National Institute of Mental Health; Notice of Closed Meetings, 37587-37588 [06-5884]

Download as PDF Federal Register / Vol. 71, No. 126 / Friday, June 30, 2006 / Notices rwilkins on PROD1PC63 with NOTICES_1 Collaborative Research Opportunity: The Laboratory of Molecular Pharmacology at the National Cancer Institute is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize diamidine derivatives, particularly optimizing them for therapeutic use. Please contact Lisa Finkelstein at 301/451–7458 for more information. Use of Tetracyclines as Anti-Cancer Agents Description of Technology: The invention describes compositions of tetracycline compounds and their derivatives as having anticancer activity, as well as methods of treating cancer. Tetracyclines are commonly used as antibiotics; however, testing of these compounds in a high throughput screening system revealed certain derivatives to be potent inhibitors of tyrosyl-DNA-phosphodiesterase (Tdp1). Camptothecins are effective Topoisomerase I (Top1) inhibitors, and two derivatives (Topotecan and Camptosar) are currently approved for treatment of ovarian and colorectal cancer. Camptothecins damage DNA by trapping covalent complexes between the Top1 catalytic tyrosine and the 3’end of the broken DNA. Tdp1 repairs Top1-DNA covalent complexes by hydrolyzing the tyrosyl-DNA bond. This can reduce the effectiveness of camptothecins as anti-cancer agents. In addition, Tdp1 repairs free-radicalmediated DNA breaks. As disclosed in the instant technology, tetracyclines have the potential to enhance the anti-neoplastic activity of Top1 inhibitors by reducing repair of Top1-DNA lesions through inhibition of Tdp1. Inhibition of Tdp1 may also reduce repair of DNA breaks and increase the rate of apoptosis in cancer cells, making them potential anti-cancer agents on their own. Development Status: Pre-clinical stage. Inventors: Yves Pommier (NCI), Christophe Marchand (NCI), Laurent Thibaut (NCI). Publications: 1. Z Liao et al. ‘‘Inhibition of human Tyrosyl-DNA Phosphodiesterase (Tdp1) by aminoglycoside antibiotics and ribosome inhibitors.’’ Mol Pharmacol. 2006 Apr 17; Epub ahead of print, doi:10.1124/mol.105.021865. 2. Y Pommier. ‘‘Camptothecins and topoisomerase I: a foot in the door. Targeting the genome beyond topoisomerase I with camptothecins and novel anticancer drugs: importance of DNA replication, repair and cell cycle VerDate Aug<31>2005 16:30 Jun 29, 2006 Jkt 208001 checkpoints.’’ Curr Med Chem Anticancer Agents. 2004 Sep; 4(5):429– 34. Review. 3. Y Pommier et al. ‘‘Repair of and checkpoint response to topoisomerase I mediated DNA damage.’’ Mutat Res. 2003 Nov 27;532(1–2):173–203. Review. Patent Status: U.S. Provisional Application No. 60/786,746 filed 27 Mar 2006 (HHS Reference No. E–097–2006/ 0-US–01). Licensing Status: Available for nonexclusive or exclusive licensing. Licensing Contact: David A. Lambertson, PhD.; 301/435–4632; lambertsond@od.nih.gov. Collaborative Research Opportunity: The Laboratory of Molecular Pharmacology at the National Cancer Institute is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize tetracycline derivatives, particularly optimizing them for therapeutic use. Please contact Lisa Finkelstein at 301/451–7458 for more information. Dated: June 23, 2006. David R. Sadowski, Acting Director, Division of Technology Development and Transfer, Office of Technology Transfer, National Institutes of Health. [FR Doc. 06–5882 Filed 6–29–06; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Mental Health; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6). Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Mental Health Special Emphasis Panel, Cooperative Drug Development Group For The Treatment Of Mental Illness. Date: July 11, 2006. PO 00000 Frm 00061 Fmt 4703 Sfmt 4703 37587 Time: 10 a.m. to 12 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Yong Yao, PhD, Scientific Review Administrator, Division of Extramural Activities National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6149, MSC 9606, Bethesda, MD 20892–9606. 301–443–6102. yaoy3@mail.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. Name of Committee: National Institute of Mental Health Special Emphasis Panel, Rapid Assessment Post-Impact of Disaster. Date: July 11, 2006. Time: 3 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Tracy Waldeck, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6132, MSC 9608, Bethesda, MD 20852–9609. (301) 435–0322. waldeckt@mail.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. Name of Committee: National Institute of Mental Health Special Emphasis Panel, MLSCN Assay Review. Date: July 20, 2006. