Draft Toxicological Reviews of Polybrominated Diphenyl Ethers (PBDEs): In support of the Summary Information in the Integrated Risk Information System (IRIS), 77015-77017 [E6-21969]
Download as PDF
Federal Register / Vol. 71, No. 246 / Friday, December 22, 2006 / Notices
(303) 312–6286; e-mail address:
perreault.peg@epa.gov.
SUPPLEMENTARY INFORMATION:
I. General Information
jlentini on PROD1PC65 with NOTICES
A. Does this Action Apply to Me?
This action is directed to the public
in general. This action may, however, be
of interest to those involved in
agriculture and anyone involved with
the distribution and application of
pesticides for agricultural purposes.
Others involved with pesticides in a
non-agricultural setting may also be
affected. In addition, it may be of
interest to others, such as, those persons
who are or may be required to conduct
testing of chemical substances under the
Federal Food, Drug, and Cosmetic Act
(FFDCA), or the Federal Insecticide,
Fungicide, and Rodenticide Act
(FIFRA). Since other entities may also
be interested, the Agency has not
attempted to describe all the specific
entities that may be affected by this
action. If you have any questions
regarding the applicability of this action
to a particular entity, consult the person
listed under FOR FURTHER INFORMATION
CONTACT.
B. What Should I Consider as I Prepare
My Comments for EPA?
1. Submitting CBI. Do not submit this
information to EPA through
regulations.gov or e-mail. Clearly mark
the part or all of the information that
you claim to be CBI. For CBI
information in a disk or CD ROM that
you mail to EPA, mark the outside of the
disk or CD ROM as CBI and then
identify electronically within the disk or
CD ROM the specific information that is
claimed as CBI. In addition to one
complete version of the comment that
includes information claimed as CBI, a
copy of the comment that does not
contain the information claimed as CBI
must be submitted for inclusion in the
public docket. Information so marked
will not be disclosed except in
accordance with procedures set forth in
40 CFR part 2.
2. Tips for preparing your comments.
When submitting comments, remember
to:
i. Identify the document by docket ID
number and other identifying
information (subject heading, Federal
Register date and page number).
ii. Follow directions. The Agency may
ask you to respond to specific questions
or organize comments by referencing a
Code of Federal Regulations (CFR) part
or section number.
iii. Explain why you agree or disagree;
suggest alternatives and substitute
language for your requested changes.
VerDate Aug<31>2005
17:45 Dec 21, 2006
Jkt 211001
iv. Describe any assumptions and
provide any technical information and/
or data that you used.
v. If you estimate potential costs or
burdens, explain how you arrived at
your estimate in sufficient detail to
allow for it to be reproduced.
vi. Provide specific examples to
illustrate your concerns and suggest
alternatives.
vii. Explain your views as clearly as
possible, avoiding the use of profanity
or personal threats.
viii. Make sure to submit your
comments by the comment period
deadline identified. In addition to the
sources listed in this unit, you may
obtain copies of the amended Colorado
Certification Plan, other related
documents, or additional information by
contacting:
1. Peg Perreault at the address listed
under FOR FURTHER INFORMATION
CONTACT.
2. John Scott, Colorado Department of
Agriculture, 700 Kipling St., Suite 4000,
Lakewood, CO 80215; telephone
number: (303) 239–4178; e-mail address:
John.Scott@ag.state.co.us.
3. Richard Pont, Field and External
Affairs Division (7506C), Office of
Pesticide Programs, Environmental
Protection Agency, 1200 Pennsylvania
Ave., NW., Washington, DC 20460–
0001; telephone number: (703) 305–
6448; e-mail address:
pont.richard@epa.gov.
II. What Action is the Agency Taking?
EPA has reviewed the revised
Colorado Certification Plan and has
determined that it complies with FIFRA
and its implementing regulations at 40
CFR part 171. Accordingly, the Agency
is announcing its intent to approve the
amended State Plan on a contingency
basis pending promulgation of revised
Colorado Rules and Regulations
Pertaining to the Administration and
Enforcement of the Colorado Pesticide
Applicators’ Act on January 1, 2007, and
is seeking public comment.
List of Subjects
Environmental protection, Education,
Pests and pesticides.
Dated: December 5, 2006.
