine: Neural Mechanisms and Risk Factors for Progression. Date: August 1, 2007. Time: 11 a.m. to 3 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852, (Telephone Conference Call). Contact Person: Richard D. Crosland, PhD, Scientific Review Administrator, Scientific Review Branch, Division of Extramural Research, NINDS/NIH/DHHS/Neuroscience Center, 6001 Executive Blvd., Suite 3208, MSC 9529, Bethesda, MD 20892–9529, 301– 594–0635, rc218u@nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.853, Clinical Research Related to Neurological Disorders; 93.854, Biological Basis Research in the Neurosciences, National Institutes of Health, HHS) Dated: July 19, 2007. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. 07–3670 Filed 7–26–07; 8:45 am] BILLING CODE 4140–01–M PO 00000 Frm 00055 Fmt 4703 Sfmt 4703 41339 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Biochemical Risk Markers. Date: July 31, 2007. Time: 1 p.m. to 2 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, 2C212, Bethesda, MD 20892, (Telephone Conference Call). Contact Person: William Cruce, PhD, Health Scientist Administrator, Scientific Review Office. National Institute on Aging, National Institutes of Health, Room 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20814, 301–401–7704, crucew@nia.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.866, Aging Research, National Institutes of Health, HHS) Dated: July 19, 2007. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. 07–3671 Filed 7–26–07; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute for Child Health and Human Development; National Children’s Study 2007 Research Plan Notice; opportunity for review and comment. ACTION: SUMMARY: Attached is the proposed Research Plan for the National E:\FR\FM\27JYN1.SGM 27JYN1 jlentini on PROD1PC65 with NOTICES 41340 Federal Register / Vol. 72, No. 144 / Friday, July 27, 2007 / Notices Children’s Study (NCS). The purpose of this notice is to inform scientific reviewers, professional colleagues, contributors, and all who are interested in this ground-breaking initiative, of the opportunity for review and comment. The Research Plan describes the Study’s background, design, measures, and the rationale for their selections in sufficient detail so that readers can understand the basis of the Study and how it will be carried out. This plan was developed with input from scientists and other professionals across the country and from multiple federal agencies, especially the National Institute of Child Health and Human Development (NICHD) and the National Institute of Environmental Health Sciences (NIEHS) at the National Institutes of Health (NIH), the Centers for Disease Control and Prevention, and the U.S. Environmental Protection Agency (EPA). We welcome constructive comments and proposals for how the National Children’s Study might address the pressing health concerns of our nation’s children even more effectively. Procedures for commenting and communicating about the Research Plan are found on the NCS Web site at: https:// www.nationalchildrensstudy.gov/ research/research_plan/index.cfm. DATES: Submit responses to the National Children’s Study (see below) on or before September 25, 2007. FOR FURTHER INFORMATION CONTACT: The National Children’s Study, NICHD, NIH, 6100 Executive Blvd., Room 5C01, Bethesda, MD 20892. Telephone: 301– 594–9147, Fax: 301–480–1222, e-mail: ncsinfo@mail.nih.gov, Internet at: https://www.nationalchildrensstudy.gov. SUPPLEMENTARY INFORMATION: The National Children’s Study is a long-term study of child health conducted in the United States. By following 100,000 children from before birth to age 21, Study researchers hope to better understand how children’s genes and their environments interact to affect their health and development. In the Study, ‘‘environment’’ includes factors such as: Air, water, and house dust; what children eat; how they are cared for; the safety of their neighborhoods; and how often they see a doctor. The goal of the National Children’s Study is to provide information that will ultimately lead to improvements in the health, development, and well-being of children. The primary aim of the Study is to investigate the separate and combined effects of environmental exposures (chemical, biological, physical, psychosocial) as well as geneenvironment interactions on pregnancy VerDate Aug<31>2005 16:53 Jul 26, 2007 Jkt 211001 outcomes, child health and development, and precursors of adult disease. The Study will examine important health issues, including: birth defects and pregnancy-related problems, injuries, asthma, obesity and diabetes, and behavior, learning, and mental health disorders. By establishing links between children’s environments and their health, and charting their development through infancy, childhood, and early adulthood, the Study hopes to determine the root causes of many childhood and adult diseases. Findings from the Study will benefit all Americans by providing researchers, health care providers, and public health officials with information from which to develop prevention strategies, health and safety guidelines, and possibly new treatments and cures for disease. The Study will employ a national probability sampling approach to select locations for conduct of the study. The sampling design utilizes a multistage clustered approach. In the first stage, 105 locations (generally corresponding to single counties) were randomly selected from all U.S. counties. Seven of the locations will serve as the Vanguard Locations and will participate in the pilot phase of the Study. Because the focus of the study includes assessment of the impact of exposures that occur early in pregnancy, both pregnant women and their partners, and women of childbearing age, comprise the initial target population for enrollment in each of the Study Locations. At the time of enrollment, participants will be asked to provide written informed consent for participation in the study. Three distinct groups will be enrolled and followed: Pregnant women and their partners, couples planning pregnancy, and women not currently planning pregnancy but with some probability of becoming pregnant during the four year enrollment timeframe. The National Children’s Study is in a unique position to answer many questions regarding the effects of environmental exposures on the longterm health of children. The focus on exposures prior to and early in pregnancy is a unique feature of this study, as is the breadth of planned exposure and outcome measurements. As technology continues to evolve, stored data specimens (biologic and environmental) will provide a valuable resource to answer important questions for future generations. The prospective longitudinal design of the study will permit an in-depth examination of the effects of environmental exposures as they unfold PO 00000 Frm 00056 Fmt 4703 Sfmt 4703 over the course of development. This will include an unprecedented, processoriented understanding of how exposures at particular points in development lead to both immediate and long-term consequences for children, and what circumstances, characteristics, or genetic predispositions mediate or moderate the relation between exposure and outcome. The size and representative nature of the sample will permit both valid inferences about the U.S. population as a whole, and exploration of subgroupspecific patterns of adaptation and maladapation. Additionally, the data collected for the Study will provide a platform for future research. Data, biological samples, and environmental samples will be available for future studies as science evolves and new questions arise. The Study will serve as an exceptional resource both for science and for society. Duane Alexander, Director, National Institutes of Child Health and Human Development, National Institutes of Health. [FR Doc. E7–14514 Filed 7–26–07; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Agency Information Collection Activities; Transportation Entry and Manifest of Goods Subject to CBP Inspection and Permit U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Proposed collection; comments requested. AGENCY: SUMMARY: U.S. Customs and Border Protection (CBP) of the Department of Homeland Security has submitted the following information collection request to the Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act: Transportation Entry and Manifest of Goods Subject to CBP Inspection and Permit. This is a proposed extension of an information collection that was previously approved. CBP is proposing that this information collection be extended with a change to the burden hours. This document is published to obtain comments from the public and affected agencies. This proposed information collection was previously published in the Federal Register (72 FR 15893) on E:\FR\FM\27JYN1.SGM 27JYN1

