Draft Toxicological Review of Dichlorobenzenes: In Support of Summary Information on the Integrated Risk Information System (IRIS), 60139-60141 [E6-16925]
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Federal Register / Vol. 71, No. 197 / Thursday, October 12, 2006 / Notices
C = D × (.95 ¥ LPF) × $0.10
with the factors defined as follows:
C = The charge in dollars to be assessed for
any particular Demand Period of such
month that the Determination of Power
Factor ‘‘PF’’ is calculated to be less than
95 percent lagging.
D = The Customer’s demand in kilowatts at
the point of delivery for such Demand
Period in which a low power factor was
calculated.
LPF = The lagging power factor, if any,
determined by the formula ‘‘PF’’ for such
Demand Period.
If C is negative, then C = zero (0).
Application of Power Factor Penalty
The Power Factor Penalty is
applicable to radial interconnections
with the System of Southwestern. The
total Power Factor Penalty for any
month shall be the sum of all charges
‘‘C’’ for all Demand Periods of such
month. No penalty is assessed for
leading power factor. Southwestern, in
its sole judgment and at its sole option,
may determine whether power factor
calculations should be applied to a
single physical point of delivery or to
multiple physical points of delivery
where a Customer has a single,
electrically integrated load served
through multiple points or
interconnections. The general criteria
for such decision shall be that, given the
configuration of the Customer’s and
Southwestern’s systems, Southwestern
will determine, in its sole judgment and
at its sole option, whether the power
factor calculation more accurately
assesses the detrimental impact on
Southwestern’s system when the above
formula is calculated for a single
physical point of delivery or for a
combination of physical points or for an
interconnection as specified by an
Interconnection Agreement.
Southwestern, at its sole option, may
reduce or waive power factor penalties
when, in Southwestern’s sole judgment,
low power factor conditions were not
detrimental to the System of
Southwestern due to particular loading
and voltage conditions at the time the
power factor dropped below 95 percent
lagging.
Department of Energy, Southwestern
Power Administration
rwilkins on PROD1PC63 with NOTICES
Rate Schedule EE–06 1 Wholesale Rate
for Excess Energy
Effective: During the period October 1,
2006, through September 30, 2010, in
accordance with Rate Order No. SWPA–
56 issued by the Deputy Secretary of
Energy.
1 Supersedes
VerDate Aug<31>2005
Rate Schedule EE–05.
16:21 Oct 11, 2006
Jkt 211001
Available: In the marketing area of
Southwestern Power Administration
(Southwestern), described generally as
the States of Arkansas, Kansas,
Louisiana, Missouri, Oklahoma, and
Texas.
Applicable: To electric utilities
which, by contract, may purchase
Excess Energy from Southwestern.
Character and Conditions of Service:
Three-phase, alternating current,
delivered at approximately 60 Hertz, at
the nominal voltage and points of
delivery specified by contract.
Energy Associated with this Rate
Schedule: Excess Energy will be
furnished at such times and in such
amounts as Southwestern determines to
be available.
Transmission and Related Ancillary
Services: Transmission service for the
delivery of Excess Energy shall be the
sole responsibility of such customer
purchasing Excess Energy.
Rate for Excess Energy:
Energy Charge:
10/1/2006–9/30/2007
10/1/2007–9/30/2010
$0.0055 per
kilowatthour.
$0.0082 per
kilowatthour.
[FR Doc. E6–16912 Filed 10–11–06; 8:45 am]
BILLING CODE 6450–01–P
ENVIRONMENTAL PROTECTION
AGENCY
[FRL–8230–6; Docket ID No. EPA–HQ–ORD–
2004–0002]
Draft Toxicological Review of
Dichlorobenzenes: In Support of
Summary Information on the
Integrated Risk Information System
(IRIS)
Environmental Protection
Agency (EPA).
ACTION: Notice of Extension of Public
Comment Period, Rescheduled External
Peer Review Panel Meeting, and
Meeting Format Change.
