Evaluation of the Carcinogenicity of Ethylene Oxide, 60143-60144 [E6-16921]
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Federal Register / Vol. 71, No. 197 / Thursday, October 12, 2006 / Notices
Chemical name
CAS No.
List of Subjects
Environmental protection, Acute
Exposure Guideline Levels (AEGLs),
Hazardous substances.
Chlorine pentafluoride
13637–63–3
Chloroacetaldehye
107–20–0
Chloroacetone
78–95–5
Chloroacetonitrile
107–14–2
Chloroacetyl chloride
79–04–9
Cumene
98–82–8
Dichloroacetyl chloride
79–36–7
Dimethyl sulfate
77–78–1
Disulfur dichloride
10025–67–9
Ethyl acrylate
140–88–5
Evaluation of the Carcinogenicity of
Ethylene Oxide
Ethyl mercaptan
75–08–1
AGENCY:
Formaldehyde
50–00–0
Hexane
110–54–3
Hydrogen bromide
10035–10–6
Hydrogen iodide
10034–85–2
Hydrogen selenide
7783–07–5
Isobutyronitrile
78–82–0
Lewisite L-1
541–25–3
Lewisite L-2
40334–69–8
Lewisite L-3
40334–70–1
Malononitrile
109–77–3
Methacrylic acid
79–41–4
Methacrylonitrile
126–98–7
Methyl bromide
74–83–9
Methyl chloride
74–87–3
Methyl methacrylate
80–62–6
Methylene chloride
75–09–2
Oleum
8014–95–7
Piperidine
110–89–4
Propane
74–98–6
Propionaldehyde
123–38–6
Proprionitrile
107–12–0
Styrene
110–42–5
Sulfur trioxide
7446–11–9
Sulfuric acid
7664–93–9
Titanium tetrachloride
7550–45–0
Vinyl chloride
75–01–4
Dated: October 5, 2006.
Charles M. Auer,
Director, Office of Pollution Prevention and
Toxics.
[FR Doc. E6–16908 Filed 10–11–06; 8:45 am]
rwilkins on PROD1PC63 with NOTICES
BILLING CODE 6560–50–S
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Jkt 211001
ENVIRONMENTAL PROTECTION
AGENCY
[FRL–8230–7; Docket ID No. EPA–HQ–ORD–
2006–0756]
Environmental Protection
Agency (EPA).
ACTION: Notice of Extension of Public
Comment Period.
SUMMARY: EPA is announcing an
extension of the public comment period
for the draft document titled,
‘‘Evaluation of the Carcinogenicity of
Ethylene Oxide’’ (EPA/635/R–06/003).
The document was prepared by the
National Center for Environmental
Assessment within EPA’s Office of
Research and Development. On
September 22, EPA published a Federal
Register notice (71 FR 55470)
announcing a 30-day comment period
that ends October 23, 2007. EPA is
extending the public comment period to
December 8, 2006, in response to
requests.
As previously stated in 71 FR 55470,
EPA is releasing this draft document
solely for the purpose of seeking public
comment and for review by the EPA
Science Advisory Board (SAB) via a
meeting to be held at a later date (time
and place to be specified in a separate
Federal Register notice). This document
has not been formally disseminated by
EPA. It does not determination. EPA
will consider any public comments
submitted in accordance with this
notice when revising the document.
DATES: The public comment period
began September 22, 2006, and ends
December 8, 2006. Technical comments
should be in writing and must be
received by EPA by December 8, 2006.
ADDRESSES: The draft ‘‘Evaluation of the
Carcinogenicity of Ethylene Oxide’’ is
available primarily via the Internet on
the National Center for Environmental
Assessment’s home page under the
Recent Additions and the Data and
Publications menus at https://
www.epa.gov/ncea. A limited number of
paper copies are available from the
PO 00000
Frm 00037
Fmt 4703
Sfmt 4703
60143
Technical Information Staff, NCEA–W;
telephone: 202–564–3261; facsimile:
202–565–0050. If you are requesting a
paper copy, please provide your name,
your mailing address, and the document
title, ‘‘Evaluation of the Carcinogenicity
of Ethylene Oxide’’.
