The National Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control and Prevention (CDC) Announcement Opportunity for Businesses To Partner With National Institute for Occupational Safety and Health (NIOSH) on a Research Project To Evaluate the Reusability of Disposable Filtering Facepiece Respirators (FFR) Used for Protection Against Infectious Aerosols, 56151-56152 [E6-15706]
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56151
Federal Register / Vol. 71, No. 186 / Tuesday, September 26, 2006 / Notices
No. of
respondents
Respondents
Adult—cases and controls .........................................................................................
Dated: September 20, 2006.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for
Disease Control and Prevention.
[FR Doc. E6–15703 Filed 9–25–06; 8:45 am]
BILLING CODE 4163–18–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Disease Control and
Prevention
The National Institute for Occupational
Safety and Health (NIOSH) of the
Centers for Disease Control and
Prevention (CDC) Announcement
Opportunity for Businesses To Partner
With National Institute for
Occupational Safety and Health
(NIOSH) on a Research Project To
Evaluate the Reusability of Disposable
Filtering Facepiece Respirators (FFR)
Used for Protection Against Infectious
Aerosols
Authority: 29 U.S.C. Sections 651 et seq.
The National Institute for
Occupational Safety and Health
(NIOSH), Centers for Disease Control
and Prevention (CDC).
ACTION: Notice.
pwalker on PRODPC60 with NOTICES
AGENCY:
SUMMARY: The National Personal
Protective Technology Laboratory
(NPPTL), NIOSH, is conducting research
to determine the reusability of filtering
facepiece respirators (FFR) exposed to
infectious aerosols. One aim of this
research is to address whether NIOSHcertified FFR are suitable for reuse after
decontamination. NIOSH proposes to
study the effects of decontaminating a
diverse array of FFR including NIOSHcertified N95, P100, and N95 filtering
facepiece respirator/surgical mask. This
project will also study the survivability
of a simulant influenza virus on FFR.
NIOSH plans to include in the research
study some of the respirator models that
have been stockpiled by the U.S
government to be used in the event of
an influenza pandemic. NIOSH also
plans to include models that have head
straps versus those that do not have
head straps, as well as models with and
without exhalation valves.
Through this announcement, NIOSH
is seeking to identify FFR products or
prototypes that possess anti-viral or
other novel technologies that disinfect
or sterilize infectious aerosols (e.g.,
VerDate Aug<31>2005
21:03 Sep 25, 2006
Jkt 208001
434
viruses) as part of their materials of
construction. Program funding
constraints may limit the number of
candidate respirators that may be
included in the research program.
NIOSH will give consideration to the
incorporation of novel anti-viral
technologies into this research study
using the following hierarchy for
selection of candidate FFR products and
prototypes: (1) The FFR proposed for
consideration in this study are
commercially available and are
currently certified to meeting 42 CFR
part 84 requirements, (2) the FFR
proposed for consideration is in the
process of being certified by NIOSH to
meet 42 CFR part 84 requirements, (3)
the FFR proposed for consideration are
either a prototype or a commercially
available product that has not been
submitted to NIOSH for certification
and the manufacturer submitting the
letter of interest has received NIOSH
certification for other respiratory
protection products, and (4) the FFR
prototype contains a unique technology
for disinfecting or sterilizing infectious
aerosol particles trapped on the exterior
surface of the FFR and complements the
diversity of technologies already
considered in the research design.
Candidate companies will be
evaluated based on their capability to
achieve the identified criteria in
sufficient quantities for testing.
Candidates selected could be requested
to enter into a Cooperative Research and
Development Agreement (CRADA). This
announcement does not obligate NIOSH
to enter into a contractual agreement
with any respondents. NIOSH reserves
the right to establish a partnership based
on scientific analysis and capabilities
found by way of this announcement or
other searches, if determined to be in
the best interest of the government.
DATES: Submit letters of interest within
30 days after the date of publication of
this notice in the Federal Register.