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Holiday Inn Chevy Chase, 5520 Wisconsin Avenue, Chevy Chase, MD 20815. Contact Person: Yong Yao, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6149, MSC 9606, Bethesda, MD 20892–9606, (301) 443–6102. yaoy3@mail.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. Name of Committee: National Institute of Mental Health Special Emphasis Panel; Mood/Anxiety Research Review. Date: July 24, 2006. Time: 1 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Christopher S. Sarampote, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental Health, NIH, E:\FR\FM\30JNN1.SGM 30JNN1 37588 Federal Register / Vol. 71, No. 126 / Friday, June 30, 2006 / Notices Neuroscience Center, 6001 Executive Blvd., Room 6148, MSC 9608, Bethesda, MD 20892– 9608. (301) 443–1959. csarampo@mail.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.242, Mental Health Research Grants; 93.281, Scientist Development Award, Scientist Development Award for Clinicians, and Research Scientist Award; 93.282, Mental Health National Research Service Awards for Research Training, National Institutes of Health, HHS) Dated: June 22, 2006. Linda Payne, Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–5884 Filed 6–29–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Mental Health; Notice of Closed Meetings rwilkins on PROD1PC63 with NOTICES_1 Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Mental Health Special Emphasis Panel; Bipolar/Schizophrenia Research Review. Date: July 19, 2006. Time: 9 a.m. to 12 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 208952 (Telephone Conference Call). Contact Person: Christopher S. Sarampote, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6148, MSC 9608, Bethesda, MD 20892– 9608. 301–443–1959. csarampo@mail.nih.gov. Name of Committee: National Institute of Mental Health Special Emphasis Panel; NIMH Psychiatric Genetics Review. Date: July 21, 2006. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. VerDate Aug<31>2005 16:30 Jun 29, 2006 Jkt 208001 Place: Embassy Suites at the Chevy Chase Pavillion, 4300 Military Road, NW., Washington, DC 20015. Contact Person: Bettina D. Osborn, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental Health, National Institutes of Health, 6001 Executive Blvd., Room 6154, MSC 9609, Rockville, MD 20892–9609. 301–443–1178. acunab@mail.nih.gov. Name of Committee: National Institute of Mental Health Special Emphasis Panel; Fellowships and dissertation grants II. Date: July 24, 2006. Time: 1 p.m. to 1:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Marina Broitman, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6153, MSC 9608, Bethesda, MD 20892–9608. 301–402–8152. mbroitma@mail.nih.gov. Name of Committee: National Institute of Mental Health Special Emphasis Panel; Fellowships and dissertation grants. Date: July 24, 2006. Time: 1:30 p.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Marina Broitman, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6153, MSC 9608, Bethesda, MD 20892–9608. 301–402–8152. mbroitma@mail.nih.gov. Name of Committee: National Institute of Mental Health Special Emphasis Panel; Child-Interventions Research Conflicts Review. Date: July 27, 2006. Time: 10 a.m. to 1 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person: Christopher S. Sarampote, PhD, Scientific Review Administrator, Division of Extramural Activities, National Institute of Mental Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6148, MSC 9608, Bethesda, MD 20892– 9608. 301–443–1959. csarampo@mail.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.242, Mental Health Research Grants; 93.281, Scientist Development Award, Scientist Development Award for Clinicians, and Research Scientist Award; 93.282, Mental Health National Research Service Awards for Research Training, National Institutes of Health, HHS) PO 00000 Frm 00062 Fmt 4703 Sfmt 4703 Dated: June 22, 2006. Linda Payne, Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–5887 Filed 6–29–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Center for Scientific Review Special Emphasis Panel, June 26, 2006, 8:30 a.m. to June 26, 2006, 6 p.m., Double Tree Rockville, 1750 Rockville, Pike, Rockville, MD, 20852 which was published in the Federal Register on May 23, 2006, 71 FR 29660– 29661, The meeting will be held at the Bethesda Marriott Hotel, 5151 Pooks Hill Road, Bethesda, MD 20814. The meeting date and time remain the same. The meeting is closed to the public. Dated: June 21, 2006. Linda Payne, Acting Director, Office ofFederal Advisory Committee Policy. [FR Doc. 06–5885 Filed 6–29–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Cancer Detection and Imaging SBIR. Date: June 29, 2006. Time: 2 p.m. to 5 p.m. E:\FR\FM\30JNN1.SGM 30JNN1