Comments may be submitted
electronically via www.regulations.gov,
by mail, by facsimile, or by hand
delivery/courier. Please follow the
detailed instructions provided in the
SUPPLEMENTARY INFORMATION section of
this notice.
FOR FURTHER INFORMATION CONTACT: For
information on the public comment
period, contact the Office of
Environmental Information Docket;
telephone: 202–566–1752; facsimile:
202–566–1753; or e-mail:
ORD.Docket@epa.gov.
For technical information, contact
Henry D. Kahn, D.Sc., NCEA; telephone:
202–564–3269; facsimile: 202–565–
0079; or e-mail: kahn.henry@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Information About the Project/
Document
Ethylene oxide (EtO) is a gas at room
temperature. It is manufactured from
ethylene and used primarily as a
chemical intermediate in the
manufacture of ethylene glycol. It is also
used as a sterilizing agent for medical
equipment and as a fumigating agent for
spices. The largest sources of human
exposure are in occupations involving
contact with the gas in production
facilities and in hospitals that sterilize
medical equipment. EtO can also be
inhaled by residents living near
production or sterilizing/fumigating
facilities.
This draft assessment document
characterizes the potential for a
carcinogenic health hazard from human
inhalation exposure to EtO. This is
accomplished by a weight-of-evidence
evaluation as to how likely EtO is to be
a human carcinogen, as well as an
evaluation of related dose-response
information which leads to the
development of lifetime cancer risk
estimates per unit of exposure. This
assessment, when finalized, will be
posted to EPA’s Integrated Risk
Information System (IRIS) database. The
document was prepared by EPA’s
National Center for Environmental
Assessment (NCEA). EPA last published
a health assessment of the potential
carcinogenicity of EtO in 1985.
The current assessment reviews the
more recently developed database on
the carcinogenicity of EtO, pertinent
data from the 1985 assessment, and
several reviews and assessments issued
E:\FR\FM\12OCN1.SGM
12OCN1
60144
Federal Register / Vol. 71, No. 197 / Thursday, October 12, 2006 / Notices
by other organizations (IARC, 1994;
Health Canada, 2001; CalEPA, 1999;
EOIC, 2001).
II. How to Submit Technical Comments
to the Docket at www.regulations.gov
rwilkins on PROD1PC63 with NOTICES
Note: The EPA Docket Center suffered
damage due to flooding during the last week
of June 2006. The Docket Center is
continuing to operate. However, during the
cleanup, there will be temporary changes to
Docket Center telephone numbers, addresses,
and hours of operation for people who wish
to make hand deliveries or visit the Public
Reading Room to view documents. Consult
EPA’s Federal Register notice at 71 FR 38147
(July 5, 2006) or the EPA Web site at https://
www.epa.gov/epahome/dockets.htm for
current information on docket operations,
locations and telephone numbers. The
Docket Center’s mailing address for U.S. mail
and the procedure for submitting comments
to www.regulations.gov are not affected by
the flooding and will remain the same.
Submit your comments, identified by
Docket ID No. EPA–HQ–ORD 2006–
0756 by one of the following methods:
• www.regulations.gov: Follow the
on-line instructions for submitting
comments.
• E-mail: ORD.Docket@epa.gov.
• Fax: 202–566–1753
• Mail: Office of Environmental
Information (OEI) Docket (Mail Code:
2822T), U.S. Environmental Protection
Agency, 1200 Pennsylvania Ave., NW.,
Washington, DC 20460. The phone
number is 202–566–1752.
• Hand Delivery: The OEI Docket is
located in the EPA Headquarters Docket
Center, EPA West Building, 1301
Constitution Ave., NW., Washington,
DC. The EPA Docket Center Public
Reading Room is open from 8:30 a.m. to
4:30 p.m., Monday through Friday,
excluding legal holidays. The telephone
number for the Public Reading Room is
202–566–1744. Such deliveries are only
accepted during the docket’s normal
hours of operation, and special
arrangements should be made for
deliveries of boxed information.