ADDRESSES: Interested manufacturers
should submit a letter of interest with
information about their capabilities to:
NIOSH, National Personal Protection
Technology Laboratory, P.O. Box 18070,
626 Cochrans Mill Road, Attn: Jonathan
Szalajda, Pittsburgh, PA 15236, E-mail
address: zfx1@cdc.gov.
SUPPLEMENTARY INFORMATION: CDC
recommends the use of disposable N95,
N99, or N100 filtering facepiece
particulate respirators (FFR) as the
PO 00000
Frm 00052
Fmt 4703
Sfmt 4703
No. of responses
per respondent
1
Average burden
per response
1
minimum level of respiratory protection
against transmission of influenza virus.
During a respirator shortage, it is
important to consider whether a
previously worn FFR can be used again.
Reuse guidelines in the NIOSH Guide to
the Selection and Use of Particulate
Respirators Certified under 42 CFR 84
recommend reuse based on loading of
the filter and functioning of the
respirator. Hospital settings tend to have
relatively low concentrations of
particulates, but the potential for
infectious agents exists. Thus, reuse is
more dependent upon infection control
procedures than on respirator loading
considerations. Respirators exposed to
viruses are considered to be potentially
harmful because of the possibility for
the respirator to act as a fomite and the
potential for the viral particle to become
dislodged during a sneeze/cough or
from rough handling. Thus, respirators
worn in the presence of a potentially
infected patient or co-worker should be
disposed of as infectious waste, and
touching of the outside of the respirator
should be avoided.
In January, 2006, the Department of
Health and Human Services asked the
Institute of Medicine (IOM) to convene
a committee to conduct an assessment
of measures that can be taken that
would permit the reuse of disposable
N95 particulate filtering respirators in
healthcare settings and to report the
status of current knowledge about the
need and development of reusable N95
respirators for healthcare providers and
the general public. Some of the key
recommendations from that study were
that research studies should be
conducted to (1) understand the efficacy
of simple decontamination methods that
could be used without negative effects
on respirator integrity; and (2)
understand the risks associated with
handling a respirator that has been used
for protection against a viral threat (e.g.,
study the likelihood that the exterior
surface of the respirator might harbor
pathogenic microorganisms and thus
serve as a fomite).
This research project addresses the
major research gaps related to the
reusability of filtering facepiece
respirators (FFR) during an influenza
pandemic. NIOSH/NPPTL plans to
conduct a variety of tasks in this
research project, including: (1)
Determining the effect of
decontamination on FFR filtration
E:\FR\FM\26SEN1.SGM
26SEN1
56152
Federal Register / Vol. 71, No. 186 / Tuesday, September 26, 2006 / Notices
performance; (2) Development of a
standardized test protocol for measuring
the efficacy of a decontamination
procedure for FFR; (3) Measure the
survivability of a virus simulant trapped
on FFR; (4) Measurement of the
reaerosolization of a trapped virus
simulant on FFR; (5) Assess the efficacy
of various decontamination methods
suitable for FFR; (6) Determine the
effects of decontamination on the FFR
fit; and (7) produce a final report that
could be used to issue guidance
documents on FFR reuse.
FOR FURTHER INFORMATION CONTACT:
Jonathan Szalajda, telephone 412–386–
6627, or e-mail zfx1@cdc.gov.
Dated: September 19, 2006.
James D. Seligman,
Chief Information Officer, Centers for Disease
Control and Prevention.
[FR Doc. E6–15706 Filed 9–25–06; 8:45 am]
BILLING CODE 4163–18–P
Matters To Be Discussed: The meeting
will include expert review of science
and programs of the Disability and
Health Team.
Contact Person for More Information:
Esther Sumartojo, Associate Director for
Science, National Center on Birth
Defects and Developmental Disabilities,
CDC, 1600 Clifton Road, NE., Mailstop
E–87, Atlanta, GA 30333, Telephone
Number 404.498.3072.