Agencies

[Federal Register Volume 71, Number 126 (Friday, June 30, 2006)]
[Notices]
[Pages 37587-37588]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 06-5884]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Institute of Mental Health; Notice of Closed Meetings

    Pursuant to section 10(d) of the Federal Advisory Committee Act, as 
amended (5 U.S.C. Appendix 2), notice is hereby given of the following 
meetings.
    The meetings will be closed to the public in accordance with the 
provisions set forth in sections 552b(c)(4) and 552b(c)(6). Title 5 
U.S.C., as amended. The grant applications and the discussions could 
disclose confidential trade secrets or commercial property such as 
patentable material, and personal information concerning individuals 
associated with the grant applications, the disclosure of which would 
constitute a clearly unwarranted invasion of personal privacy.

    Name of Committee: National Institute of Mental Health Special 
Emphasis Panel, Cooperative Drug Development Group For The Treatment 
Of Mental Illness.
    Date: July 11, 2006.
    Time: 10 a.m. to 12 p.m.
    Agenda: To review and evaluate grant applications.
    Place: National Institutes of Health, Neuroscience Center, 6001 
Executive Boulevard, Rockville, MD 20852 (Telephone Conference 
Call).
    Contact Person: Yong Yao, PhD, Scientific Review Administrator, 
Division of Extramural Activities National Institute of Mental 
Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6149, 
MSC 9606, Bethesda, MD 20892-9606. 301-443-6102. yaoy3@mail.nih.gov.
    This notice is being published less than 15 days prior to the 
meeting due to the timing limitations imposed by the review and 
funding cycle.

    Name of Committee: National Institute of Mental Health Special 
Emphasis Panel, Rapid Assessment Post-Impact of Disaster.
    Date: July 11, 2006.
    Time: 3 p.m. to 4 p.m.
    Agenda: To review and evaluate grant applications.
    Place: National Institutes of Health, Neuroscience Center, 6001 
Executive Boulevard, Rockville, MD 20852 (Telephone Conference 
Call).
    Contact Person: Tracy Waldeck, PhD, Scientific Review 
Administrator, Division of Extramural Activities, National Institute 
of Mental health, NIH, Neuroscience Center, 6001 Executive Blvd., 
Room 6132, MSC 9608, Bethesda, MD 20852-9609. (301) 435-0322. 
waldeckt@mail.nih.gov.
    This notice is being published less than 15 days prior to the 
meeting due to the timing limitations imposed by the review and 
funding cycle.

    Name of Committee: National Institute of Mental Health Special 
Emphasis Panel, MLSCN Assay Review.
    Date: July 20, 2006.
    Time: 8 a.m. to 5 p.m.
    Agenda: To review and evaluate grant applications.
    Place: Holiday Inn Chevy Chase, 5520 Wisconsin Avenue, Chevy 
Chase, MD 20815.
    Contact Person: Yong Yao, PhD, Scientific Review Administrator, 
Division of Extramural Activities, National Institute of Mental 
Health, NIH, Neuroscience Center, 6001 Executive Blvd., Room 6149, 
MSC 9606, Bethesda, MD 20892-9606, (301) 443-6102. 
yaoy3@mail.nih.gov.
    This notice is being published less than 15 days prior to the 
meeting due to the timing limitations imposed by the review and 
funding cycle.

    Name of Committee: National Institute of Mental Health Special 
Emphasis Panel; Mood/Anxiety Research Review.
    Date: July 24, 2006.
    Time: 1 p.m. to 4 p.m.
    Agenda: To review and evaluate grant applications.
    Place: National Institutes of Health, Neuroscience Center, 6001 
Executive Boulevard, Rockville, MD 20852 (Telephone Conference 
Call).
    Contact Person: Christopher S. Sarampote, PhD, Scientific Review 
Administrator, Division of Extramural Activities, National Institute 
of Mental Health, NIH,

[[Page 37588]]

Neuroscience Center, 6001 Executive Blvd., Room 6148, MSC 9608, 
Bethesda, MD 20892-9608. (301) 443-1959. csarampo@mail.nih.gov.

(Catalogue of Federal Domestic Assistance Program Nos. 93.242, 
Mental Health Research Grants; 93.281, Scientist Development Award, 
Scientist Development Award for Clinicians, and Research Scientist 
Award; 93.282, Mental Health National Research Service Awards for 
Research Training, National Institutes of Health, HHS)

    Dated: June 22, 2006.
Linda Payne,
Acting Director, Office of Federal Advisory Committee Policy.
[FR Doc. 06-5884 Filed 6-29-06; 8:45 am]
BILLING CODE 4140-01-M
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.