National Center on Minority Health and Health Disparities; Notice of Meeting, 30018-30019 [07-2662]
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30018
Federal Register / Vol. 72, No. 103 / Wednesday, May 30, 2007 / Notices
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Development Status: The technology
is currently in the pre-clinical stage of
development.
Inventors: Robert C. Moschel (NCI) et
al.
Relevant Publication: A manuscript
directly related to the above technology
will be available as soon as it is
accepted for publication.
Patent Status: U.S. Patent Application
No. 11/683,310 filed 07 Mar 2007 (HHS
Reference No. E–307–2004/1–US–01).
Licensing Status: Available for
exclusive and non-exclusive licensing.
Licensing Contact: Adaku
Nwachukwu, J.D.; 301/435–5560;
madua@mail.nih.gov.
Inhibition of ABC Transporters by
Transmembrane Domain Analogs
Description of Technology: ABC
transporters contain multiple
transmembrane domains and are
involved in the translocation of a variety
of substrates across cell membranes.
Upregulation of these transporters
contributes to multiple drug resistance
in cancer chemotherapy wherein these
transporters export chemotherapeutic
agents out of cancer cells. The inventors
have found that P-glycoprotein and
ABCG2 transporter can be effectively
inhibited by properly modified peptides
corresponding to certain transmembrane
domains. This inhibition can be used to
overcome drug resistance in resistant
tumors.
Applications: Therapeutics that
enhance cancer treatments.
Market: Cancer is the second leading
cause of death in the United States;
600,000 deaths caused by cancer in
2006; Worldwide incidence of new
cancer patients is forecast to increase
from 4.2 million cases in the major
cancer markets in 2005 to 4.6 million in
2010; Global anticancer market was
worth over $42 billion in 2005 and by
2010, the global cancer market is
expected to generate sales in excess of
$60 billion.
Development Status: The technology
is currently in the pre-clinical stage of
development.
Inventors: Nadya I. Tarasova et al.
(NCI)
Publications:
1. NI Tarasova et al. Transmembrane
inhibitors of P-glycoprotein, an ABC
transporter. J Med Chem. 2005 Jun
2;48(11):3768–3775.
2. NI Tarasova et al. Inhibition of Gprotein-coupled receptor function by
disruption of transmembrane domain
interactions. J Biol Chem. 1999 Dec
3;274(49):34911–34915.
Patent Status: U.S. Patent Application
No. 10/130,192 filed 13 May 2002 (HHS
Reference No. E–019–2000/2–US–02);
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PCT Patent Application No. PCT/
US2000/31817 filed 17 Nov 2000 (HHS
Reference No. E–019–2000/2–PCT–01);
U.S. Provisional Patent Application No.
60/166,767 filed 22 Nov 1999 (HHS
Reference No. E–019–2000/1–US–01);
U.S. Provisional Patent Application No.
60/166,382 filed 18 Nov 1999 (HHS
Reference No. E–019–2000/0–US–01).
Licensing Status: Available for
exclusive or non-exclusive licensing.
Licensing Contact: Jennifer Wong;
301/435–4633; wongje@mail.nih.gov.
Collaborative Research Opportunity:
The National Cancer Institute’s
Structural Biophysics Laboratory is
seeking statements of capability or
interest from parties interested in
collaborative research to further
develop, evaluate, or commercialize
inhibitors of multiple drug resistance
proteins. Please contact John D. Hewes,
Ph.D. at 301–435–3121 or
hewesj@mail.nih.gov for more
information.
Dated: May 21, 2007.
Steven M. Ferguson,
Director, Division of Technology Development
and Transfer, Office of Technology Transfer,
National Institutes of Health.
[FR Doc. E7–10332 Filed 5–29–07; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Contact Person: Lynn M. Amende, PhD,
Scientific Review Administrator, Resources
and Training Review Branch, Division of
Extramural Activities, National Cancer
Institute, 6116 Executive Blvd., Room 8105,
Bethesda, MD 20892, 301–451–4759,
amendel@mail.nih.gov.
Name of Committee: National Cancer
Institute Special Emphasis Panel; CA 07–505,
‘‘The American College of Radiology Imaging
Network (ACRIN) (Limited Competition
U01).’’
Date: June 20–21, 2007.
Time: 5 p.m. to 6 p.m.