The Director, Management Analysis
and Services Office, has been delegated
the authority to sign Federal Register
notices pertaining to announcements of
meetings and other committee
management activities, for both CDC
and the Agency for Toxic Substances
and Disease Registry.
Dated: September 18, 2006.
Alvin Hall,
Director, Management Analysis and Services
Office, Centers for Disease Control and
Prevention.
[FR Doc. E6–15719 Filed 9–25–06; 8:45 am]
BILLING CODE 4163–18–P
Centers for Disease Control and
Prevention
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Disease, Disability, and Injury
Prevention and Control Special
Emphasis Panel (SEP): Portfolio on the
Disability and Health Team of the
Division of Human Development and
Disability
pwalker on PRODPC60 with NOTICES
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Disease Control and
Prevention
In accordance with Section 10(a)(2) of
the Federal Advisory Committee Act
(Public Law 92–463), the Centers for
Disease Control and Prevention (CDC)
announces the following meeting:
Name: Disease, Disability, and Injury
Prevention and Control Special
Emphasis Panel (SEP): Portfolio on the
Disability and Health Team of the
Division of Human Development and
Disability.
Times and Dates:
6 p.m.–8 p.m., October 22, 2006
(Closed).
8 a.m.–5 p.m., October 23, 2006
(Closed).
8 a.m.–3 p.m., October 24, 2006
(Closed).
Place: National Center on Birth
Defects and Developmental Disabilities,
CDC, 12 Executive Park Drive, Atlanta,
Georgia 30329, Telephone Number
404.498.3013.
Status: The meeting will be closed to
the public in accordance with
provisions set forth in Section
552b(c)(4) and (6), Title 5 U.S.C., and
the Determination of the Director,
Management Analysis and Services
Office, CDC, pursuant to Public Law 92–
463.
VerDate Aug<31>2005
21:03 Sep 25, 2006
Jkt 208001
Diseases Transmitted Through the
Food Supply
Centers for Disease Control and
Prevention (CDC), Department of Health
and Human Services (HHS).
ACTION: Notice of annual update of list
of infectious and communicable
diseases that are transmitted through
handling the food supply and the
methods by which such diseases are
transmitted.
AGENCY:
SUMMARY: Section 103(d) of the
Americans with Disabilities Act of 1990,
Public Law 101–336, requires the
Secretary to publish a list of infectious
and communicable diseases that are
transmitted through handling the food
supply and to review and update the list
annually. The Centers for Disease
Control and Prevention (CDC) published
a final list on August 16, 1991 (56 FR
40897) and updates on September 8,
1992 (57 FR 40917); January 13, 1994
(59 FR 1949); August 15, 1996 (61 FR
42426); September 22, 1997 (62 FR
49518–9); September 15, 1998 (63 FR
49359), September 21, 1999 (64 FR
51127); September 27, 2000 (65 FR
58088), September 10, 2001 (66 FR
47030), and September 27, 2002 (67 FR
61109). The final list has been reviewed
in light of new information and has
been revised as set forth below.
PO 00000
Frm 00053
Fmt 4703
Sfmt 4703
September 26, 2006.
Dr.
Donald Sharp, National Center for
Infectious Diseases, Centers for Disease
Control and Prevention (CDC), 1600
Clifton Road, NE., Mailstop G–24,
Atlanta, Georgia 30333 Telephone: (404)
639–2213
SUPPLEMENTARY INFORMATION: Section
103(d) of the Americans with
Disabilities Act of 1990, 42 U.S.C.
12113(d), requires the Secretary of
Health and Human Services to:
1. Review all infectious and
communicable diseases which may be
transmitted through handling the food
supply;
2. Publish a list of infectious and
communicable diseases which are
transmitted through handling the food
supply;
3. Publish the methods by which such
diseases are transmitted; and,
4. Widely disseminate such
information regarding the list of
diseases and their modes of
transmissibility to the general public.