If you submit comments by mail or
hand delivery, please submit one
unbound original with pages numbered
consecutively, and three copies of the
comments. For attachments, provide an
index, number pages consecutively with
the comments, and submit an unbound
original and three copies.
Instructions: Direct your comments to
Docket ID No. EPA–HQ–ORD–2006–
0756. Please ensure that your comments
are submitted within the specified
comment period. Comments received
after the closing date will be marked
‘‘late,’’ and may only be considered if
time permits. It is EPA’s policy to
include all comments it receives in the
public docket without change and to
VerDate Aug<31>2005
16:21 Oct 11, 2006
Jkt 211001
make the comments available online at
www.regulations.gov, including any
personal information provided, unless a
comment includes information claimed
to be Confidential Business Information
(CBI) or other information whose
disclosure is restricted by statute. Do
not submit information that you
consider to be CBI or otherwise
protected through www.regulations.gov
or e-mail. The www.regulations.gov Web
site is an ‘‘anonymous access’’ system,
which means EPA will not know your
identity or contact information unless
you provide it in the body of your
comment. If you send an e-mail
comment directly to EPA without going
through www.regulations.gov, your email address will be automatically
captured and included as part of the
comment that is placed in the public
docket and made available on the
Internet. If you submit an electronic
comment, EPA recommends that you
include your name and other contact
information in the body of your
comment and with any disk or CD–ROM
you submit. If EPA cannot read your
comment due to technical difficulties
and cannot contact you for clarification,
EPA may not be able to consider your
comment. Electronic files should avoid
the use of special characters, any form
of encryption, and be free of any defects
or viruses. For additional information
about EPA’s public docket visit the EPA
Docket Center homepage at https://
www.epa.gov/epahome/dockets.htm.
Docket: Documents in the docket are
listed in the www.regulations.gov index.
Although listed in the index, some
information is not publicly available,
e.g., CBI or other information whose
disclosure is restricted by statute.
Certain other materials, such as
copyrighted material, are publicly
available only in hard copy. Publicly
available docket materials are available
either electronically in
www.regulations.gov or in hard copy at
the OEI Docket in the EPA Headquarters
Docket Center.
Dated: October 4, 2006.
Peter W. Preuss,
Director, National Center for Environmental
Assessment.
[FR Doc. E6–16921 Filed 10–11–06; 8:45 am]
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ENVIRONMENTAL PROTECTION
AGENCY
[FRL–8230–3]
Compliance Assistance Centers;
Request for Suggestions on
Candidates for Compliance Assistance
Center Development
Environmental Protection
Agency.
ACTION: Solicitation for suggestions.
AGENCY:
SUMMARY: In partnership with industry,
academic institutions, environmental
groups, and other agencies, the
Environmental Protection Agency (EPA)
supports fourteen Compliance
Assistance Centers (Centers) to help
small- and medium-size businesses and
local governments better understand
and comply with environmental
regulations. These Centers provide easy
to understand compliance information
targeted to specific sectors, geographic
and environmental topics: agriculture;
automotive service and repair;
automotive recycling, chemical
manufacturers; construction; Federal
facilities; health care; local
governments, metal finishing; paints
and coatings; printed wiring board
manufacturers; printers; transportation;
and the U.S. / Mexico / Canada border
environmental issues. Additionally,
funding has recently been awarded to
initiate the development of a Center for
the education sector. All Centers can be
accessed at https://
www.assistancecneters.net. EPA would
like to expand the Center program to
support other sectors, geographical areas
or topical issues.