AGENCY:
SUMMARY: The EPA is extending the
public comment period and
rescheduling an external peer review
panel meeting to review selected
sections of the EPA National Center for
Environmental Assessment (NCEA) final
draft document titled, ‘‘Toxicological
Review of Dichlorobenzenes: In Support
of Summary Information on the
Integrated Risk Information System
(IRIS)’’ (EPA/635/R–03/015), regarding
the inhalation reference concentration
(RfC) and inhalation cancer assessment
for 1,4-dichlorobenzene. The EPA is
also changing the format of this external
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60139
peer review meeting to include both a
teleconference and an in-person panel
meeting.
On July 11, 2006, EPA published a
Federal Register notice (71 FR 39113)
announcing a comment period that
ended August 9 and an external peer
review panel meeting (by
teleconference) that was scheduled for
August 16. On August 11, 2006, EPA
published a second Federal Register
notice announcing an extension of the
public comment period to October 10
and a rescheduling of the external peer
review meeting to October 30. EPA is
extending the public comment period to
October 17, 2006, rescheduling the
external peer review meeting to
November 3, 2006, and changing the
format to include both a face-to-face
meeting and a teleconference option for
participation. This extended public
comment period and change in format
for the external peer review are in
response to requests from the public.
The public comment period and the
external peer review meeting are
separate processes that provide
opportunities for all interested parties to
comment on the document. In addition
to consideration by EPA, all public
comments submitted in accordance with
this notice will also be forwarded to
EPA’s contractor, the Oak Ridge
Institute for Science and Education
(ORISE), for consideration by the
external peer review panel prior to the
meeting.
As previously stated in 71 FR 39113
and 71 FR 46220, EPA is releasing this
draft document solely for the purpose of
pre-dissemination peer review under
applicable information quality
guidelines. This document has not been
formally disseminated by EPA. It does
not represent and should not be
construed to represent any Agency
policy or determination.
ORISE invites the public to register to
attend this peer review panel meeting as
observers, either in person or by
telephone. In addition, ORISE invites
the public to give brief oral comments
at the meeting regarding the draft
document under review. The draft
document and EPA’s peer review charge
are available via the Internet on NCEA’s
home page under the Recent Additions
menu at https://www.epa.gov/ncea.
When finalizing this draft report, EPA
will consider ORISE’s report of the
comments and recommendations from
the external peer reviewers and any
public comments that EPA receives in
accordance with this notice.
DATES: The period for submission of
comments on the final draft document
will end on October 17, 2006. Technical
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60140
Federal Register / Vol. 71, No. 197 / Thursday, October 12, 2006 / Notices
comments should be in writing and
must be received by EPA by October 17,
2006. Comments submitted to the EPA
by October 17, 2006, will be provided to
the external peer review panel prior to
the panel review meeting. The peer
review will be on November 3, 2006,
and will begin at 9 a.m. and end
approximately at 1 p.m., eastern time.
ADDRESSES: The external peer review
panel meeting will be held at the
American Geophysical Union, 2000
Florida Avenue, NW., Washington, DC
20009–1277. Under an Interagency
Agreement between EPA and the
Department of Energy, the Oak Ridge
Institute of Science and Education
(ORISE) is organizing, convening, and
conducting the peer review panel
meeting. To attend the meeting, register
by October 17, 2006, by calling ORISE
at (865) 576–2922, sending a facsimile
to (865) 241–3168, or sending an e-mail
to Margaret Lyday at lydaym@orau.gov.
Interested parties may also register via
the Internet at https://www.orau.gov/
dichlorobenzene. You must register by
October 17, 2006, if you wish to provide
brief oral comments or if you plan to use
the teleconference option at the peer
review panel meeting.
The draft ‘‘Toxicological Review of
Dichlorobenzenes: In Support of
Summary Information on the Integrated
Risk Information System (IRIS)’’ (EPA/
635/R–03/015) is available primarily via
the Internet on NCEA’s home page
under the Recent Additions menu at
https://www.epa.gov/ncea. A limited
number of paper copies are available by
contacting the IRIS Hotline at (202) 566–
1676, (202) 566–1749 (facsimile), or
hotline.iris@epa.gov. If you are
requesting a paper copy, please provide
your name, mailing address, the
document title, and the EPA number of
the requested publication. Copies are
not available from ORISE.
