A Framework for Assessing Health Risks of Environmental Exposures to Children, 60514 [E6-16911]

Download as PDF 60514 Federal Register / Vol. 71, No. 198 / Friday, October 13, 2006 / Notices Dated: October 5, 2006. Lois Rossi, Director, Registration Division, Office of Pesticide Programs. [FR Doc. E6–17010 Filed 8–12–06; 8:45 am] BILLING CODE 6560–50–S ENVIRONMENTAL PROTECTION AGENCY [FRL–8230–5] A Framework for Assessing Health Risks of Environmental Exposures to Children Environmental Protection Agency (EPA). ACTION: Notice of availability. AGENCY: SUMMARY: EPA is announcing the availability of a final report titled, ‘‘A Framework for Assessing Health Risks of Environmental Exposures to Children’’ (EPA/600/R–05/093F), prepared by the National Center for Environmental Assessment (NCEA) within EPA’s Office of Research and Development (ORD). DATES: This document will be available on or about October 13, 2006. ADDRESSES: The document will be available electronically through the NCEA Web site at www.epa.gov/ncea. A limited number of paper copies will be available from the EPA’s National Service Center for Environmental Publications (NSCEP), P.O. Box 42419, Cincinnati, OH 45242; telephone: 1– 800–490–9198 or 513–489–8190; facsimile: 513–489–8695. Please provide your name, your mailing address, the title and the EPA number of the requested publication. FOR FURTHER INFORMATION CONTACT: The Technical Information Staff, National Center for Environmental Assessment/ Washington Office (8623D), U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone: 202– 564–3261; fax: 202–565–0050; e-mail: nceadc.comment@epa.gov. The purpose of this report is to provide an overarching framework for a complete and transparent assessment of exposure of environmental agents to children and resulting potential health risks within the U.S. EPA’s risk assessment paradigm. This Framework builds on the Agency’s past experience in evaluating risk to children. This Framework lays out a life stage-specific risk assessment process, points to existing published sources for more detailed information on life stage- ycherry on PROD1PC64 with NOTICES2 SUPPLEMENTARY INFORMATION: VerDate Aug<31>2005 15:21 Oct 12, 2006 Jkt 211001 specific considerations, and includes Web links to specific online publications and relevant Agency science policy papers, guidelines and guidance. This Framework emphasizes the need for risk assessments to take into account potential exposures to environmental agents during preconception and all stages of development. This Framework is not intended to present an Agency guideline, but rather describes the overall structure of and the components considered important for children’s health risk assessment. The report describes an approach that includes problem formulation, analysis, and risk characterization steps, and also builds on Agency experience assessing risk to susceptible populations. • Problem Formulation—Focuses on the life stage-specific nature of the analysis to include scoping and screening level questions for hazard characterization, dose response and exposure assessment. • Analysis—Focuses on a life stage approach to evaluating hazard, doseresponse and exposure that is relevant to the scope of the problem identified in problem formulation. • Risk Characterization—Recognizes the need to consider life stage-specific risks and explicitly describes the uncertainties and variability in the database. It is important to note that within this framework, life stage-specific data gaps are not meant to convey an obligatory change in how uncertainty factor(s) associated with EPA’s health risk assessment methods should be judged in a given risk assessment, but rather to consider how life stage-specific data can better characterize the risk to susceptible groups within the population. The peer review panel report, the public comments, and the response to peer review and public comments will also be available at the same time. Dated: September 14, 2006. George Alapas, Acting Director, National Center for Environmental Assessment. [FR Doc. E6–16911 Filed 10–12–06; 8:45 am] BILLING CODE 6560–50–P ENVIRONMENTAL PROTECTION AGENCY EPA–HQ–OPPT–2006–0808; FRL–8098–3 Certain New Chemicals; Receipt and Status Information Environmental Protection Agency (EPA). AGENCY: PO 00000 Frm 00054 Fmt 4703 Sfmt 4703 ACTION: Notice. SUMMARY: Section 5 of the Toxic Substances Control Act (TSCA) requires any person who intends to manufacture (defined by statute to include import) a new chemical (i.e., a chemical not on the TSCA Inventory) to notify EPA and comply with the statutory provisions pertaining to the manufacture of new chemicals. Under sections 5(d)(2) and 5(d)(3) of TSCA, EPA is required to publish a notice of receipt of a premanufacture notice (PMN) or an application for a test marketing exemption (TME), and to publish periodic status reports on the chemicals under review and the receipt of notices of commencement to manufacture those chemicals. This status report, which covers the period from August 28, 2006 to September 8, 2006, consists of the PMNs pending or expired, and the notices of commencement to manufacture a new chemical that the Agency has received under TSCA section 5 during this time period. DATES: Comments identified by the specific PMN number or TME number, must be received on or before November 13, 2006. ADDRESSES: Submit your comments, identified by docket identification (ID) no. EPA–HQ–OPPT–2006–0808, by one of the following methods. • http://www.regulations.gov. Follow the on-line instructions for submitting comments. • Mail: Document Control Office (7407M), Office of Pollution Prevention and Toxics (OPPT), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460– 0001. • Hand Delivery: OPPT Document Control Office (DCO, EPA East Bldg., Rm. 6428, 1201 Constitution Ave., NW., Washington, DC. Attention: Docket ID number EPA–HQ–OPPT–2006–0767. The DCO is open from 8 a.m. to 4 p.m., Monday through Friday, excluding legal holidays. The telephone number for the DCO is (202) 564–8930. Such deliveries are only accepted during the Docket’s normal hours of operation, and special arrangements should be made for deliveries of boxed information. • Instructions: Direct your comments to docket ID number EPA–HQ–OPPT– 2006–0808. EPA’s policy is that all comments received will be included in the public docket without change and may be made available online at http:// www.regulations.gov, including any personal information provided, unless the comment includes information claimed to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. E:\FR\FM\13OCN1.SGM 13OCN1