Agenda: To review and evaluate grant
applications.
Place: Park Hyatt Philadelphia, Broad and
Walnut Streets, Philadelphia, PA 19102.
Contact Person: Kenneth L. Bielat, PhD,
Scientific Review Administrator, Resources
and Training Review Branch, Division of
Extramural Activities, National Cancer
Institute, 6116 Executive Blvd., Room 7147,
Bethesda, MD 20852, 301–496–7576,
bielatk@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.392, Cancer Construction;
93.393, Cancer Cause and Prevention
Research; 93.394, Cancer Detection and
Diagnosis Research; 93.395, Cancer
Treatment Research; 93.396, Cancer Biology
Research; 93.397, Cancer Centers Support;
93.398, Cancer Research Manpower; 93.399,
Cancer Control, National Institutes of Health,
HHS)
Dated: May 22, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–2664 Filed 5–29–07; 8:45 am]
BILLING CODE 4140–01–M
National Cancer Institute; Notice of
Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of the following
meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Cancer
Institute Initial Review Group; Subcommittee
F—Manpower & Training; NCI–F.
Date: June 13–14, 2007.
Time: 8 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: Holiday Inn Georgetown, 2101
Wisconsin Avenue, NW., Washington, DC
20007.
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Center on Minority Health and
Health Disparities; Notice of Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of a meeting of the
National Advisory Council on Minority
Health and Health Disparities.
The meeting will be open to the
public as indicated below, with
attendance limited to space available.
Individuals who plan to attend and
need special assistance, such as sign
language interpretation or other
reasonable accommodations, should
notify the Contact Person listed below
in advance of the meeting.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
E:\FR\FM\30MYN1.SGM
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Federal Register / Vol. 72, No. 103 / Wednesday, May 30, 2007 / Notices
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Advisory
Council on Minority Health and Health
Disparities.
Date: June 26, 2007.
Closed: 8:30 a.m. to 10 a.m.
Agenda: To review and evaluate grant
applications.
Place: Bethesda Marriott Suites, 6711
Democracy Boulevard, Bethesda, MD 20817.
Open: 10 a.m. to 5 p.m.
Agenda: The agenda will include Opening
Remarks, Administrative Matters, Director’s
Report, NCMHD, Concept Clearance Report,
Health Disparities Research Update,
Scientific Program Presentations, and other
business of the Council.
Place: Bethesda Marriott Suites, 6711
Democracy Boulevard, Bethesda, MD 20817.
Contact Person: Donna Brooks, Asst.
Director for Administration, National Center
on Minority Health and Health Disparities,
National Institutes of Health, 6707
Democracy Blvd., Suite 800, Bethesda, MD
20892, 301–435–2135,
brooksd@ncmhd.nih.gov.
Any member of the public interested in
presenting oral comments to the committee
may notify the Contact Person listed on this
notice at least 10 days in advance of the
meeting. interested individuals and
representatives of organizations may submit
a letter of intent, a brief description of the
organization represented, and a short
description of the oral presentation. Only one
representative of an organization may be
allowed to present oral comments and if
accepted by the committee, presentations
may be limited to five minutes. Both printed
and electronic copies are requested for the
record. In addition, any interested person
may file written comments with the
committee by forwarding their statement to
the Contact Person listed on this notice. The
statement should include the name, address,
telephone number and when applicable, the
business or professional affiliation of the
interested person.
Dated: May 23, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–2662 Filed 5–29–07; 8:45 am]
BILLING CODE 4140–01–M
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
sroberts on PROD1PC70 with NOTICES
National Institutes of Health
National Eye Institute; Notice of Closed
Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
VerDate Aug<31>2005
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is hereby given of the following
meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Eye Institute
Special Emphasis Panel; NEI Research Grant
Review Panel.
Date: June 29, 2007.
Time: 8:30 a.m. to 5 p.m.
Agenda: To review and evaluate grant
applications.
Place: Embassy Suites Hotel at the Chevy
Chase Pavilion, 4300 Military Road, NW.,
Washington, DC 20015.
