National Toxicology Program (NTP); NTP Workshop: Biomarkers for Toxicology Studies, 30433 [E6-8172]
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Federal Register / Vol. 71, No. 102 / Friday, May 26, 2006 / Notices
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Toxicology Program (NTP);
NTP Workshop: Biomarkers for
Toxicology Studies
National Institute of
Environmental Health Sciences
(NIEHS), National Institutes of Health
(NIH).
ACTION: Workshop announcement and
request for comments.
jlentini on PROD1PC65 with NOTICES
AGENCY:
SUMMARY: For more than a quarter
century, the NTP testing program has
provided extensive and useful scientific
information for predicting human health
hazards and protecting public health.
The NTP periodically conducts reviews
of models used in its testing program to
critically analyze their predictive power
and determine whether study protocols
should be altered. As part of this effort,
the NTP is convening a workshop titled
‘‘Biomarkers for Toxicology Studies.’’
The meeting will be held on September
20–21, 2006, at the NIEHS in Research
Triangle Park, NC.
The workshop will include plenary
sessions and three simultaneous
breakout group sessions for in-depth
discussion. The workshop’s overall goal
is to identify biomarkers for
carbohydrate/lipid metabolism and lung
and cardiac function and then evaluate
their utility for inclusion in rodent
toxicology studies to better characterize
endpoints of environmentally induced
diseases or biological processes related
to disease etiology. This meeting is open
to the public with time set aside for
public comments during the plenary
session on the first day. The public is
invited to attend the breakout groups as
observers.
A copy of the agenda and any
additional information about the
workshop, including background
materials, public comments, and invited
participants, will be posted on the NTP
Web site when available (see NTP Web
site https://ntp.niehs.nih.gov select
‘‘Calendar of Upcoming Events’’).
DATES: The workshop will be held on
September 20–21, 2006, and begin each
day at 8:30 a.m. and end at
approximately 5 p.m. on September 20
and approximately 12:30 p.m. on
September 21.
Comments: Written comments should
be received by September 6, 2006, to
allow time for adequate review before
the meeting. Individuals wishing to
make oral public comments are asked to
contact Ms. Denise Lasko (see FOR
FURTHER INFORMATION CONTACT below)
VerDate Aug<31>2005
16:12 May 25, 2006
Jkt 208001
by September 6, 2006, and if possible,
to send a copy of the statement or
talking points at that time.
Registration: Individuals who plan to
attend are encouraged to register online
at the NTP Web site https://
ntp.niehs.nih.gov/ select ‘‘Calendar of
Upcoming Events’’ as soon as possible
because seating is limited.
Persons needing special assistance,
such as sign language interpretation or
other reasonable accommodation in
order to attend, should contact 919–
541–2475 voice, 919–541–4644 TTY
(text telephone), through the Federal
TTY Relay System at 800–877–8339, or
by e-mail to niehsoeeo@niehs.nih.gov.
Requests should be made at least 7 days
in advance of the event.
ADDRESSES: The workshop will be held
in the Rodbell Auditorium, Rall
Building at the NIEHS, 111 T.W.
Alexander Drive, Research Triangle
Park, NC 27709.
FOR FURTHER INFORMATION CONTACT:
Requests for public comment and any
other correspondence should be
submitted to Ms. Denise Lasko (NIEHS,
P.O. Box 12233, MD A3–01, Research
Triangle Park, NC 27709; telephone:
919–541–0530, fax: 919–541–0295; or email: lasko@niehs.nih.gov).
SUPPLEMENTARY INFORMATION:
Background
The term biomarker is often used to
refer to indicators of exposure and
response in biological systems.
Biomarker measurements can
potentially be used as indicators of
disease etiology or biological function;
however, their utility is a function of
how well the biomarker is understood.
In addition, biomarkers measured in
animal models should be applicable to
humans.
The plenary session on the first day
will include overview talks. Each
breakout group will address the
identification of biomarkers for lung
function, cardiac function, or
carbohydrate/lipid metabolism and
discuss their possible inclusion in
rodent toxicology studies to better
characterize endpoints of
environmentally induced diseases or
biological processes related to disease
etiology. The breakout groups will
present their findings during plenary on
September 21 followed by a general,
open discussion.
Request for Comments
Each organization is allowed one
speaker during the public comment
period. At least 7 minutes will be
allotted to each speaker and, if time
permits, may be extended to 10 minutes.
PO 00000
Frm 00069
Fmt 4703
Sfmt 4703
30433
Registration for oral comments will also
be available onsite, although time
allowed for presentation by on-site
registrants may be less than that for preregistered speakers and will be
determined by the number of persons
who register at the meeting.
Written statements can supplement
and may expand the oral presentation.
If registering onsite and reading from
written text, please bring 50 copies of
the statement for distribution and to
supplement the record. Written
comments received in response to this
notice will be posted on the meeting
page for this event on the NTP Web site
(https://ntp.niehs.nih.gov select
‘‘Calendar of Upcoming Events.’’
Persons submitting written comments
should include their name, affiliation,
mailing address, phone, fax, e-mail, and
sponsoring organization (if any) with
the document.
Dated: May 17, 2006.
Samuel H. Wilson,
Deputy Director, National Institute of
Environmental Health Sciences and National
Toxicology Program.