Robert E. Roberts,
Regional Administrator, Region VIII.
[FR Doc. E6–21973 Filed 12–21–06; 8:45 am]
BILLING CODE 6560–50–S
PO 00000
Frm 00056
Fmt 4703
Sfmt 4703
77015
ENVIRONMENTAL PROTECTION
AGENCY
[FRL–8260–3; Docket ID No. EPA–HQ–ORD–
2006–0838]
Draft Toxicological Reviews of
Polybrominated Diphenyl Ethers
(PBDEs): In support of the Summary
Information in the Integrated Risk
Information System (IRIS)
Environmental Protection
Agency (EPA).
ACTION: Notice of External Peer-Review
Panel Meeting and Public Comment
Period.
AGENCY:
SUMMARY: EPA is announcing that the
Oak Ridge Institute of Science and
Education (ORISE), under an
Interagency agreement between the
Department of Energy and EPA, will
convene an independent panel of
experts and organize and conduct an
external peer-review workshop to
review the external review draft
documents titled, ‘‘Toxicological
Review of TetraBDE (BDE–47): In
Support of Summary Information in the
Integrated Risk Information System
(IRIS)’’ (NCEA–S–2537); ‘‘Toxicological
Review of PentaBDE (BDE–99): In
Support of Summary Information in the
Integrated Risk Information System
(IRIS)’’ (NCEA–S–2538); ‘‘Toxicological
Review of HexaBDE (BDE–153): In
Support of Summary Information in the
Integrated Risk Information System
(IRIS)’’ (NCEA–S–2539); and
‘‘Toxicological Review of DecaBDE
(BDE–209): In Support of Summary
Information in the Integrated Risk
Information System (IRIS)’’ (NCEA–S–
2540). The EPA also is announcing a
public comment period for the external
review draft documents.
The public comment period and the
external peer-review workshop are
separate processes that provide
opportunities for all interested parties to
comment on the document. In addition
to consideration by EPA, all public
comments submitted in accordance with
this notice will also be forwarded to
ORISE for consideration by the external
peer-review panel prior to the
workshop.
EPA is releasing these draft
documents solely for the purpose of predissemination peer review under
applicable information quality
guidelines. These documents have not
been formally disseminated by EPA.
They do not represent and should not be
construed to represent any Agency
policy or determination. ORISE invites
the public to register to attend this
workshop as observers. In addition,
ORISE invites the public to give brief
E:\FR\FM\22DEN1.SGM
22DEN1
77016
Federal Register / Vol. 71, No. 246 / Friday, December 22, 2006 / Notices
oral comments at the workshop
regarding the draft documents under
review. The draft documents and EPA’s
peer-review charge are available via the
Internet on NCEA’s home page under
the Recent Additions and the
Publications menus at https://
www.epa.gov/ncea. When finalizing the
draft documents, EPA will consider
ORISE’s report of the comments and
recommendations from the external
peer-review workshop and any public
comments that EPA receives in
accordance with this notice.
The external peer-review panel
workshop will begin on February 22,
2007, at 9 a.m. and end at 4 p.m. The
public comment period begins
December 22, 2006 and ends February 5,
2007. Technical comments should be in
writing and must be received by EPA by
February 5, 2007. Comments from the
public received by this date will be
submitted to the external peer-review
panel prior to the workshop.
DATES:
The external peer-review
workshop will be held at The American
Geophysical Union, 2000 Florida
Avenue NW., Washington, DC, 20009–
1277. ORISE is organizing, convening,
and conducting the peer-review
workshop. To attend the workshop,
register by February 8, 2007, via the
Internet at https://www.orau.gov/pbde.
You may also register by calling ORISE
at 865–576–2922, sending a facsimile to
865–241–3168, or sending an e-mail to
Margaret Lyday at lydaym@orau.gov.
You must register by February 8, 2007,
if you wish to provide brief oral
comments at the workshop.