Agencies

[Federal Register Volume 71, Number 198 (Friday, October 13, 2006)]
[Notices]
[Page 60514]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E6-16911]


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ENVIRONMENTAL PROTECTION AGENCY

 [FRL-8230-5]


A Framework for Assessing Health Risks of Environmental Exposures 
to Children

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of availability.

-----------------------------------------------------------------------

SUMMARY: EPA is announcing the availability of a final report titled, 
``A Framework for Assessing Health Risks of Environmental Exposures to 
Children'' (EPA/600/R-05/093F), prepared by the National Center for 
Environmental Assessment (NCEA) within EPA's Office of Research and 
Development (ORD).

DATES: This document will be available on or about October 13, 2006.

ADDRESSES: The document will be available electronically through the 
NCEA Web site at www.epa.gov/ncea. A limited number of paper copies 
will be available from the EPA's National Service Center for 
Environmental Publications (NSCEP), P.O. Box 42419, Cincinnati, OH 
45242; telephone: 1-800-490-9198 or 513-489-8190; facsimile: 513-489-
8695. Please provide your name, your mailing address, the title and the 
EPA number of the requested publication.

FOR FURTHER INFORMATION CONTACT: The Technical Information Staff, 
National Center for Environmental Assessment/Washington Office (8623D), 
U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW., 
Washington, DC 20460; telephone: 202-564-3261; fax: 202-565-0050; e-
mail: nceadc.comment@epa.gov.

SUPPLEMENTARY INFORMATION: The purpose of this report is to provide an 
overarching framework for a complete and transparent assessment of 
exposure of environmental agents to children and resulting potential 
health risks within the U.S. EPA's risk assessment paradigm. This 
Framework builds on the Agency's past experience in evaluating risk to 
children. This Framework lays out a life stage-specific risk assessment 
process, points to existing published sources for more detailed 
information on life stage-specific considerations, and includes Web 
links to specific online publications and relevant Agency science 
policy papers, guidelines and guidance. This Framework emphasizes the 
need for risk assessments to take into account potential exposures to 
environmental agents during preconception and all stages of 
development. This Framework is not intended to present an Agency 
guideline, but rather describes the overall structure of and the 
components considered important for children's health risk assessment.
    The report describes an approach that includes problem formulation, 
analysis, and risk characterization steps, and also builds on Agency 
experience assessing risk to susceptible populations.
     Problem Formulation--Focuses on the life stage-specific 
nature of the analysis to include scoping and screening level questions 
for hazard characterization, dose response and exposure assessment.
     Analysis--Focuses on a life stage approach to evaluating 
hazard, dose-response and exposure that is relevant to the scope of the 
problem identified in problem formulation.
     Risk Characterization--Recognizes the need to consider 
life stage-specific risks and explicitly describes the uncertainties 
and variability in the database.
    It is important to note that within this framework, life stage-
specific data gaps are not meant to convey an obligatory change in how 
uncertainty factor(s) associated with EPA's health risk assessment 
methods should be judged in a given risk assessment, but rather to 
consider how life stage-specific data can better characterize the risk 
to susceptible groups within the population.
    The peer review panel report, the public comments, and the response 
to peer review and public comments will also be available at the same 
time.

    Dated: September 14, 2006.
George Alapas,
Acting Director, National Center for Environmental Assessment.
 [FR Doc. E6-16911 Filed 10-12-06; 8:45 am]
BILLING CODE 6560-50-P