Welcome to the United States Survey, 40139 [E6-11135]
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Federal Register / Vol. 71, No. 135 / Friday, July 14, 2006 / Notices
acid or with iopanioc acid. These
macromolecular imaging agents have
clearance properties that mimic the
pharmacokinetic properties of coadministrated drugs, so as to be useful
in quantifying the range and dosage
level of therapeutic drugs using MR
imaging.
E–206–2000 ‘‘Method for increasing
the distribution of therapeutic agents:’’
‘‘Method for increasing the distribution
of nucleic acids.’’ The invention
pertains to the reliance of therapies on
the local parenchymal delivery of
macromolecules or nucleic acids for
success. However, the volume of
distribution of many of these potential
therapeutic agents is restricted by their
interactions with the extracellular
matrix and cellular receptors. Heparinsulfate proteoglycans are cell surface
components which bind to an array of
molecules such as growth factors,
cytokines and chemokines and viruses
such as cytomegalovirus, herpes
simplex virus and HIV. The invention
provides a method of dramatically
increasing the volume of distribution
and effectiveness of certain therapeutic
agents after local delivery by the use of
facilitating agents as described in
Neuroreport. 2001 Jul 3;12(9):1961–4
entitled ‘‘Convection enhanced delivery
of AAV–2 combined with heparin
increases TK gene transfer in the rat
brain’’ and in Exp Neurol. 2001
Mar;168(1):155–61 entitled ‘‘Heparin
coinfusion during convection-enhanced
delivery (CED) increases the distribution
of the glial-derived neurotrophic factor
(GDNF) ligand family in rat striatum
and enhances the pharmacological
activity of neurturin.’’ These methods
are especially useful when used in
conjunction with technology described
and claimed in the convection enhanced
delivery technology claimed in U.S.
patent 5,720,720
The prospective exclusive license will
be royalty bearing and will comply with
the terms and conditions of 35 U.S.C.
209 and 37 CFR 404.7. The prospective
exclusive license may be granted unless,
within sixty (60) days from the date of
this published notice. NIH receives
written evidence and argument that
establishes that the grant of the license
would not be consistent with the
requirements of 35 U.S.C. 209 and 37
CFR 404.7.
Properly filed competing applications
for a license filed in response to this
notice will be treated as objections to
the contemplated license. Comments
and objections submitted in response to
this notice will not be made available
for public inspection, and, to the extent
permitted by law, will not be released
VerDate Aug<31>2005
17:44 Jul 13, 2006
Jkt 208001
under the Freedom of Information Act,
5 U.S.C. 552.
Dated: July 5, 2006.
David R. Sadowski,
Acting Director, Division of Technology
Development and Transfer, Office of
Technology Transfer, National Institutes of
Health.
[FR Doc. 06–6213 Filed 7–13–06; 8:45 am]
BILLING CODE 4140–01–M
DEPARTMENT OF HOMELAND
SECURITY
Office of the Secretary
Welcome to the United States Survey
Office of the Secretary, Office
of Policy, Private Sector Office, DHS.
ACTION: Emergency submission to OMB,
comment request.
AGENCY:
The Department of Homeland, Office
of the Secretary, Private Sector Office
has submitted the following (see below)
information collection request (ICR),
utilizing emergency review procedures,
to the Office of Management and Budget
(OMB) for review and clearance in
accordance with the Paperwork
Reduction Act of 1995 (Pub. L. 104–13,
44 U.S.C. chapter 35). OMB approval
has been requested by July 30, 2006. A
copy of this ICR, with applicable
supporting documentation, may be
obtained by calling the Departmental
Clearance Officer.
Comments and questions about the
ICR listed below should be forwarded to
the Office of Information and Regulatory
Affairs, Attn: OMB Desk Officer for the
Department of Homeland Security,
Office of Management and Budget,
Room 10235, Washington, DC 20503
(OMB phone number). The Office of
Management and Budget is particularly
interested in comments which: [set
asterisks]
• Evaluate whether the proposed
collection of information is necessary
for the proper performance of the
functions of the agency, including
whether the information will have
practical utility;
• Evaluate the accuracy of the
agency’s estimate of the burden of the
proposed collection of information,
including the validity of the
methodology and assumptions used;
• Enhance the quality, utility, and
clarify of the information to be
collected; and
• Minimize the burden of the
collection of information on those who
are to respond, including through the
use of appropriate automated,
electronic, mechanical, or other
PO 00000
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40139
technological collection techniques or
other forms of information technology,
e.g., permitting electronic submissions
of responses. [end asterisks]
Agency: Department of Homeland
Security, Office of the Secretary, Office
of Policy, Private Sector Office.
Title: Welcome to the United States
Survey.
OMB Number: 1601–NEW.
Frequency: One-time collection.
Affected Public: Foreign visitors into
the U.S.
Number of Respondents: 939.
Estimated Time Per Respondent: 5
minutes.