The draft documents, Toxicological
Review of TetraBDE (BDE–47): In
Support of Summary Information in the
Integrated Risk Information System
(IRIS); PentaBDE (BDE–99): In Support
of Summary Information in the
Integrated Risk Information System
(IRIS); HexaBDE (BDE–153): In Support
of Summary Information in the
Integrated Risk Information System
(IRIS); and DecaBDE (BDE–209): In
Support of Summary Information in the
Integrated Risk Information System
(IRIS), are available via the Internet on
the National Center for Environmental
Assessment’s (NCEA) home page under
the Recent Additions and the
Publications menus at https://
www.epa.gov/ncea. A limited number of
paper copies are available from NCEA’s
Technical Information Staff. Please
contact the Technical Information Staff
by telephone at 202–564–3261 or by
facsimile at 202–565–0050. If you are
requesting a paper copy, please provide
your name, mailing address, and the
jlentini on PROD1PC65 with NOTICES
ADDRESSES:
VerDate Aug<31>2005
17:45 Dec 21, 2006
Jkt 211001
document title. Copies are not available
from ORISE.
Comments may be submitted
electronically via www.regulations.gov,
by mail, by facsimile, or by hand
delivery/courier. Please follow the
detailed instructions as provided in the
SUPPLEMENTARY INFORMATION section of
this notice.
FOR FURTHER INFORMATION CONTACT: For
information on the peer review
workshop, contact Margaret Lyday,
ORISE, by mail at P.O. Box 117, MS 17,
Oak Ridge, TN 37831–0117; by phone at
865–576–2922; by facsimile at 865–241–
3168; or by e-mail at lydaym@orau.gov.
For information on the public
comment period, contact the Office of
Environmental Information Docket; by
phone at 202–566–1752; by facsimile at
202–566–1753; or by e-mail at
ORD.Docket@epa.gov.
If you have questions about the
document, contact Samantha J. Jones,
IRIS Staff, National Center for
Environmental Assessment, by mail at
U.S. EPA (8601D), 1200 Pennsylvania
Avenue, NW., Washington, DC 20460;
by phone at 202–564–2060; by facsimile
at 202–565–0075; or by e-mail at
jones.samantha@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Summary of Information About the
Integrated Risk Information System
(IRIS)
IRIS is a database that contains
potential adverse human health effects
information that may result from
chronic (or lifetime) exposure to specific
chemical substances found in the
environment. The database (available on
the Internet at https://www.epa.gov/iris)
contains qualitative and quantitative
health effects information for more than
500 chemical substances that may be
used to support the first two steps
(hazard identification and doseresponse evaluation) of a risk
assessment process. When supported by
available data, the database provides
oral reference doses (RfDs) and
inhalation reference concentrations
(RfCs) for chronic health effects, and
oral slope factors and inhalation unit
risks for carcinogenic effects. Combined
with specific exposure information,
government and private entities can use
IRIS to help characterize public health
risks of chemical substances in a sitespecific situation and thereby support
risk management decisions designed to
protect public health.
II. Workshop Information
Members of the public may attend the
workshop as observers, and there will
be a limited time for comments from the
PO 00000
Frm 00057
Fmt 4703
Sfmt 4703
public. Please let ORISE know if you
wish to make oral comments during the
workshop prior to the meeting. Space is
limited, and reservations will be
accepted on a first-come, first-served
basis.
III. How to Submit Technical
Comments to the Docket at
www.regulations.gov
Submit your comments, identified by
Docket ID No. EPA–HQ–ORD 2006–
0838 by one of the following methods:
• https://www.regulations.gov: Follow
the on-line instructions for submitting
comments.
• E-mail: ORD.Docket@epa.gov.
• Fax: 202–566–1753.
• Mail: Office of Environmental
Information (OEI) Docket (Mail Code:
2822T), U.S. Environmental Protection
Agency, 1200 Pennsylvania Ave., NW.,
Washington, DC 20460. The phone
number is 202–566–1752.
• Hand Delivery: The OEI Docket is
located in the EPA Headquarters Docket
Center, EPA West Building, Room 3334,
1301 Constitution Ave., NW.,
Washington, DC. The EPA Docket
Center Public Reading Room is open
from 8:30 a.m. to 4:30 p.m., Monday
through Friday, excluding legal
holidays. The telephone number for the
Public Reading Room is 202–566–1744.
Such deliveries are only accepted
during the Docket’s normal hours of
operation, and special arrangements
should be made for deliveries of boxed
information. Consult EPA’s Web site at
https://www.epa.gov/epahome/
dockets.htm for current information on
docket operations, locations and
telephone numbers.