Additionally, the list is to be updated
annually. Since the last publication of
the list on October 4, 2004 (67 FR
61109), new information has been
reviewed and added. Norwalk and
Norwalk-like viruses, previously listed
in Part I, are now identified as
Noroviruses so as to conform with
current scientific nomenclature.
Sapoviruses have been added to Part II.
EFFECTIVE DATE:
FOR FURTHER INFORMATION CONTACT:
I. Pathogens Often Transmitted by Food
Contaminated by Infected Persons Who
Handle Food, and Modes of
Transmission of Such Pathogens
The contamination of raw ingredients
from infected food-producing animals
and cross-contamination during
processing are more prevalent causes of
foodborne disease than is contamination
of foods by persons with infectious or
contagious diseases. However, some
pathogens are frequently transmitted by
food contaminated by infected persons.
The presence of any one of the
following signs or symptoms in persons
who handle food may indicate infection
by a pathogen that could be transmitted
to others through handling the food
supply: Diarrhea, vomiting, open skin
sores, boils, fever, dark urine, or
jaundice. The failure of food-handlers to
wash hands (in situations such as after
using the toilet, handling raw meat,
cleaning spills, or carrying garbage, for
example), wear clean gloves, or use
clean utensils is responsible for the
foodborne transmission of these
pathogens. Non-foodborne routes of
transmission, such as from one person
to another, are also major contributors
E:\FR\FM\26SEN1.SGM
26SEN1
]]>Agencies
[Federal Register Volume 71, Number 186 (Tuesday, September 26, 2006)]
[Notices]
[Pages 56151-56152]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E6-15706]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
The National Institute for Occupational Safety and Health (NIOSH)
of the Centers for Disease Control and Prevention (CDC) Announcement
Opportunity for Businesses To Partner With National Institute for
Occupational Safety and Health (NIOSH) on a Research Project To
Evaluate the Reusability of Disposable Filtering Facepiece Respirators
(FFR) Used for Protection Against Infectious Aerosols
Authority: 29 U.S.C. Sections 651 et seq.
AGENCY: The National Institute for Occupational Safety and Health
(NIOSH), Centers for Disease Control and Prevention (CDC).
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The National Personal Protective Technology Laboratory
(NPPTL), NIOSH, is conducting research to determine the reusability of
filtering facepiece respirators (FFR) exposed to infectious aerosols.
One aim of this research is to address whether NIOSH-certified FFR are
suitable for reuse after decontamination. NIOSH proposes to study the
effects of decontaminating a diverse array of FFR including NIOSH-
certified N95, P100, and N95 filtering facepiece respirator/surgical
mask. This project will also study the survivability of a simulant
influenza virus on FFR. NIOSH plans to include in the research study
some of the respirator models that have been stockpiled by the U.S
government to be used in the event of an influenza pandemic. NIOSH also
plans to include models that have head straps versus those that do not
have head straps, as well as models with and without exhalation valves.
Through this announcement, NIOSH is seeking to identify FFR
products or prototypes that possess anti-viral or other novel
technologies that disinfect or sterilize infectious aerosols (e.g.,
viruses) as part of their materials of construction. Program funding
constraints may limit the number of candidate respirators that may be
included in the research program. NIOSH will give consideration to the
incorporation of novel anti-viral technologies into this research study
using the following hierarchy for selection of candidate FFR products
and prototypes: (1) The FFR proposed for consideration in this study
are commercially available and are currently certified to meeting 42
CFR part 84 requirements, (2) the FFR proposed for consideration is in
the process of being certified by NIOSH to meet 42 CFR part 84
requirements, (3) the FFR proposed for consideration are either a
prototype or a commercially available product that has not been
submitted to NIOSH for certification and the manufacturer submitting
the letter of interest has received NIOSH certification for other
respiratory protection products, and (4) the FFR prototype contains a
unique technology for disinfecting or sterilizing infectious aerosol
particles trapped on the exterior surface of the FFR and complements
the diversity of technologies already considered in the research
design.