Contact Person: Houmam H. Araj, PhD,
Scientific Review Administrator, Division of
Extramural Research, National Eye Institute,
NIH, 5635 Fishers Lane, Suite 1300,
Bethesda, MD 20892–9602, 301–451–2020,
haraj@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.867, Vision Research,
National Institutes of Health, HHS)
Dated: May 23, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–2661 Filed 5–29–07; 8:45 am]
BILLING CODE 4140–01–M
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Human Genome Research
Institute; Amended Notice of Meeting
Notice is hereby given of a change in
the meeting of the Genome Research
Review Committee, June 8, 2007, 1 p.m.
to June 8, 2007, 3 p.m., National
Institutes of Health, 5635 Fishers Lane,
Bethesda, MD 20892, which was
published in the Federal Register on
May 17, 2007, 72 FR 95, page 27822.
The GNOM–G telephone conference
date is changed from June 8, 2007, to
June 14, 2007. The meeting time
remains 1 p.m. to 3 p.m. The meeting
is closed to the public.
Dated: May 23, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–2663 Filed 5–29–07; 8:45 am]
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30019
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Human Genome Research
Institute; Notice of Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of the following
meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Human
Genome Research Institute Special Emphasis
Panel; Conflict SEP.
Date: June 14, 2007.
Time: 12 p.m. to 1 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 5635
Fishers Lane, Suite 4076, Bethesda, MD
20892, (Telephone Conference Call).
Contact Person: Ken D. Nakamura, PhD,
Scientific Review Administrator, Scientific
Review Branch, National Human Genome
Research Institute, National Institutes of
Health, 5635 Fishers Lane, Suite 4076, MSC
9306, Rockville, MD 20852, 301–402–0838,
nakamurk@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.172, Human Genome
Research, National Institutes of Health, HHS)
Dated: May 22, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory
Committee Policy.
[FR Doc. 07–2666 Filed 5–29–07; 8:45 am]
BILLING CODE 4140–01–M
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of General Medical
Sciences; Notice of Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice
is hereby given of the following
meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
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Agencies
[Federal Register Volume 72, Number 103 (Wednesday, May 30, 2007)]
[Notices]
[Pages 30018-30019]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 07-2662]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Center on Minority Health and Health Disparities; Notice
of Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. Appendix 2), notice is hereby given of a meeting of
the National Advisory Council on Minority Health and Health
Disparities.
The meeting will be open to the public as indicated below, with
attendance limited to space available. Individuals who plan to attend
and need special assistance, such as sign language interpretation or
other reasonable accommodations, should notify the Contact Person
listed below in advance of the meeting.
The meetings will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose
[[Page 30019]]
confidential trade secrets or commercial property such as patentable
material, and personal information concerning individuals associated
with the grant applications, the disclosure of which would constitute a
clearly unwarranted invasion of personal privacy.
Name of Committee: National Advisory Council on Minority Health
and Health Disparities.
Date: June 26, 2007.
Closed: 8:30 a.m. to 10 a.m.
Agenda: To review and evaluate grant applications.
Place: Bethesda Marriott Suites, 6711 Democracy Boulevard,
Bethesda, MD 20817.
Open: 10 a.m. to 5 p.m.
Agenda: The agenda will include Opening Remarks, Administrative
Matters, Director's Report, NCMHD, Concept Clearance Report, Health
Disparities Research Update, Scientific Program Presentations, and
other business of the Council.
Place: Bethesda Marriott Suites, 6711 Democracy Boulevard,
Bethesda, MD 20817.
Contact Person: Donna Brooks, Asst. Director for Administration,
National Center on Minority Health and Health Disparities, National
Institutes of Health, 6707 Democracy Blvd., Suite 800, Bethesda, MD
20892, 301-435-2135, brooksd@ncmhd.nih.gov.
Any member of the public interested in presenting oral comments
to the committee may notify the Contact Person listed on this notice
at least 10 days in advance of the meeting. interested individuals
and representatives of organizations may submit a letter of intent,
a brief description of the organization represented, and a short
description of the oral presentation. Only one representative of an
organization may be allowed to present oral comments and if accepted
by the committee, presentations may be limited to five minutes. Both
printed and electronic copies are requested for the record. In
addition, any interested person may file written comments with the
committee by forwarding their statement to the Contact Person listed
on this notice. The statement should include the name, address,
telephone number and when applicable, the business or professional
affiliation of the interested person.
Dated: May 23, 2007.
Jennifer Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 07-2662 Filed 5-29-07; 8:45 am]
BILLING CODE 4140-01-M