If you provide comments by mail or
hand delivery, please submit one
unbound original with pages numbered
consecutively, and three copies of the
comments. For attachments, provide an
index, number pages consecutively with
the comments, and submit an unbound
original and three copies.
Instructions: Direct your comments to
Docket ID No. EPA-HQ-ORD–2006–
0838. Please ensure that your comments
are submitted within the specified
comment period. Comments received
after the closing date will be marked
‘‘late,’’ and may only be considered if
time permits. It is EPA’s policy to
include all comments it receives in the
public docket without change and to
make the comments available online at
https://www.regulations.gov, including
any personal information provided,
unless a comment includes information
claimed to be Confidential Business
Information (CBI) or other information
whose disclosure is restricted by statute.
Do not submit information that you
E:\FR\FM\22DEN1.SGM
22DEN1
77017
Federal Register / Vol. 71, No. 246 / Friday, December 22, 2006 / Notices
consider to be CBI or otherwise
protected through www.regulations.gov
or e-mail. The www.regulations.gov
Web site is an ‘‘anonymous access’’
system, which means EPA will not
know your identity or contact
information unless you provide it in the
body of your comment. If you send an
e-mail comment directly to EPA without
going through www.regulations.gov,
your e-mail address will be
automatically captured and included as
part of the comment that is placed in the
public docket and made available on the
Internet. If you submit an electronic
comment, EPA recommends that you
include your name and other contact
information in the body of your
comment and with any disk or CD-ROM
you submit. If EPA cannot read your
comment due to technical difficulties
and cannot contact you for clarification,
EPA may not be able to consider your
comment. Electronic files should avoid
the use of special characters, any form
of encryption, and be free of any defects
or viruses. For additional information
about EPA’s public docket visit the EPA
Docket Center homepage at https://
www.epa.gov/epahome/dockets.htm.
Docket: Documents in the docket are
listed in the www.regulations.gov
index. Although listed in the index,
some information is not publicly
available, e.g. CBI or other information
whose disclosure is restricted by statute.
Certain other materials, such as
copyrighted material, are publicly
available only in hard copy. Publicly
available docket materials are available
either electronically in
www.regulations.gov or in hard copy at
the OEI Docket in the EPA Headquarters
Docket Center.
Dated: December 14, 2006.
George Alapas,
Deputy Director, National Center for
Environmental Assessment.
[FR Doc. E6–21969 Filed 12–21–06; 8:45 am]
BILLING CODE 6560–50–P
ENVIRONMENTAL PROTECTION
AGENCY
[FRL–8260–2; Docket ID No. EPA–HQ–ORD–
2006–0950]
Integrated Risk Information System
(IRIS); Request for Chemical
Substance Nominations for 2007
Program
Environmental Protection
Agency (EPA).
ACTION: Request for chemical substance
nominations for the IRIS 2007 program.
jlentini on PROD1PC65 with NOTICES
AGENCY:
SUMMARY: The Integrated Risk
Information System (IRIS) is an
VerDate Aug<31>2005
17:45 Dec 21, 2006
Jkt 211001
Environmental Protection Agency (EPA)
database that contains EPA’s scientific
positions on human health effects that
may result from exposure to chemical
substances in the environment. EPA is
soliciting public nominations for
chemical substances for its 2007 agenda.
EPA invites the public to submit
nominations for substances to be
considered for an assessment or
reassessment in its IRIS Program in
accordance with the instructions
provided at the end of this notice.
DATES: Nominations must be submitted
within 30 days of the publication of this
notice. The 30-day period begins
December 22, 2006 and ends January 22,
2007.
ADDRESSES: Nominations may be
submitted electronically via
www.regulations.gov, by mail, by
facsimile, or by hand delivery/courier.
Please follow the detailed instructions
provided in the SUPPLEMENTARY
INFORMATION section of this notice.