Copies of the study by Aiso et al.
(2005), referenced in the SUPPLEMENTARY
INFORMATION section of this notice, are
available from the IRIS Hotline in paper
or electronic format or via the docket at
https://www.regulations.gov. If you are
requesting a copy from the IRIS Hotline,
please provide your name, mailing
address or e-mail address, and
document citation: Aiso et al. (2005)
Carcinogenicity and chronic toxicity in
mice and rats exposed by inhalation to
parA–dichlorobenzene for two years. J
Vet Med Sci 67(10):1019–1029. EPA is
providing this study in the interest of
transparency. EPA is not endorsing or
supporting the study or its findings.
Technical comments may be
submitted electronically via https://
www.regulations.gov, by mail, by
VerDate Aug<31>2005
16:21 Oct 11, 2006
Jkt 211001
facsimile, or by hand delivery/courier.
Please follow the detailed instructions
provided in the SUPPLEMENTARY
INFORMATION section of this notice.
FOR FURTHER INFORMATION CONTACT:
Questions regarding registration and
logistics for the external peer review
panel meeting and teleconference
should be directed to Margaret Lyday,
ORISE, P.O. Box 117, MS 17, Oak Ridge,
TN 37831–0117, at (865) 576–2922,
(865) 241–3168 (facsimile), or
lydaym@orau.gov (e-mail).
If you have questions about the
document, contact Audrey Galizia,
Chemical Manager, National Center for
Environmental Assessment; telephone:
(732) 906–6887; facsimile: (732) 452–
6429; e-mail: galizia.audrey@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Information About the Document
IRIS is a database that contains
Agency scientific positions on potential
adverse human health effects that may
result from chronic (or lifetime)
exposure to specific chemical
substances found in the environment.
The database (available on the Internet
at https://www.epa.gov/iris) contains
qualitative and quantitative health
effects information for more than 500
chemical substances that may be used to
support the first two steps (hazard
identification and dose-response
evaluation) of the risk assessment
process. When supported by available
data, the database can be used as a
resource for oral reference doses (RfDs)
and inhalation reference concentrations
(RfCs) for chronic health effects, and
oral slope factors and inhalation unit
risks for carcinogenic effects. Combined
with specific exposure information,
government and private entities use IRIS
to help characterize public health risks
of chemical substances in a site-specific
situation and thereby support risk
management decisions designed to
protect public health.
1,4-Dichlorobenzene is widely used as
a space deodorant for toilets and refuse
containers, as a moth repellent in moth
balls or crystals, and in other pesticide
applications. The current IRIS
assessment for 1,4-dichlorobenzene was
placed on the database in 1994 and
contains an inhalation RfC. A
reassessment of the potential health
effects of dichlorobenzenes has been
undertaken. The draft assessment for
dichlorobenzenes (including the 1,2-,
1,3-, and 1,4-isomers) was subject to an
external peer review and 30-day public
comment period in February 2004 (69
FR 4514, January 30, 2004). The scope
of the current external peer review and
public comment is limited to the
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analyses based on a chronic inhalation
bioassay of 1,4-dichlorobenzene
published in the peer-reviewed
literature (Aiso et al., 2005. J Vet Med
Sci 67(10):1019–29) that was not
included in the February 2004 external
peer review draft. This study was
identified originally as an unpublished
study report by the Japan Bioassay
Research Center (JBRC, 1995). Data from
Aiso et al. (2005) were used
subsequently in the quantitative doseresponse assessments for the 1,4dichlorobenzene RfC and inhalation
cancer assessment.
II. Panel Meeting Information
Members of the public may attend the
panel meeting as observers, and there
will be a limited time for comments
from the public. To make oral comments
at the commencement of the peer review
meeting, you must pre-register with
ORISE indicating your intent to do so.