To support new Center development,
EPA has funded the National Center for
Manufacturing Sciences (NCMS) to
develop, operate and maintain the
Compliance Assistance Center Platform
(Platform) from which new Centers will
be ‘‘launched.’’ The Platform includes a
suite of comprehensive Web-based tools
necessary new Centers. States, industry,
and compliance assistance providers
can work with NCMS to establish
Centers that will help the regulated
community better understand and more
efficiently comply with environmental
requirements. The Centers for the metal
finishing, printed wiring board
manufacturing, paints and coatings,
construction sector, automotive
recycling sector, health care and U.S. /
Mexico / Cananda border environmental
issues have been developed in
partnership with NCMS and the
Platform. Visit https://www.envcap.org to
access Platform resources.
EPA is exploring new sector,
geographical, or topical candidates for
E:\FR\FM\12OCN1.SGM
12OCN1
]]>Agencies
[Federal Register Volume 71, Number 197 (Thursday, October 12, 2006)]
[Notices]
[Pages 60143-60144]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E6-16921]
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
[FRL-8230-7; Docket ID No. EPA-HQ-ORD-2006-0756]
Evaluation of the Carcinogenicity of Ethylene Oxide
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of Extension of Public Comment Period.
-----------------------------------------------------------------------
SUMMARY: EPA is announcing an extension of the public comment period
for the draft document titled, ``Evaluation of the Carcinogenicity of
Ethylene Oxide'' (EPA/635/R-06/003). The document was prepared by the
National Center for Environmental Assessment within EPA's Office of
Research and Development. On September 22, EPA published a Federal
Register notice (71 FR 55470) announcing a 30-day comment period that
ends October 23, 2007. EPA is extending the public comment period to
December 8, 2006, in response to requests.
As previously stated in 71 FR 55470, EPA is releasing this draft
document solely for the purpose of seeking public comment and for
review by the EPA Science Advisory Board (SAB) via a meeting to be held
at a later date (time and place to be specified in a separate Federal
Register notice). This document has not been formally disseminated by
EPA. It does not determination. EPA will consider any public comments
submitted in accordance with this notice when revising the document.
DATES: The public comment period began September 22, 2006, and ends
December 8, 2006. Technical comments should be in writing and must be
received by EPA by December 8, 2006.
ADDRESSES: The draft ``Evaluation of the Carcinogenicity of Ethylene
Oxide'' is available primarily via the Internet on the National Center
for Environmental Assessment's home page under the Recent Additions and
the Data and Publications menus at https://www.epa.gov/ncea. A limited
number of paper copies are available from the Technical Information
Staff, NCEA-W; telephone: 202-564-3261; facsimile: 202-565-0050. If you
are requesting a paper copy, please provide your name, your mailing
address, and the document title, ``Evaluation of the Carcinogenicity of
Ethylene Oxide''.
Comments may be submitted electronically via www.regulations.gov,
by mail, by facsimile, or by hand delivery/courier. Please follow the
detailed instructions provided in the SUPPLEMENTARY INFORMATION section
of this notice.
FOR FURTHER INFORMATION CONTACT: For information on the public comment
period, contact the Office of Environmental Information Docket;
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail:
ORD.Docket@epa.gov.
For technical information, contact Henry D. Kahn, D.Sc., NCEA;
telephone: 202-564-3269; facsimile: 202-565-0079; or e-mail:
kahn.henry@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Information About the Project/Document
Ethylene oxide (EtO) is a gas at room temperature. It is
manufactured from ethylene and used primarily as a chemical
intermediate in the manufacture of ethylene glycol. It is also used as
a sterilizing agent for medical equipment and as a fumigating agent for
spices. The largest sources of human exposure are in occupations
involving contact with the gas in production facilities and in
hospitals that sterilize medical equipment. EtO can also be inhaled by
residents living near production or sterilizing/fumigating facilities.
This draft assessment document characterizes the potential for a
carcinogenic health hazard from human inhalation exposure to EtO. This
is accomplished by a weight-of-evidence evaluation as to how likely EtO
is to be a human carcinogen, as well as an evaluation of related dose-
response information which leads to the development of lifetime cancer
risk estimates per unit of exposure. This assessment, when finalized,
will be posted to EPA's Integrated Risk Information System (IRIS)
database. The document was prepared by EPA's National Center for
Environmental Assessment (NCEA). EPA last published a health assessment
of the potential carcinogenicity of EtO in 1985.