[FR Doc. E6–8172 Filed 5–25–06; 8:45 am]
BILLING CODE 4140–01–P
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Comments are invited on: (a) Whether
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E:\FR\FM\26MYN1.SGM
26MYN1
]]>Agencies
[Federal Register Volume 71, Number 102 (Friday, May 26, 2006)]
[Notices]
[Page 30433]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E6-8172]
[[Page 30433]]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Toxicology Program (NTP); NTP Workshop: Biomarkers for
Toxicology Studies
AGENCY: National Institute of Environmental Health Sciences (NIEHS),
National Institutes of Health (NIH).
ACTION: Workshop announcement and request for comments.
-----------------------------------------------------------------------
SUMMARY: For more than a quarter century, the NTP testing program has
provided extensive and useful scientific information for predicting
human health hazards and protecting public health. The NTP periodically
conducts reviews of models used in its testing program to critically
analyze their predictive power and determine whether study protocols
should be altered. As part of this effort, the NTP is convening a
workshop titled ``Biomarkers for Toxicology Studies.'' The meeting will
be held on September 20-21, 2006, at the NIEHS in Research Triangle
Park, NC.
The workshop will include plenary sessions and three simultaneous
breakout group sessions for in-depth discussion. The workshop's overall
goal is to identify biomarkers for carbohydrate/lipid metabolism and
lung and cardiac function and then evaluate their utility for inclusion
in rodent toxicology studies to better characterize endpoints of
environmentally induced diseases or biological processes related to
disease etiology. This meeting is open to the public with time set
aside for public comments during the plenary session on the first day.
The public is invited to attend the breakout groups as observers.
A copy of the agenda and any additional information about the
workshop, including background materials, public comments, and invited
participants, will be posted on the NTP Web site when available (see
NTP Web site https://ntp.niehs.nih.gov select ``Calendar of Upcoming
Events'').
DATES: The workshop will be held on September 20-21, 2006, and begin
each day at 8:30 a.m. and end at approximately 5 p.m. on September 20
and approximately 12:30 p.m. on September 21.
Comments: Written comments should be received by September 6, 2006,
to allow time for adequate review before the meeting. Individuals
wishing to make oral public comments are asked to contact Ms. Denise
Lasko (see FOR FURTHER INFORMATION CONTACT below) by September 6, 2006,
and if possible, to send a copy of the statement or talking points at
that time.
Registration: Individuals who plan to attend are encouraged to
register online at the NTP Web site https://ntp.niehs.nih.gov/ select
``Calendar of Upcoming Events'' as soon as possible because seating is
limited.
Persons needing special assistance, such as sign language
interpretation or other reasonable accommodation in order to attend,
should contact 919-541-2475 voice, 919-541-4644 TTY (text telephone),
through the Federal TTY Relay System at 800-877-8339, or by e-mail to
niehsoeeo@niehs.nih.gov. Requests should be made at least 7 days in
advance of the event.
ADDRESSES: The workshop will be held in the Rodbell Auditorium, Rall
Building at the NIEHS, 111 T.W. Alexander Drive, Research Triangle
Park, NC 27709.
FOR FURTHER INFORMATION CONTACT: Requests for public comment and any
other correspondence should be submitted to Ms. Denise Lasko (NIEHS,
P.O. Box 12233, MD A3-01, Research Triangle Park, NC 27709; telephone:
919-541-0530, fax: 919-541-0295; or e-mail: lasko@niehs.nih.gov).
SUPPLEMENTARY INFORMATION:
Background
The term biomarker is often used to refer to indicators of exposure
and response in biological systems. Biomarker measurements can
potentially be used as indicators of disease etiology or biological
function; however, their utility is a function of how well the
biomarker is understood. In addition, biomarkers measured in animal
models should be applicable to humans.
The plenary session on the first day will include overview talks.
Each breakout group will address the identification of biomarkers for
lung function, cardiac function, or carbohydrate/lipid metabolism and
discuss their possible inclusion in rodent toxicology studies to better
characterize endpoints of environmentally induced diseases or
biological processes related to disease etiology. The breakout groups
will present their findings during plenary on September 21 followed by
a general, open discussion.
Request for Comments
Each organization is allowed one speaker during the public comment
period. At least 7 minutes will be allotted to each speaker and, if
time permits, may be extended to 10 minutes. Registration for oral
comments will also be available onsite, although time allowed for
presentation by on-site registrants may be less than that for pre-
registered speakers and will be determined by the number of persons who
register at the meeting.
Written statements can supplement and may expand the oral
presentation. If registering onsite and reading from written text,
please bring 50 copies of the statement for distribution and to
supplement the record. Written comments received in response to this
notice will be posted on the meeting page for this event on the NTP Web
site (https://ntp.niehs.nih.gov select ``Calendar of Upcoming Events.''
Persons submitting written comments should include their name,
affiliation, mailing address, phone, fax, e-mail, and sponsoring
organization (if any) with the document.
Dated: May 17, 2006.
Samuel H. Wilson,
Deputy Director, National Institute of Environmental Health Sciences
and National Toxicology Program.
[FR Doc. E6-8172 Filed 5-25-06; 8:45 am]
BILLING CODE 4140-01-P