Space is limited, and reservations will
be accepted on a first-come, first-served
basis.
III. How to Submit Technical
Comments to the Docket at https://
www.regulations.gov
Note: The EPA Docket Center suffered
damage due to flooding during the last week
of June 2006. The Docket Center is
continuing to operate. However, during the
cleanup, there will be temporary changes to
Docket Center telephone numbers, addresses,
and hours of operation for people who wish
to make hand deliveries or visit the Public
Reading Room to view documents. Consult
EPA’s Federal Register notice at 71 FR 38147
(July 5, 2006) or the EPA Web site at
https://www.epa.gov/epahome/dockets.htm
for current information on docket operations,
locations and telephone numbers. The
Docket Center’s mailing address for U.S. mail
and the procedure for submitting comments
to www.regulations.gov are not affected by
the flooding and will remain the same.
Submit your comments, identified by
Docket ID No. EPA-HQ-ORD 2004–0002
by one of the following methods:
• https://www.regulations.gov: Follow
the on-line instructions for submitting
comments.
• E-mail: ORD.Docket@epa.gov.
• Mail: Office of Environmental
Information (OEI) Docket (Mail Code:
2822T), U.S. Environmental Protection
Agency, 1200 Pennsylvania Ave., NW.,
Washington, DC 20460. The phone
number is (202) 566–1752.
• Hand Delivery: The OEI Docket is
located in the EPA Headquarters Docket
Center, EPA West Building, 1301
Constitution Ave., NW., Washington,
DC. The EPA Docket Center Public
Reading Room is open from 8:30 a.m. to
4:30 p.m., Monday through Friday,
excluding legal holidays. The telephone
E:\FR\FM\12OCN1.SGM
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Federal Register / Vol. 71, No. 197 / Thursday, October 12, 2006 / Notices
number for the Public Reading Room is
(202) 566–1744. Such deliveries are
only accepted during the docket’s
normal hours of operation, and special
arrangements should be made for
deliveries of boxed information.
If you provide comments by mail or
hand delivery, please submit one
unbound original with pages numbered
consecutively, and three copies of the
comments. For attachments, provide an
index, number pages consecutively with
the comments, and submit an unbound
original and three copies.
Instructions: Direct your comments to
Docket ID No. EPA–HQ–ORD–2004–
0002. EPA’s policy is that all comments
received will be included in the public
docket without change and may be
made available online at https://
www.regulations.gov, including any
personal information provided, unless
the comment includes information
claimed to be Confidential Business
Information (CBI) or other information
whose disclosure is restricted by statute.
Do not submit information that you
consider to be CBI or otherwise
protected through https://
www.regulations.gov or e-mail. The
https://www.regulations.gov Web site is
an ‘‘anonymous access’’ system, which
means EPA will not know your identity
or contact information unless you
provide it in the body of your comment.
If you send an e-mail comment directly
to EPA without going through https://
www.regulations.gov, your e-mail
address will be automatically captured
and included as part of the comment
that is placed in the public docket and
made available on the Internet. If you
submit an electronic comment, EPA
recommends that you include your
name and other contact information in
the body of your comment and with any
disk or CD–ROM you submit. If EPA
cannot read your comment due to
technical difficulties and cannot contact
you for clarification, EPA may not be
able to consider your comment.
Electronic files should avoid the use of
special characters, any form of
encryption, and be free of any defects or
viruses. For additional information
about EPA’s public docket visit the EPA
Docket Center homepage at https://
www.epa.gov/epahome/dockets.htm.
Docket: All documents in the docket
are listed in the https://
www.regulations.gov index. Although
listed in the index, some information is
not publicly available, e.g., CBI or other
information whose disclosure is
restricted by statute. Certain other
material, such as copyrighted material,
will be publicly available only in hard
copy. Publicly available docket
materials are available either
VerDate Aug<31>2005
16:21 Oct 11, 2006
Jkt 211001
electronically in https://
www.regulations.gov or in hard copy at
the OEI Docket in the EPA Headquarters
Docket Center.