Agencies

[Federal Register Volume 72, Number 144 (Friday, July 27, 2007)]
[Notices]
[Pages 41339-41340]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E7-14514]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Institute for Child Health and Human Development; 
National Children's Study 2007 Research Plan

ACTION: Notice; opportunity for review and comment.

-----------------------------------------------------------------------

SUMMARY: Attached is the proposed Research Plan for the National

[[Page 41340]]

Children's Study (NCS). The purpose of this notice is to inform 
scientific reviewers, professional colleagues, contributors, and all 
who are interested in this ground-breaking initiative, of the 
opportunity for review and comment. The Research Plan describes the 
Study's background, design, measures, and the rationale for their 
selections in sufficient detail so that readers can understand the 
basis of the Study and how it will be carried out. This plan was 
developed with input from scientists and other professionals across the 
country and from multiple federal agencies, especially the National 
Institute of Child Health and Human Development (NICHD) and the 
National Institute of Environmental Health Sciences (NIEHS) at the 
National Institutes of Health (NIH), the Centers for Disease Control 
and Prevention, and the U.S. Environmental Protection Agency (EPA). We 
welcome constructive comments and proposals for how the National 
Children's Study might address the pressing health concerns of our 
nation's children even more effectively. Procedures for commenting and 
communicating about the Research Plan are found on the NCS Web site at: 
https://www.nationalchildrensstudy.gov/research/research_plan/
index.cfm.