The current assessment reviews the more recently developed database
on the carcinogenicity of EtO, pertinent data from the 1985 assessment,
and several reviews and assessments issued
[[Page 60144]]
by other organizations (IARC, 1994; Health Canada, 2001; CalEPA, 1999;
EOIC, 2001).
II. How to Submit Technical Comments to the Docket at
www.regulations.gov
Note: The EPA Docket Center suffered damage due to flooding
during the last week of June 2006. The Docket Center is continuing
to operate. However, during the cleanup, there will be temporary
changes to Docket Center telephone numbers, addresses, and hours of
operation for people who wish to make hand deliveries or visit the
Public Reading Room to view documents. Consult EPA's Federal
Register notice at 71 FR 38147 (July 5, 2006) or the EPA Web site at
https://www.epa.gov/epahome/dockets.htm for current information on
docket operations, locations and telephone numbers. The Docket
Center's mailing address for U.S. mail and the procedure for
submitting comments to www.regulations.gov are not affected by the
flooding and will remain the same.
Submit your comments, identified by Docket ID No. EPA-HQ-ORD 2006-
0756 by one of the following methods:
www.regulations.gov: Follow the on-line instructions for
submitting comments.
E-mail: ORD.Docket@epa.gov.
Fax: 202-566-1753
Mail: Office of Environmental Information (OEI) Docket
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
Hand Delivery: The OEI Docket is located in the EPA
Headquarters Docket Center, EPA West Building, 1301 Constitution Ave.,
NW., Washington, DC. The EPA Docket Center Public Reading Room is open
from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal
holidays. The telephone number for the Public Reading Room is 202-566-
1744. Such deliveries are only accepted during the docket's normal
hours of operation, and special arrangements should be made for
deliveries of boxed information.
If you submit comments by mail or hand delivery, please submit one
unbound original with pages numbered consecutively, and three copies of
the comments. For attachments, provide an index, number pages
consecutively with the comments, and submit an unbound original and
three copies.
Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2006-0756. Please ensure that your comments are submitted within the
specified comment period. Comments received after the closing date will
be marked ``late,'' and may only be considered if time permits. It is
EPA's policy to include all comments it receives in the public docket
without change and to make the comments available online at
www.regulations.gov, including any personal information provided,
unless a comment includes information claimed to be Confidential
Business Information (CBI) or other information whose disclosure is
restricted by statute. Do not submit information that you consider to
be CBI or otherwise protected through www.regulations.gov or e-mail.
The www.regulations.gov Web site is an ``anonymous access'' system,
which means EPA will not know your identity or contact information
unless you provide it in the body of your comment. If you send an e-
mail comment directly to EPA without going through www.regulations.gov,
your e-mail address will be automatically captured and included as part
of the comment that is placed in the public docket and made available
on the Internet. If you submit an electronic comment, EPA recommends
that you include your name and other contact information in the body of
your comment and with any disk or CD-ROM you submit. If EPA cannot read
your comment due to technical difficulties and cannot contact you for
clarification, EPA may not be able to consider your comment. Electronic
files should avoid the use of special characters, any form of
encryption, and be free of any defects or viruses. For additional
information about EPA's public docket visit the EPA Docket Center
homepage at https://www.epa.gov/epahome/dockets.htm.
Docket: Documents in the docket are listed in the
www.regulations.gov index. Although listed in the index, some
information is not publicly available, e.g., CBI or other information
whose disclosure is restricted by statute. Certain other materials,
such as copyrighted material, are publicly available only in hard copy.
Publicly available docket materials are available either electronically
in www.regulations.gov or in hard copy at the OEI Docket in the EPA
Headquarters Docket Center.
Dated: October 4, 2006.
Peter W. Preuss,
Director, National Center for Environmental Assessment.
[FR Doc. E6-16921 Filed 10-11-06; 8:45 am]
BILLING CODE 6560-50-P