Dated: October 5, 2006.
Peter W. Preuss,
Director, National Center for Environmental
Assessment.
[FR Doc. E6–16925 Filed 10–11–06; 8:45 am]
BILLING CODE 6560–50–P
ENVIRONMENTAL PROTECTION
AGENCY
[EPA–HQ–OPPT–2004–0128; FRL–8095–1]
National Advisory Committee for Acute
Exposure Guideline Levels (AEGLs) for
Hazardous Substances; Proposed
AEGL Values; Notice of Availability
Environmental Protection
Agency (EPA).
ACTION: Notice.
AGENCY:
SUMMARY: The National Advisory
Committee for Acute Exposure
Guideline Levels for Hazardous
Substances (NAC/AEGL Committee) is
developing AEGLs on an ongoing basis
to provide Federal, State, and local
agencies with information on short-term
exposures to hazardous chemicals. This
notice provides a list of 46 proposed
AEGL chemicals that are available for
public review and comment. Comments
are welcome on both the AEGL values
and the technical support documents
placed in the docket.
DATES: Comments must be received on
or before November 13, 2006.
ADDRESSES: Submit your comments,
identified by docket identification (ID)
number EPA–HQ–OPPT–2004–0128, by
one of the following methods:
• Federal eRulemaking Portal: https://
www.regulations.gov. Follow the on-line
instructions for submitting comments.
• Mail: Document Control Office
(7407M), Office of Pollution Prevention
and Toxics (OPPT), Environmental
Protection Agency, 1200 Pennsylvania
Ave., NW., Washington, DC 20460–
0001.
• Hand Delivery: OPPT Document
Control Office (DCO), EPA East, Rm.
6428, 1201 Constitution Ave., NW.,
Washington, DC. Attention: Docket ID
Number EPA–HQ–OPPT–2004–0128.
The DCO is open from 8 a.m. to 4 p.m.,
Monday through Friday, excluding legal
holidays. The telephone number for the
DCO is (202) 564–8930. Such deliveries
are only accepted during the DCO’s
normal hours of operation, and special
arrangements should be made for
deliveries of boxed information.
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60141
Instructions: Direct your comments to
docket ID number EPA–HQ–OPPT–
2004–0128. EPA’s policy is that all
comments received will be included in
the docket without change and may be
made available on-line at https://
www.regulations.gov, including any
personal information provided, unless
the comment includes information
claimed to be Confidential Business
Information (CBI) or other information
whose disclosure is restricted by statute.
Do not submit information that you
consider to be CBI or otherwise
protected through regulations.gov or email. The regulations.gov Web site is an
‘‘anonymous access’’ system, which
means EPA will not know your identity
or contact information unless you
provide it in the body of your comment.
If you send an e-mail comment directly
to EPA without going through
regulations.gov, your e-mail address
will be automatically captured and
included as part of the comment that is
placed in the docket and made available
on the Internet. If you submit an
electronic comment, EPA recommends
that you include your name and other
contact information in the body of your
comment and with any disk or CD-ROM
you submit. If EPA cannot read your
comment due to technical difficulties
and cannot contact you for clarification,
EPA may not be able to consider your
comment. Electronic files should avoid
the use of special characters, any form
of encryption, and be free of any defects
or viruses. For additional information
about EPA’s public docket, visit the EPA
Docket Center homepage at https://
www.epa.gov/epahome/dockets.htm.
Docket: All documents in the docket
are listed in the regulations.gov index.
Although listed in the index, some
information is not publicly available,
e.g., CBI or other information whose
disclosure is restricted by statute.
Certain other material, such as
copyrighted material, will be publicly
available only in hard copy. Publicly
available docket materials are available
electronically at https://
www.regulations.gov, or, if only
available in hard copy, at the OPPT
Docket, EPA Docket Center (EPA/DC).