DATES: Submit responses to the National Children's Study (see below) on 
or before September 25, 2007.

FOR FURTHER INFORMATION CONTACT: The National Children's Study, NICHD, 
NIH, 6100 Executive Blvd., Room 5C01, Bethesda, MD 20892. Telephone: 
301-594-9147, Fax: 301-480-1222, e-mail: ncsinfo@mail.nih.gov, Internet 
at: https://www.nationalchildrensstudy.gov.

SUPPLEMENTARY INFORMATION: The National Children's Study is a long-term 
study of child health conducted in the United States. By following 
100,000 children from before birth to age 21, Study researchers hope to 
better understand how children's genes and their environments interact 
to affect their health and development. In the Study, ``environment'' 
includes factors such as: Air, water, and house dust; what children 
eat; how they are cared for; the safety of their neighborhoods; and how 
often they see a doctor.
    The goal of the National Children's Study is to provide information 
that will ultimately lead to improvements in the health, development, 
and well-being of children. The primary aim of the Study is to 
investigate the separate and combined effects of environmental 
exposures (chemical, biological, physical, psychosocial) as well as 
gene-environment interactions on pregnancy outcomes, child health and 
development, and precursors of adult disease.
    The Study will examine important health issues, including: birth 
defects and pregnancy-related problems, injuries, asthma, obesity and 
diabetes, and behavior, learning, and mental health disorders. By 
establishing links between children's environments and their health, 
and charting their development through infancy, childhood, and early 
adulthood, the Study hopes to determine the root causes of many 
childhood and adult diseases. Findings from the Study will benefit all 
Americans by providing researchers, health care providers, and public 
health officials with information from which to develop prevention 
strategies, health and safety guidelines, and possibly new treatments 
and cures for disease.
    The Study will employ a national probability sampling approach to 
select locations for conduct of the study. The sampling design utilizes 
a multistage clustered approach. In the first stage, 105 locations 
(generally corresponding to single counties) were randomly selected 
from all U.S. counties. Seven of the locations will serve as the 
Vanguard Locations and will participate in the pilot phase of the 
Study. Because the focus of the study includes assessment of the impact 
of exposures that occur early in pregnancy, both pregnant women and 
their partners, and women of childbearing age, comprise the initial 
target population for enrollment in each of the Study Locations. At the 
time of enrollment, participants will be asked to provide written 
informed consent for participation in the study. Three distinct groups 
will be enrolled and followed: Pregnant women and their partners, 
couples planning pregnancy, and women not currently planning pregnancy 
but with some probability of becoming pregnant during the four year 
enrollment timeframe.
    The National Children's Study is in a unique position to answer 
many questions regarding the effects of environmental exposures on the 
long-term health of children. The focus on exposures prior to and early 
in pregnancy is a unique feature of this study, as is the breadth of 
planned exposure and outcome measurements. As technology continues to 
evolve, stored data specimens (biologic and environmental) will provide 
a valuable resource to answer important questions for future 
generations.
    The prospective longitudinal design of the study will permit an in-
depth examination of the effects of environmental exposures as they 
unfold over the course of development. This will include an 
unprecedented, process-oriented understanding of how exposures at 
particular points in development lead to both immediate and long-term 
consequences for children, and what circumstances, characteristics, or 
genetic predispositions mediate or moderate the relation between 
exposure and outcome. The size and representative nature of the sample 
will permit both valid inferences about the U.S. population as a whole, 
and exploration of subgroup-specific patterns of adaptation and 
maladapation.
    Additionally, the data collected for the Study will provide a 
platform for future research. Data, biological samples, and 
environmental samples will be available for future studies as science 
evolves and new questions arise. The Study will serve as an exceptional 
resource both for science and for society.

Duane Alexander,
Director, National Institutes of Child Health and Human Development, 
National Institutes of Health.
 [FR Doc. E7-14514 Filed 7-26-07; 8:45 am]
BILLING CODE 4140-01-P

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