National Cancer Institute; Amended Notice of Meeting, 51628 [06-7229]

Download as PDF 51628 Federal Register / Vol. 71, No. 168 / Wednesday, August 30, 2006 / Notices jlentini on PROD1PC65 with NOTICES Publication: T. M Sissung et al. Association of ABCB1 genotypes with paclitaxel-mediated neutropenia and peripheral neuropathy, To be submitted to Clinical Pharmacology and Therapy. Patent Status: U.S. Provisional Application No. 60/807,453 filed 14 Jul 2006 (HHS Reference No. E–237–2006/ 0–US–01). Licensing Status: Available for nonexclusive or exclusive licensing. Licensing Contact: David Lambertson, PhD; 301/435–4632; lambertsond@od.nih.gov. Collaborative Research Opportunity: The NCI Medical Oncology Branch is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize ABCB1 genotyping to predict paclitaxel toxicity. Please contact Betty Tong, PhD at 301–496–0477, tongb@mail.nih.gov for more information. Use of Grape Skin Extracts as AntiCancer Agents Description of Technology: The invention describes anti-tumor effects of extracts from grape skins. Grape skin extract and derivatives may therefore be useful as preventive or therapeutic agents against tumor development. Literature indicates that grape and red wine consumption may be inversely associated with prostate cancer risk. Moreover, to date there are no known grape skin extract-associated toxicities described. The current invention discloses that grape skin extract, or purified fractions thereof, inhibited metastatic growth in human prostate transformed cell lines. Specifically, grape skin extract induced cellular apoptosis via inhibition of the phosphatidylinositol 3-kinase (PI3-K)/ Akt survival pathway. Historically, anti-tumor effects of grapes were mainly attributed to resveratrol, a phytoalexin present in grapes, nuts and wild berries. However, resveratrol’s mechanism of anti-tumor action is distinct from that of grape skin extract, in that it arrests cell cycle division without significant induction of apoptosis. The current invention also provides for methods of treating patients with prostate cancer or persons at risk for developing prostate cancer with compositions that include grape skin extract or active anti-tumor fractions thereof. Development Status: Pre-clinical stage. Inventors: Tamaro Hudson and Jeffrey E. Green (NCI). Patent Status: U.S. Provisional Application No. 60/789,181 filed 03 VerDate Aug<31>2005 16:39 Aug 29, 2006 Jkt 208001 April 2006 (HHS Reference No. E–179– 2006/0–US–01). Licensing Status: Available for nonexclusive or exclusive licensing. Licensing Contact: David A. Lambertson, PhD; 301–435–4632; lambertsond@od.nih.gov. Collaborative Research Opportunity: The NCI’s Laboratory of Cell Regulation and Carcinogenesis is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact Patrick Twomey, PhD at 301– 496–0477 or twomeyp@mail.nih.gov for more information. Dated: August 23, 2006. Steven M. Ferguson, Director, Division of Technology Development and Transfer, Office of Technology Transfer, National Institutes of Health. [FR Doc. E6–14353 Filed 8–29–06; 8:45 am] September 13, 2006, 6 p.m., Doubletree Hotel, 8120 Wisconsin Ave., Bethesda, MD, 20814 which was published in the Federal Register on July 25, 2006. 71 FR 42098. The meeting notice is amended to reflect the change in hotel from the Doubletree Hotel, 8120 Wisconsin Ave., Bethesda, MD 20814 to the Clarion Hotel, 8400 Wisconsin Ave., Bethesda, MD 20814. The meeting is closed to the public. Dated: August 22, 2006. Anna Snouffer, Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–7229 Filed 8–29–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES BILLING CODE 4140–01–P National Institutes of Health DEPARTMENT OF HEALTH AND HUMAN SERVICES National Center on Minority Health and Health Disparities; Amended Notice of Meeting National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meting of the National Cancer Institute Special Emphasis Panel, September 11, 2006, 5 p.m. to September 13, 2006, 5 p.m. Doubletree Hotel Bethesda, 8120 Wisconsin Ave., Bethesda, MD, 20814 which was published in the Federal Register on July 25, 2006, 71 FR 42099. The meeting notice is amended to reflect the change in hotel from the Doubletree Hotel, 8120 Wisconsin Ave., Bethesda, MD 20814 to the Clarion Hotel, 8400 Wisconsin Ave., Bethesda, MD 20814. The meeting is closed to the public. Dated: August 22, 2006. Anna Snouffer, Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–7228 Filed 8–29–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Cancer Institute Special Emphasis Panel, September 11, 2006, 5 p.m. to PO 00000 Frm 00063 Fmt 4703 Sfmt 4703 Notice is hereby given of a change in the meeting of the National Advisory Council on Minority Health and Health Disparities, September 12, 2006, 8:30 a.m. to September 12, 2006, 5 p.m., National Institutes of Health, Two Democracy Plaza, 6707 Democracy Boulevard, Bethesda, MD, 20892 which was published in the Federal Register on August 18, 2006, 71 FR 47817. The meeting location changed to the Bethesda Marriott, 5151 Pooks Hill Rd., Bethesda, Maryland 20814. The meeting is partially closed to the public. Dated: August 23, 2006. Anna Snouffer Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–7227 Filed 8–29–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meetings. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and E:\FR\FM\30AUN1.SGM 30AUN1

Agencies

[Federal Register Volume 71, Number 168 (Wednesday, August 30, 2006)]
[Notices]
[Page 51628]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 06-7229]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Cancer Institute; Amended Notice of Meeting

    Notice is hereby given of a change in the meeting of the National 
Cancer Institute Special Emphasis Panel, September 11, 2006, 5 p.m. to 
September 13, 2006, 6 p.m., Doubletree Hotel, 8120 Wisconsin Ave., 
Bethesda, MD, 20814 which was published in the Federal Register on July 
25, 2006. 71 FR 42098.
    The meeting notice is amended to reflect the change in hotel from 
the Doubletree Hotel, 8120 Wisconsin Ave., Bethesda, MD 20814 to the 
Clarion Hotel, 8400 Wisconsin Ave., Bethesda, MD 20814. The meeting is 
closed to the public.

    Dated: August 22, 2006.
Anna Snouffer,
Acting Director, Office of Federal Advisory Committee Policy.
[FR Doc. 06-7229 Filed 8-29-06; 8:45 am]
BILLING CODE 4140-01-M

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