The EPA/DC suffered structural damage
due to flooding in June 2006. Although
the EPA/DC is continuing operations,
there will be temporary changes to the
EPA/DC during the clean-up. The EPA/
DC Public Reading Room, which was
temporarily closed due to flooding, has
been relocated in the EPA Headquarters
Library, Infoterra Room (Room Number
3334) in EPA West, located at 1301
Constitution Ave., NW., Washington,
DC. The EPA/DC Public Reading Room
E:\FR\FM\12OCN1.SGM
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]]>Agencies
[Federal Register Volume 71, Number 197 (Thursday, October 12, 2006)]
[Notices]
[Pages 60139-60141]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E6-16925]
=======================================================================
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
[FRL-8230-6; Docket ID No. EPA-HQ-ORD-2004-0002]
Draft Toxicological Review of Dichlorobenzenes: In Support of
Summary Information on the Integrated Risk Information System (IRIS)
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of Extension of Public Comment Period, Rescheduled
External Peer Review Panel Meeting, and Meeting Format Change.
-----------------------------------------------------------------------
SUMMARY: The EPA is extending the public comment period and
rescheduling an external peer review panel meeting to review selected
sections of the EPA National Center for Environmental Assessment (NCEA)
final draft document titled, ``Toxicological Review of
Dichlorobenzenes: In Support of Summary Information on the Integrated
Risk Information System (IRIS)'' (EPA/635/R-03/015), regarding the
inhalation reference concentration (RfC) and inhalation cancer
assessment for 1,4-dichlorobenzene. The EPA is also changing the format
of this external peer review meeting to include both a teleconference
and an in-person panel meeting.
On July 11, 2006, EPA published a Federal Register notice (71 FR
39113) announcing a comment period that ended August 9 and an external
peer review panel meeting (by teleconference) that was scheduled for
August 16. On August 11, 2006, EPA published a second Federal Register
notice announcing an extension of the public comment period to October
10 and a rescheduling of the external peer review meeting to October
30. EPA is extending the public comment period to October 17, 2006,
rescheduling the external peer review meeting to November 3, 2006, and
changing the format to include both a face-to-face meeting and a
teleconference option for participation. This extended public comment
period and change in format for the external peer review are in
response to requests from the public.
The public comment period and the external peer review meeting are
separate processes that provide opportunities for all interested
parties to comment on the document. In addition to consideration by
EPA, all public comments submitted in accordance with this notice will
also be forwarded to EPA's contractor, the Oak Ridge Institute for
Science and Education (ORISE), for consideration by the external peer
review panel prior to the meeting.
As previously stated in 71 FR 39113 and 71 FR 46220, EPA is
releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality
guidelines. This document has not been formally disseminated by EPA. It
does not represent and should not be construed to represent any Agency
policy or determination.
ORISE invites the public to register to attend this peer review
panel meeting as observers, either in person or by telephone. In
addition, ORISE invites the public to give brief oral comments at the
meeting regarding the draft document under review. The draft document
and EPA's peer review charge are available via the Internet on NCEA's
home page under the Recent Additions menu at https://www.epa.gov/ncea.
When finalizing this draft report, EPA will consider ORISE's report of
the comments and recommendations from the external peer reviewers and
any public comments that EPA receives in accordance with this notice.
DATES: The period for submission of comments on the final draft
document will end on October 17, 2006. Technical
[[Page 60140]]
comments should be in writing and must be received by EPA by October
17, 2006. Comments submitted to the EPA by October 17, 2006, will be
provided to the external peer review panel prior to the panel review
meeting. The peer review will be on November 3, 2006, and will begin at
9 a.m. and end approximately at 1 p.m., eastern time.
ADDRESSES: The external peer review panel meeting will be held at the
American Geophysical Union, 2000 Florida Avenue, NW., Washington, DC
20009-1277. Under an Interagency Agreement between EPA and the
Department of Energy, the Oak Ridge Institute of Science and Education
(ORISE) is organizing, convening, and conducting the peer review panel
meeting. To attend the meeting, register by October 17, 2006, by
calling ORISE at (865) 576-2922, sending a facsimile to (865) 241-3168,
or sending an e-mail to Margaret Lyday at lydaym@orau.gov. Interested
parties may also register via the Internet at https://www.orau.gov/
dichlorobenzene. You must register by October 17, 2006, if you wish to
provide brief oral comments or if you plan to use the teleconference
option at the peer review panel meeting.