Total Burden Hours: 78.25 hours.
Total Burden Cost (capital/startup):
$0.00.
Total Burden Cost (operating/
maintaining): $0.00.
Description: The Department of
Homeland Security (DHS), Office of
Policy, Private Sector Office in
conjunction with Customs and Border
Protection (CBP) and Research Triangle
Institute, International, will interview
foreign visitors entering the United
States at four southern border ports of
entry, three northern border ports of
entry and four airport ports of entry
before the Labor Day holiday in August
2006. This survey will measure how
CBP is serving the American public
with vigilance and integrity, while
providing courteous and helpful
treatment to visitors, immigrants and
travelers. Additionally, this survey will
further the Rice-Chertoff Initiative as
has been announced by evaluating the
two model airports (Dulles International
Airport, Chantilly, VA, and Houston
International Airport, Houston, TX) for
baseline information as well as how
welcomed foreign visitors feel upon
entering the United States and
interacting with a DHS Customs and
Border Protection officer.
Scott Charbo,
Chief Information Officer.
[FR Doc. E6–11135 Filed 7–13–06; 8:45 am]
BILLING CODE 4410–10–P
DEPARTMENT OF HOMELAND
SECURITY
Coast Guard
[USCG–2006–25312]
Meeting of the Office of Boating
Safety’s Recreational Boating Safety
Strategic Planning Panel
Coast Guard, DHS.
Notice of meeting.
AGENCY:
ACTION:
SUMMARY: The Coast Guard’s Office of
Boating Safety is sponsoring a panel of
E:\FR\FM\14JYN1.SGM
14JYN1
]]>Agencies
[Federal Register Volume 71, Number 135 (Friday, July 14, 2006)]
[Notices]
[Page 40139]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E6-11135]
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DEPARTMENT OF HOMELAND SECURITY
Office of the Secretary
Welcome to the United States Survey
AGENCY: Office of the Secretary, Office of Policy, Private Sector
Office, DHS.
ACTION: Emergency submission to OMB, comment request.
-----------------------------------------------------------------------
The Department of Homeland, Office of the Secretary, Private Sector
Office has submitted the following (see below) information collection
request (ICR), utilizing emergency review procedures, to the Office of
Management and Budget (OMB) for review and clearance in accordance with
the Paperwork Reduction Act of 1995 (Pub. L. 104-13, 44 U.S.C. chapter
35). OMB approval has been requested by July 30, 2006. A copy of this
ICR, with applicable supporting documentation, may be obtained by
calling the Departmental Clearance Officer.
Comments and questions about the ICR listed below should be
forwarded to the Office of Information and Regulatory Affairs, Attn:
OMB Desk Officer for the Department of Homeland Security, Office of
Management and Budget, Room 10235, Washington, DC 20503 (OMB phone
number). The Office of Management and Budget is particularly interested
in comments which: [set asterisks]
Evaluate whether the proposed collection of information is
necessary for the proper performance of the functions of the agency,
including whether the information will have practical utility;
Evaluate the accuracy of the agency's estimate of the
burden of the proposed collection of information, including the
validity of the methodology and assumptions used;
Enhance the quality, utility, and clarify of the
information to be collected; and
Minimize the burden of the collection of information on
those who are to respond, including through the use of appropriate
automated, electronic, mechanical, or other technological collection
techniques or other forms of information technology, e.g., permitting
electronic submissions of responses. [end asterisks]
Agency: Department of Homeland Security, Office of the Secretary,
Office of Policy, Private Sector Office.
Title: Welcome to the United States Survey.
OMB Number: 1601-NEW.
Frequency: One-time collection.
Affected Public: Foreign visitors into the U.S.
Number of Respondents: 939.
Estimated Time Per Respondent: 5 minutes.
Total Burden Hours: 78.25 hours.
Total Burden Cost (capital/startup): $0.00.
Total Burden Cost (operating/maintaining): $0.00.
Description: The Department of Homeland Security (DHS), Office of
Policy, Private Sector Office in conjunction with Customs and Border
Protection (CBP) and Research Triangle Institute, International, will
interview foreign visitors entering the United States at four southern
border ports of entry, three northern border ports of entry and four
airport ports of entry before the Labor Day holiday in August 2006.
This survey will measure how CBP is serving the American public with
vigilance and integrity, while providing courteous and helpful
treatment to visitors, immigrants and travelers. Additionally, this
survey will further the Rice-Chertoff Initiative as has been announced
by evaluating the two model airports (Dulles International Airport,
Chantilly, VA, and Houston International Airport, Houston, TX) for
baseline information as well as how welcomed foreign visitors feel upon
entering the United States and interacting with a DHS Customs and
Border Protection officer.
Scott Charbo,
Chief Information Officer.
[FR Doc. E6-11135 Filed 7-13-06; 8:45 am]
BILLING CODE 4410-10-P