FOR FURTHER INFORMATION CONTACT: For
information on the IRIS Program,
contact Abdel Kadry, Ph.D., Program
Director, National Center for
Environmental Assessment (mail code
8601D), Office of Research and
Development, U.S. Environmental
Protection Agency, Washington, DC
20460, or call (202) 564–1645, or send
electronic mail inquiries to:
kadry.abdel@epa.gov. For general
questions about access to IRIS or the
content of IRIS, please call the IRIS
Hotline at (301) 345–2870 or send
electronic mail inquiries to
hotline.iris@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Background
IRIS is an EPA database containing
EPA consensus scientific positions on
potential adverse human health effects
that might result from exposure to
chemical substances found in the
environment. IRIS currently provides
information on health effects associated
with more than 500 chemical
substances. The database includes
chemical-specific summaries of
qualitative and quantitative health
information in support of the first two
steps of the risk assessment process, i.e.,
hazard identification and dose-response
evaluation. Combined with specific
situational exposure assessment
information, the information in IRIS
may be used as a source in evaluating
potential public health risks from
environmental contaminants.
EPA’s overall process for developing
IRIS assessments consists of: (1) An
annual Federal Register announcement
of EPA’s IRIS agenda and call for
PO 00000
Frm 00058
Fmt 4703
Sfmt 4703
scientific information from the public
on selected chemical substances; (2) a
search of the current literature; (3)
development of draft health assessments
and IRIS summaries; (4) peer review
within EPA and the Federal
Government; (5) external peer review;
(6) management approval; (7)
preparation of final IRIS summaries and
supporting documents; and (8) entry of
summaries and supporting documents
into the IRIS database.
A. The IRIS Annual Agenda
Each year, EPA develops a list of
priority chemical substances and an
annual agenda for the IRIS Program.
EPA uses the following general criteria
to set these priorities: (1) EPA statutory,
regulatory, or program-specific
implementation needs; (2) potential
public health impact; (3) availability of
new scientific information or
methodology that might significantly
change the current IRIS information; (4)
interest to other levels of government or
the public; and (5) availability of other
scientific assessment documents such
that only a modest additional effort
would be needed to complete the review
and documentation for IRIS. The
decision to assess any given substance
depends on available EPA resources.
Timing of EPA’s risk assessment
guidance, guidelines, and science policy
decisions may also play a role in
deciding when the Agency has the
appropriate methods to assess a
chemical substance.
EPA continues to build and update
the IRIS database by addressing the
foremost user needs, as expressed by
EPA, other federal agencies, and the
public. EPA also works toward updating
all assessments in the database where
new scientific information is available
to do so.
EPA is currently conducting the
following 80 assessments. Unless
otherwise noted, EPA expects to assess
noncancer and cancer endpoints for
each substance. For all endpoints
assessed, EPA intends to develop both
qualitative and quantitative assessments
if adequate data are available to support
those assessments.
Substance name
Acetaldehyde ............
Acrolein (acute exposure duration).
Acrylamide ................
Acrylonitrile ................
Aldicarb and aldicarb
sulfoxide.
Aldicarb sulfone ........
Arsenic, inorganic .....
Asbestos (noncancer
and cancer effects).
E:\FR\FM\22DEN1.SGM
22DEN1
CAS no.
75–07–0
107–02–8
79–06–1
107–13–1
116–06–3/1646–87–3
1646–88–4
7440–38–2
1332–21–4
Agencies
[Federal Register Volume 71, Number 246 (Friday, December 22, 2006)]
[Notices]
[Pages 77015-77017]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E6-21969]
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
[FRL-8260-3; Docket ID No. EPA-HQ-ORD-2006-0838]
Draft Toxicological Reviews of Polybrominated Diphenyl Ethers
(PBDEs): In support of the Summary Information in the Integrated Risk
Information System (IRIS)
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of External Peer-Review Panel Meeting and Public Comment
Period.
-----------------------------------------------------------------------
SUMMARY: EPA is announcing that the Oak Ridge Institute of Science and
Education (ORISE), under an Interagency agreement between the
Department of Energy and EPA, will convene an independent panel of
experts and organize and conduct an external peer-review workshop to
review the external review draft documents titled, ``Toxicological
Review of TetraBDE (BDE-47): In Support of Summary Information in the
Integrated Risk Information System (IRIS)'' (NCEA-S-2537);
``Toxicological Review of PentaBDE (BDE-99): In Support of Summary
Information in the Integrated Risk Information System (IRIS)'' (NCEA-S-
2538); ``Toxicological Review of HexaBDE (BDE-153): In Support of
Summary Information in the Integrated Risk Information System (IRIS)''
(NCEA-S-2539); and ``Toxicological Review of DecaBDE (BDE-209): In
Support of Summary Information in the Integrated Risk Information
System (IRIS)'' (NCEA-S-2540). The EPA also is announcing a public
comment period for the external review draft documents.