The draft ``Toxicological Review of Dichlorobenzenes: In Support of
Summary Information on the Integrated Risk Information System (IRIS)''
(EPA/635/R-03/015) is available primarily via the Internet on NCEA's
home page under the Recent Additions menu at https://www.epa.gov/ncea. A
limited number of paper copies are available by contacting the IRIS
Hotline at (202) 566-1676, (202) 566-1749 (facsimile), or
hotline.iris@epa.gov. If you are requesting a paper copy, please
provide your name, mailing address, the document title, and the EPA
number of the requested publication. Copies are not available from
ORISE.
Copies of the study by Aiso et al. (2005), referenced in the
SUPPLEMENTARY INFORMATION section of this notice, are available from
the IRIS Hotline in paper or electronic format or via the docket at
https://www.regulations.gov. If you are requesting a copy from the IRIS
Hotline, please provide your name, mailing address or e-mail address,
and document citation: Aiso et al. (2005) Carcinogenicity and chronic
toxicity in mice and rats exposed by inhalation to parA-dichlorobenzene
for two years. J Vet Med Sci 67(10):1019-1029. EPA is providing this
study in the interest of transparency. EPA is not endorsing or
supporting the study or its findings.
Technical comments may be submitted electronically via https://
www.regulations.gov, by mail, by facsimile, or by hand delivery/
courier. Please follow the detailed instructions provided in the
SUPPLEMENTARY INFORMATION section of this notice.
FOR FURTHER INFORMATION CONTACT: Questions regarding registration and
logistics for the external peer review panel meeting and teleconference
should be directed to Margaret Lyday, ORISE, P.O. Box 117, MS 17, Oak
Ridge, TN 37831-0117, at (865) 576-2922, (865) 241-3168 (facsimile), or
lydaym@orau.gov (e-mail).
If you have questions about the document, contact Audrey Galizia,
Chemical Manager, National Center for Environmental Assessment;
telephone: (732) 906-6887; facsimile: (732) 452-6429; e-mail:
galizia.audrey@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Information About the Document
IRIS is a database that contains Agency scientific positions on
potential adverse human health effects that may result from chronic (or
lifetime) exposure to specific chemical substances found in the
environment. The database (available on the Internet at https://
www.epa.gov/iris) contains qualitative and quantitative health effects
information for more than 500 chemical substances that may be used to
support the first two steps (hazard identification and dose-response
evaluation) of the risk assessment process. When supported by available
data, the database can be used as a resource for oral reference doses
(RfDs) and inhalation reference concentrations (RfCs) for chronic
health effects, and oral slope factors and inhalation unit risks for
carcinogenic effects. Combined with specific exposure information,
government and private entities use IRIS to help characterize public
health risks of chemical substances in a site-specific situation and
thereby support risk management decisions designed to protect public
health.
1,4-Dichlorobenzene is widely used as a space deodorant for toilets
and refuse containers, as a moth repellent in moth balls or crystals,
and in other pesticide applications. The current IRIS assessment for
1,4-dichlorobenzene was placed on the database in 1994 and contains an
inhalation RfC. A reassessment of the potential health effects of
dichlorobenzenes has been undertaken. The draft assessment for
dichlorobenzenes (including the 1,2-, 1,3-, and 1,4-isomers) was
subject to an external peer review and 30-day public comment period in
February 2004 (69 FR 4514, January 30, 2004). The scope of the current
external peer review and public comment is limited to the analyses
based on a chronic inhalation bioassay of 1,4-dichlorobenzene published
in the peer-reviewed literature (Aiso et al., 2005. J Vet Med Sci
67(10):1019-29) that was not included in the February 2004 external
peer review draft. This study was identified originally as an
unpublished study report by the Japan Bioassay Research Center (JBRC,
1995). Data from Aiso et al. (2005) were used subsequently in the
quantitative dose-response assessments for the 1,4-dichlorobenzene RfC
and inhalation cancer assessment.