Candidate companies will be evaluated based on their capability to
achieve the identified criteria in sufficient quantities for testing.
Candidates selected could be requested to enter into a Cooperative
Research and Development Agreement (CRADA). This announcement does not
obligate NIOSH to enter into a contractual agreement with any
respondents. NIOSH reserves the right to establish a partnership based
on scientific analysis and capabilities found by way of this
announcement or other searches, if determined to be in the best
interest of the government.
DATES: Submit letters of interest within 30 days after the date of
publication of this notice in the Federal Register.
ADDRESSES: Interested manufacturers should submit a letter of interest
with information about their capabilities to: NIOSH, National Personal
Protection Technology Laboratory, P.O. Box 18070, 626 Cochrans Mill
Road, Attn: Jonathan Szalajda, Pittsburgh, PA 15236, E-mail address:
zfx1@cdc.gov.
SUPPLEMENTARY INFORMATION: CDC recommends the use of disposable N95,
N99, or N100 filtering facepiece particulate respirators (FFR) as the
minimum level of respiratory protection against transmission of
influenza virus. During a respirator shortage, it is important to
consider whether a previously worn FFR can be used again. Reuse
guidelines in the NIOSH Guide to the Selection and Use of Particulate
Respirators Certified under 42 CFR 84 recommend reuse based on loading
of the filter and functioning of the respirator. Hospital settings tend
to have relatively low concentrations of particulates, but the
potential for infectious agents exists. Thus, reuse is more dependent
upon infection control procedures than on respirator loading
considerations. Respirators exposed to viruses are considered to be
potentially harmful because of the possibility for the respirator to
act as a fomite and the potential for the viral particle to become
dislodged during a sneeze/cough or from rough handling. Thus,
respirators worn in the presence of a potentially infected patient or
co-worker should be disposed of as infectious waste, and touching of
the outside of the respirator should be avoided.
In January, 2006, the Department of Health and Human Services asked
the Institute of Medicine (IOM) to convene a committee to conduct an
assessment of measures that can be taken that would permit the reuse of
disposable N95 particulate filtering respirators in healthcare settings
and to report the status of current knowledge about the need and
development of reusable N95 respirators for healthcare providers and
the general public. Some of the key recommendations from that study
were that research studies should be conducted to (1) understand the
efficacy of simple decontamination methods that could be used without
negative effects on respirator integrity; and (2) understand the risks
associated with handling a respirator that has been used for protection
against a viral threat (e.g., study the likelihood that the exterior
surface of the respirator might harbor pathogenic microorganisms and
thus serve as a fomite).
This research project addresses the major research gaps related to
the reusability of filtering facepiece respirators (FFR) during an
influenza pandemic. NIOSH/NPPTL plans to conduct a variety of tasks in
this research project, including: (1) Determining the effect of
decontamination on FFR filtration
[[Page 56152]]
performance; (2) Development of a standardized test protocol for
measuring the efficacy of a decontamination procedure for FFR; (3)
Measure the survivability of a virus simulant trapped on FFR; (4)
Measurement of the reaerosolization of a trapped virus simulant on FFR;
(5) Assess the efficacy of various decontamination methods suitable for
FFR; (6) Determine the effects of decontamination on the FFR fit; and
(7) produce a final report that could be used to issue guidance
documents on FFR reuse.
FOR FURTHER INFORMATION CONTACT: Jonathan Szalajda, telephone 412-386-
6627, or e-mail zfx1@cdc.gov.
Dated: September 19, 2006.
James D. Seligman,
Chief Information Officer, Centers for Disease Control and Prevention.
[FR Doc. E6-15706 Filed 9-25-06; 8:45 am]
BILLING CODE 4163-18-P