The public comment period and the external peer-review workshop are
separate processes that provide opportunities for all interested
parties to comment on the document. In addition to consideration by
EPA, all public comments submitted in accordance with this notice will
also be forwarded to ORISE for consideration by the external peer-
review panel prior to the workshop.
EPA is releasing these draft documents solely for the purpose of
pre-dissemination peer review under applicable information quality
guidelines. These documents have not been formally disseminated by EPA.
They do not represent and should not be construed to represent any
Agency policy or determination. ORISE invites the public to register to
attend this workshop as observers. In addition, ORISE invites the
public to give brief
[[Page 77016]]
oral comments at the workshop regarding the draft documents under
review. The draft documents and EPA's peer-review charge are available
via the Internet on NCEA's home page under the Recent Additions and the
Publications menus at https://www.epa.gov/ncea. When finalizing the
draft documents, EPA will consider ORISE's report of the comments and
recommendations from the external peer-review workshop and any public
comments that EPA receives in accordance with this notice.
DATES: The external peer-review panel workshop will begin on February
22, 2007, at 9 a.m. and end at 4 p.m. The public comment period begins
December 22, 2006 and ends February 5, 2007. Technical comments should
be in writing and must be received by EPA by February 5, 2007. Comments
from the public received by this date will be submitted to the external
peer-review panel prior to the workshop.
ADDRESSES: The external peer-review workshop will be held at The
American Geophysical Union, 2000 Florida Avenue NW., Washington, DC,
20009-1277. ORISE is organizing, convening, and conducting the peer-
review workshop. To attend the workshop, register by February 8, 2007,
via the Internet at https://www.orau.gov/pbde. You may also register by
calling ORISE at 865-576-2922, sending a facsimile to 865-241-3168, or
sending an e-mail to Margaret Lyday at lydaym@orau.gov. You must
register by February 8, 2007, if you wish to provide brief oral
comments at the workshop.
The draft documents, Toxicological Review of TetraBDE (BDE-47): In
Support of Summary Information in the Integrated Risk Information
System (IRIS); PentaBDE (BDE-99): In Support of Summary Information in
the Integrated Risk Information System (IRIS); HexaBDE (BDE-153): In
Support of Summary Information in the Integrated Risk Information
System (IRIS); and DecaBDE (BDE-209): In Support of Summary Information
in the Integrated Risk Information System (IRIS), are available via the
Internet on the National Center for Environmental Assessment's (NCEA)
home page under the Recent Additions and the Publications menus at
https://www.epa.gov/ncea. A limited number of paper copies are available
from NCEA's Technical Information Staff. Please contact the Technical
Information Staff by telephone at 202-564-3261 or by facsimile at 202-
565-0050. If you are requesting a paper copy, please provide your name,
mailing address, and the document title. Copies are not available from
ORISE.
Comments may be submitted electronically via www.regulations.gov,
by mail, by facsimile, or by hand delivery/courier. Please follow the
detailed instructions as provided in the SUPPLEMENTARY INFORMATION
section of this notice.
FOR FURTHER INFORMATION CONTACT: For information on the peer review
workshop, contact Margaret Lyday, ORISE, by mail at P.O. Box 117, MS
17, Oak Ridge, TN 37831-0117; by phone at 865-576-2922; by facsimile at
865-241-3168; or by e-mail at lydaym@orau.gov.
For information on the public comment period, contact the Office of
Environmental Information Docket; by phone at 202-566-1752; by
facsimile at 202-566-1753; or by e-mail at ORD.Docket@epa.gov.
If you have questions about the document, contact Samantha J.