II. Panel Meeting Information
Members of the public may attend the panel meeting as observers,
and there will be a limited time for comments from the public. To make
oral comments at the commencement of the peer review meeting, you must
pre-register with ORISE indicating your intent to do so. Space is
limited, and reservations will be accepted on a first-come, first-
served basis.
III. How to Submit Technical Comments to the Docket at https://
www.regulations.gov
Note: The EPA Docket Center suffered damage due to flooding
during the last week of June 2006. The Docket Center is continuing
to operate. However, during the cleanup, there will be temporary
changes to Docket Center telephone numbers, addresses, and hours of
operation for people who wish to make hand deliveries or visit the
Public Reading Room to view documents. Consult EPA's Federal
Register notice at 71 FR 38147 (July 5, 2006) or the EPA Web site at
https://www.epa.gov/epahome/dockets.htm for current information on
docket operations, locations and telephone numbers. The Docket
Center's mailing address for U.S. mail and the procedure for
submitting comments to www.regulations.gov are not affected by the
flooding and will remain the same.
Submit your comments, identified by Docket ID No. EPA-HQ-ORD 2004-
0002 by one of the following methods:
https://www.regulations.gov: Follow the on-line
instructions for submitting comments.
E-mail: ORD.Docket@epa.gov.
Mail: Office of Environmental Information (OEI) Docket
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is (202)
566-1752.
Hand Delivery: The OEI Docket is located in the EPA
Headquarters Docket Center, EPA West Building, 1301 Constitution Ave.,
NW., Washington, DC. The EPA Docket Center Public Reading Room is open
from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal
holidays. The telephone
[[Page 60141]]
number for the Public Reading Room is (202) 566-1744. Such deliveries
are only accepted during the docket's normal hours of operation, and
special arrangements should be made for deliveries of boxed
information.
If you provide comments by mail or hand delivery, please submit one
unbound original with pages numbered consecutively, and three copies of
the comments. For attachments, provide an index, number pages
consecutively with the comments, and submit an unbound original and
three copies.
Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2004-0002. EPA's policy is that all comments received will be included
in the public docket without change and may be made available online at
https://www.regulations.gov, including any personal information
provided, unless the comment includes information claimed to be
Confidential Business Information (CBI) or other information whose
disclosure is restricted by statute. Do not submit information that you
consider to be CBI or otherwise protected through https://
www.regulations.gov or e-mail. The https://www.regulations.gov Web site
is an ``anonymous access'' system, which means EPA will not know your
identity or contact information unless you provide it in the body of
your comment. If you send an e-mail comment directly to EPA without
going through https://www.regulations.gov, your e-mail address will be
automatically captured and included as part of the comment that is
placed in the public docket and made available on the Internet. If you
submit an electronic comment, EPA recommends that you include your name
and other contact information in the body of your comment and with any
disk or CD-ROM you submit. If EPA cannot read your comment due to
technical difficulties and cannot contact you for clarification, EPA
may not be able to consider your comment. Electronic files should avoid
the use of special characters, any form of encryption, and be free of
any defects or viruses. For additional information about EPA's public
docket visit the EPA Docket Center homepage at https://www.epa.gov/
epahome/dockets.htm.
Docket: All documents in the docket are listed in the https://
www.regulations.gov index. Although listed in the index, some
information is not publicly available, e.g., CBI or other information
whose disclosure is restricted by statute. Certain other material, such
as copyrighted material, will be publicly available only in hard copy.
Publicly available docket materials are available either electronically
in https://www.regulations.gov or in hard copy at the OEI Docket in the
EPA Headquarters Docket Center.
Dated: October 5, 2006.
Peter W. Preuss,
Director, National Center for Environmental Assessment.
[FR Doc. E6-16925 Filed 10-11-06; 8:45 am]
BILLING CODE 6560-50-P