Jones, IRIS Staff, National Center for Environmental Assessment, by
mail at U.S. EPA (8601D), 1200 Pennsylvania Avenue, NW., Washington, DC
20460; by phone at 202-564-2060; by facsimile at 202-565-0075; or by e-
mail at jones.samantha@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Summary of Information About the Integrated Risk Information System
(IRIS)
IRIS is a database that contains potential adverse human health
effects information that may result from chronic (or lifetime) exposure
to specific chemical substances found in the environment. The database
(available on the Internet at https://www.epa.gov/iris) contains
qualitative and quantitative health effects information for more than
500 chemical substances that may be used to support the first two steps
(hazard identification and dose-response evaluation) of a risk
assessment process. When supported by available data, the database
provides oral reference doses (RfDs) and inhalation reference
concentrations (RfCs) for chronic health effects, and oral slope
factors and inhalation unit risks for carcinogenic effects. Combined
with specific exposure information, government and private entities can
use IRIS to help characterize public health risks of chemical
substances in a site-specific situation and thereby support risk
management decisions designed to protect public health.
II. Workshop Information
Members of the public may attend the workshop as observers, and
there will be a limited time for comments from the public. Please let
ORISE know if you wish to make oral comments during the workshop prior
to the meeting. Space is limited, and reservations will be accepted on
a first-come, first-served basis.
III. How to Submit Technical Comments to the Docket at
www.regulations.gov
Submit your comments, identified by Docket ID No. EPA-HQ-ORD 2006-
0838 by one of the following methods:
https://www.regulations.gov: Follow the on-line
instructions for submitting comments.
E-mail: ORD.Docket@epa.gov.
Fax: 202-566-1753.
Mail: Office of Environmental Information (OEI) Docket
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
Hand Delivery: The OEI Docket is located in the EPA
Headquarters Docket Center, EPA West Building, Room 3334, 1301
Constitution Ave., NW., Washington, DC. The EPA Docket Center Public
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through
Friday, excluding legal holidays. The telephone number for the Public
Reading Room is 202-566-1744. Such deliveries are only accepted during
the Docket's normal hours of operation, and special arrangements should
be made for deliveries of boxed information. Consult EPA's Web site at
https://www.epa.gov/epahome/dockets.htm for current
information on docket operations, locations and telephone numbers.
If you provide comments by mail or hand delivery, please submit one
unbound original with pages numbered consecutively, and three copies of
the comments. For attachments, provide an index, number pages
consecutively with the comments, and submit an unbound original and
three copies.
Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2006-0838. Please ensure that your comments are submitted within the
specified comment period. Comments received after the closing date will
be marked ``late,'' and may only be considered if time permits. It is
EPA's policy to include all comments it receives in the public docket
without change and to make the comments available online at https://
www.regulations.gov, including any personal information provided,
unless a comment includes information claimed to be Confidential
Business Information (CBI) or other information whose disclosure is
restricted by statute. Do not submit information that you
[[Page 77017]]
consider to be CBI or otherwise protected through www.regulations.gov
or e-mail. The www.regulations.gov Web site is an ``anonymous access''
system, which means EPA will not know your identity or contact
information unless you provide it in the body of your comment. If you
send an e-mail comment directly to EPA without going through
www.regulations.gov, your e-mail address will be automatically captured
and included as part of the comment that is placed in the public docket
and made available on the Internet. If you submit an electronic
comment, EPA recommends that you include your name and other contact
information in the body of your comment and with any disk or CD-ROM you
submit. If EPA cannot read your comment due to technical difficulties
and cannot contact you for clarification, EPA may not be able to
consider your comment. Electronic files should avoid the use of special
characters, any form of encryption, and be free of any defects or
viruses. For additional information about EPA's public docket visit the
EPA Docket Center homepage at https://www.epa.gov/epahome/
dockets.htm.
Docket: Documents in the docket are listed in the
www.regulations.gov index. Although listed in the index, some
information is not publicly available, e.g. CBI or other information
whose disclosure is restricted by statute. Certain other materials,
such as copyrighted material, are publicly available only in hard copy.
Publicly available docket materials are available either electronically
in www.regulations.gov or in hard copy at the OEI Docket in the EPA
Headquarters Docket Center.
Dated: December 14, 2006.
George Alapas,
Deputy Director, National Center for Environmental Assessment.
[FR Doc. E6-21969 Filed 12-21-06; 8:45 am]
BILLING CODE 6560-50-P